Best Practice and Research. Clinical Endocrinology and Metabolism 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Prevalence, Diagnosis and Outcomes of Treatment for Primary Aldosteronism
Publication date: Available online 5 December 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Yuhong Yang, Martin Reincke, Tracy Ann WilliamsAbstractPrimary aldosteronism (PA) is the most common potentially curable form of hypertension. The overproduction of aldosterone leads to an increased risk of cardiovascular and cerebrovascular events as well as adverse effects to the heart and kidney and psychological disorders. PA is mainly caused by unilateral aldosterone excess due to an aldosterone-producing adenoma or bilateral excess due to bilateral adrenocortical hyperplasia. The diagnostic...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - December 6, 2019 Category: Endocrinology Source Type: research
Thyroid gland and brain: Enigma of Hashimoto's encephalopathy
Publication date: Available online 23 November 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Leonid P. Churilov, Polina A. Sobolevskaia, Yuri I. StroevThe versatile clinical manifestations of the Hashimoto's chronic autoimmune thyroiditis often include psycho-neurological disorders. Although hypothyroidism disturbs significantly the ontogenesis and functions of central nervous system, causing in severe cases of myxedema profound impairment of cognitive abilities and even psychosis, the behavioral, motor and other psychoneurological disorders accompany euthyroid and slightly hypothyroid ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - December 2, 2019 Category: Endocrinology Source Type: research
Infertility in women with systemic autoimmune diseases
Publication date: Available online 2 December 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Jamilya Khizroeva, Cecilia Nalli, Victoria Bitsadze, Andrea Lojacono, Sonia Zatti, Laura Andreoli, Angela Tincani, Yehuda Shoenfeld, Alexander MakatsariyaAbstractInfertility consists by definition in ” failure to achieve a clinical pregnancy after 12 months or more of regular unprotected intercourse” while the term subfertility means a delay to achieve pregnancy. Several factors can contribute to infertility or subfertility in patients with systemic autoimmune diseases. The association of sys...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - December 2, 2019 Category: Endocrinology Source Type: research
Novel Therapies for Thyroid Autoimmune Diseases: an update
Publication date: Available online 28 November 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Silvia Martina Ferrari, Poupak Fallahi, Giusy Elia, Francesca Ragusa, Stefania Camastra, Sabrina Rosaria Paparo, Claudia Giusti, Debora Gonnella, Ilaria Ruffilli, Yehuda Shoenfeld, Alessandro AntonelliAbstractA Th1 immune-preponderance has been shown in the immunopathogenesis of autoimmune thyroiditis (AT), Graves’ disease (GD) and Graves’ Ophthalmopathy (GO), in which the Th1-chemokines (CXCL9, CXCL10, CXCL11), and their (C-X-C)R3 receptor, have a crucial role. Methimazole, and corticostero...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - November 29, 2019 Category: Endocrinology Source Type: research
Hashimotos’ Thyroiditis: epidemiology, pathogenesis, clinic and therapy
Publication date: Available online 26 November 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Francesca Ragusa, Poupak Fallahi, Giusy Elia, Debora Gonnella, Sabrina Rosaria Paparo, Claudia Giusti, Leonid.P. Churilov, Silvia Martina Ferrari, Alessandro AntonelliAbstractHashimoto’s thyroiditis (HT), the most frequent autoimmune thyroid disorders (AITDs), is the leading cause of hypothyroidism in the iodine-sufficient areas of the world. About 20-30% of patients suffers from HT, whose cause is thought to be a combination of genetic susceptibility and environmental factors that causes the ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - November 27, 2019 Category: Endocrinology Source Type: research
Primary Aldosteronism: treatment of the disease, and new therapeutic approaches
Publication date: Available online 26 November 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): John FunderAbstractPrimary aldosteronism is currently considered to represent 5-13% of hypertension, yet fewer than 1% of patients with the disorder are ever diagnosed and treated. Current management of patients screened and confirmed positive for primary aldosteronism involves imaging, and with very few exceptions adrenal venous sampling to lateralize (or not) hyperaldosteronism. Unilateral disease is treated by adrenalectomy: bilateral disease by mineralocorticoid receptor antagonists and conv...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - November 27, 2019 Category: Endocrinology Source Type: research
Thyroid Nodules and Cancer during Pregnancy, Post-partum and Preconception Planning: Addressing the Uncertainties and Challenges
Publication date: Available online 22 November 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Maria Papaleontiou, Megan R. HaymartAbstractThyroid nodules and thyroid cancer have become increasingly common worldwide. When discovered during pregnancy, they pose unique diagnostic and therapeutic challenges for both the treating physician and the patient. The benefits of treatment should be carefully weighed against risks that may adversely impact maternal and fetal health. In this review, we present current knowledge and controversies surrounding the management of thyroid nodules and thyroi...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - November 23, 2019 Category: Endocrinology Source Type: research
Thyroid Gland And Brain: Enigma Of Hashimoto’s Encephalopathy
Publication date: Available online 23 November 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Leonid P. Churilov, Polina A. Sobolevskaia, Yuri I. StroevAbstractThe versatile clinical manifestations of the Hashimoto’s chronic autoimmune thyroiditis often include psycho-neurological disorders. Although hypothyroidism disturbs significantly the ontogenesis and functions of central nervous system, causing in severe cases of myxoedema profound impairment of cognitive abilities and even psychosis, the behavioural, motor and other psychoneurological disorders accompany euthyroid and slightly ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - November 23, 2019 Category: Endocrinology Source Type: research
Editorial Board
Publication date: October 2019Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 33, Issue 5Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - November 20, 2019 Category: Endocrinology Source Type: research
Metastatic Pheochromocytoma and Paraganglioma: Management of Endocrine Manifestations, Surgery and Ablative Procedures, and Systemic Therapies
Publication date: Available online 24 October 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Sina Jasim, Camilo JimenezAbstractMetastatic pheochromocytomas and paragangliomas (MPPGs) are rare neuroendocrine tumors. Most patients present with advanced disease that is associated with manifestations of catecholamine release. Surgical resection of the primary tumor and ablative therapies of metastases—whenever possible—may improve clinical outcomes and, perhaps, lengthen the patient’s overall survival. Significant steps in understanding the genetic alterations linked to MPPGs and scien...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - October 25, 2019 Category: Endocrinology Source Type: research
Modern endocrine surgery – Striving for a better quality of life
Publication date: August 2019Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 33, Issue 4Author(s): Henning Dralle, Frank Weber (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - October 24, 2019 Category: Endocrinology Source Type: research
Editorial Board
Publication date: August 2019Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 33, Issue 4Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - October 24, 2019 Category: Endocrinology Source Type: research
Disease monitoring of patients with pheochromocytoma or paraganglioma by biomarkers and imaging studies
Publication date: Available online 21 October 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Florentine Schreiner, Felix BeuschleinAbstractPheochromocytoma and paraganglioma (PPGL) are rare neuroendocrine tumors, a large proportion of which secrete catecholamines. PPGL are associated with a high cardiovascular morbidity and come with a risk of malignancy. The therapy of choice is surgical resection. Nevertheless, PPGL are associated with a lifelong risk of tumor persistence or recurrence. Currently, there are no clinical, biochemical, histopathological or imaging characteristics, which c...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - October 22, 2019 Category: Endocrinology Source Type: research
Pheochromocytoma: An Approach To Diagnosis
Publication date: Available online 22 October 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Emilia Sbardella, Ashley B. GrossmanAbstractPheochromocytomas are rare neuroendocrine chromaffin-derived tumors that arise within the adrenal medulla. They are usually benign, but if not diagnosed or if left untreated, they can have devastating consequences. Clinical consideration of the diagnosis is paramount, as they may have protean manifestations, and a high index of suspicion is essential if serious consequences are to be avoided.An accurate biochemical diagnosis is crucial for the managemen...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - October 22, 2019 Category: Endocrinology Source Type: research
Editorial Board
Publication date: June 2019Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 33, Issue 3Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - October 9, 2019 Category: Endocrinology Source Type: research
