Loneliness during the Post-Confinement Period: The Significance of Social Living Conditions for Stress Biomarkers and Memory
This study explored the repercussions of post-lockdown social restrictions across psychological (loneliness, perceived stress, and depressive symptoms), biological (hair cortisol and cardiovascular activity), and cognitive dimensions (subjective memory complaints and working, declarative, and prospective memory), with a specific emphasis on perceived loneliness and the living situation. The study included 45 students: 23 (mean age = 25.69 years) in the Alone Group (AG), who experienced significant family changes and international relocation, and 22 (mean age = 25.50 years) in the Not Alone Group (NAG), who maintained their...
Source: Behavioural Brain Research - November 24, 2023 Category: Neurology Authors: Daniela Batallas Valerie Rodr íguez Vanesa Hidalgo Alicia Salvador Source Type: research

A novel investigation of placebo analgesia through social communication in mice
CONCLUSIONS: To our knowledge, this is the first investigation of placebo analgesia without direct conditioning, instead relying on social communication between mice. The lack of effect with naloxone pretreatment suggests an opioid-independent effect in the Bystander mice. Placebo analgesia in mice may be possible without direct conditioning to better model the effect of expectation of a novel analgesic in humans.PMID:38000532 | DOI:10.1016/j.bbr.2023.114773 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - November 24, 2023 Category: Neurology Authors: Stacie K Totsch Robert E Sorge Source Type: research

Loneliness during the Post-Confinement Period: The Significance of Social Living Conditions for Stress Biomarkers and Memory
This study explored the repercussions of post-lockdown social restrictions across psychological (loneliness, perceived stress, and depressive symptoms), biological (hair cortisol and cardiovascular activity), and cognitive dimensions (subjective memory complaints and working, declarative, and prospective memory), with a specific emphasis on perceived loneliness and the living situation. The study included 45 students: 23 (mean age = 25.69 years) in the Alone Group (AG), who experienced significant family changes and international relocation, and 22 (mean age = 25.50 years) in the Not Alone Group (NAG), who maintained their...
Source: Behavioural Brain Research - November 24, 2023 Category: Neurology Authors: Daniela Batallas Valerie Rodr íguez Vanesa Hidalgo Alicia Salvador Source Type: research

A novel investigation of placebo analgesia through social communication in mice
CONCLUSIONS: To our knowledge, this is the first investigation of placebo analgesia without direct conditioning, instead relying on social communication between mice. The lack of effect with naloxone pretreatment suggests an opioid-independent effect in the Bystander mice. Placebo analgesia in mice may be possible without direct conditioning to better model the effect of expectation of a novel analgesic in humans.PMID:38000532 | DOI:10.1016/j.bbr.2023.114773 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - November 24, 2023 Category: Neurology Authors: Stacie K Totsch Robert E Sorge Source Type: research

Orexin receptors in the hippocampal dentate gyrus modulated the restraint stress-induced analgesia in the animal model of chronic pain
Behav Brain Res. 2023 Nov 22;459:114772. doi: 10.1016/j.bbr.2023.114772. Online ahead of print.ABSTRACTPrevious studies have shown that stressful stimuli induced an adaptive response of reduced nociception, known as stress-induced analgesia (SIA). Since orexin neuropeptides are involved in pain modulation, and orexin neurons, primarily located in the lateral hypothalamus (LH), project to various hippocampal regions, such as the dentate gyrus (DG), the current study aimed to examine the role of orexin receptors within the DG region in the restraint SIA in the animal model of chronic pain. One hundred-thirty adult male Wista...
Source: Behavioural Brain Research - November 23, 2023 Category: Neurology Authors: Matin Baghani Arad Bolouri-Roudsari Reyhaneh Askari Abbas Haghparast Source Type: research

Orexin receptors in the hippocampal dentate gyrus modulated the restraint stress-induced analgesia in the animal model of chronic pain
Behav Brain Res. 2023 Nov 21:114772. doi: 10.1016/j.bbr.2023.114772. Online ahead of print.ABSTRACTPrevious studies have shown that stressful stimuli induced an adaptive response of reduced nociception, known as stress-induced analgesia (SIA). Since orexin neuropeptides are involved in pain modulation, and orexin neurons, primarily located in the lateral hypothalamus (LH), project to various hippocampal regions, such as the dentate gyrus (DG), the current study aimed to examine the role of orexin receptors within the DG region in the restraint SIA in the animal model of chronic pain. One hundred-thirty adult male Wistar ra...
Source: Behavioural Brain Research - November 23, 2023 Category: Neurology Authors: Matin Baghani Arad Bolouri-Roudsari Reyhaneh Askari Abbas Haghparast Source Type: research

Coordination Function Index: A Novel Indicator for Assessing Hindlimb Locomotor Recovery in Spinal Cord Injury Rats Based on Catwalk Gait Parameters
In conclusion, we developed a systematic assessment indicator utilizing multiple CatWalk parameters to objectively evaluate hindlimb motor function recovery in rats after thoracic contusion SCI.PMID:37992973 | DOI:10.1016/j.bbr.2023.114765 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - November 22, 2023 Category: Neurology Authors: Song Liu Qiang Wu Liyue Wang Cong Xing Junrui Guo Baicao Li Hongpeng Ma Hao Zhong Mi Zhou Shibo Zhu Rusen Zhu Guangzhi Ning Source Type: research

Coordination Function Index: A Novel Indicator for Assessing Hindlimb Locomotor Recovery in Spinal Cord Injury Rats Based on Catwalk Gait Parameters
In conclusion, we developed a systematic assessment indicator utilizing multiple CatWalk parameters to objectively evaluate hindlimb motor function recovery in rats after thoracic contusion SCI.PMID:37992973 | DOI:10.1016/j.bbr.2023.114765 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - November 22, 2023 Category: Neurology Authors: Song Liu Qiang Wu Liyue Wang Cong Xing Junrui Guo Baicao Li Hongpeng Ma Hao Zhong Mi Zhou Shibo Zhu Rusen Zhu Guangzhi Ning Source Type: research

Obsessive-compulsive and perseverative behaviors in Huntington's disease
Behav Brain Res. 2023 Nov 19;458:114767. doi: 10.1016/j.bbr.2023.114767. Online ahead of print.ABSTRACTObsessive-compulsive and perseverative behaviors (OCBs/PBs) are characteristic features of Huntington's Disease (HD). Although a few recent research have attempted to discriminate between OCBs and PBs, most of the available evidence on OCBs does not consistently make this distinction. In this article, we aimed to explore the current inconsistencies in assessing and reporting OCBs/PBs and map the body of existing evidence. Up to half of the patients with motor manifest HD can experience OCBs. Separate reporting of PBs in H...
Source: Behavioural Brain Research - November 20, 2023 Category: Neurology Authors: Shayan Abdollah Zadegan Luke Kupcha Jorge Patino Natalia Pessoa Rocha Antonio L Teixeira Erin Furr Stimming Source Type: research

Role of Nucleus Accumbens D1-type Medium Spiny Neurons in the Expression and Extinction of Sign-tracking
Behav Brain Res. 2023 Nov 18:114768. doi: 10.1016/j.bbr.2023.114768. Online ahead of print.ABSTRACTWhile sign-tracking, also known as autoshaping, has been studied for many decades, only recently has the tendency to show sign-tracking behavior been linked to the development and persistence of addiction. Sign-tracking is dependent upon dopamine activity in the Nucleus Accumbens (NAc). The NAc is comprised predominantly of medium spiny projection neurons (MSN) that can be differentiated by their D1-like or D2-like dopamine receptor expression. Here we determined how reducing activity of D1-type MSNs in the NAc affects the ex...
Source: Behavioural Brain Research - November 20, 2023 Category: Neurology Authors: Rifka C Derman Elizabeth C Bryda Carrie R Ferrario Source Type: research

Transcranial alternating current stimulation does not affect microscale learning
Behav Brain Res. 2023 Nov 18:114770. doi: 10.1016/j.bbr.2023.114770. Online ahead of print.ABSTRACTA theory has been posited that microscale learning, which involves short intervals of a few seconds during explicit motor skill learning, considerably enhances performance. This phenomenon correlates with diminished beta-band activity in the frontal and parietal regions. However, there is a lack of neurophysiological studies regarding the relationship between microscale learning and implicit motor skill learning. In the present study, we aimed to determine the effects of transcranial alternating current stimulation (tACS) dur...
Source: Behavioural Brain Research - November 20, 2023 Category: Neurology Authors: Kyosuke Shiga Shota Miyaguchi Yasuto Inukai Naofumi Otsuru Hideaki Onishi Source Type: research

Dynamic analysis of amplitude of low-frequency fluctuation in children with growth hormone deficiency
CONCLUSION: The dALFF can capture dynamic changes in brain spontaneous activity, which are related to behavior and cognition. Based on this dynamic local brain activity, the results of this study provide a better understanding of the pathophysiological mechanism in children with GHD.PMID:37984523 | DOI:10.1016/j.bbr.2023.114769 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - November 20, 2023 Category: Neurology Authors: Jurong Ding Qiang Chen Yihong Liu Zhiling Tang Chenyu Feng Mei Wang Zhongxiang Ding Source Type: research

Obsessive-Compulsive and Perseverative Behaviors in Huntington's Disease
Behav Brain Res. 2023 Nov 18:114767. doi: 10.1016/j.bbr.2023.114767. Online ahead of print.ABSTRACTObsessive-compulsive and perseverative behaviors (OCBs/PBs) are characteristic features of Huntington's Disease (HD). Although a few recent research have attempted to discriminate between OCBs and PBs, most of the available evidence on OCBs does not consistently make this distinction. In this article, we aimed to explore the current inconsistencies in assessing and reporting OCBs/PBs and map the body of existing evidence. Up to half of the patients with motor manifest HD can experience OCBs. Separate reporting of PBs in HD pa...
Source: Behavioural Brain Research - November 20, 2023 Category: Neurology Authors: Shayan Abdollah Zadegan Luke Kupcha Jorge Patino Natalia Pessoa Rocha Antonio L Teixeira Erin Furr Stimming Source Type: research

Role of Nucleus Accumbens D1-type Medium Spiny Neurons in the Expression and Extinction of Sign-tracking
Behav Brain Res. 2023 Nov 18:114768. doi: 10.1016/j.bbr.2023.114768. Online ahead of print.ABSTRACTWhile sign-tracking, also known as autoshaping, has been studied for many decades, only recently has the tendency to show sign-tracking behavior been linked to the development and persistence of addiction. Sign-tracking is dependent upon dopamine activity in the Nucleus Accumbens (NAc). The NAc is comprised predominantly of medium spiny projection neurons (MSN) that can be differentiated by their D1-like or D2-like dopamine receptor expression. Here we determined how reducing activity of D1-type MSNs in the NAc affects the ex...
Source: Behavioural Brain Research - November 20, 2023 Category: Neurology Authors: Rifka C Derman Elizabeth C Bryda Carrie R Ferrario Source Type: research

Transcranial alternating current stimulation does not affect microscale learning
Behav Brain Res. 2023 Nov 18:114770. doi: 10.1016/j.bbr.2023.114770. Online ahead of print.ABSTRACTA theory has been posited that microscale learning, which involves short intervals of a few seconds during explicit motor skill learning, considerably enhances performance. This phenomenon correlates with diminished beta-band activity in the frontal and parietal regions. However, there is a lack of neurophysiological studies regarding the relationship between microscale learning and implicit motor skill learning. In the present study, we aimed to determine the effects of transcranial alternating current stimulation (tACS) dur...
Source: Behavioural Brain Research - November 20, 2023 Category: Neurology Authors: Kyosuke Shiga Shota Miyaguchi Yasuto Inukai Naofumi Otsuru Hideaki Onishi Source Type: research