Corrigendum to "Sensitive sugar detection using 4-aminophenylboronic acid modified graphene" [Biosens. Bioelectron. 50 (2013) 331-337]
Biosens Bioelectron. 2023 Dec 26:115928. doi: 10.1016/j.bios.2023.115928. Online ahead of print.NO ABSTRACTPMID:38151364 | DOI:10.1016/j.bios.2023.115928 (Source: Biosensors and Bioelectronics)
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Qi Wang Izabela Kaminska Joanna Niedziolka-Jonsson Marcin Opallo Musen Li Rabah Boukherroub Sabine Szunerits Source Type: research

Imaging mRNA in vitro and in vivo with nanofirecracker probes via intramolecular hybridization chain reaction
Biosens Bioelectron. 2023 Dec 25;248:115973. doi: 10.1016/j.bios.2023.115973. Online ahead of print.ABSTRACTHybridization chain reaction (HCR) based enzyme-free amplification techniques have recently been developed for the visualization of intracellular messenger RNA (mRNA). However, the slow kinetics and potential interference with the intricate biological environments hinder its application in the clinic and in vivo. Herein, we designed a nanofirecracker probe-based strategy using intramolecular hybridization chain reaction (IHCR) amplifier for rapid, efficient, sensitive, specific detection and imaging of survivin mRNA ...
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Huo Xu Yanhui Zheng Jingjing Xie Wei Duan Lixue Yu Ruimiao Lin Chen-Chen Li Lee Jia Source Type: research

Hollow-microsphere-integrated optofluidic immunochip for myocardial infarction biomarker microanalysis
Biosens Bioelectron. 2023 Dec 25;248:115970. doi: 10.1016/j.bios.2023.115970. Online ahead of print.ABSTRACTThis work developed an optofluidic immunochip that uses whispering gallery mode with fiber laser enhancement, for the rapid detection of a key biomarker cardiac troponin I for acute myocardial infarction (AMI). The immunochip adopted an innovative design, using perforated hollow glass microspheres (HGMS) as carriers, with antibodies immobilized on the inner surface of the HGMS, thereby achieving ultra-low sample consumption. The performance of the immunochip was improved by fiber laser, including spectral width compr...
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Panpan Niu Junfeng Jiang Kun Liu Xin Zhou Shuang Wang Tianhua Xu Tong Wang Yongle Li Qing Yang Tiegen Liu Source Type: research

A portable all-in-one microfluidic device with real-time colorimetric LAMP for HPV16 and HPV18 DNA point-of-care testing
Biosens Bioelectron. 2023 Dec 22;248:115968. doi: 10.1016/j.bios.2023.115968. Online ahead of print.ABSTRACTScreening for high-risk human papillomavirus (HPV) infection is one of the most important preventative measures for cervical cancer. However, fast, convenient, and low-cost HPV detection remains challenging, especially in resource-limited settings. Here, we report a portable all-in-one device (PAD) for point-of-care testing (POCT) for HPV16 and HPV18 DNA in cervical swabs. The PAD was engineered to integrate modules for extraction-free sample lysis, loop-mediated isothermal amplification (LAMP) with lyophilized reage...
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Hao Bai Yuqing Liu Linbo Gao Tao Wang Xiaoli Zhang Jie Hu Lisha Ding Yueting Zhang Qian Wang Lei Wang Jianlong Li Zhifeng Zhang Yang Wang Chenlan Shen Binwu Ying Xiaoyu Niu Wenchuang Hu Source Type: research

High-throughput screening of human mercury exposure based on a low-cost naked eye-recognized biosensing platform
Biosens Bioelectron. 2023 Dec 21;248:115961. doi: 10.1016/j.bios.2023.115961. Online ahead of print.ABSTRACTWhole-cell biosensors could be helpful for in situ disease diagnosis. However, their use in analyzing biological samples has been hindered by unstable responses, low signal enhancement, and growth inhibition in complex media. Here, we offered a solution by building a visual whole-cell biosensor for urinary mercury determination. With deoxyviolacein as the preferred signal for the mercury biosensor for the first time, it enabled the quantitative detection of urinary mercury with a favorable linear range from 1.57 to 1...
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Bing-Chan Ma Yan Guo Yi-Ran Lin Juan Zhang Xiao-Qiang Wang Wen-Qi Zhang Jin-Gan Luo Yu-Ting Chen Nai-Xing Zhang Qing Lu Chang-Ye Hui Source Type: research

A sandwich-type dual-mode biosensor based on graphdiyne and DNA nanoframework for ultra-sensitive detection of CD142 gene
Biosens Bioelectron. 2023 Dec 24;248:115962. doi: 10.1016/j.bios.2023.115962. Online ahead of print.ABSTRACTThalassemia is a globally prevalent single-gene blood disorder, with nearly 7% of the world's population being carriers. Therefore, the development of specific and sensitive methods for thalassemia detection holds significant importance. Herein, a sandwich-type electrochemical/colorimetric dual-mode biosensor is developed based on gold nanoparticles (AuNPs)/graphdiyne (GDY) and DNA nanoframeworks for ultra-sensitive detection of CD142 gene associated with sickle cell anemia. Utilizing AuNPs/GDY as the substrate elect...
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Shiyu Liu Jinyue Shi Yu Lin Hu Luo Yeyu Wu Jun Yan Xuecai Tan Ke-Jing Huang Source Type: research

Biomineralization-powered integrated immunoprobe and its application in Immunochromatographic assay
Biosens Bioelectron. 2023 Dec 20;248:115945. doi: 10.1016/j.bios.2023.115945. Online ahead of print.ABSTRACTImmunochromatographic assay (ICA) has attracted widespread attention owing to its advantages of economy, simplicity, and rapidity. However, the synthesis of immunoprobes is still limited by complicated design ideas and multistep operations from preparing nanoparticles to conjugating monoclonal antibodies (mAb) onto nanoparticles. Inspired by the biomineralization of zeolitic imidazolate framework-8 (ZIF-8), we proposed a strategy for the rapid synthesis of an integrated immunoprobe (ZIF-8@QDs-mAb), achieving a one-st...
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Xi Mei Gan Zhang Tingting Liu Hong Hu Xiaocui Lai Wenyao Chen Yumeng Wang Juan Peng Weihua Lai Source Type: research

Corrigendum to "Sensitive sugar detection using 4-aminophenylboronic acid modified graphene" [Biosens. Bioelectron. 50 (2013) 331-337]
Biosens Bioelectron. 2023 Dec 26:115928. doi: 10.1016/j.bios.2023.115928. Online ahead of print.NO ABSTRACTPMID:38151364 | DOI:10.1016/j.bios.2023.115928 (Source: Biosensors and Bioelectronics)
Source: Biosensors and Bioelectronics - December 27, 2023 Category: Biotechnology Authors: Qi Wang Izabela Kaminska Joanna Niedziolka-Jonsson Marcin Opallo Musen Li Rabah Boukherroub Sabine Szunerits Source Type: research

Microbial biofilms for self-powered noncontact sensing
Biosens Bioelectron. 2023 Dec 14;247:115924. doi: 10.1016/j.bios.2023.115924. Online ahead of print.ABSTRACTNoncontact sensing technology plays a vital role in the intelligent human-machine interface, as the essential medium for exchanging information between human and electronic devices. To date, several inorganic materials-based noncontact sensing techniques have been used to accurately detect touch, electrical property, and physical motion. However, limited available materials, dependence on additional power supplies, and poor power production performance, have seriously obstructed the practical applications of nonconta...
Source: Biosensors and Bioelectronics - December 26, 2023 Category: Biotechnology Authors: Yongji Ma Bin Li Guoping Ren Zhao Wang Shungui Zhou Qichang Hu Christopher Rensing Source Type: research

Electrophoretic deposition of Ru(bpy) < sub > 3 < /sub > < sup > 2+ < /sup > in vertically-ordered silica nanochannels: A solid-state electrochemiluminescence sensor for prolidase assay
Biosens Bioelectron. 2023 Dec 22;247:115967. doi: 10.1016/j.bios.2023.115967. Online ahead of print.ABSTRACTProlidase (PLD) plays a crucial role as a dipeptidase in various physiological processes, specifically involved in the cleavage of proline-containing dipeptides for efficient recycling of proline. The accurate determination of PLD activity holds significant importance in clinical diagnosis. Herein, a solid-state electrochemiluminescence (ECL) biosensor was developed to address the urgent need for PLD assay. The Ru(bpy)32+ was electrophoretically deposited within the nanochannels of vertically-ordered mesoporous silic...
Source: Biosensors and Bioelectronics - December 26, 2023 Category: Biotechnology Authors: Weiqiang Yang Jiajing Xu Qingda Yao Xiaoguang Xu Xiaoping Chen Jiancong Ni Qingxiang Wang Zhenyu Lin Source Type: research

Enhanced performance of enzymes confined in biocatalytic hydrogen-bonded organic frameworks for sensing of glutamate in the central nervous system
Biosens Bioelectron. 2023 Dec 21;247:115963. doi: 10.1016/j.bios.2023.115963. Online ahead of print.ABSTRACTGlutamate (Glu) is a key excitatory neurotransmitter associated with various neurological disorders in the central nervous system, so its measurement is vital to both basic research and biomedical application. In this work, we propose the first example of using biocatalytic hydrogen-bonded organic frameworks (HOFs) as the hosting matrix to encapsulate glutamate oxidase (GLOD) via a de novo approach, fabricating a cascaded-enzyme nanoreactor for Glu biosensing. In this design, the ferriporphyrin ligands can assemble t...
Source: Biosensors and Bioelectronics - December 26, 2023 Category: Biotechnology Authors: Chang Ye Tianci Zhou Ying Deng Shuai Wu Tianyu Zeng Jie Yang Yun Stone Shi Yongmei Yin Genxi Li Source Type: research

Recent advancements of fluorescent biosensors using semisynthetic probes
Biosens Bioelectron. 2023 Dec 10;247:115862. doi: 10.1016/j.bios.2023.115862. Online ahead of print.ABSTRACTFluorescent biosensors are crucial experimental tools for live-cell imaging and the quantification of different biological analytes. Fluorescent protein (FP)-based biosensors are widely used for imaging applications in living systems. However, the use of FP-based biosensors is hindered by their large size, poor photostability, and laborious genetic manipulations required to improve their properties. Recently, semisynthetic fluorescent biosensors have been developed to address the limitations of FP-based biosensors us...
Source: Biosensors and Bioelectronics - December 26, 2023 Category: Biotechnology Authors: Shahi Imam Reja Masafumi Minoshima Yuichiro Hori Kazuya Kikuchi Source Type: research

Demethylation-activated light-up dual-color RNA aptamersensor for label-free detection of multiple demethylases in lung tissues
Biosens Bioelectron. 2023 Dec 21;247:115966. doi: 10.1016/j.bios.2023.115966. Online ahead of print.ABSTRACTMethylation is one of the most prevalent epigenetic modifications in natural organisms, and the processes of methylation and demethylation are closely associated with cell growth, differentiation, gene transcription and expression. Abnormal methylation may lead to various human diseases including cancers. Simultaneous analysis of multiple DNA demethylases remains a huge challenge due to the requirement of diverse substrate probes and scarcity of proper signal transduction strategies. Herein, we propose a sensitive an...
Source: Biosensors and Bioelectronics - December 26, 2023 Category: Biotechnology Authors: Xiao-Wen Liu Ning-Ning Zhao Hui-Min Yuan Dong-Ling Li Meng Liu Chun-Yang Zhang Source Type: research

2D Z-scheme ZnIn < sub > 2 < /sub > S < sub > 4 < /sub > /g-C < sub > 3 < /sub > N < sub > 4 < /sub > heterojunction based on photoelectrochemical immunosensor with enhanced carrier separation for sensitive detection of CEA
Biosens Bioelectron. 2023 Dec 17;247:115926. doi: 10.1016/j.bios.2023.115926. Online ahead of print.ABSTRACTSemiconducting materials based on photoelectrochemical (PEC) sensors have been widely utilized for detection. Meanwhile, the sensitivity of the PEC sensor was limited by low-efficiency carrier separation. Thus, a novel sandwich-type PEC bioimmunosensing based on 2D Z-scheme ZnIn2S4/g-C3N4 heterojunction as a photosensitive material and BiVO4 as a photoquencher was designed for the sensitive detection of carcinoembryonic antigen (CEA). Firstly, the 2D ZnIn2S4/g-C3N4 structure provided a multitude of activated sites wh...
Source: Biosensors and Bioelectronics - December 26, 2023 Category: Biotechnology Authors: Yiran Bo Linrong Li Pei Miao Chengfang Li Jing Chang Yang Zhang Yanfeng Lv Xiaofeng Yang Jing Zhang Mei Yan Source Type: research

Microbial biofilms for self-powered noncontact sensing
Biosens Bioelectron. 2023 Dec 14;247:115924. doi: 10.1016/j.bios.2023.115924. Online ahead of print.ABSTRACTNoncontact sensing technology plays a vital role in the intelligent human-machine interface, as the essential medium for exchanging information between human and electronic devices. To date, several inorganic materials-based noncontact sensing techniques have been used to accurately detect touch, electrical property, and physical motion. However, limited available materials, dependence on additional power supplies, and poor power production performance, have seriously obstructed the practical applications of nonconta...
Source: Biosensors and Bioelectronics - December 26, 2023 Category: Biotechnology Authors: Yongji Ma Bin Li Guoping Ren Zhao Wang Shungui Zhou Qichang Hu Christopher Rensing Source Type: research