Bioprocess and Biosystems Engineering This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Cyclic extraction of phosphate from soybean meal using immobilized Aspergillus oryzae SBS50 phytase
Bioprocess Biosyst Eng. 2023 Nov 14. doi: 10.1007/s00449-023-02943-9. Online ahead of print.ABSTRACTPhytase enzyme found in plants, animals, and microorganisms is mainly involved in catalyzing the systematic removal of a phosphate group from phytic acid. Enzyme immobilization is one of the cost-effective methods for the wide usage of enzymes in the industrial sector. This paper reports the covalent immobilization of phytase on glutaraldehyde-activated aluminum oxide beads. The immobilization yield, efficiency, and activation energy were found to be 47.8%, 71.5%, and 15.78 J/mol, respectively. The bound enzyme displayed a s...
Source: Bioprocess and Biosystems Engineering - November 14, 2023 Category: Biomedical Engineering Authors: Mallesh Gampa Sushil Nagar Kajal Kumari Ekta Tanwar Sakshi Goyal Vinod Kumar Bijender Singh Source Type: research

Engineered phage enzymes against drug-resistant pathogens: a review on advances and applications
Bioprocess Biosyst Eng. 2023 Nov 14. doi: 10.1007/s00449-023-02938-6. Online ahead of print.ABSTRACTIn recent decades, the expansion of multi and extensively drug-resistant (MDR and XDR) bacteria has reached an alarming rate, causing serious health concerns. Infections caused by drug-resistant bacteria have been associated with morbidity and mortality, making tackling bacterial resistance an urgent and unmet challenge that needs to be addressed properly. Endolysins are phage-encoded enzymes that can specifically degrade the bacterial cell wall and lead to bacterial death. There is remarkable evidence that corroborates the ...
Source: Bioprocess and Biosystems Engineering - November 14, 2023 Category: Biomedical Engineering Authors: Mohadeseh Hassannia Mahin Naderifar Shakiba Salamy Majid Reza Akbarizadeh Samane Mohebi Majid Taati Moghadam Source Type: research

Effect mechanism of micron-scale zero-valent iron enhanced pyrite-driven denitrification biofilter for nitrogen and phosphorus removal
This study aims to explore the effect mechanism of micron-scale zero-valent iron (mZVI) to improve nitrogen and phosphorus removal in a pyrite (FeS2)-driven denitrification biofilter (DNBF) for the secondary effluent treatment. Two similar DNBFs (DNBF-A with FeS2 as fillers and DNBF-B with the mixture mZVI and FeS2 as carrier) were developed. The results showed that NO3--N, total nitrogen (TN) and PO43--P removal efficiencies were up to 91.64%, 67.44% and 80.26% in DNBF-B, which were obviously higher than those of DNBF-A (with NO3--N, TN and PO43--P removal efficiencies of 38.39%, 44.89% and 53.02%, respectively). Kinetic ...
Source: Bioprocess and Biosystems Engineering - November 13, 2023 Category: Biomedical Engineering Authors: Xin Liu Xin Xin Wenyu Yang Xinyu Zhang Source Type: research

Synthesis and in vitro characteristics of biogenic-derived hydroxyapatite for bone remodeling applications
Bioprocess Biosyst Eng. 2023 Nov 12. doi: 10.1007/s00449-023-02940-y. Online ahead of print.ABSTRACTThe inorganic component of bone matrix, hydroxyapatite (HAp) (with formula Ca10(PO4)6(OH)2), can be obtained from inexpensive waste resources that serve as excellent calcium precursors. In the present study, HAp nano-powder was synthesized from eggshells (ES) and crab shells (CS) by wet chemical precipitation method. Also, a hybrid sample was considered which is a mixture of HAp nano-powder synthesized from eggshells (25%) and crab shells (75%) (EC). The presence of phosphate, carbonate, and hydroxyl groups in the synthesize...
Source: Bioprocess and Biosystems Engineering - November 12, 2023 Category: Biomedical Engineering Authors: B Ragini Sivakumar Kandhasamy Justin Packia Jacob Sekar Vijayakumar Source Type: research

Large-scale crystallization as an intermediate processing step in insulin downstream process: explored advantages and identified tool for process intensification
Bioprocess Biosyst Eng. 2023 Nov 8. doi: 10.1007/s00449-023-02931-z. Online ahead of print.ABSTRACTThe rising global prevalence of diabetes and increasing demand for insulin, calls for an increase in accessibility and affordability of insulin drugs through efficient and cost-effective manufacturing processes. Often downstream operations become manufacturing bottlenecks while processing a high volume of product. Thus, process integration and intensification play an important role in reducing process steps and time, volume reduction, and lower equipment footprints, which brings additional process efficiencies and lowers the ...
Source: Bioprocess and Biosystems Engineering - November 8, 2023 Category: Biomedical Engineering Authors: Partha Hazra Madhavan Buddha Chinnappa Reddy Indranil Gupta Source Type: research