Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Nuclear accumulation of MKL1 in luminal breast cancer cells impairs genomic activity of ERα and is associated with endocrine resistance
Publication date: Available online 27 February 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsAuthor(s): Charly Jehanno, Tamara Fernandez-Calero, Denis Habauzit, Stephane Avner, Frederic Percevault, Emmanuelle Jullion, Pascale Le Goff, Marie May Coissieux, Simone Muenst, Monica Marin, Denis Michel, Raphaël Métivier, Gilles Flouriot (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 28, 2020 Category: Genetics & Stem Cells Source Type: research

TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture
Publication date: Available online 27 February 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsAuthor(s): Luzhang Ji, Xiangru Huo, Yuwen Zhang, Zixiang Yan, Qianfeng Wang, Bo Wen (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 28, 2020 Category: Genetics & Stem Cells Source Type: research

Noncoding RNAs in control of gene expression
Publication date: Available online 27 February 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsAuthor(s): Kotb Abdelmohsen (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 28, 2020 Category: Genetics & Stem Cells Source Type: research

Dissecting the in vivo dynamics of transcription locking due to positive supercoiling buildup
Publication date: Available online 27 February 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsAuthor(s): Cristina S.D. Palma, Vinodh Kandavalli, Mohamed N.M. Bahrudeen, Marco Minoia, Vatsala Chauhan, Suchintak Dash, Andre S. Ribeiro (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 28, 2020 Category: Genetics & Stem Cells Source Type: research

Editorial Board
Publication date: March 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Volume 1863, Issue 3Author(s): (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 26, 2020 Category: Genetics & Stem Cells Source Type: research

ELL-associated factors EAF1/2 negatively regulate HIV-1 transcription through inhibition of Super Elongation Complex formation
In this study, we show that EAF1/2 inhibit the SEC-dependent and Tat-activated HIV-1 transcription. EAF1/2 are found to interact with the SEC components in an ELL1/2-dependent manner. Surprisingly, the depletion of EAF1/2 increases the SEC formation and occupancy on the HIV-1 proviral DNA, thereby stimulating Tat transactivation of HIV-1. Although EAF1/2 interact with members of the SEC in a ELL-dependent manner, this interaction competes with the binding of the scaffolding subunit AFF1 with ELL, thus reducing the SEC formation. Together, these data reveal how EAF1/2 regulate the SEC formation to control HIV-1 transcriptio...
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 20, 2020 Category: Genetics & Stem Cells Source Type: research

Navigation through the twists and turns of RNA sequencing technologies: Application to bacterial regulatory RNAs
This article is part of a Special Issue entitled: RNA and gene control in bacteria edited by Dr. M. Guillier and F. Repoila. (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 15, 2020 Category: Genetics & Stem Cells Source Type: research

MLL fusion proteins and transcriptional control
Publication date: Available online 12 February 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsAuthor(s): Robert K. SlanyAbstractThe highly leukemogenic MLL fusion proteins have a unique mechanism of action. This review summarizes the current knowledge of how MLL fusions interact with the transcriptional machinery and it proposes a hypothesis how these proteins modify transcriptional control to act as transcriptional amplifiers causing runaway production of certain RNAs that transform hematopoietic cells. (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 14, 2020 Category: Genetics & Stem Cells Source Type: research

sRNA-mediated control in bacteria: An increasing diversity of regulatory mechanisms
This article is part of a Special Issue entitled: RNA and gene control in bacteria edited by Dr. M. Guillier and F. Repoila. (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 14, 2020 Category: Genetics & Stem Cells Source Type: research

Regulation of RNA processing and degradation in bacteria
This article is part of a Special Issue entitled: RNA and gene control in bacteria edited by Dr. M. Guillier and F. Repoila. (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 14, 2020 Category: Genetics & Stem Cells Source Type: research

Transcriptomic landscape, gene signatures and regulatory profile of aging in the human brain
This article is part of a Special Issue entitled: Transcriptional Profiles and Regulatory Gene Networks edited by Dr. Federico Manuel Giorgi and Dr. Shaun Mahony. (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 9, 2020 Category: Genetics & Stem Cells Source Type: research

Bacterial growth physiology and RNA metabolism
This article is part of a Special Issue entitled: RNA and gene control in bacteria edited by Dr. M. Guillier and F. Repoila. (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 8, 2020 Category: Genetics & Stem Cells Source Type: research

Riboswitch regulation mechanisms: RNA, metabolites and regulatory proteins
Publication date: Available online 7 February 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsAuthor(s): Anne-Sophie Vézina Bédard, Elsa D.M. Hien, Daniel A. LafontaineAbstractRiboswitches are RNA sensors that have been shown to modulate the expression of downstream genes by altering their structure upon metabolite binding. Riboswitches are unique among cellular regulators in that metabolite detection is strictly performed using RNA interactions with the sensed metabolite and in which no regulatory protein is needed to mediate the interaction. However, recent studies have shed light on riboswi...
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 8, 2020 Category: Genetics & Stem Cells Source Type: research

Editorial Board
Publication date: February 2020Source: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Volume 1863, Issue 2Author(s): (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 4, 2020 Category: Genetics & Stem Cells Source Type: research

The interaction between the F55 virus-encoded transcription regulator and the RadA host recombinase reveals a common strategy in Archaea and Bacteria to sense the UV-induced damage to the host DNA
In this study we have applied an integrated biochemical approach based on a variant of the EMSA assay coupled to mass spectrometry analyses to identify the proteins associated with F55 when bound to its specific DNA promoter sequences. Among the putative F55 interactors, we identified RadA and showed that the archaeal molecular components F55 and RadA are functional homologs of bacteriophage λ (factor CI) and Escherichia coli (RecA) system.Graphical abstract (Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms)
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - February 1, 2020 Category: Genetics & Stem Cells Source Type: research