Sodium Selenite Ameliorates Silver Nanoparticles Induced Vascular Endothelial Cytotoxic Injury by Antioxidative Properties and Suppressing Inflammation Through Activating the Nrf2 Signaling Pathway
Biol Trace Elem Res. 2023 Dec 27. doi: 10.1007/s12011-023-04014-2. Online ahead of print.ABSTRACTSilver nanoparticles (AgNP) are the dominant nanomaterials in commercial products and the medical field, but the widespread occurrence of AgNP has become a global threat to human health. Growing studies indicate that AgNP exposure can induce vascular endothelial toxicity by excessive oxidative stress and inflammation, which is closely related to cardiovascular disease (CVD), but the potential intrinsic mechanism remains poorly elucidated. Thus, it has been crucial to control the toxicological effects of AgNP in order to improve...
Source: Biological Trace Element Research - December 27, 2023 Category: Biology Authors: Yunyun Ma Lei Wang Jing He Xueping Ma Jingjing Wang Ru Yan Wanrui Ma Huiyan Ma Yajuan Liu Hongqian Sun Xiaoxia Zhang Shaobin Jia Hao Wang Source Type: research

Spice-Induced Metal Contamination and Microbiological Risk Assessment of Instant Noodles Prepared for Human Consumption
Biol Trace Elem Res. 2023 Dec 27. doi: 10.1007/s12011-023-04018-y. Online ahead of print.ABSTRACTWith the rising worries of potential metal contamination in cooked noodles, this study aimed at unravelling, for the first time, the possible source of metal contamination in cooked noodles. Noodles cooked with full spices (CWFS), cooked with half spices (CWHS), cooked with quarter spices (CWQS), and cooked with no spices (CWNS: control) and their spices were analysed for metals using inductively coupled plasma-atomic emission spectrometry. The microbiological quality of the noodles was also evaluated. Metal concentrations in c...
Source: Biological Trace Element Research - December 27, 2023 Category: Biology Authors: Akaninyene Joseph Uwem Edet Edet Asanga Favor Akpakpan Udoeyop Bassey Ini Ubi Glory Bebia Ajoke F I Akindele Regina Odu Francisca Nwaokorie Source Type: research

Sodium Selenite Ameliorates Silver Nanoparticles Induced Vascular Endothelial Cytotoxic Injury by Antioxidative Properties and Suppressing Inflammation Through Activating the Nrf2 Signaling Pathway
Biol Trace Elem Res. 2023 Dec 27. doi: 10.1007/s12011-023-04014-2. Online ahead of print.ABSTRACTSilver nanoparticles (AgNP) are the dominant nanomaterials in commercial products and the medical field, but the widespread occurrence of AgNP has become a global threat to human health. Growing studies indicate that AgNP exposure can induce vascular endothelial toxicity by excessive oxidative stress and inflammation, which is closely related to cardiovascular disease (CVD), but the potential intrinsic mechanism remains poorly elucidated. Thus, it has been crucial to control the toxicological effects of AgNP in order to improve...
Source: Biological Trace Element Research - December 27, 2023 Category: Biology Authors: Yunyun Ma Lei Wang Jing He Xueping Ma Jingjing Wang Ru Yan Wanrui Ma Huiyan Ma Yajuan Liu Hongqian Sun Xiaoxia Zhang Shaobin Jia Hao Wang Source Type: research

Spice-Induced Metal Contamination and Microbiological Risk Assessment of Instant Noodles Prepared for Human Consumption
Biol Trace Elem Res. 2023 Dec 27. doi: 10.1007/s12011-023-04018-y. Online ahead of print.ABSTRACTWith the rising worries of potential metal contamination in cooked noodles, this study aimed at unravelling, for the first time, the possible source of metal contamination in cooked noodles. Noodles cooked with full spices (CWFS), cooked with half spices (CWHS), cooked with quarter spices (CWQS), and cooked with no spices (CWNS: control) and their spices were analysed for metals using inductively coupled plasma-atomic emission spectrometry. The microbiological quality of the noodles was also evaluated. Metal concentrations in c...
Source: Biological Trace Element Research - December 27, 2023 Category: Biology Authors: Akaninyene Joseph Uwem Edet Edet Asanga Favor Akpakpan Udoeyop Bassey Ini Ubi Glory Bebia Ajoke F I Akindele Regina Odu Francisca Nwaokorie Source Type: research

Ecological and Health Risk Assessment of Heavy Metals Bioaccumulation in Ganges Fish Near Varanasi, India
Biol Trace Elem Res. 2023 Dec 26. doi: 10.1007/s12011-023-04020-4. Online ahead of print.ABSTRACTHeavy metal contamination in river Ganga is one of the factors for deterioration in its water quality and also adds to human health risks. We designed our study to achieve a holistic approach by not only estimating the concentration of heavy metals (lead, manganese, chromium, and cadmium) in the river water at different sites based on human anthropogenic activities but also in the fishes residing in the same sites that are collected for human consumption on daily basis. We found that Ganga River in Varanasi is highly loaded wit...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Bhargawi Mishra Geeta J Gautam Rajnish Kumar Chaturvedi Nasreen Ghazi Ansari Vijaya Nath Mishra Source Type: research

Selenium Nanoparticles Ameliorate Adverse Impacts of Aflatoxin in Nile Tilapia with Special Reference to Streptococcus agalactiae Infection
Biol Trace Elem Res. 2023 Dec 26. doi: 10.1007/s12011-023-04031-1. Online ahead of print.ABSTRACTAflatoxin B1 (AFB1) is a plant-origin toxin that could induce oxidative stress in fish. The micromineral selenium (Se) possesses well-documented antioxidant properties. To assess the ameliorative effects of SeNPs (1 mg/kg fish feed) on oxidative stress induced by AFB1 (500 μg/kg fish feed), Nile tilapia (32.2±1.7 g body weight) were distributed randomly and even in six groups for 8-week feeding trial. Live enzymes, AST, ALT, and ALP levels were increased in the serum of fish fed AFB1-contaminated diet, and the addition of SeN...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Ahmed H Sherif Mohsen A Zommara Source Type: research

The Association between Magnesium Depletion Score and Hypertension in US Adults: Evidence from the National Health and Nutrition Examination Survey (2007-2018)
This study aims to explore the link between MDS and hypertension (HTN) using the National Health and Nutrition Examination Survey (NHANES) data. A total of 9708 participants from NHANES (2007-2018) were enrolled to investigate MDS's connection with HTN. HTN was defined based on clinical guidelines. MDS classification (low, 0-1; middle, 2; high, 3-5) relied on alcohol consumption, diuretic use, proton-pump inhibitor (PPI) usage, and kidney disease. Multivariable logistic regression assessed MDS-HTN association. Subsequent analyses included interaction tests, subgroups, and sensitivity analysis. Each unit increase in MDS cor...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Mo-Yao Tan Chao-Yue Mo Qian Zhao Source Type: research

Antibiotic Residues and Zinc Concentrations in the Livers and Kidneys of Portuguese Piglets-Relationship to Antibiotic and Zinc Resistance in Intestinal Escherichia coli
This study aims to determine antibiotic residues and Zn concentration in piglets' livers (n = 56) and kidneys (n = 60); and to examine the correlation between the use of Zn and antibiotics, and resistance to Zn and antibiotics of Escherichia coli isolated from piglets' faeces (n = 60). Samples were collected from randomly selected healthy piglets (n = 60); antibiotic residues were quantified by ultra-high-performance-liquid-chromatography time-of-flight mass spectrometry (UHPLC-ToF-MS); Zn was quantified using flame atomic absorption spectrometry (FAAS); microbiological methods were used for E. coli isolation, antibiotic s...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Olga Cardoso Gabriela Assis Maria M Donato Sara Carolina Henriques Andreia Freitas Fernando Ramos Source Type: research

Arsenic Exposure Induces Neuro-immune Toxicity in the Cerebral Cortex and the Hippocampus via Neuroglia and NLRP3 Inflammasome Activation in C57BL/6 Mice
This study aimed to examine the immuntoxic effects of arsenic in the nervous system. Our results showed that arsenic increased corticocerebral and hippocampal weights (p < 0.05). Morris water maze tests revealed that arsenic significantly increased the time spent in latency to platform on the fourth day in 50 mg/L arsenic exposure and the fifth day in 25 and 50 mg/L arsenic exposure, as well as reduced the path length in target quadrant, time spent in target quadrant, and crossing times of the platform (p < 0.05). Hematoxylin-eosin staining showed that the vacuolated degeneration and pyknosis was found in the cerebra...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Nan Yan Zhengdong Wang Zhou Li Yang Zheng Nan Chang Kangjie Xu Qian Wang Xiaoxu Duan Source Type: research

Ecological and Health Risk Assessment of Heavy Metals Bioaccumulation in Ganges Fish Near Varanasi, India
Biol Trace Elem Res. 2023 Dec 26. doi: 10.1007/s12011-023-04020-4. Online ahead of print.ABSTRACTHeavy metal contamination in river Ganga is one of the factors for deterioration in its water quality and also adds to human health risks. We designed our study to achieve a holistic approach by not only estimating the concentration of heavy metals (lead, manganese, chromium, and cadmium) in the river water at different sites based on human anthropogenic activities but also in the fishes residing in the same sites that are collected for human consumption on daily basis. We found that Ganga River in Varanasi is highly loaded wit...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Bhargawi Mishra Geeta J Gautam Rajnish Kumar Chaturvedi Nasreen Ghazi Ansari Vijaya Nath Mishra Source Type: research

Selenium Nanoparticles Ameliorate Adverse Impacts of Aflatoxin in Nile Tilapia with Special Reference to Streptococcus agalactiae Infection
Biol Trace Elem Res. 2023 Dec 26. doi: 10.1007/s12011-023-04031-1. Online ahead of print.ABSTRACTAflatoxin B1 (AFB1) is a plant-origin toxin that could induce oxidative stress in fish. The micromineral selenium (Se) possesses well-documented antioxidant properties. To assess the ameliorative effects of SeNPs (1 mg/kg fish feed) on oxidative stress induced by AFB1 (500 μg/kg fish feed), Nile tilapia (32.2±1.7 g body weight) were distributed randomly and even in six groups for 8-week feeding trial. Live enzymes, AST, ALT, and ALP levels were increased in the serum of fish fed AFB1-contaminated diet, and the addition of SeN...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Ahmed H Sherif Mohsen A Zommara Source Type: research

The Association between Magnesium Depletion Score and Hypertension in US Adults: Evidence from the National Health and Nutrition Examination Survey (2007-2018)
This study aims to explore the link between MDS and hypertension (HTN) using the National Health and Nutrition Examination Survey (NHANES) data. A total of 9708 participants from NHANES (2007-2018) were enrolled to investigate MDS's connection with HTN. HTN was defined based on clinical guidelines. MDS classification (low, 0-1; middle, 2; high, 3-5) relied on alcohol consumption, diuretic use, proton-pump inhibitor (PPI) usage, and kidney disease. Multivariable logistic regression assessed MDS-HTN association. Subsequent analyses included interaction tests, subgroups, and sensitivity analysis. Each unit increase in MDS cor...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Mo-Yao Tan Chao-Yue Mo Qian Zhao Source Type: research

Antibiotic Residues and Zinc Concentrations in the Livers and Kidneys of Portuguese Piglets-Relationship to Antibiotic and Zinc Resistance in Intestinal Escherichia coli
This study aims to determine antibiotic residues and Zn concentration in piglets' livers (n = 56) and kidneys (n = 60); and to examine the correlation between the use of Zn and antibiotics, and resistance to Zn and antibiotics of Escherichia coli isolated from piglets' faeces (n = 60). Samples were collected from randomly selected healthy piglets (n = 60); antibiotic residues were quantified by ultra-high-performance-liquid-chromatography time-of-flight mass spectrometry (UHPLC-ToF-MS); Zn was quantified using flame atomic absorption spectrometry (FAAS); microbiological methods were used for E. coli isolation, antibiotic s...
Source: Biological Trace Element Research - December 26, 2023 Category: Biology Authors: Olga Cardoso Gabriela Assis Maria M Donato Sara Carolina Henriques Andreia Freitas Fernando Ramos Source Type: research

Evaluating the Protective Effects of Melatonin Against Chronic Iron Administration in Male Wistar Rats: a Comparative Analysis of Affective, Cognitive, and Oxidative Stress with EDTA Chelator
In this study, we performed a neurobehavioral assessment and biochemical determinations of oxidative stress levels in the hippocampus and prefrontal cortex of each animal. The results indicate that chronic exposure to iron sulfate induced anxiety-like depressive behavior, and cognitive impairment also increased the levels of lipid peroxidation and nitric oxide, and reduced the activity of catalase in the hippocampus and prefrontal cortex in male Wistar rats, suggesting the induction of oxidative stress. In contrast, these alterations were reversed by melatonin better than EDTA. The results of this study show that melatonin...
Source: Biological Trace Element Research - December 25, 2023 Category: Biology Authors: Ayoub Rezqaoui Soufiane Boumlah Aboubaker El Hessni Mohamed Yassine El Brouzi Abdelghafour El Hamzaoui Laila Ibouzine-Dine Samir Benkirane Manal Adnani Abdelhalem Mesfioui Source Type: research

Targeting Mitochondrial ATP-Synthase: Evolving Role of Chromium as a Regulator of Carbohydrate and Fat Metabolism
Biol Trace Elem Res. 2023 Dec 22. doi: 10.1007/s12011-023-04017-z. Online ahead of print.ABSTRACTThe micronutrient trivalent chromium, 3 + (Cr(III)), is postulated to play a role in carbohydrate, lipid, and protein metabolism. Although the mechanisms by which chromium mediates its actions are largely unknown, previous studies have suggested that pharmacological doses of chromium improve cardiometabolic symptoms by augmenting carbohydrate and lipid metabolism. Activation of AMP-activated protein kinase (AMPK) was among the many mechanisms proposed to explain the salutary actions of chromium on carbohydrate metabolism. Howev...
Source: Biological Trace Element Research - December 22, 2023 Category: Biology Authors: Vitoria Mattos Pereira Sreejayan Nair Source Type: research