Determination of flurbiprofen in rat plasma using ultra-high performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study
Biomed Chromatogr. 2023 Dec 10:e5780. doi: 10.1002/bmc.5780. Online ahead of print.ABSTRACTA rapid and sensitive ultra-high performance liquid chromatography-tandem mass spectrometry method was developed to determine flurbiprofen in rat plasma. A triple quadrupole tandem mass spectrometer equipped with an electrospray ionization (ESI) source was used in negative ion mode. Acetonitrile precipitation was selected to prepare samples. Flurbiprofen and internal standard flurbiprofen-d5 were analyzed on an Acquity UPLC BEH C18 column with the mobile phase consisting of acetonitrile and water, and a gradient procedure was used fo...
Source: Biomedical Chromatography : BMC - December 10, 2023 Category: Biomedical Science Authors: Xihong Zhao Chunjing Lv Hong Chen Feng Qin Xiumei Lu Source Type: research
Meeting Report on the 3rd Chinese American Society for Mass Spectrometry Conference-Advancing Biological and Pharmaceutical Mass Spectrometry
Biomed Chromatogr. 2023 Dec 10:e5795. doi: 10.1002/bmc.5795. Online ahead of print.ABSTRACTFollowing the highly successful Chinese American Society for Mass Spectrometry (CASMS) conferences in the previous 2 years, the 3rd CASMS Conference was held virtually on August 28-31, 2023, using the Gather.Town platform to bring together scientists in the MS field. The conference offered a 4-day agenda with a scientific program consisting of two plenary lectures, and 14 parallel symposia in which a total of 70 speakers presented technological innovations and their applications in proteomics and biological MS and metabo-lipidomics a...
Source: Biomedical Chromatography : BMC - December 10, 2023 Category: Biomedical Science Authors: Hao Chen Yunlin Fu Mei Han Xianlin Han Ling Hao Tao Huan Lan Huang Ming Huang Qin Ji Tao Jiang Yong Jiang Liang Li Lingjun Li Xiaorong Liang Mamie Lih Yanping Lin Xiaowen Liu Tao Liu Yansheng Liu Shuguang Ma Junmin Peng Yue A Qi Jun Qu Wilson Shou Liangli Source Type: research
A novel liquid chromatography with quadrupole time-of-flight-tandem mass spectroscopy method for ultra-trace level identification and quantification of the genotoxic impurity 2,6-diamino-5-nitropyrimidin-4(3H)-one in valganciclovir hydrochloride
Biomed Chromatogr. 2023 Dec 10:e5805. doi: 10.1002/bmc.5805. Online ahead of print.ABSTRACTIn the present study, the main objective is to develop an analytical method for ultra-trace level measurement of 2,6-diamino-5-nitropyrimidin-4(3H)-one (DMNP) in valganciclovir hydrochloride (VAL) using liquid chromatography-quadrupole time-of-flight-tandem mass spectroscopy (LC-QTOF-MS/MS). In the early stages of guanine synthesis, DMNP is formed, and guanine is known to be the key starting material for the synthesis of VAL. Taking into consideration DMNP potential genotoxicity, this analytical method has been developed. This method...
Source: Biomedical Chromatography : BMC - December 10, 2023 Category: Biomedical Science Authors: Shaik Mahammad Ali Manchuri Krishna Moorthy Nayakanti Devanna Source Type: research
Residue analysis and dietary risk assessment of abamectin in fresh corn, bitter melon, and Fritillaria
Biomed Chromatogr. 2023 Dec 4:e5779. doi: 10.1002/bmc.5779. Online ahead of print.ABSTRACTTo clarify the residue behavior and possible dietary risk of abamectin in fresh corn, bitter melon, and Fritillaria, a method was developed for the simultaneous determination of abamectin residues in fresh corn, bitter melon, and Fritillaria by QuEChERS (quick, easy, cheap, effective, rugged, safe) ultra-performance liquid chromatography-tandem mass spectrometry. The mean recovery of abamectin in fresh corn, bitter melon, and Fritillaria was 86.48%-107.80%, and the relative standard deviation was 2.07%-10.12%. The detection rates of a...
Source: Biomedical Chromatography : BMC - December 5, 2023 Category: Biomedical Science Authors: Xiaorong Luo Changpeng Zhang Yuqin Luo Nan Fang Xiangyun Wang Hongmei He Jinhua Jiang Yuting Chen Zhendong Cai Xueping Zhao Source Type: research
Residue analysis and dietary risk assessment of abamectin in fresh corn, bitter melon, and Fritillaria
Biomed Chromatogr. 2023 Dec 4:e5779. doi: 10.1002/bmc.5779. Online ahead of print.ABSTRACTTo clarify the residue behavior and possible dietary risk of abamectin in fresh corn, bitter melon, and Fritillaria, a method was developed for the simultaneous determination of abamectin residues in fresh corn, bitter melon, and Fritillaria by QuEChERS (quick, easy, cheap, effective, rugged, safe) ultra-performance liquid chromatography-tandem mass spectrometry. The mean recovery of abamectin in fresh corn, bitter melon, and Fritillaria was 86.48%-107.80%, and the relative standard deviation was 2.07%-10.12%. The detection rates of a...
Source: Biomedical Chromatography : BMC - December 5, 2023 Category: Biomedical Science Authors: Xiaorong Luo Changpeng Zhang Yuqin Luo Nan Fang Xiangyun Wang Hongmei He Jinhua Jiang Yuting Chen Zhendong Cai Xueping Zhao Source Type: research
Residue analysis and dietary risk assessment of abamectin in fresh corn, bitter melon, and Fritillaria
Biomed Chromatogr. 2023 Dec 4:e5779. doi: 10.1002/bmc.5779. Online ahead of print.ABSTRACTTo clarify the residue behavior and possible dietary risk of abamectin in fresh corn, bitter melon, and Fritillaria, a method was developed for the simultaneous determination of abamectin residues in fresh corn, bitter melon, and Fritillaria by QuEChERS (quick, easy, cheap, effective, rugged, safe) ultra-performance liquid chromatography-tandem mass spectrometry. The mean recovery of abamectin in fresh corn, bitter melon, and Fritillaria was 86.48%-107.80%, and the relative standard deviation was 2.07%-10.12%. The detection rates of a...
Source: Biomedical Chromatography : BMC - December 5, 2023 Category: Biomedical Science Authors: Xiaorong Luo Changpeng Zhang Yuqin Luo Nan Fang Xiangyun Wang Hongmei He Jinhua Jiang Yuting Chen Zhendong Cai Xueping Zhao Source Type: research
Residue analysis and dietary risk assessment of abamectin in fresh corn, bitter melon, and Fritillaria
Biomed Chromatogr. 2023 Dec 4:e5779. doi: 10.1002/bmc.5779. Online ahead of print.ABSTRACTTo clarify the residue behavior and possible dietary risk of abamectin in fresh corn, bitter melon, and Fritillaria, a method was developed for the simultaneous determination of abamectin residues in fresh corn, bitter melon, and Fritillaria by QuEChERS (quick, easy, cheap, effective, rugged, safe) ultra-performance liquid chromatography-tandem mass spectrometry. The mean recovery of abamectin in fresh corn, bitter melon, and Fritillaria was 86.48%-107.80%, and the relative standard deviation was 2.07%-10.12%. The detection rates of a...
Source: Biomedical Chromatography : BMC - December 5, 2023 Category: Biomedical Science Authors: Xiaorong Luo Changpeng Zhang Yuqin Luo Nan Fang Xiangyun Wang Hongmei He Jinhua Jiang Yuting Chen Zhendong Cai Xueping Zhao Source Type: research
Prediction and analysis of quality markers for Chuantieling gel patches based on HPLC fingerprinting and network pharmacology
This study provides insight into the complex multicomponent composition of CGP, and the predictive analysis through network pharmacology sets the stage for uncovering the mechanisms responsible for the therapeutic effects of CGP.PMID:38048642 | DOI:10.1002/bmc.5773 (Source: Biomedical Chromatography : BMC)
Source: Biomedical Chromatography : BMC - December 4, 2023 Category: Biomedical Science Authors: Lixin Du Huiling Lu Yifei Xiao Zhihua Guo Ya Li Source Type: research
Chromatographic assessment of biodiesel production from Peganum harmala seed oil using environmentally benign nano-catalysts
Biomed Chromatogr. 2023 Dec 4:e5794. doi: 10.1002/bmc.5794. Online ahead of print.ABSTRACTThis work gives a comprehensive chromatographic assessment of biodiesel generation from plant seed oil using ecologically friendly nano-catalysts. Researchers all over the world are actively looking for new ways to satisfy the urgent need for clean and renewable energy sources. The resultant biodiesel was fully characterized utilizing modern techniques like scanning electron microscopy, energy diffraction X-ray and X-ray diffraction. The biodiesel gas chromatography/mass spectrometry analysis revealed four significant peaks of fatty a...
Source: Biomedical Chromatography : BMC - December 4, 2023 Category: Biomedical Science Authors: Eman Alhomaidi Maha Aljabri Salam S Alsharari Amani Alsam Source Type: research
Prediction and analysis of quality markers for Chuantieling gel patches based on HPLC fingerprinting and network pharmacology
This study provides insight into the complex multicomponent composition of CGP, and the predictive analysis through network pharmacology sets the stage for uncovering the mechanisms responsible for the therapeutic effects of CGP.PMID:38048642 | DOI:10.1002/bmc.5773 (Source: Biomedical Chromatography : BMC)
Source: Biomedical Chromatography : BMC - December 4, 2023 Category: Biomedical Science Authors: Lixin Du Huiling Lu Yifei Xiao Zhihua Guo Ya Li Source Type: research
Chromatographic assessment of biodiesel production from Peganum harmala seed oil using environmentally benign nano-catalysts
Biomed Chromatogr. 2023 Dec 4:e5794. doi: 10.1002/bmc.5794. Online ahead of print.ABSTRACTThis work gives a comprehensive chromatographic assessment of biodiesel generation from plant seed oil using ecologically friendly nano-catalysts. Researchers all over the world are actively looking for new ways to satisfy the urgent need for clean and renewable energy sources. The resultant biodiesel was fully characterized utilizing modern techniques like scanning electron microscopy, energy diffraction X-ray and X-ray diffraction. The biodiesel gas chromatography/mass spectrometry analysis revealed four significant peaks of fatty a...
Source: Biomedical Chromatography : BMC - December 4, 2023 Category: Biomedical Science Authors: Eman Alhomaidi Maha Aljabri Salam S Alsharari Amani Alsam Source Type: research
Rapid haemoglobin A and S quantification using Tosoh HLC-723G8 in variant mode for patients with sickle cell disease
Biomed Chromatogr. 2023 Dec 1:e5799. doi: 10.1002/bmc.5799. Online ahead of print.ABSTRACTThe management of life-threatening complications in patients with sickle cell disease (SCD) requires an accurate and reproducible quantification of haemoglobin A (HbA) and S (HbS) with a short turnaround time and 24-7 availability. We propose a novel method for quantifying HbA and HbS using the glycated haemoglobin (HbA1c) assay on a Tosoh HLC-723G8 (G8) analyser in variant mode. HbA and HbS results obtained using our method highly correlated with results obtained using a reference method (r > 0.99 for 124 samples of patients with ...
Source: Biomedical Chromatography : BMC - December 2, 2023 Category: Biomedical Science Authors: Julien Fadel Juliette Noyelle Mathieu Maingon Chadi Homedan Xavier Dieu Juan Manuel Chao de la Barca Pascal Reynier Coralie Mallebranche Jean-Fran çois Brasme Delphine Mirebeau-Prunier Corentin Orvain Floris Chabrun Source Type: research
Rapid haemoglobin A and S quantification using Tosoh HLC-723G8 in variant mode for patients with sickle cell disease
Biomed Chromatogr. 2023 Dec 1:e5799. doi: 10.1002/bmc.5799. Online ahead of print.ABSTRACTThe management of life-threatening complications in patients with sickle cell disease (SCD) requires an accurate and reproducible quantification of haemoglobin A (HbA) and S (HbS) with a short turnaround time and 24-7 availability. We propose a novel method for quantifying HbA and HbS using the glycated haemoglobin (HbA1c) assay on a Tosoh HLC-723G8 (G8) analyser in variant mode. HbA and HbS results obtained using our method highly correlated with results obtained using a reference method (r > 0.99 for 124 samples of patients with ...
Source: Biomedical Chromatography : BMC - December 2, 2023 Category: Biomedical Science Authors: Julien Fadel Juliette Noyelle Mathieu Maingon Chadi Homedan Xavier Dieu Juan Manuel Chao de la Barca Pascal Reynier Coralie Mallebranche Jean-Fran çois Brasme Delphine Mirebeau-Prunier Corentin Orvain Floris Chabrun Source Type: research
Rapid haemoglobin A and S quantification using Tosoh HLC-723G8 in variant mode for patients with sickle cell disease
Biomed Chromatogr. 2023 Dec 1:e5799. doi: 10.1002/bmc.5799. Online ahead of print.ABSTRACTThe management of life-threatening complications in patients with sickle cell disease (SCD) requires an accurate and reproducible quantification of haemoglobin A (HbA) and S (HbS) with a short turnaround time and 24-7 availability. We propose a novel method for quantifying HbA and HbS using the glycated haemoglobin (HbA1c) assay on a Tosoh HLC-723G8 (G8) analyser in variant mode. HbA and HbS results obtained using our method highly correlated with results obtained using a reference method (r > 0.99 for 124 samples of patients with ...
Source: Biomedical Chromatography : BMC - December 2, 2023 Category: Biomedical Science Authors: Julien Fadel Juliette Noyelle Mathieu Maingon Chadi Homedan Xavier Dieu Juan Manuel Chao de la Barca Pascal Reynier Coralie Mallebranche Jean-Fran çois Brasme Delphine Mirebeau-Prunier Corentin Orvain Floris Chabrun Source Type: research
An ultrahigh-performance liquid chromatography-tandem mass spectrometry method for quantification of methotrexate and 7-hydroxy-methotrexate and application for therapeutic drug monitoring in patients with central nervous system lymphoma
Biomed Chromatogr. 2023 Dec 1:e5789. doi: 10.1002/bmc.5789. Online ahead of print.ABSTRACTA method using ultrahigh-performance liquid chromatography-tandem mass spectrometry was developed, validated, and applied to simultaneously determine plasma methotrexate (MTX) and 7-hydroxy-methotrexate (7-OH-MTX) in 117 patients with central nervous system (CNS) lymphoma. The ion transitions utilized were m/z 455.2 > 308.2 for MTX and m/z 471.2 > 324.1 for 7-OH-MTX. Samples were prepared through protein precipitation using methanol. Chromatographic separation was achieved within 3.0 min on a CMS9030 column (Ruixi, 2.1 × 50 mm,...
Source: Biomedical Chromatography : BMC - December 1, 2023 Category: Biomedical Science Authors: Jiping Huo Bo Zhang Dongjie Zhang Bin Zhu Zhigang Zhao Shenghui Mei Source Type: research
