Genome-Wide Screens Identify Genes Responsible for Intrinsic Boric Acid Resistance in Escherichia coli
This study demonstrates that intrinsic BA resistance is the result of various mechanisms acting together. Additionally, we identified eighteen out of ninety-two mutant strains (Delta_aceF, aroK, cheZ, dinJ, galS, garP, glxK, nohA, talB, torR, trmU, trpR, yddE, yfeS, ygaV, ylaC, yoaC, yohN) that exhibited sensitivity using other methods. To increase sensitivity to BA, we constructed double and triple knockout mutants of the selected sensitive mutants. In certain instances, engineered double and triple mutants exhibited significantly amplified effects. Overall, our analysis of these findings offers further understanding of t...
Source: Biological Trace Element Research - March 11, 2024 Category: Biology Authors: Bekir Çöl Merve Sezer K ürkçü Esra Di Bek Source Type: research

Monitoring of Essential and Toxic Elements in Multivitamin/Mineral Effervescent Tablet Supplements and Safety Assessment
Biol Trace Elem Res. 2024 Mar 9. doi: 10.1007/s12011-024-04138-z. Online ahead of print.ABSTRACTMultivitamin/mineral (MVM) supplements are the most commonly utilized dietary supplements by many populations. However, there is a severe concern about their adverse effects due to elemental impurities. In the present study, it was aimed to determine the levels of 11 elemental impurities (Cd, Pb, As, Hg, Co, V, Ni, Se, Mo, Cu, and Cr) by inductively coupled plasma-mass spectrometry (ICP-MS) and evaluate the human health risk associated with the consumption of 33 MVM effervescent tablet supplements available in Turkey. The precis...
Source: Biological Trace Element Research - March 9, 2024 Category: Biology Authors: İrem Uslu Orkun Alp Bensu Karahalil Source Type: research

Monitoring of Essential and Toxic Elements in Multivitamin/Mineral Effervescent Tablet Supplements and Safety Assessment
Biol Trace Elem Res. 2024 Mar 9. doi: 10.1007/s12011-024-04138-z. Online ahead of print.ABSTRACTMultivitamin/mineral (MVM) supplements are the most commonly utilized dietary supplements by many populations. However, there is a severe concern about their adverse effects due to elemental impurities. In the present study, it was aimed to determine the levels of 11 elemental impurities (Cd, Pb, As, Hg, Co, V, Ni, Se, Mo, Cu, and Cr) by inductively coupled plasma-mass spectrometry (ICP-MS) and evaluate the human health risk associated with the consumption of 33 MVM effervescent tablet supplements available in Turkey. The precis...
Source: Biological Trace Element Research - March 9, 2024 Category: Biology Authors: İrem Uslu Orkun Alp Bensu Karahalil Source Type: research

Monitoring of Essential and Toxic Elements in Multivitamin/Mineral Effervescent Tablet Supplements and Safety Assessment
Biol Trace Elem Res. 2024 Mar 9. doi: 10.1007/s12011-024-04138-z. Online ahead of print.ABSTRACTMultivitamin/mineral (MVM) supplements are the most commonly utilized dietary supplements by many populations. However, there is a severe concern about their adverse effects due to elemental impurities. In the present study, it was aimed to determine the levels of 11 elemental impurities (Cd, Pb, As, Hg, Co, V, Ni, Se, Mo, Cu, and Cr) by inductively coupled plasma-mass spectrometry (ICP-MS) and evaluate the human health risk associated with the consumption of 33 MVM effervescent tablet supplements available in Turkey. The precis...
Source: Biological Trace Element Research - March 9, 2024 Category: Biology Authors: İrem Uslu Orkun Alp Bensu Karahalil Source Type: research

Heavy Metals in Common Fishes Consumed in Dhaka, a Megacity of Asia: A Probabilistic Carcinogenic and Non-Carcinogenic Health Hazard
In this study, six commonly consumed fish species namely Hilsha (Tenualosa ilisha), Kachki (Corica soborna), Punti (Puntitus ticto), Taki (Channa punctatus), Meni (Nandus nandus), and Tengra (Mystus tengara) were analyzed for arsenic (As), cadmium (Cd), lead (Pb), zinc (Zn), copper (Cu), chromium (Cr), manganese (Mn), and nickel (Ni), by inductively coupled plasma mass spectrometry. The fish samples were collected from wholesale markets in Dhaka city, the main business hub of Bangladesh where the fishes converged from countrywide and are redistributed to the whole city. The metal concentration varied among the studied fish...
Source: Biological Trace Element Research - March 8, 2024 Category: Biology Authors: Nazma Shaheen Marjia Sultana Towhid Hasan Ishrat Nourin Khan Nafis Md Irfan Md Kawser Ahmed Source Type: research

Immunomodulatory Effects of Vitamin D and Zinc on Viral Infection
Biol Trace Elem Res. 2024 Mar 7. doi: 10.1007/s12011-024-04139-y. Online ahead of print.ABSTRACTSeveral nutrients are crucial in enhancing the immune system and preserving the structural integrity of bodily tissue barriers. Vitamin D (VD) and zinc (Zn) have received considerable interest due to their immunomodulatory properties and ability to enhance the body's immune defenses. Due to their antiviral, anti-inflammatory, antioxidative, and immunomodulatory properties, the two nutritional powerhouses VD and Zn are crucial for innate and adaptive immunity. As observed with COVID-19, deficiencies in these micronutrients impair...
Source: Biological Trace Element Research - March 7, 2024 Category: Biology Authors: Muhammad Rizwan Ke Cheng Yang Gang Yuntao Hou Chunfang Wang Source Type: research

Immunomodulatory Effects of Vitamin D and Zinc on Viral Infection
Biol Trace Elem Res. 2024 Mar 7. doi: 10.1007/s12011-024-04139-y. Online ahead of print.ABSTRACTSeveral nutrients are crucial in enhancing the immune system and preserving the structural integrity of bodily tissue barriers. Vitamin D (VD) and zinc (Zn) have received considerable interest due to their immunomodulatory properties and ability to enhance the body's immune defenses. Due to their antiviral, anti-inflammatory, antioxidative, and immunomodulatory properties, the two nutritional powerhouses VD and Zn are crucial for innate and adaptive immunity. As observed with COVID-19, deficiencies in these micronutrients impair...
Source: Biological Trace Element Research - March 7, 2024 Category: Biology Authors: Muhammad Rizwan Ke Cheng Yang Gang Yuntao Hou Chunfang Wang Source Type: research

Conch Shell (Turbinella pyrum) Powder: A Potential Marine Biological Source of Calcium and Some Trace Minerals for Growing Crossbred Calves
Biol Trace Elem Res. 2024 Mar 5. doi: 10.1007/s12011-024-04104-9. Online ahead of print.ABSTRACTThe present study was conducted to evaluate the effect of feeding conch shell (Turbinella pyrum) powder (either fresh or calcined) as a marine organic source of calcium (Ca) supplemented in the diet of crossbred calves on voluntary intake, growth performance, and blood biochemistry in growing crossbred Jersey calves. A growth trial of 90 days was conducted on 15 Jersey crossbred female calves (Av. weight, 70.68 ± 2.90 kg; Av. age, 197.73 ± 12.40 days), equally divided into three groups of 5 animals each, i.e., control (T0), tr...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Jagruti Bhagat Tapas Kumar Dutta Anupam Chatterjee Sushil Kumar Yadav Asif Mohammad Saroj Rai Source Type: research

Toxicity and Hepatoprotective Effects of ZnO Nanoparticles on Normal and High-Fat Diet-Fed Rat Livers: Mechanism of Action
Biol Trace Elem Res. 2024 Mar 5. doi: 10.1007/s12011-024-04108-5. Online ahead of print.ABSTRACTThis experiment aimed to evaluate the beneficial and toxic properties of synthetic zinc oxide nanoparticles (ZnO NPs) on the liver of normal and high-fat diet (HFD) fed-rats. The ZnO NPs were synthesized and, its characterizations were determined by different techniques. Effect of ZnO NP on cell viability, liver enzymes and lipid accumulation were measured in HepG2 cells after 24 h. After that, rats orally received various dosages of ZnO NPs for period of 4 weeks. Toxicity tests were done to determine the appropriate dose. In th...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Fatemeh Mirzaei Ebrahim Abbasi Amir Mirzaei Nashmin Fayazi Hosseini Nima Naseri Iraj Khodadadi Cyrus Jalili Nesrine Majdoub Source Type: research

Association of Plasma Metal Levels with Outcomes of Assisted Reproduction in Polycystic Ovary Syndrome
The objective of this study is to explore the correlation of metal levels with assisted reproductive technology (ART) outcomes in polycystic ovary syndrome (PCOS) patients. The individuals were recruited who met the research criteria, only tubal factor or male infertility served as the control group (n = 40) and patient group was PCOS patients (n = 35). Individuals (n = 75) were divided into PCOS group (n = 35) and control group (n = 40). The normal body mass index (BMI) group (control) includes women with BMI < 25 kg/m2 in PCOS group (n = 24) and control group (n = 33), and BMI ≥ 25 kg/m2 in PCOS group (n = 11) and c...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Dan Yin Rui Mao Die Wang Ping Yu Cuilan Zhou Jun Liu Suyun Li Yulin Nie Hongqing Liao Cuiying Peng Source Type: research

Foraging Activity of Honey Bees (Apis mellifera L., 1758) and Exposure to Cadmium: a Review
Biol Trace Elem Res. 2024 Mar 5. doi: 10.1007/s12011-024-04118-3. Online ahead of print.ABSTRACTHoney bees are commonly exposed to a broad spectrum of xenobiotics, including heavy metals. Heavy metal toxicity is of concern in the context of global pollinator declines, especially since honey bees seem to be particularly susceptible to xenobiotics in general. Here we summarize current knowledge on the interplay between cadmium, one of the most toxic and mobile elements in the environment, and honey bees, the primary managed pollinator species worldwide. Overall, cadmium pollution has been shown to be ubiquitous, affecting in...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Stephane Knoll Maria Grazia Cappai Source Type: research

Analysis of Elements and Effects of Common Disinfectants in Common Salad Vegetables
Biol Trace Elem Res. 2024 Mar 6. doi: 10.1007/s12011-024-04135-2. Online ahead of print.ABSTRACTIn this research, firstly, the effect of some cleaners or disinfectants (including washing with water, blue ozone (O3, 0.5ppm), blue benzalkonium chloride (BAC, 120ppm), the combination of two treatments (O3 + BAC)) on the population of two pathogens plant was evaluated, secondly 14 elements (Ca (calcium), magnesium (magnesium), As (arsenic), Al (aluminum), mercury (mercury), Se (selenium), cadmium (cadmium), K (potassium), Iron (Fe), nickel (Ni), zinc (Zn), sodium (Na), manganese (Mn) and lead (Pb)) were evaluated in romaine le...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Fahimeh Tooryan Mojtaba Moazzen Issa Mohammadpour Fard Narges Anvar Majid Arabameri Nabi Shariatifar Pegah Kargarghomsheh Source Type: research

Conch Shell (Turbinella pyrum) Powder: A Potential Marine Biological Source of Calcium and Some Trace Minerals for Growing Crossbred Calves
Biol Trace Elem Res. 2024 Mar 5. doi: 10.1007/s12011-024-04104-9. Online ahead of print.ABSTRACTThe present study was conducted to evaluate the effect of feeding conch shell (Turbinella pyrum) powder (either fresh or calcined) as a marine organic source of calcium (Ca) supplemented in the diet of crossbred calves on voluntary intake, growth performance, and blood biochemistry in growing crossbred Jersey calves. A growth trial of 90 days was conducted on 15 Jersey crossbred female calves (Av. weight, 70.68 ± 2.90 kg; Av. age, 197.73 ± 12.40 days), equally divided into three groups of 5 animals each, i.e., control (T0), tr...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Jagruti Bhagat Tapas Kumar Dutta Anupam Chatterjee Sushil Kumar Yadav Asif Mohammad Saroj Rai Source Type: research

Toxicity and Hepatoprotective Effects of ZnO Nanoparticles on Normal and High-Fat Diet-Fed Rat Livers: Mechanism of Action
Biol Trace Elem Res. 2024 Mar 5. doi: 10.1007/s12011-024-04108-5. Online ahead of print.ABSTRACTThis experiment aimed to evaluate the beneficial and toxic properties of synthetic zinc oxide nanoparticles (ZnO NPs) on the liver of normal and high-fat diet (HFD) fed-rats. The ZnO NPs were synthesized and, its characterizations were determined by different techniques. Effect of ZnO NP on cell viability, liver enzymes and lipid accumulation were measured in HepG2 cells after 24 h. After that, rats orally received various dosages of ZnO NPs for period of 4 weeks. Toxicity tests were done to determine the appropriate dose. In th...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Fatemeh Mirzaei Ebrahim Abbasi Amir Mirzaei Nashmin Fayazi Hosseini Nima Naseri Iraj Khodadadi Cyrus Jalili Nesrine Majdoub Source Type: research

Association of Plasma Metal Levels with Outcomes of Assisted Reproduction in Polycystic Ovary Syndrome
The objective of this study is to explore the correlation of metal levels with assisted reproductive technology (ART) outcomes in polycystic ovary syndrome (PCOS) patients. The individuals were recruited who met the research criteria, only tubal factor or male infertility served as the control group (n = 40) and patient group was PCOS patients (n = 35). Individuals (n = 75) were divided into PCOS group (n = 35) and control group (n = 40). The normal body mass index (BMI) group (control) includes women with BMI < 25 kg/m2 in PCOS group (n = 24) and control group (n = 33), and BMI ≥ 25 kg/m2 in PCOS group (n = 11) and c...
Source: Biological Trace Element Research - March 5, 2024 Category: Biology Authors: Dan Yin Rui Mao Die Wang Ping Yu Cuilan Zhou Jun Liu Suyun Li Yulin Nie Hongqing Liao Cuiying Peng Source Type: research