SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55
In conclusion, our results suggest that SUMO-3 or SUMO-3-modified proteins modulate the localization, stability, and RING ubiquitin ligase activity of TRIM55.PMID:37703582 | DOI:10.1139/bcb-2023-0153 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - September 13, 2023 Category: Biochemistry Authors: Nour El Houda Hammami Natacha M érindol M élodie B Plourde Tara Maisonnet Sophie Lebel Lionel Berthoux Source Type: research
SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55
In conclusion, our results suggest that SUMO-3 or SUMO-3-modified proteins modulate the localization, stability, and RING ubiquitin ligase activity of TRIM55.PMID:37703582 | DOI:10.1139/bcb-2023-0153 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - September 13, 2023 Category: Biochemistry Authors: Nour El Houda Hammami Natacha M érindol M élodie B Plourde Tara Maisonnet Sophie Lebel Lionel Berthoux Source Type: research
SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55
In conclusion, our results suggest that SUMO-3 or SUMO-3-modified proteins modulate the localization, stability, and RING ubiquitin ligase activity of TRIM55.PMID:37703582 | DOI:10.1139/bcb-2023-0153 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - September 13, 2023 Category: Biochemistry Authors: Nour El Houda Hammami Natacha M érindol M élodie B Plourde Tara Maisonnet Sophie Lebel Lionel Berthoux Source Type: research
SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55
In conclusion, our results suggest that SUMO-3 or SUMO-3-modified proteins modulate the localization, stability, and RING ubiquitin ligase activity of TRIM55.PMID:37703582 | DOI:10.1139/bcb-2023-0153 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - September 13, 2023 Category: Biochemistry Authors: Nour El Houda Hammami Natacha M érindol M élodie B Plourde Tara Maisonnet Sophie Lebel Lionel Berthoux Source Type: research
SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55
In conclusion, our results suggest that SUMO-3 or SUMO-3-modified proteins modulate the localization, stability, and RING ubiquitin ligase activity of TRIM55.PMID:37703582 | DOI:10.1139/bcb-2023-0153 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - September 13, 2023 Category: Biochemistry Authors: Nour El Houda Hammami Natacha M érindol M élodie B Plourde Tara Maisonnet Sophie Lebel Lionel Berthoux Source Type: research
SUMO-3 promotes the ubiquitin-dependent turnover of TRIM55
In conclusion, our results suggest that SUMO-3 or SUMO-3-modified proteins modulate the localization, stability, and RING ubiquitin ligase activity of TRIM55.PMID:37703582 | DOI:10.1139/bcb-2023-0153 (Source: Biochemistry and Cell Biology)
Source: Biochemistry and Cell Biology - September 13, 2023 Category: Biochemistry Authors: Nour El Houda Hammami Natacha M érindol M élodie B Plourde Tara Maisonnet Sophie Lebel Lionel Berthoux Source Type: research
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0134. Online ahead of print.ABSTRACTThe cGAS-STING axis integrates DNA damage and cellular stress with type I interferon (IFN) signalling to facilitate transcriptional changes underlying inflammatory stress responses. The cGAS-STING pathway responds to cytosolic DNA in the form of dsDNA, micronuclei, and LINE-1 (L1) retroelements. L1 retroelements are a class of self-propagating non-LTR transposons that have remained highly active in our genomes. L1 retroelements are emerging as important inducers of cGAS-STING and interferon signalling, which are often dysregulated in ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Sabateeshan Mathavarajah Graham Dellaire Source Type: research
Crosstalk between Chromatin, Chromosomes, and Epigenetics
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0165. Online ahead of print.ABSTRACTThe International Asilomar Chromatin, Chromosomes, and Epigenetics Conference was held online from December 8 - 10, 2022. Topics of this year's conference included chromosome dysregulation, genome integrity, nuclear organization, regulation of chromatin, epigenetics, transcription, and gene regulation in cell differentiation and disease. The meeting featured four keynote speakers including Yamini Dalal (National Cancer Institute, USA), Meaghan Jones (University of Manitoba, Canada), Pedro Rocha (National Institute of Child Health and ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Alyssa Ialongo Ssu-Yu Yeh Ho Sung Rhee Source Type: research
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0134. Online ahead of print.ABSTRACTThe cGAS-STING axis integrates DNA damage and cellular stress with type I interferon (IFN) signalling to facilitate transcriptional changes underlying inflammatory stress responses. The cGAS-STING pathway responds to cytosolic DNA in the form of dsDNA, micronuclei, and LINE-1 (L1) retroelements. L1 retroelements are a class of self-propagating non-LTR transposons that have remained highly active in our genomes. L1 retroelements are emerging as important inducers of cGAS-STING and interferon signalling, which are often dysregulated in ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Sabateeshan Mathavarajah Graham Dellaire Source Type: research
Crosstalk between Chromatin, Chromosomes, and Epigenetics
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0165. Online ahead of print.ABSTRACTThe International Asilomar Chromatin, Chromosomes, and Epigenetics Conference was held online from December 8 - 10, 2022. Topics of this year's conference included chromosome dysregulation, genome integrity, nuclear organization, regulation of chromatin, epigenetics, transcription, and gene regulation in cell differentiation and disease. The meeting featured four keynote speakers including Yamini Dalal (National Cancer Institute, USA), Meaghan Jones (University of Manitoba, Canada), Pedro Rocha (National Institute of Child Health and ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Alyssa Ialongo Ssu-Yu Yeh Ho Sung Rhee Source Type: research
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0134. Online ahead of print.ABSTRACTThe cGAS-STING axis integrates DNA damage and cellular stress with type I interferon (IFN) signalling to facilitate transcriptional changes underlying inflammatory stress responses. The cGAS-STING pathway responds to cytosolic DNA in the form of dsDNA, micronuclei, and LINE-1 (L1) retroelements. L1 retroelements are a class of self-propagating non-LTR transposons that have remained highly active in our genomes. L1 retroelements are emerging as important inducers of cGAS-STING and interferon signalling, which are often dysregulated in ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Sabateeshan Mathavarajah Graham Dellaire Source Type: research
Crosstalk between Chromatin, Chromosomes, and Epigenetics
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0165. Online ahead of print.ABSTRACTThe International Asilomar Chromatin, Chromosomes, and Epigenetics Conference was held online from December 8 - 10, 2022. Topics of this year's conference included chromosome dysregulation, genome integrity, nuclear organization, regulation of chromatin, epigenetics, transcription, and gene regulation in cell differentiation and disease. The meeting featured four keynote speakers including Yamini Dalal (National Cancer Institute, USA), Meaghan Jones (University of Manitoba, Canada), Pedro Rocha (National Institute of Child Health and ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Alyssa Ialongo Ssu-Yu Yeh Ho Sung Rhee Source Type: research
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0134. Online ahead of print.ABSTRACTThe cGAS-STING axis integrates DNA damage and cellular stress with type I interferon (IFN) signalling to facilitate transcriptional changes underlying inflammatory stress responses. The cGAS-STING pathway responds to cytosolic DNA in the form of dsDNA, micronuclei, and LINE-1 (L1) retroelements. L1 retroelements are a class of self-propagating non-LTR transposons that have remained highly active in our genomes. L1 retroelements are emerging as important inducers of cGAS-STING and interferon signalling, which are often dysregulated in ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Sabateeshan Mathavarajah Graham Dellaire Source Type: research
Crosstalk between Chromatin, Chromosomes, and Epigenetics
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0165. Online ahead of print.ABSTRACTThe International Asilomar Chromatin, Chromosomes, and Epigenetics Conference was held online from December 8 - 10, 2022. Topics of this year's conference included chromosome dysregulation, genome integrity, nuclear organization, regulation of chromatin, epigenetics, transcription, and gene regulation in cell differentiation and disease. The meeting featured four keynote speakers including Yamini Dalal (National Cancer Institute, USA), Meaghan Jones (University of Manitoba, Canada), Pedro Rocha (National Institute of Child Health and ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Alyssa Ialongo Ssu-Yu Yeh Ho Sung Rhee Source Type: research
LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease
Biochem Cell Biol. 2023 Aug 29. doi: 10.1139/bcb-2023-0134. Online ahead of print.ABSTRACTThe cGAS-STING axis integrates DNA damage and cellular stress with type I interferon (IFN) signalling to facilitate transcriptional changes underlying inflammatory stress responses. The cGAS-STING pathway responds to cytosolic DNA in the form of dsDNA, micronuclei, and LINE-1 (L1) retroelements. L1 retroelements are a class of self-propagating non-LTR transposons that have remained highly active in our genomes. L1 retroelements are emerging as important inducers of cGAS-STING and interferon signalling, which are often dysregulated in ...
Source: Biochemistry and Cell Biology - August 29, 2023 Category: Biochemistry Authors: Sabateeshan Mathavarajah Graham Dellaire Source Type: research
