Task-general or specific: The alertness modulates post-error adjustment
This study applied the Attentional Networks Test and the Four-choice Flanker task with three response stimulus intervals (RSIs) to explore the correlation between alertness and post-error adjustment. The linear mixed-effects model of alertness and RSI on the post-error processing indicators showed a significant negative correlation between the alertness and post-error slowing (PES) under 200ms RSI and post-error improvement in accuracy (PIA) under 700ms RSI and 1200ms RSI. Participants with lower alertness showed larger post-error slowing in the early stages, while those with higher alertness had smaller PIA in later stage...
Source: Behavioural Brain Research - April 6, 2024 Category: Neurology Authors: Na Hu Quanshan Long Lijun Wang Xueping Hu Xiaoxi Wang Ruimin Ma Yuqing Bai Chen Qian Antao Chen Source Type: research
Creatine supplementation research fails to support the theoretical basis for an effect on cognition: Evidence from a systematic review
Behav Brain Res. 2024 Apr 4;466:114982. doi: 10.1016/j.bbr.2024.114982. Online ahead of print.ABSTRACTCreatine supplementation has been put forward as a possible aid to cognition, particularly for vegans, vegetarians, the elderly, sleep deprived and hypoxic individuals. However, previous narrative reviews have only provided limited support for these claims. This is despite the fact that research has shown that creatine supplementation can induce increased brain concentrations of creatine, albeit to a limited extent. We carried out a systematic review to examine the current state of affairs. The review supported claims that...
Source: Behavioural Brain Research - April 6, 2024 Category: Neurology Authors: Terry McMorris Beverley J Hale Beatrice S Pine Thomas B Williams Source Type: research
Berberine and hesperidin prevent the memory consolidation impairment induced by pentylenotetrazole in zebrafish
This study verified the effects of the natural compounds berberine and hesperidin on seizure development and cognitive impairment triggered by pentylenetetrazole (PTZ) in zebrafish. Adult animals were submitted to a training session in the inhibitory avoidance test and, after 10minutes, they received an intraperitoneal injection of 25, 50, or 100mg/kg berberine or 100 or 200mg/kg hesperidin. After 30minutes, the animals were exposed to 7.5mM PTZ for 10minutes. Animals were submitted to the test session 24h after the training session to verify their cognitive performance. Zebrafish larvae were exposed to 100µM or 500µM be...
Source: Behavioural Brain Research - April 5, 2024 Category: Neurology Authors: Kanandra Taisa Bertoncello Gabriel Rodrigues Carla Denise Bonan Source Type: research
Vulnerable at rest? A resting-state EEG study and psycho-social factors of young adult offspring of alcohol-dependent parents
CONCLUSIONS: This study does not provide evidence suggesting vulnerability in offspring based on differences in spontaneous brain activity. Moreover, this investigation highlights the importance of interventions aimed at enhancing social connections in offspring. Such interventions can not only reduce the risk of developing AUD, given its strong association with increased feelings of loneliness but also improve the overall well-being of the offspring.PMID:38580199 | DOI:10.1016/j.bbr.2024.114980 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - April 5, 2024 Category: Neurology Authors: Milagros Rubio Ana Sion Isabel Dom ínguez Centeno Daniel Maldonado S ánchez Gabriel Rubio Maartje Luijten Rosa Jurado Barba Source Type: research
Neurophysiological Analysis of Disadvantageous Social Inequity: Exploring Emotional Behavior Changes and c-Fos Expression in a Male Rat Model
In this study, we developed a rat model to determine the effects of socially equal or unequal reward and stress on emotional changes in male rats. During the training session, the rats were trained to escape when a sound cue was presented, and they were assigned to one of the following groups: all escaping rats [advantageous equity (AE)], freely moving rats alongside a restrained rat [advantageous inequity (AI)], all restrained rats [disadvantageous equity (DE)], and a rat restrained in the presence of freely moving companions [disadvantageous inequity (DI)]. During the test session, rats in the advantageous group (AE and ...
Source: Behavioural Brain Research - April 5, 2024 Category: Neurology Authors: Yujeong Jeong Jihyun Noh Source Type: research
Berberine and hesperidin prevent the memory consolidation impairment induced by pentylenotetrazole in zebrafish
This study verified the effects of the natural compounds berberine and hesperidin on seizure development and cognitive impairment triggered by pentylenetetrazole (PTZ) in zebrafish. Adult animals were submitted to a training session in the inhibitory avoidance test and, after 10minutes, they received an intraperitoneal injection of 25, 50, or 100mg/kg berberine or 100 or 200mg/kg hesperidin. After 30minutes, the animals were exposed to 7.5mM PTZ for 10minutes. Animals were submitted to the test session 24h after the training session to verify their cognitive performance. Zebrafish larvae were exposed to 100µM or 500µM be...
Source: Behavioural Brain Research - April 5, 2024 Category: Neurology Authors: Kanandra Taisa Bertoncello Gabriel Rodrigues Carla Denise Bonan Source Type: research
Vulnerable at rest? A resting-state EEG study and psycho-social factors of young adult offspring of alcohol-dependent parents
CONCLUSIONS: This study does not provide evidence suggesting vulnerability in offspring based on differences in spontaneous brain activity. Moreover, this investigation highlights the importance of interventions aimed at enhancing social connections in offspring. Such interventions can not only reduce the risk of developing AUD, given its strong association with increased feelings of loneliness but also improve the overall well-being of the offspring.PMID:38580199 | DOI:10.1016/j.bbr.2024.114980 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - April 5, 2024 Category: Neurology Authors: Milagros Rubio Ana Sion Isabel Dom ínguez Centeno Daniel Maldonado S ánchez Gabriel Rubio Maartje Luijten Rosa Jurado Barba Source Type: research
Neurophysiological Analysis of Disadvantageous Social Inequity: Exploring Emotional Behavior Changes and c-Fos Expression in a Male Rat Model
In this study, we developed a rat model to determine the effects of socially equal or unequal reward and stress on emotional changes in male rats. During the training session, the rats were trained to escape when a sound cue was presented, and they were assigned to one of the following groups: all escaping rats [advantageous equity (AE)], freely moving rats alongside a restrained rat [advantageous inequity (AI)], all restrained rats [disadvantageous equity (DE)], and a rat restrained in the presence of freely moving companions [disadvantageous inequity (DI)]. During the test session, rats in the advantageous group (AE and ...
Source: Behavioural Brain Research - April 5, 2024 Category: Neurology Authors: Yujeong Jeong Jihyun Noh Source Type: research
Characterisation of behaviours relevant to apathy syndrome in the aged male rat
Behav Brain Res. 2024 Apr 1:114977. doi: 10.1016/j.bbr.2024.114977. Online ahead of print.ABSTRACTApathy is a complex psychiatric syndrome characterised by motivational deficit, emotional blunting and cognitive changes. It occurs alongside a broad range of neurological disorders, but also occurs in otherwise healthy ageing. Despite its clinical prevalence, apathy does not yet have a designated treatment strategy. Generation of a translational animal model of apathy syndrome would facilitate the development of novel treatments. Given the multidimensional nature of apathy, a model cannot be achieved with a single behavioural...
Source: Behavioural Brain Research - April 3, 2024 Category: Neurology Authors: Megan G Jackson Stafford L Lightman Emma S J Robinson Source Type: research
Characterisation of behaviours relevant to apathy syndrome in the aged male rat
Behav Brain Res. 2024 Apr 1:114977. doi: 10.1016/j.bbr.2024.114977. Online ahead of print.ABSTRACTApathy is a complex psychiatric syndrome characterised by motivational deficit, emotional blunting and cognitive changes. It occurs alongside a broad range of neurological disorders, but also occurs in otherwise healthy ageing. Despite its clinical prevalence, apathy does not yet have a designated treatment strategy. Generation of a translational animal model of apathy syndrome would facilitate the development of novel treatments. Given the multidimensional nature of apathy, a model cannot be achieved with a single behavioural...
Source: Behavioural Brain Research - April 3, 2024 Category: Neurology Authors: Megan G Jackson Stafford L Lightman Emma S J Robinson Source Type: research
Characterisation of behaviours relevant to apathy syndrome in the aged male rat
Behav Brain Res. 2024 Apr 1:114977. doi: 10.1016/j.bbr.2024.114977. Online ahead of print.ABSTRACTApathy is a complex psychiatric syndrome characterised by motivational deficit, emotional blunting and cognitive changes. It occurs alongside a broad range of neurological disorders, but also occurs in otherwise healthy ageing. Despite its clinical prevalence, apathy does not yet have a designated treatment strategy. Generation of a translational animal model of apathy syndrome would facilitate the development of novel treatments. Given the multidimensional nature of apathy, a model cannot be achieved with a single behavioural...
Source: Behavioural Brain Research - April 3, 2024 Category: Neurology Authors: Megan G Jackson Stafford L Lightman Emma S J Robinson Source Type: research
Reducing younger and older adults' spatial disorientation during indoor-outdoor transitions: Effects of route alignment and visual access on wayfinding
Behav Brain Res. 2024 Mar 29;465:114967. doi: 10.1016/j.bbr.2024.114967. Online ahead of print.ABSTRACTGetting lost could lead to frustration, anxiety, and even fatal accidents. Previous research primarily focused on disorientation in indoor or outdoor environments separately. The indoor-outdoor transition received little attention, yet it is in this complex transition that individuals often lose their way. Therefore, the effects of indoor-outdoor route alignment, visual access, and age on wayfinding performance and spatial cognition were examined. Twenty older adults (aged 18-25) and twenty young adults (aged 65-82) parti...
Source: Behavioural Brain Research - March 31, 2024 Category: Neurology Authors: Yanling Zuo Jia Zhou Source Type: research
Reducing Younger and Older Adults' Spatial Disorientation during Indoor-Outdoor Transitions: Effects of Route Alignment and Visual Access on Wayfinding
Behav Brain Res. 2024 Mar 29:114967. doi: 10.1016/j.bbr.2024.114967. Online ahead of print.ABSTRACTGetting lost could lead to frustration, anxiety, and even fatal accidents. Previous research primarily focused on disorientation in indoor or outdoor environments separately. The indoor-outdoor transition received little attention, yet it is in this complex transition that individuals often lose their way. Therefore, the effects of indoor-outdoor route alignment, visual access, and age on wayfinding performance and spatial cognition were examined. Twenty older adults (aged 18-25) and twenty young adults (aged 65-82) participa...
Source: Behavioural Brain Research - March 31, 2024 Category: Neurology Authors: Yanling Zuo Jia Zhou Source Type: research
Reducing Younger and Older Adults' Spatial Disorientation during Indoor-Outdoor Transitions: Effects of Route Alignment and Visual Access on Wayfinding
Behav Brain Res. 2024 Mar 29:114967. doi: 10.1016/j.bbr.2024.114967. Online ahead of print.ABSTRACTGetting lost could lead to frustration, anxiety, and even fatal accidents. Previous research primarily focused on disorientation in indoor or outdoor environments separately. The indoor-outdoor transition received little attention, yet it is in this complex transition that individuals often lose their way. Therefore, the effects of indoor-outdoor route alignment, visual access, and age on wayfinding performance and spatial cognition were examined. Twenty older adults (aged 18-25) and twenty young adults (aged 65-82) participa...
Source: Behavioural Brain Research - March 31, 2024 Category: Neurology Authors: Yanling Zuo Jia Zhou Source Type: research
Tenuifolin improves learning and memory by regulating long-term potentiation and dendritic structure of hippocampal CA1 area in healthy female mice but not male mice
Behav Brain Res. 2024 Mar 28:114974. doi: 10.1016/j.bbr.2024.114974. Online ahead of print.ABSTRACTPolygala tenuifolia Wild is an ancient traditional Chinese medicine. Its main component, tenuifolin (TEN), has been proven to improve cognitive impairment caused by neurodegenerative diseases and ovariectomy. However, there was hardly any pharmacological research about TEN and its potential gender differences. Considering the reduction of TEN on learning and memory dysfunction in ovariectomized animals, therefore, we focused on the impact of TEN in different mice genders in the current study. Spontaneous alternation behavior ...
Source: Behavioural Brain Research - March 30, 2024 Category: Neurology Authors: Heng Kong Yuan-Yuan Han Gai-Ling Yang Kang Li Lu Yu Xun-Kai Xie Guang-Yuan Xia Peng-Ju Wei Wan-Rong Zhang Chu-Hua Li Source Type: research
