Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm
Biosci Rep. 2023 Nov 10:BSR20230718. doi: 10.1042/BSR20230718. Online ahead of print.ABSTRACTAbdominal aortic aneurysm (AAA) represents a debilitating vascular disease characterized by aortic dilatation and wall rupture if it remains untreated. We aimed to determine the effects of Ang 1-7 in a murine model of AAA and to investigate the molecular mechanisms involved. 8-10 weeks old apolipoprotein E-deficient mice (ApoEKO) were infused with Ang II (1.44 mg/kg/day, s.c.) and treated with Ang 1-7 (0.576 mg/kg/day, i.p.). Echocardiographic and histological analyses showed abdominal aortic dilatation and extracellular matrix rem...
Source: Bioscience Reports - November 10, 2023 Category: Biomedical Science Authors: Anshul S Jadli Karina P Gomes Noura N Ballasy Tishani Methsala Wijesuriya Darrell Belke Paul W M Fedak Vaibhav B Patel Source Type: research
Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm
Biosci Rep. 2023 Nov 10:BSR20230718. doi: 10.1042/BSR20230718. Online ahead of print.ABSTRACTAbdominal aortic aneurysm (AAA) represents a debilitating vascular disease characterized by aortic dilatation and wall rupture if it remains untreated. We aimed to determine the effects of Ang 1-7 in a murine model of AAA and to investigate the molecular mechanisms involved. 8-10 weeks old apolipoprotein E-deficient mice (ApoEKO) were infused with Ang II (1.44 mg/kg/day, s.c.) and treated with Ang 1-7 (0.576 mg/kg/day, i.p.). Echocardiographic and histological analyses showed abdominal aortic dilatation and extracellular matrix rem...
Source: Bioscience Reports - November 10, 2023 Category: Biomedical Science Authors: Anshul S Jadli Karina P Gomes Noura N Ballasy Tishani Methsala Wijesuriya Darrell Belke Paul W M Fedak Vaibhav B Patel Source Type: research
Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm
Biosci Rep. 2023 Nov 10:BSR20230718. doi: 10.1042/BSR20230718. Online ahead of print.ABSTRACTAbdominal aortic aneurysm (AAA) represents a debilitating vascular disease characterized by aortic dilatation and wall rupture if it remains untreated. We aimed to determine the effects of Ang 1-7 in a murine model of AAA and to investigate the molecular mechanisms involved. 8-10 weeks old apolipoprotein E-deficient mice (ApoEKO) were infused with Ang II (1.44 mg/kg/day, s.c.) and treated with Ang 1-7 (0.576 mg/kg/day, i.p.). Echocardiographic and histological analyses showed abdominal aortic dilatation and extracellular matrix rem...
Source: Bioscience Reports - November 10, 2023 Category: Biomedical Science Authors: Anshul S Jadli Karina P Gomes Noura N Ballasy Tishani Methsala Wijesuriya Darrell Belke Paul W M Fedak Vaibhav B Patel Source Type: research
Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm
Biosci Rep. 2023 Nov 10:BSR20230718. doi: 10.1042/BSR20230718. Online ahead of print.ABSTRACTAbdominal aortic aneurysm (AAA) represents a debilitating vascular disease characterized by aortic dilatation and wall rupture if it remains untreated. We aimed to determine the effects of Ang 1-7 in a murine model of AAA and to investigate the molecular mechanisms involved. 8-10 weeks old apolipoprotein E-deficient mice (ApoEKO) were infused with Ang II (1.44 mg/kg/day, s.c.) and treated with Ang 1-7 (0.576 mg/kg/day, i.p.). Echocardiographic and histological analyses showed abdominal aortic dilatation and extracellular matrix rem...
Source: Bioscience Reports - November 10, 2023 Category: Biomedical Science Authors: Anshul S Jadli Karina P Gomes Noura N Ballasy Tishani Methsala Wijesuriya Darrell Belke Paul W M Fedak Vaibhav B Patel Source Type: research
Retraction: SMARCB1 expression is a novel diagnostic and prognostic biomarker for osteosarcoma
Biosci Rep. 2023 Nov 30;43(11):BSR-2021-2446_RET. doi: 10.1042/BSR-2021-2446_RET.NO ABSTRACTPMID:37921048 | DOI:10.1042/BSR-2021-2446_RET (Source: Bioscience Reports)
Source: Bioscience Reports - November 3, 2023 Category: Biomedical Science Source Type: research
Retraction: SMARCB1 expression is a novel diagnostic and prognostic biomarker for osteosarcoma
Biosci Rep. 2023 Nov 30;43(11):BSR-2021-2446_RET. doi: 10.1042/BSR-2021-2446_RET.NO ABSTRACTPMID:37921048 | DOI:10.1042/BSR-2021-2446_RET (Source: Bioscience Reports)
Source: Bioscience Reports - November 3, 2023 Category: Biomedical Science Source Type: research
Retraction: SMARCB1 expression is a novel diagnostic and prognostic biomarker for osteosarcoma
Biosci Rep. 2023 Nov 30;43(11):BSR-2021-2446_RET. doi: 10.1042/BSR-2021-2446_RET.NO ABSTRACTPMID:37921048 | DOI:10.1042/BSR-2021-2446_RET (Source: Bioscience Reports)
Source: Bioscience Reports - November 3, 2023 Category: Biomedical Science Source Type: research
Retraction: SMARCB1 expression is a novel diagnostic and prognostic biomarker for osteosarcoma
Biosci Rep. 2023 Nov 30;43(11):BSR-2021-2446_RET. doi: 10.1042/BSR-2021-2446_RET.NO ABSTRACTPMID:37921048 | DOI:10.1042/BSR-2021-2446_RET (Source: Bioscience Reports)
Source: Bioscience Reports - November 3, 2023 Category: Biomedical Science Source Type: research
Retraction: SMARCB1 expression is a novel diagnostic and prognostic biomarker for osteosarcoma
Biosci Rep. 2023 Nov 30;43(11):BSR-2021-2446_RET. doi: 10.1042/BSR-2021-2446_RET.NO ABSTRACTPMID:37921048 | DOI:10.1042/BSR-2021-2446_RET (Source: Bioscience Reports)
Source: Bioscience Reports - November 3, 2023 Category: Biomedical Science Source Type: research
Retraction: SMARCB1 expression is a novel diagnostic and prognostic biomarker for osteosarcoma
Biosci Rep. 2023 Nov 30;43(11):BSR-2021-2446_RET. doi: 10.1042/BSR-2021-2446_RET.NO ABSTRACTPMID:37921048 | DOI:10.1042/BSR-2021-2446_RET (Source: Bioscience Reports)
Source: Bioscience Reports - November 3, 2023 Category: Biomedical Science Source Type: research
MIR938 rs2505901 T & gt;C polymorphism is associated with increased neuroblastoma risk in Chinese children
This study revealed that the MIR938 rs2505901 T>C polymorphism may be a potential risk factor for neuroblastoma in Chinese children. In the long term, conducting large and diverse sample studies from different ethnicities will indeed be crucial in determining the role of MIR938 polymorphisms in NB risk. By including individuals from various ethnic backgrounds, researchers can account for potential genetic variations that may exist between populations.PMID:37905791 | DOI:10.1042/BSR20231223 (Source: Bioscience Reports)
Source: Bioscience Reports - October 31, 2023 Category: Biomedical Science Authors: Susu Jiang Xiuhong Sun Xinxin Zhang Chunlei Zhou Haiyan Wu Jing He Wenhan Yang Source Type: research
MIR938 rs2505901 T & gt;C polymorphism is associated with increased neuroblastoma risk in Chinese children
This study revealed that the MIR938 rs2505901 T>C polymorphism may be a potential risk factor for neuroblastoma in Chinese children. In the long term, conducting large and diverse sample studies from different ethnicities will indeed be crucial in determining the role of MIR938 polymorphisms in NB risk. By including individuals from various ethnic backgrounds, researchers can account for potential genetic variations that may exist between populations.PMID:37905791 | DOI:10.1042/BSR20231223 (Source: Bioscience Reports)
Source: Bioscience Reports - October 31, 2023 Category: Biomedical Science Authors: Susu Jiang Xiuhong Sun Xinxin Zhang Chunlei Zhou Haiyan Wu Jing He Wenhan Yang Source Type: research
MIR938 rs2505901 T & gt;C polymorphism is associated with increased neuroblastoma risk in Chinese children
This study revealed that the MIR938 rs2505901 T>C polymorphism may be a potential risk factor for neuroblastoma in Chinese children. In the long term, conducting large and diverse sample studies from different ethnicities will indeed be crucial in determining the role of MIR938 polymorphisms in NB risk. By including individuals from various ethnic backgrounds, researchers can account for potential genetic variations that may exist between populations.PMID:37905791 | DOI:10.1042/BSR20231223 (Source: Bioscience Reports)
Source: Bioscience Reports - October 31, 2023 Category: Biomedical Science Authors: Susu Jiang Xiuhong Sun Xinxin Zhang Chunlei Zhou Haiyan Wu Jing He Wenhan Yang Source Type: research
Therapeutic activity of green synthesized selenium nanoparticles from turmeric against cisplatin-induced oxido-inflammatory stress, and cell death in mice kidney
Biosci Rep. 2023 Oct 30:BSR20231130. doi: 10.1042/BSR20231130. Online ahead of print.ABSTRACTCisplatin (CDDP) is a commonly prescribed chemotherapeutic agent; however, its associated nephrotoxicity limits its clinical efficacy and sometimes requires discontinuation of its use. The existing study was designed to explore the reno-therapeutic efficacy of turmeric (Tur) alone or conjugated with selenium nanoparticles (Tur-SeNPs) against CDDP-mediated renal impairment in mice and the mechanisms underlying this effect. Mice were orally treated with Tur extract (200 mg/kg) or Tur-SeNPs (0.5 mg/kg) for 7 days after administration ...
Source: Bioscience Reports - October 30, 2023 Category: Biomedical Science Authors: Barakat M ALRashdi Roaya A Mohamed Amal H Mohamed Feryal A Samoul Mazen I Mohamed Mohsen M Moussa Saad M Alrashidi Bassel Dawod Ola A Habotta Ahmed Abdel Moneim Shimaa S Ramadan Source Type: research
Therapeutic activity of green synthesized selenium nanoparticles from turmeric against cisplatin-induced oxido-inflammatory stress, and cell death in mice kidney
Biosci Rep. 2023 Oct 30:BSR20231130. doi: 10.1042/BSR20231130. Online ahead of print.ABSTRACTCisplatin (CDDP) is a commonly prescribed chemotherapeutic agent; however, its associated nephrotoxicity limits its clinical efficacy and sometimes requires discontinuation of its use. The existing study was designed to explore the reno-therapeutic efficacy of turmeric (Tur) alone or conjugated with selenium nanoparticles (Tur-SeNPs) against CDDP-mediated renal impairment in mice and the mechanisms underlying this effect. Mice were orally treated with Tur extract (200 mg/kg) or Tur-SeNPs (0.5 mg/kg) for 7 days after administration ...
Source: Bioscience Reports - October 30, 2023 Category: Biomedical Science Authors: Barakat M ALRashdi Roaya A Mohamed Amal H Mohamed Feryal A Samoul Mazen I Mohamed Mohsen M Moussa Saad M Alrashidi Bassel Dawod Ola A Habotta Ahmed Abdel Moneim Shimaa S Ramadan Source Type: research
