Guide for Authors
Biological Psychiatry, founded in 1969, is an official journal of the Society of Biological Psychiatry and the first in the Biological Psychiatry family of journals. Companion titles include Biological Psychiatry: Cognitive Neuroscience and Neuroimaging and Biological Psychiatry: Global Open Science. The Society ’s purpose is to promote excellence in scientific research and education in fields that investigate the nature, causes, mechanisms, and treatments of disorders of thought, emotion, and behavior. (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 19, 2024 Category: Psychiatry Source Type: research
Society of Biological Psychiatry ’s 2024 Meeting
Welcome to Austin and this year ’s SOBP meeting! We are excited to gather with friends and colleagues to share the newest and most exciting findings while catching up on life in general. Now, nearly 25 years out from the “Decade of Brain” we chose this year’s theme “Is the Translational Medicine Approach Living Up to its Promise in Psychiatry?” to be self-reflective, evaluating the progress made in the field of Biological Psychiatry over this period. We hope to celebrate the areas of greatest success and consider ways of improving efforts in all areas to most effectively and efficiently make clinically meaningf...
Source: Biological Psychiatry - February 18, 2024 Category: Psychiatry Authors: Victoria Arrango, Gerard Sanacora Source Type: research
Erratum
to: “A Parabrachial-to-Amygdala Circuit That Determines Hemispheric Lateralization of Somatosensory Processing,” by Allen et al. (Biol Psychiatry 2023; 93:370–381); https://doi.org/10.1016/j.biopsych.2022.09.010. (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 14, 2024 Category: Psychiatry Tags: Erratum Source Type: research
The Perineuronal Net Protein Brevican Acts in Nucleus Accumbens Parvalbumin-expressing Interneurons of Adult Mice to Regulate Excitatory Synaptic Inputs and Motivated Behaviors
Experience-dependent functional adaptation of nucleus accumbens (NAc) circuitry underlies the development and expression of reward-motivated behaviors. Parvalbumin-expressing GABAergic interneurons (PVINs) within the NAc are required for this process. Perineuronal nets (PNNs) are extracellular matrix structures enriched around PVINs that arise during development and are proposed to mediate brain circuit stability. However, their function in adult NAc is largely unknown. Here we study the developmental emergence and adult regulation of PNNs in the NAc of male and female mice and test the cellular and behavioral consequences...
Source: Biological Psychiatry - February 10, 2024 Category: Psychiatry Authors: Mariah F. Hazlett, Victoria L. Hall, Esha Patel, Aaron Halvorsen, Nicole Calakos, Anne E. West Tags: Priority Communication Source Type: research
Specific patterns of endogenous functional connectivity are associated with harm avoidance in OCD
Individuals with OCD show persistent-avoidance behaviors, often in the absence of actual threat. Quality-of-life costs and heterogeneity support the need for novel brain-behavior intervention targets. Informed by mechanistic and anatomic studies of persistent-avoidance in rodents and non-human primates, our goal was to test whether connections within a hypothesized persistent-avoidance related network predicted OCD-related harm-avoidance (HA), a trait measure of persistent-avoidance. We hypothesized that 1)HA, not OCD diagnosis, would be associated with altered endogenous connectivity in at least one connection in the netw...
Source: Biological Psychiatry - February 7, 2024 Category: Psychiatry Authors: Merage Ghane, Lucas Trambaiolli, Michele A. Bertocci, Freddyson J. Martinez-Rivera, Henry W. Chase, Tyler Brady, Alex Skeba, Simona Graur, Lisa Bonar, Satish Iyengar, Gregory J. Quirk, Steven A. Rasmussen, Suzanne N. Haber, Mary L. Phillips Tags: Archival Report Source Type: research
Posterior Cerebellar Resting-State Functional Hypoconnectivity: A Neural Marker of Schizophrenia across Different Stages of Treatment Response
Identifying stable and consistent resting-state functional connectivity (rsFC) patterns across illness trajectories has the potential to be considered fundamental to the pathophysiology of schizophrenia. We aimed to identify consistent rsFC patterns across heterogeneous schizophrenia groups defined based on treatment response. (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 6, 2024 Category: Psychiatry Authors: Urvakhsh Meherwan Mehta, Dhruva Ithal, Neelabja Roy, Shreshth Shekhar, Ramajayam Govindaraj, Chaitra T. Ramachandraiah, Nicolas R. Bolo, Rose Dawn Bharath, Jagadisha Thirthalli, Ganesan Venkatasubramanian, Bangalore N. Gangadhar, Matcheri S. Keshavan Tags: Archival Report Source Type: research
Two Distinct Biotypes in Major Depression Unveiled
Major depressive disorder (MDD) is a globally prevalent mental health condition that exhibits diverse clinical features and a complex genetic makeup. Despite attempts to classify its heterogeneous presentation based on symptoms, these approaches, which are rooted in the diverse biological mechanisms of comparable symptoms, have not yielded treatment options grounded in empirical evidence (1). Addressing this challenge requires a direct stratification of biological heterogeneity by objectively identifying biotypes. (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Authors: Rammohan Shukla Tags: Commentary Source Type: research
A New Look at Gray Matter Decreases in Chronic Pain
Scientific views on chronic pain have evolved dramatically over the past decades. It has become increasingly clear that many types of chronic pain are promoted and maintained by changes in the brain that can occur after injury or insult to the body. These include remodeling of neural pathways, glial changes, and neuroinflammation (1). Central nervous system alterations can cause pain to spread beyond an initial site of injury, making it a systemic rather than a localized disorder. Co-occurring pain across body sites and etiologies is linked to shared genetic susceptibilities and common functional changes in the brain (2,3)...
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Authors: Tor D. Wager, Katerina Zorina-Lichtenwalter, Naomi P. Friedman Tags: Commentary Source Type: research
In This Issue
Volume 95, Number 5, March 1, 2024 (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Tags: In This Issue Source Type: research
Ultrahigh-Field Magnetic Resonance Spectroscopy Findings Do Not Support Previous Brain Metabolite Findings in Major Depressive Disorder
Major depressive disorder (MDD) constitutes a significant burden to individuals and society, with existing treatment approaches being ineffective for 30% of patients with MDD. Delineating the molecular pathogenesis of MDD is an essential area of research and may facilitate the identification of novel treatments corresponding with the disorder ’s molecular basis. (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Authors: Amanda J.F. Tamman, Chadi G. Abdallah Tags: Commentary Source Type: research
Editorial Board Page
(Source: Biological Psychiatry)
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Source Type: research
Subscribers Page
(Source: Biological Psychiatry)
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Source Type: research
Table of Contents
(Source: Biological Psychiatry)
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Source Type: research
Guide for Authors
Biological Psychiatry, founded in 1969, is an official journal of the Society of Biological Psychiatry and the first in the Biological Psychiatry family of journals. Companion titles include Biological Psychiatry: Cognitive Neuroscience and Neuroimaging and Biological Psychiatry: Global Open Science. The Society ’s purpose is to promote excellence in scientific research and education in fields that investigate the nature, causes, mechanisms, and treatments of disorders of thought, emotion, and behavior. (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 5, 2024 Category: Psychiatry Source Type: research
Long-term impact of early life stress on serotonin connectivity
Chronic childhood stress is a prominent risk factor for developing affective disorders, yet mechanisms underlying this association remain unclear. Maintenance of optimal serotonin (5-HT) levels during early postnatal development is critical for the maturation of brain circuits. Understanding the long-lasting effects of early life stress (ELS) on serotonin-modulated brain connectivity is crucial to develop treatments for affective disorders, arising from childhood stress. (Source: Biological Psychiatry)
Source: Biological Psychiatry - February 3, 2024 Category: Psychiatry Authors: Raksha Ramkumar, Moriah Edge-Partington, Dylan J. Terstege, Kabirat Adigun, Yi Ren, Nazmus S. Khan, Nahid Rouhi, Naila F. Jamani, Mio Tsutsui, Jonathan R. Epp, Derya Sargin Tags: Archival Report Source Type: research
