Clinicopathological features of gastric hepatoid adenocarcinoma
Binit Sureka, Kalpana Bansal, Ankur AroraBiomedical Journal 2015 38(5):463-463 (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Binit SurekaKalpana BansalAnkur Arora Source Type: research

Questioning the impact of journal impact factor on research?
Tanuj Kanchan, Kewal KrishanBiomedical Journal 2015 38(5):462-462 (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Tanuj KanchanKewal Krishan Source Type: research

Medical record review for faculty promotion: A cohort analysis
Conclusions: The scores from external reviewers correlated more with routine scores than the scores from internal reviewers, suggesting that utilizing an external auditing system of medical records for the faculty promotion of attending physicians is quite feasible and balanced. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Chien-Da HuangChang-Chyi JenqLiang-Shiou OuAlvin C ChenShe-Hung ChanJing-Long HuangSan-Jou YehShih-Tseng Lee Source Type: research

Comparative evaluation of three mixed dentition analyses and formulation of regression equations for north Indian population: A cross-sectional study
Conclusion: All the methods evaluated in the study were found to be inaccurate and they overestimate the mesiodistal widths of permanent canine and premolars in North Indian population. Revised linear regression equations were derived using the data obtained from this population. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Suruchi JunejaNeeraj MahajanHarsimrit KaurKanika Gupta VermaManish SukhijaEenal Bhambri Source Type: research

Evaluating the impact of hippocampal sparing during whole brain radiotherapy on neurocognitive functions: A preliminary report of a prospective phase II study
Conclusions: Functional preservation by hippocampal sparing during WBRT could largely be achieved in this study, which also suggests that HA-WBRT should be a feasible technique preserving neurocognitive functions while maintaining intracranial control. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Shinn-Yn LinChi-Cheng YangYi-Ming WuChen-Kan TsengKuo-Chen WeiYi-Chuan ChuHsiang-Yao HsiehTung-Ho WuPing-Ching PaiPeng-Wei HsuChi-Cheng Chuang Source Type: research

Protein kinase Cη polymorphism and the susceptibility to ischemic stroke in the Taiwan population
Conclusion: The association between PRKCH 1425G/A and lacunar infarction was independent of traditional stroke risk factors. PRKCH 1425G/A in stroke susceptibility differed between infarction subtypes and age groups. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Yi-Chun ChenChi-Jui HuangPhoebe ChenYih-Ru WuShian-Sen ShieSien-Tsong ChenGuey-Jen Lee-ChenChiung-Mei Chen Source Type: research

CYP3A5 ∗ 3 genetic polymorphism is associated with childhood acute lymphoblastic leukemia risk: A meta-analysis
Conclusions: The current meta-analysis showed that there was association between CYP3A5 * 3 polymorphism and the altered risk of ALL in children, especially in Caucasian populations. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Li-Min MaHong-Chao LiuLin-Hai RuanYan-Ming Feng Source Type: research

Effect of ethephon on the liver in albino rats: A histomorphometric study
Conclusion: The plant growth regulator, insecticide, and fruit ripener, ethephon, caused inflammatory and degenerative changes in the liver with associated cholestasis, probably suggestive of toxic hepatitis. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Pooja BhadoriaMahindra NagarVeena BahriokeAjeet Singh Bhadoria Source Type: research

MCNPX simulation of proton dose distributions in a water phantom
Conclusions: Careful modelling of MCS is necessary when proton disequilibrium exists. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Chung-Chi LeeYun-Jing LeeShih-Kuan ChenBing-Hao ChiangChuan-Jong TungTsi-Chian Chao Source Type: research

Depth dose characteristics of proton beams within therapeutic energy range using the particle therapy simulation framework (PTSim) Monte Carlo technique
Conclusion: Detail depth dose characteristics for monoenergetic proton beams and beams with initial energy spreads within therapeutic energy ranges were reported. These data can serve as a good reference for a clinical practitioner in their daily practice. (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Siou-Yin CaiTsi-Chain ChaoMei-Jyun LinChuan-Jung TungChung-Chi Lee Source Type: research

Microdosimetric relative biological effectiveness of therapeutic proton beams
Chuan-Jong TungBiomedical Journal 2015 38(5):399-407When compared to photon beams, particle beams have distinct spatial distributions on the energy depositions in both the macroscopic and microscopic volumes. In a macroscopic volume, the absorbed dose distribution shows a rapid increase near the particle range, that is, Bragg peak, as particle penetrates deep inside the tissue. In a microscopic volume, individual particle deposits its energy along the particle track by producing localized ionizations through the formation of clusters. These highly localized clusters can induce complex types of deoxyribonucleic acid (DNA) d...
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Chuan-Jong Tung Source Type: research

What are the potential benefits of using proton therapy in Taiwanese cancer patients?
Wei-Heng Kao, Yi-Liang Shen, Ji-Hong HongBiomedical Journal 2015 38(5):391-398The potential benefits of proton therapy have been established in pediatric cancer, skull base tumor, uveal melanoma, and other types of cancers. Western and Asian countries, however, have differences in the pattern of cancer incidence; this leads to the difference in patient demographics for proton therapy. Furthermore, the advancement of the scanning beam technique in proton therapy greatly expands the capability of proton therapy in disease sites with great complexity. In this review, we focus on the cancers with high incidence in Taiwan, base...
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Wei-Heng KaoYi-Liang ShenJi-Hong Hong Source Type: research

Proton therapy
Chuan-Jong TungBiomedical Journal 2015 38(5):389-390 (Source: Biomedical Journal)
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Chuan-Jong Tung Source Type: research

Nitric oxide: Protein tyrosine phosphorylation and protein S-nitrosylation in cancer
Hugo P Monteiro, Paulo E Costa, Adriana K. C. A. Reis, Arnold SternBiomedical Journal 2015 38(5):380-388Cancer is a worldwide health problem leading to a high incidence of morbidity and mortality. Malignant transformation can occur by expression of oncogenes, over-expression and deregulated activation of proto-oncogenes, and inactivation of tumor suppressor genes. These cellular actions occur through stimulation of oncogenic signaling pathways. Nitric oxide (NO) can induce genetic changes in cells and its intracellular generation can lead to tumor formation and progression. It can also promote anti-tumor activities. The pr...
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Hugo P MonteiroPaulo E CostaAdriana K. C. A. ReisArnold Stern Source Type: research

Caveolae and cancer: A new mechanical perspective
Christophe Lamaze, Stéphanie TorrinoBiomedical Journal 2015 38(5):367-379Caveolae are small invaginations of the plasma membrane in cells. In addition to their classically described functions in cell signaling and membrane trafficking, it was recently shown that caveolae act also as plasma membrane sensors that respond immediately to acute mechanical stresses. Caveolin 1 (Cav1), the main component of caveolae, is a multifunctional scaffolding protein that can remodel the extracellular environment. Caveolae dysfunction, due to mutations in  caveolins, has been linked to several human diseases called...
Source: Biomedical Journal - October 9, 2015 Category: Biomedical Science Authors: Christophe LamazeStéphanie Torrino Source Type: research