Time to treat the climate and nature crisis as one indivisible global health emergency
Biochem Cell Biol. 2023 Dec 1;101(6):i-iii. doi: 10.1139/bcb-2023-0329.NO ABSTRACTPMID:38055655 | DOI:10.1139/bcb-2023-0329 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - December 6, 2023 Category: Biochemistry Source Type: research
Time to treat the climate and nature crisis as one indivisible global health emergency
Biochem Cell Biol. 2023 Dec 1;101(6):i-iii. doi: 10.1139/bcb-2023-0329.NO ABSTRACTPMID:38055655 | DOI:10.1139/bcb-2023-0329 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - December 6, 2023 Category: Biochemistry Source Type: research
Time to treat the climate and nature crisis as one indivisible global health emergency
Biochem Cell Biol. 2023 Dec 1;101(6):i-iii. doi: 10.1139/bcb-2023-0329.NO ABSTRACTPMID:38055655 | DOI:10.1139/bcb-2023-0329 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - December 6, 2023 Category: Biochemistry Source Type: research
Time to treat the climate and nature crisis as one indivisible global health emergency
Biochem Cell Biol. 2023 Dec 1;101(6):i-iii. doi: 10.1139/bcb-2023-0329.NO ABSTRACTPMID:38055655 | DOI:10.1139/bcb-2023-0329 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - December 6, 2023 Category: Biochemistry Source Type: research
Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels
This study focuses on profilin (Pfy1) in the budding yeast Saccharomyces cerevisiae. The primary sequence of yeast Pfy1 and its metazoan orthologs diverge vastly. However, structural elements of profilin are conserved among different species. To date, the full spectrum of Pfy1 functions has yet to be defined. The current work explores the possible involvement of yeast profilin in nuclear protein import. To this end, a panel of well characterized yeast profilin mutants was evaluated. The experiments demonstrate that (i) yeast profilin regulates nuclear protein import, (ii) determines the subcellular localization of essentia...
Source: Biochemistry and Cell Biology - December 4, 2023 Category: Biochemistry Authors: Ursula Stochaj Source Type: research
Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels
This study focuses on profilin (Pfy1) in the budding yeast Saccharomyces cerevisiae. The primary sequence of yeast Pfy1 and its metazoan orthologs diverge vastly. However, structural elements of profilin are conserved among different species. To date, the full spectrum of Pfy1 functions has yet to be defined. The current work explores the possible involvement of yeast profilin in nuclear protein import. To this end, a panel of well characterized yeast profilin mutants was evaluated. The experiments demonstrate that (i) yeast profilin regulates nuclear protein import, (ii) determines the subcellular localization of essentia...
Source: Biochemistry and Cell Biology - December 4, 2023 Category: Biochemistry Authors: Ursula Stochaj Source Type: research
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers
In this report, we analyzed chromatin immunoprecipitation sequencing data for the genomic location of H4R3me2a in the breast cancer cell line MCF7. As in avian cells, MCF7 H4R3me2a is present in intronic and intergenic regions. Nucleosomes with H4R3me2a and H3K27ac next to nucleosome-free regions are found at super-enhancers, enhancers, and promoter regions of expressed genes. Genes with critical roles in breast cancer cells have broad domains of nucleosomes with H4R3me2a, H3K27ac, and H3K4me3. Our results are consistent with PRMT1-mediated H4R3me2a playing a key role in the chromatin organization of regulatory regions of ...
Source: Biochemistry and Cell Biology - November 27, 2023 Category: Biochemistry Authors: Sadhana R N Sudhakar Li Wu Shrinal Patel Athanasios Zovoilis James R Davie Source Type: research
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers
In this report, we analyzed chromatin immunoprecipitation sequencing data for the genomic location of H4R3me2a in the breast cancer cell line MCF7. As in avian cells, MCF7 H4R3me2a is present in intronic and intergenic regions. Nucleosomes with H4R3me2a and H3K27ac next to nucleosome-free regions are found at super-enhancers, enhancers, and promoter regions of expressed genes. Genes with critical roles in breast cancer cells have broad domains of nucleosomes with H4R3me2a, H3K27ac, and H3K4me3. Our results are consistent with PRMT1-mediated H4R3me2a playing a key role in the chromatin organization of regulatory regions of ...
Source: Biochemistry and Cell Biology - November 27, 2023 Category: Biochemistry Authors: Sadhana R N Sudhakar Li Wu Shrinal Patel Athanasios Zovoilis James R Davie Source Type: research
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers
In this report, we analyzed chromatin immunoprecipitation sequencing data for the genomic location of H4R3me2a in the breast cancer cell line MCF7. As in avian cells, MCF7 H4R3me2a is present in intronic and intergenic regions. Nucleosomes with H4R3me2a and H3K27ac next to nucleosome-free regions are found at super-enhancers, enhancers, and promoter regions of expressed genes. Genes with critical roles in breast cancer cells have broad domains of nucleosomes with H4R3me2a, H3K27ac, and H3K4me3. Our results are consistent with PRMT1-mediated H4R3me2a playing a key role in the chromatin organization of regulatory regions of ...
Source: Biochemistry and Cell Biology - November 27, 2023 Category: Biochemistry Authors: Sadhana R N Sudhakar Li Wu Shrinal Patel Athanasios Zovoilis James R Davie Source Type: research
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers
In this report, we analyzed chromatin immunoprecipitation sequencing data for the genomic location of H4R3me2a in the breast cancer cell line MCF7. As in avian cells, MCF7 H4R3me2a is present in intronic and intergenic regions. Nucleosomes with H4R3me2a and H3K27ac next to nucleosome-free regions are found at super-enhancers, enhancers, and promoter regions of expressed genes. Genes with critical roles in breast cancer cells have broad domains of nucleosomes with H4R3me2a, H3K27ac, and H3K4me3. Our results are consistent with PRMT1-mediated H4R3me2a playing a key role in the chromatin organization of regulatory regions of ...
Source: Biochemistry and Cell Biology - November 27, 2023 Category: Biochemistry Authors: Sadhana R N Sudhakar Li Wu Shrinal Patel Athanasios Zovoilis James R Davie Source Type: research
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers
In this report, we analyzed chromatin immunoprecipitation sequencing data for the genomic location of H4R3me2a in the breast cancer cell line MCF7. As in avian cells, MCF7 H4R3me2a is present in intronic and intergenic regions. Nucleosomes with H4R3me2a and H3K27ac next to nucleosome-free regions are found at super-enhancers, enhancers, and promoter regions of expressed genes. Genes with critical roles in breast cancer cells have broad domains of nucleosomes with H4R3me2a, H3K27ac, and H3K4me3. Our results are consistent with PRMT1-mediated H4R3me2a playing a key role in the chromatin organization of regulatory regions of ...
Source: Biochemistry and Cell Biology - November 27, 2023 Category: Biochemistry Authors: Sadhana R N Sudhakar Li Wu Shrinal Patel Athanasios Zovoilis James R Davie Source Type: research
Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers
In this report, we analyzed chromatin immunoprecipitation sequencing data for the genomic location of H4R3me2a in the breast cancer cell line MCF7. As in avian cells, MCF7 H4R3me2a is present in intronic and intergenic regions. Nucleosomes with H4R3me2a and H3K27ac next to nucleosome-free regions are found at super-enhancers, enhancers, and promoter regions of expressed genes. Genes with critical roles in breast cancer cells have broad domains of nucleosomes with H4R3me2a, H3K27ac, and H3K4me3. Our results are consistent with PRMT1-mediated H4R3me2a playing a key role in the chromatin organization of regulatory regions of ...
Source: Biochemistry and Cell Biology - November 27, 2023 Category: Biochemistry Authors: Sadhana R N Sudhakar Li Wu Shrinal Patel Athanasios Zovoilis James R Davie Source Type: research
Correction: Protective effect of nitronyl nitroxide against hypoxia-induced damage in PC12 cells
Biochem Cell Biol. 2023 Nov 24. doi: 10.1139/bcb-2023-0321. Online ahead of print.NO ABSTRACTPMID:37997895 | DOI:10.1139/bcb-2023-0321 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - November 24, 2023 Category: Biochemistry Authors: Hongbo Luo Wei Sun Jin Shao Huiping Ma Zhengping Jia Linlin Jing Source Type: research
Correction: Protective effect of nitronyl nitroxide against hypoxia-induced damage in PC12 cells
Biochem Cell Biol. 2023 Nov 24. doi: 10.1139/bcb-2023-0321. Online ahead of print.NO ABSTRACTPMID:37997895 | DOI:10.1139/bcb-2023-0321 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - November 24, 2023 Category: Biochemistry Authors: Hongbo Luo Wei Sun Jin Shao Huiping Ma Zhengping Jia Linlin Jing Source Type: research
Correction: Protective effect of nitronyl nitroxide against hypoxia-induced damage in PC12 cells
Biochem Cell Biol. 2023 Nov 24. doi: 10.1139/bcb-2023-0321. Online ahead of print.NO ABSTRACTPMID:37997895 | DOI:10.1139/bcb-2023-0321 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - November 24, 2023 Category: Biochemistry Authors: Hongbo Luo Wei Sun Jin Shao Huiping Ma Zhengping Jia Linlin Jing Source Type: research
