Issue Information
(Source: BioFactors)
Source: BioFactors - April 12, 2023 Category: Biochemistry Tags: ISSUE INFORMATION Source Type: research
Preface
(Source: BioFactors)
Source: BioFactors - April 11, 2023 Category: Biochemistry Authors: Aleksandra Mladenovic Tags: EDITORIAL Source Type: research
Curcumin ‐based nanoformulations alleviate wounds and related disorders: A comprehensive review
Most studies reported that the inflammatory cells are found in the wound area of the control as well as all various treatment groups, on day 3 posttreatment. But interestingly, unlike control groups, the curcumin (CUR)-involved systems showed the beginning of cell proliferation and migration, reepithelization, granulation generation, and collagen deposition from the first days of treatment. So, it is concluded that besides the inflammation phase, CUR plays a critical role also in other wound healing phases. AbstractDespite numerous advantages, curcumin's (CUR) low solubility and low bioavailability limit its employment as ...
Source: BioFactors - March 25, 2023 Category: Biochemistry Authors: Legha Ansari,
Habibeh Mashayekhi ‐Sardoo,
Vafa Baradaran Rahimi,
Roghayeh Yahyazadeh,
Majid Ghayour‐Mobarhan,
Vahid Reza Askari Tags: REVIEW ARTICLE Source Type: research
Sexually dimorphic metal alterations in childhood obesity are modulated by a complex interplay between inflammation, insulin, and sex hormones
In this study, we applied multi-elemental analysis to plasma and erythrocyte samples from an observational cohort comprising children with obesity, with and without insulin resistance, and healthy control children. Furthermore, a wide number of variables related to carbohydrate and lipid metabolism, inflammation, and sex hormones were also determined. Children with obesity, regardless of sex and insulin resistance status, showed increased plasma copper-to-zinc ratios. More interestingly, obesity-related erythroid alterations were found to be sex-dependent, with increased contents of iron, zinc, and copper being exclusively...
Source: BioFactors - March 25, 2023 Category: Biochemistry Authors: Álvaro González‐Domínguez,
Jesús Domínguez‐Riscart,
María Millán‐Martínez,
Alfonso María Lechuga‐Sancho,
Raúl González‐Domínguez Tags: RESEARCH ARTICLE Source Type: research
Curcumin ‐based nanoformulations alleviate wounds and related disorders: A comprehensive review
Most studies reported that the inflammatory cells are found in the wound area of the control as well as all various treatment groups, on day 3 posttreatment. But interestingly, unlike control groups, the curcumin (CUR)-involved systems showed the beginning of cell proliferation and migration, reepithelization, granulation generation, and collagen deposition from the first days of treatment. So, it is concluded that besides the inflammation phase, CUR plays a critical role also in other wound healing phases. AbstractDespite numerous advantages, curcumin's (CUR) low solubility and low bioavailability limit its employment as ...
Source: BioFactors - March 24, 2023 Category: Biochemistry Authors: Legha Ansari,
Habibeh Mashayekhi ‐Sardoo,
Vafa Baradaran Rahimi,
Roghayeh Yahyazadeh,
Majid Ghayour‐Mobarhan,
Vahid Reza Askari Tags: REVIEW ARTICLE Source Type: research
Sexually dimorphic metal alterations in childhood obesity are modulated by a complex interplay between inflammation, insulin, and sex hormones
In this study, we applied multi-elemental analysis to plasma and erythrocyte samples from an observational cohort comprising children with obesity, with and without insulin resistance, and healthy control children. Furthermore, a wide number of variables related to carbohydrate and lipid metabolism, inflammation, and sex hormones were also determined. Children with obesity, regardless of sex and insulin resistance status, showed increased plasma copper-to-zinc ratios. More interestingly, obesity-related erythroid alterations were found to be sex-dependent, with increased contents of iron, zinc, and copper being exclusively...
Source: BioFactors - March 22, 2023 Category: Biochemistry Authors: Álvaro González‐Domínguez,
Jesús Domínguez‐Riscart,
María Millán‐Martínez,
Alfonso María Lechuga‐Sancho,
Raúl González‐Domínguez Tags: RESEARCH ARTICLE Source Type: research
Metformin and thymoquinone co ‐treatment enhance 5‐fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells
In conclusion, this is the first study to reveal enhanced anti-cancer effects for metformin/thymoquinone in CRC that were superior to all monotherapies and the other dual therapies. However, the triple therapy approach showed the best tumoricidal actions related to cell cycle arrest and apoptosis in all cell lines, possibly by enhancing oxidative glycolysis and augmenting oxidative stress through stronger modulation of the PI3K/mTOR/HIF1α oncogenic network. (Source: BioFactors)
Source: BioFactors - March 17, 2023 Category: Biochemistry Authors: Wesam F. Farrash,
Akhmed Aslam,
Riyad Almaimani,
Faisal Minshawi,
Hussain Almasmoum,
Aiman Alsaegh,
Mohammad S. Iqbal,
Aisha Tabassum,
Mohamed E. Elzubier,
Mahmoud Z. El ‐Readi,
Amani A. Mahbub,
Shakir Idris,
Bassem Refaat Tags: RESEARCH ARTICLE Source Type: research
Trace elements as potential modulators of puberty ‐induced amelioration of oxidative stress and inflammation in childhood obesity
We found puberty to be characterized by better inflammatory and oxidative control, as reflected by lower levels of C-reactive protein and oxidative damage markers, as well as improved antioxidant defense. This was in turn accompanied by a healthier multielemental profile, with increased levels of essential elements involved in the antioxidant system and metabolic control (metalloproteins containing zinc, molybdenum, selenium, and manganese) and decreased content of potentially deleterious species (total copper, labile free iron). Therefore, our findings suggest that children with obesity have an exacerbated inflammatory an...
Source: BioFactors - March 17, 2023 Category: Biochemistry Authors: Álvaro González‐Domínguez,
Jesús Domínguez‐Riscart,
María Millán‐Martínez,
Rosa María Mateos‐Bernal,
Alfonso María Lechuga‐Sancho,
Raúl González‐Domínguez Tags: RESEARCH ARTICLE Source Type: research
Mechanisms of cancer cell death induction by triptolide
This paper reviewed the induction or resistance to different cell death mechanisms such as apoptosis, autophagic cell death, senescence, pyroptosis, ferroptosis, and necrosis following the administration of triptolide. The potential of triptolide may make it an effective adjuvant to enhance cancer cell death in combination with anticancer drugs. AbstractDrug resistance is a hot topic issue in cancer research and therapy. Although cancer therapy including radiotherapy and anti-cancer drugs can kill malignant cells within the tumor, cancer cells can develop a wide range of mechanisms to resist the toxic effects of anti-cance...
Source: BioFactors - March 7, 2023 Category: Biochemistry Authors: Ali Hamid AbdulHussein,
Muataz Mohammed Al ‐Taee,
Zahra Abdul Radih,
Dhuha Salman Aljuboory,
Zainab Qasim Mohammed,
Tabarak Sami Hashesh,
Yassine Riadi,
Salema K. Hadrawi,
Masoud Najafi Tags: REVIEW ARTICLE Source Type: research
Retraction
This article, published online on 29 November 2019 in Wiley Online Library, has been retracted by agreement between the International Union of Biochemistry and Molecular Biology, the Editor in Chief (Dr. Angelo Azzi), and Wiley Periodicals LLC. The retraction has been agreed following an investigation based on allegations raised by a third party. Evidence for image manipulation was found in figures 1, 3, 4, 5, 6, and 7. As a result, the conclusions of this article are considered to be invalid. (Source: BioFactors)
Source: BioFactors - February 26, 2023 Category: Biochemistry Tags: RETRACTION Source Type: research
Issue Information
(Source: BioFactors)
Source: BioFactors - February 25, 2023 Category: Biochemistry Tags: ISSUE INFORMATION Source Type: research
