Fezolinetant impact on health-related quality of life for vasomotor symptoms due to the menopause: Pooled data from SKYLIGHT 1 and SKYLIGHT 2 randomised controlled trials
CONCLUSIONS: Fezolinetant treatment was associated with improvement in overall QoL, measured by MENQoL, and work productivity, measured by WPAI-VMS. A high proportion receiving fezolinetant felt VMS were 'much better' based on PGI-C VMS responder analysis.PMID:38320967 | DOI:10.1111/1471-0528.17773 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 6, 2024 Category: OBGYN Authors: Antonio Cano Rossella E Nappi Nanette Santoro Petra Stute Martin Blogg Marci L English Antonia Morga Ludmila Scrine Emad Siddiqui Faith D Ottery Source Type: research

The Management of Nausea and Vomiting in Pregnancy and Hyperemesis Gravidarum (Green-top Guideline No. 69)
BJOG. 2024 Feb 4. doi: 10.1111/1471-0528.17739. Online ahead of print.ABSTRACTAn objective and validated index of nausea and vomiting such as the Pregnancy-Unique Quantification of Emesis (PUQE) and HyperEmesis Level Prediction (HELP) tools can be used to classify the severity of NVP and HG. [Grade C] Ketonuria is not an indicator of dehydration and should not be used to assess severity. [Grade A] There are safety and efficacy data for first line antiemetics such as anti (H1) histamines, phenothiazines and doxylamine/pyridoxine (Xonvea®) and they should be prescribed initially when required for NVP and HG (Appendix III). ...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 4, 2024 Category: OBGYN Authors: Catherine Nelson-Piercy Caitlin Dean Manjeet Shehmar Roger Gadsby Margaret O'Hara Kenneth Hodson Melanie Nana Royal College of Obstetricians and Gynaecologists Source Type: research

Duration of rupture of membranes and microbiome transmission to the newborn: A prospective study
CONCLUSIONS: Maternal and newborn microbiomes were greatly affected by labour variables. Duration of rupture of membranes, even in non-elective caesarean sections, should be considered in epidemiological and microbiological studies, as well as in vaginal seeding practices.PMID:38311451 | DOI:10.1111/1471-0528.17774 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 4, 2024 Category: OBGYN Authors: Ma ïté Ribère Virginie Lemieux-Labont é Thomas Pincez Elie Azria Fran çois-Joseph Lapointe Source Type: research

Calcium supplementation for the prevention of pre-eclampsia: Challenging the evidence from meta-analyses
CONCLUSIONS: In assessment of the effect of calcium supplementation on pre-eclampsia risk, the naive focus on the mean of the random-effects meta-analysis in the presence of substantial heterogeneity is highly misleading.PMID:38302677 | DOI:10.1111/1471-0528.17769 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 1, 2024 Category: OBGYN Authors: David Wright Alan Wright Laura A Magee Peter Von Dadelszen Kypros H Nicolaides Source Type: research

The difference in extracellular matrix metabolism in women with and without pelvic organ prolapse: A systematic review and meta-analysis
CONCLUSIONS: Patients with POP have lower expression of COLI and TIMP-1 and higher expression of COLIII and MMPs compared with non-POP cases, but further studies are required to investigate in specified anatomical sites.PMID:38291948 | DOI:10.1111/1471-0528.17768 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 31, 2024 Category: OBGYN Authors: Zhao Tian Qiutong Li Xiuqi Wang Zhijing Sun Source Type: research

Exposure to microplastics and human reproductive outcomes: A systematic review
CONCLUSIONS: There is a need for high-quality observational studies to assess the effects of microplastics on human reproductive health.PMID:38287142 | DOI:10.1111/1471-0528.17756 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 29, 2024 Category: OBGYN Authors: Kathryn Hunt Anna Davies Abigail Fraser Christy Burden Amy Howell Kirsten Buckley Sam Harding Danya Bakhbakhi Source Type: research

Risk of stillbirth after a previous caesarean delivery: A Swedish nationwide cohort study
CONCLUSIONS: This study confirms that a CD is associated with an increased risk of subsequent stillbirth, with a greater risk among pre-labour CD. This association is not solely mediated by increases in intrapartum asphyxia, uterine rupture or attempted VBAC. Further research is needed to understand this association, but these findings might help healthcare providers to reach optimal decisions regarding mode of birth, particularly when CD is unnecessary.PMID:38287170 | DOI:10.1111/1471-0528.17760 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 29, 2024 Category: OBGYN Authors: Sukainah Y Al Khalaf Alexander E P Heazell Marius Kublickas Karolina Kublickiene Ali S Khashan Source Type: research

Maternal and neonatal morbidity associated with Fetal Pillow ® use at full dilatation caesarean: A retrospective cohort
CONCLUSIONS: Despite the relatively large size of this study, it could not rule out either a positive or a negative association between use of the Fetal Pillow® and uterine extensions, major uterine incision extensions, and neonatal morbidity. Randomised controlled trial evidence is required to assess efficacy.PMID:38287196 | DOI:10.1111/1471-0528.17772 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 29, 2024 Category: OBGYN Authors: Lynn C Sadler John M D Thompson Jane M Alsweiler Christopher J D McKinlay Robin Cronin Erena Browne Thea Baillie-Bellew Amanda D Harvey Meghan G Hill Source Type: research

The carbon footprint of different modes of birth in the UK and the Netherlands: An exploratory study using life cycle assessment
CONCLUSION: The carbon footprint of a caesarean is higher than for a vaginal birth if analgesia is excluded, but this is very sensitive to the analgesia used; use of nitrous oxide with oxygen multiplies the carbon footprint of vaginal birth 25-fold. Alternative methods of pain relief or nitrous oxide destruction systems would lead to a substantial improvement in carbon footprint. Although clinical need and maternal choice are paramount, protocols should consider the environmental impact of different choices.PMID:38272843 | DOI:10.1111/1471-0528.17771 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 25, 2024 Category: OBGYN Authors: Nienke A Spil Kim E van Nieuwenhuizen Rachel Rowe Jim G Thornton Elizabeth Murphy Evelyn Verheijen Clifford L Shelton Alexander E P Heazell Source Type: research

Perinatal depression in transgender and gender expansive individuals
BJOG. 2024 Jan 25. doi: 10.1111/1471-0528.17757. Online ahead of print.NO ABSTRACTPMID:38272844 | DOI:10.1111/1471-0528.17757 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 25, 2024 Category: OBGYN Authors: Blaire C Pingeton Sherryl H Goodman Justin A Lavner Kat LaFever Noah Marchuck Source Type: research

Miscarriage after SARS-CoV-2 vaccination: A request to report more details of the regression models and analyses
BJOG. 2024 Jan 22. doi: 10.1111/1471-0528.17767. Online ahead of print.NO ABSTRACTPMID:38247342 | DOI:10.1111/1471-0528.17767 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 22, 2024 Category: OBGYN Authors: Retsef Levi Efrat Schurr Source Type: research

A sensorised surgical glove to improve training and detection of obstetric anal sphincter injury: A preclinical study on a pig model
CONCLUSION: In this preliminary study, the sensorised glove accurately detected anal sphincter injury in a pig model. Future plans include its clinical translation, starting with an in-human study on postpartum women, to determine whether it can accurately detect different types of obstetric anal sphincter injury in vivo.PMID:38247347 | DOI:10.1111/1471-0528.17762 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 22, 2024 Category: OBGYN Authors: Shireen R Jaufuraully Carmen Salvadores Fernandez Nadine Abbas Adrien Desjardins Manish K Tiwari Anna L David Dimitrios Siassakos Source Type: research

Continuous wound infiltration can become one effective choice to control postoperative pain: A response to F. S. Xue et  al
BJOG. 2024 Jan 22. doi: 10.1111/1471-0528.17766. Online ahead of print.NO ABSTRACTPMID:38247358 | DOI:10.1111/1471-0528.17766 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 22, 2024 Category: OBGYN Authors: Mayu Kuriyama Hirotaka Nakamura Serabi Tanabe Yoshihiko Morikawa Tetsuji Kaneko Source Type: research

Impact of cash transfers on the association between prenatal exposures to high temperatures and low birthweight: Retrospective analysis from the LEAP 1000 study
CONCLUSIONS: Our study found increased odds of LBW with high weekly average temperatures throughout pregnancy and the preconception period and demonstrate mitigated effects by the LEAP 1000 CT program. More evidence on the potential of CTs to serve as adaptation interventions in low- and middle-income countries is needed to protect pregnant persons and their infants from the impacts of climate change.PMID:38238994 | DOI:10.1111/1471-0528.17761 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 19, 2024 Category: OBGYN Authors: Sarah LaPointe Pauline Mendola Shao Lin Lili Tian Ana Bonell Clement Adamba Tia Palermo Source Type: research

Maternal exposure to metals and time-to-pregnancy: The MIREC cohort study
CONCLUSION: Blood concentrations of metals at typical levels of exposure among Canadian pregnant women were not associated with TTP or infertility. Further studies are needed to assess the role of lead, if any, on TTP.PMID:38239019 | DOI:10.1111/1471-0528.17759 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 19, 2024 Category: OBGYN Authors: Priya Premranjith Will King Jillian Ashley-Martin Michael M Borghese Maryse Bouchard Warren Foster Tye E Arbuckle Maria P Velez Source Type: research