GPS tracking technology and re-visiting the relationship between the avian visual Wulst and homing pigeon navigation
Behav Brain Res. 2024 Mar 28;465:114971. doi: 10.1016/j.bbr.2024.114971. Online ahead of print.ABSTRACTWithin their familiar areas homing pigeons rely on familiar visual landscape features and landmarks for homing. However, the neural basis of visual landmark-based navigation has been so far investigated mainly in relation to the role of the hippocampal formation. The avian visual Wulst is the telencephalic projection field of the thalamofugal pathway that has been suggested to be involved in processing lateral visual inputs that originate from the far visual field. The Wulst is therefore a good candidate for a neural stru...
Source: Behavioural Brain Research - March 29, 2024 Category: Neurology Authors: Sara Cioccarelli Dimitri Giunchi Enrica Pollonara Giovanni Casini Verner P Bingman Anna Gagliardo Source Type: research
The hippocampal Salt-Inducible Kinase 2-CREB-Regulated Transcription Co-activator 1 system mediates the antidepressant actions of paroxetine in mice
Behav Brain Res. 2024 Mar 27:114972. doi: 10.1016/j.bbr.2024.114972. Online ahead of print.ABSTRACTThe hippocampal salt-inducible kinase 2 (SIK2)-CREB-regulated transcription co-activator 1 (CRTC1) system has been demonstrated to participate in not only the pathogenesis of depression but also the antidepressant mechanisms of several antidepressant medications including fluoxetine, paroxetine, and mirtazapine. Like fluoxetine, paroxetine is also a widely used selective serotonin (5-HT) reuptake inhibitor (SSRI). Recent studies have indicated that paroxetine also modulates several pharmacological targets other than the 5-HT ...
Source: Behavioural Brain Research - March 29, 2024 Category: Neurology Authors: Xiang-Ming Cai Xiao-Yu Sun Rui Li Pei-Juan Wang Jian-Cheng Qi Yu-Xin Ge Lei Yang Source Type: research
Neonatal nociceptive stimulation results in pain sensitization, reduction of hippocampal 5-HT < sub > 1A < /sub > receptor, and p-CREB expression in adult female rats
This study shows sex- and age-specific responses of signaling pathways within the hippocampus accompanied by altered behavioral repertoire, at long-term after neonatal painful stimulation.PMID:38552745 | DOI:10.1016/j.bbr.2024.114975 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 29, 2024 Category: Neurology Authors: Jackeline Malheiros Cristiane Amaral Luiz Severino da Silva Ruth Guinsburg Luciene Covolan Source Type: research
GPS Tracking Technology and Re-visiting the Relationship between the Avian Visual Wulst and Homing Pigeon Navigation
Behav Brain Res. 2024 Mar 27:114971. doi: 10.1016/j.bbr.2024.114971. Online ahead of print.ABSTRACTWithin their familiar areas homing pigeons rely on familiar visual landscape features and landmarks for homing. However, the neural basis of visual landmark-based navigation has been so far investigated mainly in relation to the role of the hippocampal formation. The avian visual Wulst is the telencephalic projection field of the thalamofugal pathway that has been suggested to be involved in processing lateral visual inputs that originate from the far visual field. The Wulst is therefore a good candidate for a neural structur...
Source: Behavioural Brain Research - March 29, 2024 Category: Neurology Authors: Sara Cioccarelli Dimitri Giunchi Enrica Pollonara Giovanni Casini Verner P Bingman Anna Gagliardo Source Type: research
The hippocampal Salt-Inducible Kinase 2-CREB-Regulated Transcription Co-activator 1 system mediates the antidepressant actions of paroxetine in mice
Behav Brain Res. 2024 Mar 27:114972. doi: 10.1016/j.bbr.2024.114972. Online ahead of print.ABSTRACTThe hippocampal salt-inducible kinase 2 (SIK2)-CREB-regulated transcription co-activator 1 (CRTC1) system has been demonstrated to participate in not only the pathogenesis of depression but also the antidepressant mechanisms of several antidepressant medications including fluoxetine, paroxetine, and mirtazapine. Like fluoxetine, paroxetine is also a widely used selective serotonin (5-HT) reuptake inhibitor (SSRI). Recent studies have indicated that paroxetine also modulates several pharmacological targets other than the 5-HT ...
Source: Behavioural Brain Research - March 29, 2024 Category: Neurology Authors: Xiang-Ming Cai Xiao-Yu Sun Rui Li Pei-Juan Wang Jian-Cheng Qi Yu-Xin Ge Lei Yang Source Type: research
Neonatal nociceptive stimulation results in pain sensitization, reduction of hippocampal 5-HT < sub > 1A < /sub > receptor, and p-CREB expression in adult female rats
This study shows sex- and age-specific responses of signaling pathways within the hippocampus accompanied by altered behavioral repertoire, at long-term after neonatal painful stimulation.PMID:38552745 | DOI:10.1016/j.bbr.2024.114975 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 29, 2024 Category: Neurology Authors: Jackeline Malheiros Cristiane Amaral Luiz Severino da Silva Ruth Guinsburg Luciene Covolan Source Type: research
The Protective Role of Sesame Oil against Parkinson's-Like Disease Induced by Manganese in Rats
In conclusion, SO may provide potential therapeutic benefits in enhancing motor performance and promoting neuronal survival in individuals highly exposed to Mn.PMID:38548024 | DOI:10.1016/j.bbr.2024.114969 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 28, 2024 Category: Neurology Authors: Wedad S Sarawi Hala A Attia Hatun A Alomar Rawan Alhaidar Esraa Rihan Nora Aldurgham Rehab A Ali Source Type: research
The Protective Role of Sesame Oil against Parkinson's-Like Disease Induced by Manganese in Rats
In conclusion, SO may provide potential therapeutic benefits in enhancing motor performance and promoting neuronal survival in individuals highly exposed to Mn.PMID:38548024 | DOI:10.1016/j.bbr.2024.114969 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - March 28, 2024 Category: Neurology Authors: Wedad S Sarawi Hala A Attia Hatun A Alomar Rawan Alhaidar Esraa Rihan Nora Aldurgham Rehab A Ali Source Type: research
Age-related changes in species-typical behaviours in the 5xFAD mouse model of Alzheimer's disease from 4-16 months of age
Behav Brain Res. 2024 Mar 24:114970. doi: 10.1016/j.bbr.2024.114970. Online ahead of print.ABSTRACTAlzheimer's disease (AD) patients show age-related decreases in the ability to perform activities of daily living and the decline in these activities is related to the severity of neurobiological deterioration underlying the disease. The 5xFAD mouse model of AD shows age-related impairments in sensory- motor and cognitive function, but little is known about changes in species-typical behaviours that may model activities of daily living in AD patients. Therefore, we examined species-typical behaviours used as indices of explor...
Source: Behavioural Brain Research - March 26, 2024 Category: Neurology Authors: Timothy P O'Leary Richard E Brown Source Type: research
Age-related changes in species-typical behaviours in the 5xFAD mouse model of Alzheimer's disease from 4-16 months of age
Behav Brain Res. 2024 Mar 24:114970. doi: 10.1016/j.bbr.2024.114970. Online ahead of print.ABSTRACTAlzheimer's disease (AD) patients show age-related decreases in the ability to perform activities of daily living and the decline in these activities is related to the severity of neurobiological deterioration underlying the disease. The 5xFAD mouse model of AD shows age-related impairments in sensory- motor and cognitive function, but little is known about changes in species-typical behaviours that may model activities of daily living in AD patients. Therefore, we examined species-typical behaviours used as indices of explor...
Source: Behavioural Brain Research - March 26, 2024 Category: Neurology Authors: Timothy P O'Leary Richard E Brown Source Type: research
Socially-mediated activation in the snake social-decision-making network
Behav Brain Res. 2024 Mar 22:114965. doi: 10.1016/j.bbr.2024.114965. Online ahead of print.ABSTRACTBrain areas important for social perception, social reward, and social behavior - collectively referred to as the social-decision-making network (SDN) - appear to be highly conserved across taxa. These brain areas facilitate a variety of social behaviors such as conspecific approach/avoidance, aggression, mating, parental care, and recognition. Although the SDN has been investigated across taxa, little is known about its functioning in reptiles. Research on the snake SDN may provide important new insights, as snakes have a ke...
Source: Behavioural Brain Research - March 24, 2024 Category: Neurology Authors: Morgan Skinner Dania Daanish Chelsey Damphousse Randolph W Krohmer Paul Mallet Bruce McKay Noam Miller Source Type: research
Histamine and Receptors in Neuroinflammation: Their Roles on neurodegenerative diseases
Behav Brain Res. 2024 Mar 22:114964. doi: 10.1016/j.bbr.2024.114964. Online ahead of print.ABSTRACTHistamine, an auto-reactive substance and mediator of inflammation, is synthesized from histidine through the action of histidine decarboxylase (HDC). It primarily acts on histamine receptors in the central nervous system (CNS). Increasing evidence suggests that histamine and its receptors play a crucial role in neuroinflammation, thereby modulating the pathology of neurodegenerative diseases. Recent studies have demonstrated that histamine regulates the phenotypic switching of microglia and astrocytes, inhibits the productio...
Source: Behavioural Brain Research - March 24, 2024 Category: Neurology Authors: Zhenyu Zhou Qi An Wanying Zhang Yixin Li Qihang Zhang Haijing Yan Source Type: research
Socially-mediated activation in the snake social-decision-making network
Behav Brain Res. 2024 Mar 22:114965. doi: 10.1016/j.bbr.2024.114965. Online ahead of print.ABSTRACTBrain areas important for social perception, social reward, and social behavior - collectively referred to as the social-decision-making network (SDN) - appear to be highly conserved across taxa. These brain areas facilitate a variety of social behaviors such as conspecific approach/avoidance, aggression, mating, parental care, and recognition. Although the SDN has been investigated across taxa, little is known about its functioning in reptiles. Research on the snake SDN may provide important new insights, as snakes have a ke...
Source: Behavioural Brain Research - March 24, 2024 Category: Neurology Authors: Morgan Skinner Dania Daanish Chelsey Damphousse Randolph W Krohmer Paul Mallet Bruce McKay Noam Miller Source Type: research
Histamine and Receptors in Neuroinflammation: Their Roles on neurodegenerative diseases
Behav Brain Res. 2024 Mar 22:114964. doi: 10.1016/j.bbr.2024.114964. Online ahead of print.ABSTRACTHistamine, an auto-reactive substance and mediator of inflammation, is synthesized from histidine through the action of histidine decarboxylase (HDC). It primarily acts on histamine receptors in the central nervous system (CNS). Increasing evidence suggests that histamine and its receptors play a crucial role in neuroinflammation, thereby modulating the pathology of neurodegenerative diseases. Recent studies have demonstrated that histamine regulates the phenotypic switching of microglia and astrocytes, inhibits the productio...
Source: Behavioural Brain Research - March 24, 2024 Category: Neurology Authors: Zhenyu Zhou Qi An Wanying Zhang Yixin Li Qihang Zhang Haijing Yan Source Type: research
Socially-mediated activation in the snake social-decision-making network
Behav Brain Res. 2024 Mar 22:114965. doi: 10.1016/j.bbr.2024.114965. Online ahead of print.ABSTRACTBrain areas important for social perception, social reward, and social behavior - collectively referred to as the social-decision-making network (SDN) - appear to be highly conserved across taxa. These brain areas facilitate a variety of social behaviors such as conspecific approach/avoidance, aggression, mating, parental care, and recognition. Although the SDN has been investigated across taxa, little is known about its functioning in reptiles. Research on the snake SDN may provide important new insights, as snakes have a ke...
Source: Behavioural Brain Research - March 24, 2024 Category: Neurology Authors: Morgan Skinner Dania Daanish Chelsey Damphousse Randolph W Krohmer Paul Mallet Bruce McKay Noam Miller Source Type: research
