FATHER'S ABSENCE IN THE MONGOLIAN GERBIL (Meriones unguiculatus) IS ASSOCIATED WITH ALTERATIONS IN PATERNAL BEHAVIOR, T, CORT, PRESENCE OF ER α, AND AR IN mPOA/ BNST
Behav Brain Res. 2024 Mar 1:114928. doi: 10.1016/j.bbr.2024.114928. Online ahead of print.ABSTRACTTestosterone (T), estrogen receptor alpha (ERα), and androgen receptor (AR) play a significant role in the regulation of paternal behavior. We determined the effects of deprivation of paternal care on alterations in paternal behavior, T concentrations in plasma, and the presence of ERα and AR in the medial preoptic area (mPOA), bed nucleus of the stria terminalis (BNST), medial amygdala (MeA), and olfactory bulb (OB), as well as the corticosterone (CORT) concentrations in plasma caused by deprivation of paternal care in the ...
Source: Behavioural Brain Research - March 3, 2024 Category: Neurology Authors: Brenda Garc ía-Saucedo Luis Romero-Morales Carmen Álvarez-Rodriguez Ren é Cárdenas-Vázquez Mar ía Rosa Ávila-Costa Juana Luis Source Type: research
Electrophysiological indexes of ingroup bias in a group Stroop task: evidence from an event-related potential study
This study implied a novel direction to study the neural basis of ingroup bias by investigating the roles of ingroup bias in assigning attentional resources to group information.PMID:38432302 | DOI:10.1016/j.bbr.2024.114931 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 3, 2024 Category: Neurology Authors: Jiashan Sima Huanke Ma Fan Liu Chenjun Lou Feng Zou Yufeng Wang Yanyan Luo Meng Zhang Xin Wu Source Type: research
Quercetin attenuates brain apoptosis in mice with chronic unpredictable mild stress-induced depression
CONCLUSION: QUE could attenuate brain apoptosis in mice with CUMS-induced depression, and the mechanism may be related to the ERK/Nrf2 pathway, indicating that QUE could be a potential treatment for depression.PMID:38432303 | DOI:10.1016/j.bbr.2024.114934 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 3, 2024 Category: Neurology Authors: Chenjie Ge Shiliang Wang Xuqi Wu Lilei Lei Source Type: research
Neural Correlates of the Addictions Neuroclinical Assessment (ANA) Incentive Salience Factor Among Individuals with Alcohol Use Disorder
This study serves as a preliminary bio-behavioral validation for the incentive salience factor of the ANA. Further studies validating the neural correlates of other ANA factors, as well as replication in larger samples, appear warranted.PMID:38431152 | DOI:10.1016/j.bbr.2024.114926 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 2, 2024 Category: Neurology Authors: Steven J Nieto Erica N Grodin Lara A Ray Source Type: research
Neural Correlates of the Addictions Neuroclinical Assessment (ANA) Incentive Salience Factor Among Individuals with Alcohol Use Disorder
This study serves as a preliminary bio-behavioral validation for the incentive salience factor of the ANA. Further studies validating the neural correlates of other ANA factors, as well as replication in larger samples, appear warranted.PMID:38431152 | DOI:10.1016/j.bbr.2024.114926 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 2, 2024 Category: Neurology Authors: Steven J Nieto Erica N Grodin Lara A Ray Source Type: research
Genetic causal association between varicella-zoster virus infection and psychiatric disorders: A 2-sample Mendelian randomization study
CONCLUSIONS: Our findings provide compelling evidence of a causal effect of chickenpox on the risk of BD. To gain a more comprehensive understanding of this association and its underlying mechanisms, additional research is needed. Such investigations are pivotal in identifying effective interventions for promoting BD prevention.PMID:38428645 | DOI:10.1016/j.bbr.2024.114927 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 1, 2024 Category: Neurology Authors: Bo Yan Pan Liao Conglin Wang Zhaoli Han Fangyuan Cheng Ping Lei Source Type: research
Synergistic effects of citicoline and silymarin nanomicelles in restraint stress-exposed mice
CONCLUSION: The combination synergistically improved emotion-like behaviors, alleviating the inflammation and upregulating the hippocampal BDNF-mediated CREB signaling pathway.PMID:38428646 | DOI:10.1016/j.bbr.2024.114929 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 1, 2024 Category: Neurology Authors: Elham Shayan Fatemeh Maheri Fatemeh Aflaki Seyyedeh-Elaheh Mousavi Mohammad-Reza Zarrindast Nahid Fakhraei Seyyed-Mahdi Rezayat Sorkhabadi Seyed-Mohammad-Masoud Shushtarian Source Type: research
Genetic variation in endocannabinoid signaling: Anxiety, depression, and threat- and reward-related brain functioning during the transition into adolescence
CONCLUSIONS: Our findings add to emerging evidence linking the FAAH C385A variant to lower risk of psychopathology, and extend these findings to a developmental sample. In particular, we found lower depressive symptoms in FAAH AA genotypes compared to AC and CC genotypes. Future research is needed to characterize the role of the FAAH variant and the eCB system more broadly in neurodevelopment and psychiatric risk.PMID:38423255 | DOI:10.1016/j.bbr.2024.114925 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - February 29, 2024 Category: Neurology Authors: Shreya Desai Clara G Zundel Julia M Evanski Leah C Gowatch Amanpreet Bhogal Samantha Ely Carmen Carpenter MacKenna Shampine Emilie O'Mara Christine A Rabinak Hilary A Marusak Source Type: research
Exposure to the Psychedelic Substance 25H-NBOMe Disrupts Maternal Care in Lactating Rats and Subsequently Impairs the Social Play Behavior of the Offspring
Behav Brain Res. 2024 Feb 27:114924. doi: 10.1016/j.bbr.2024.114924. Online ahead of print.ABSTRACTGiven the critical role of maternal care in the neurodevelopment of offspring, this study aimed to investigate the effects of the psychedelic substance 25H-NBOMe on maternal behavior in lactating rats and its subsequent impact on the social and neurodevelopmental behavior of the offspring. We administered two different dosages of 25H-NBOMe (0.3mg/kg and 1.0mg/kg; i,p,) to lactating rats and observed changes in maternal behaviors, such as nest-building and pup retrieval, and in offspring behaviors, including social play. Behav...
Source: Behavioural Brain Research - February 29, 2024 Category: Neurology Authors: L ídia M Melo Wellington A de Barros Ângelo de Fátima Fabiana C Vilela Giusti Alexandre Giusti-Paiva Source Type: research
Genetic variation in endocannabinoid signaling: Anxiety, depression, and threat- and reward-related brain functioning during the transition into adolescence
CONCLUSIONS: Our findings add to emerging evidence linking the FAAH C385A variant to lower risk of psychopathology, and extend these findings to a developmental sample. In particular, we found lower depressive symptoms in FAAH AA genotypes compared to AC and CC genotypes. Future research is needed to characterize the role of the FAAH variant and the eCB system more broadly in neurodevelopment and psychiatric risk.PMID:38423255 | DOI:10.1016/j.bbr.2024.114925 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - February 29, 2024 Category: Neurology Authors: Shreya Desai Clara G Zundel Julia M Evanski Leah C Gowatch Amanpreet Bhogal Samantha Ely Carmen Carpenter MacKenna Shampine Emilie O'Mara Christine A Rabinak Hilary A Marusak Source Type: research
Exposure to the Psychedelic Substance 25H-NBOMe Disrupts Maternal Care in Lactating Rats and Subsequently Impairs the Social Play Behavior of the Offspring
Behav Brain Res. 2024 Feb 27:114924. doi: 10.1016/j.bbr.2024.114924. Online ahead of print.ABSTRACTGiven the critical role of maternal care in the neurodevelopment of offspring, this study aimed to investigate the effects of the psychedelic substance 25H-NBOMe on maternal behavior in lactating rats and its subsequent impact on the social and neurodevelopmental behavior of the offspring. We administered two different dosages of 25H-NBOMe (0.3mg/kg and 1.0mg/kg; i,p,) to lactating rats and observed changes in maternal behaviors, such as nest-building and pup retrieval, and in offspring behaviors, including social play. Behav...
Source: Behavioural Brain Research - February 29, 2024 Category: Neurology Authors: L ídia M Melo Wellington A de Barros Ângelo de Fátima Fabiana C Vilela Giusti Alexandre Giusti-Paiva Source Type: research
Age dependent path integration deficit in 5xFAD mice
Behav Brain Res. 2024 Feb 24;463:114919. doi: 10.1016/j.bbr.2024.114919. Online ahead of print.ABSTRACTAlzheimer's disease (AD) is a severe neurodegenerative disorder and the most common form of dementia in elderly individuals, characterized by memory deficits, cognitive decline, and neuropathology. The identification of preclinical markers for AD remains elusive. We employed an ultrasound-evoked spatial memory assay to investigate path integration (PI) in wild type C57BL/6 J and 5xFAD mice. We observed significant recruitment of the mammillary bodies (MB) and subiculum (Sub) - core regions of the Papez circuit during PI, ...
Source: Behavioural Brain Research - February 26, 2024 Category: Neurology Authors: Kendall D Mar Chanbee So Yixin Hou Jun Chul Kim Source Type: research
Exploring transgenerational inheritance in epigenotypes of DAT heterozygous rats: circadian anomalies and attentional vulnerability
Behav Brain Res. 2024 Feb 24:114921. doi: 10.1016/j.bbr.2024.114921. Online ahead of print.ABSTRACTDopamine (DA) is mainly involved in locomotor activity, reward processes and maternal behaviors. Rats with KO gene for dopamine transporter (DAT) coding for a truncated DAT protein are in hyperdopaminergic conditions and develop stereotyped behaviors and hyperactivity. Our aim was to test the prior transgenerational modulation of wild and truncated allele as expressed in heterozygous DAT rats: specifically we addressed the possible sequelae due to genotype and gender of the ancestors, with regard to behavioral differences in ...
Source: Behavioural Brain Research - February 26, 2024 Category: Neurology Authors: Concetto Puzzo Fabiana Festucci Giuseppe Curcio Antonella Gigantesco Walter Adriani Source Type: research
Effects of cortisol administration on heart rate variability and functional connectivity across women with different depression histories
Behav Brain Res. 2024 Feb 24;463:114923. doi: 10.1016/j.bbr.2024.114923. Online ahead of print.ABSTRACTAbnormalities within the hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system have been implicated in depression. Studies have reported glucocorticoid insensitivity and reduced heart rate variability (HRV) in depressive disorders. However, little is known about the effects of cortisol on HRV and resting-state functional connectivity (rsFC) of the central autonomic network (CAN) in depression. We collected resting-state fMRI and cardiac data for women with different depression histories (n = 61) after adm...
Source: Behavioural Brain Research - February 26, 2024 Category: Neurology Authors: Carissa L Philippi Emily Weible Alissa Ehlers Erin C Walsh Roxanne M Hoks Rasmus M Birn Heather C Abercrombie Source Type: research
The 5-HT2A, 5-HT5A, and 5-HT6 serotonergic receptors in the medial prefrontal cortex behave differently in extinction learning: Does social support play a role?
Behav Brain Res. 2024 Feb 24;463:114922. doi: 10.1016/j.bbr.2024.114922. Online ahead of print.ABSTRACTStudies on the social modulation of fear have revealed that in social species, individuals in a distressed state show better recovery from aversive experiences when accompanied - referred to as social buffering. However, the underlying mechanisms remain unknown, hindering the understanding of such an approach. Our previous data showed that the presence of a conspecific during the extinction task inhibited the retrieval of fear memory without affecting the extinction memory in the retention test. Here, we investigate the r...
Source: Behavioural Brain Research - February 26, 2024 Category: Neurology Authors: Clarissa Penha Farias Ana Karla Oliveira Leite Bianca Estefani Schmidt Jociane de Carvalho Myskiw Angela T S Wyse Source Type: research
