TRIPLE C reporting principles for case study evaluations of the role of context in complex interventions
Guidance and reporting principles such as CONSORT (for randomised trials) and PRISMA (for systematic reviews) have greatly improved the reporting, discoverability, transparency and consistency of published res... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 13, 2023 Category: Research Authors: Sara E. Shaw, Sara Paparini, Jamie Murdoch, Judith Green, Trisha Greenhalgh, Benjamin Hanckel, Hannah M. James, Mark Petticrew, Gary W. Wood and Chrysanthi Papoutsi Tags: Research Source Type: research

The unrecognized role of fidelity in effectiveness-implementation hybrid trials: simulation study and guidance for implementation researchers
Effectiveness-implementation hybrid designs are a relatively new approach to evaluate efficacious interventions in real-world settings while concurrently gathering information on the implementation. Interventi... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 13, 2023 Category: Research Authors: Diana Trutschel, Catherine Blatter, Michael Simon, Daniela Holle, Sven Reuther and Thekla Brunkert Tags: Research Source Type: research

The Trial within Cohorts (TwiCs) study design in oncology: experience and methodological reflections
A Trial within Cohorts (TwiCs) study design is a trial design that uses the infrastructure of an observational cohort study to initiate a randomized trial. Upon cohort enrollment, the participants provide cons... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 13, 2023 Category: Research Authors: Rob Kessels, Anne M. May, Miriam Koopman and Kit C. B. Roes Tags: Research Source Type: research

Research recruitment and consent methods in a pandemic: a qualitative study of COVID-19 patients ’ perspectives
Virtual data collection methods and consent procedures adopted in response to the COVID-19 pandemic enabled continued research activities, but also introduced concerns about equity, inclusivity, representation... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 11, 2023 Category: Research Authors: Serena S Small, Erica Lau, Kassandra McFarlane, Patrick M Archambault, Holly Longstaff and Corinne M Hohl Tags: Research Source Type: research

Exploring flexible polynomial regression as a method to align routine clinical outcomes with daily data capture through remote technologies
Clinical outcomes are normally captured less frequently than data from remote technologies, leaving a disparity in volumes of data from these different sources. To align these data, flexible polynomial regress... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 11, 2023 Category: Research Authors: Nicole Filipow, Eleanor Main, Gizem Tanriver, Emma Raywood, Gwyneth Davies, Helen Douglas, Aidan Laverty and Sanja Stanojevic Tags: Research Source Type: research

Multiple imputation methods for missing multilevel ordinal outcomes
Multiple imputation (MI) is an established technique for handling missing data in observational studies. Joint modelling (JM) and fully conditional specification (FCS) are commonly used methods for imputing mu... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 9, 2023 Category: Research Authors: Mei Dong and Aya Mitani Tags: Research Source Type: research

Quantitative bias analysis in practice: review of software for regression with unmeasured confounding
Failure to appropriately account for unmeasured confounding may lead to erroneous conclusions. Quantitative bias analysis (QBA) can be used to quantify the potential impact of unmeasured confounding or how muc... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 4, 2023 Category: Research Authors: Emily Kawabata, Kate Tilling, Rolf H. H. Groenwold and Rachael A. Hughes Tags: Research Source Type: research

Interdisciplinary sport injury research and the integration of qualitative and quantitative data
To understand and prevent sport injuries, scholars have employed different scientific approaches and research methods. Traditionally, this research has been monodisciplinary, relying on one subdiscipline of sp... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 3, 2023 Category: Research Authors: S.E Hausken-Sutter, K Boije af Genn äs, A Schubring, S Grau, J Jungmalm and N Barker-Ruchti Tags: Research Source Type: research

Utilization of five data mining algorithms combined with simplified preprocessing to establish reference intervals of thyroid-related hormones for non-elderly adults
Despite the extensive research on data mining algorithms, there is still a lack of a standard protocol to evaluate the performance of the existing algorithms. Therefore, the study aims to provide a novel proce... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 2, 2023 Category: Research Authors: Jian Zhong, Chaochao Ma, Li ’an Hou, Yicong Yin, Fang Zhao, Yingying Hu, Ailing Song, Danchen Wang, Lei Li, Xinqi Cheng and Ling Qiu Tags: Research Source Type: research

Correction: Real ‑world data: a brief review of the methods, applications, challenges and opportunities
(Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - May 2, 2023 Category: Research Authors: Fang Liu and Demosthenes Panagiotakos Tags: Correction Source Type: research

Bayesian regularization to predict neuropsychiatric adverse events in smoking cessation with pharmacotherapy
Research on risk factors for neuropsychiatric adverse events (NAEs) in smoking cessation with pharmacotherapy is scarce. We aimed to identify predictors and develop a prediction model for risk of NAEs in smoki... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - April 29, 2023 Category: Research Authors: Van Thi Thanh Truong, Charles Green, Claudia Pedroza, Lu-Yu Hwang, Suja S. Rajan, Robert Suchting, Paul Cinciripini, Rachel F. Tyndale and Caryn Lerman Tags: Research Source Type: research

Effect of important modifiers on harmful effects in evidence synthesis practice of adverse events were insufficiently investigated: an empirical investigation
In this study, we in... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - April 28, 2023 Category: Research Authors: Xiaoqin Zhou, Xi Yang, Fei Cai, Li Wang, Chang Xu and Pengli Jia Tags: Research Source Type: research

Reporting of flow diagrams in randomised controlled trials published in periodontology and implantology: a survey
Item 13 of the CONSORT guidelines recommends documentation of the participant flow in randomised clinical trials (RCTs) using a diagram. In the medical literature, the reporting of the flow of participants in ... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - April 27, 2023 Category: Research Authors: Hanns-Gustav Julius Meyer, Nikolaos Pandis, Jadbinder Seehra and Clovis Mariano Faggion Jr Tags: Research Source Type: research

Researchers in rheumatology should avoid categorization of continuous predictor variables
Rheumatology researchers often categorize continuous predictor variables. We aimed to show how this practice may alter results from observational studies in rheumatology. (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - April 26, 2023 Category: Research Authors: Zubeyir Salis, Blanca Gallego and Amanda Sainsbury Tags: Research Source Type: research

The Preventiometer - reliability of a cardiovascular multi-device measurement platform and its measurement agreement with a cohort study
Multimedia multi-device measurement platforms may make the assessment of prevention-related medical variables with a focus on cardiovascular outcomes more attractive and time-efficient. The aim of the studies ... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - April 24, 2023 Category: Research Authors: Martin Junge, Markus Kr üger, Dietlind L. Wahner-Roedler, Brent A. Bauer, Marcus Dörr, Martin Bahls, Jean-François Chenot, Reiner Biffar and Carsten O. Schmidt Tags: Research Source Type: research