Standardization of knowledge-based volumetric modulated arc therapy planning with a multi-institution model (broad model) to improve prostate cancer treatment quality
Conclusions: KBP with the broad model is clinically effective and applicable as a standardization method at multiple institutions. (Source: Australasian Physical and Engineering Sciences in Medicine)
Source: Australasian Physical and Engineering Sciences in Medicine - September 1, 2023 Category: Biomedical Engineering Source Type: research

Weighted ordinal connection based functional network classification for schizophrenia disease detection using EEG signal
AbstractA brain connectivity network (BCN) is an advanced approach to examining brain functionality in various conditions. However, the predictability of the BCN is affected by the connectivity measure used for the network construction. Various connectivity measures available in the literature differ according to the domain of their working data. The application of random connectivity measures might result in an inefficient BCN that ultimately hampers its predictability. Therefore, selecting an appropriate functional connectivity metric is crucial in clinical as well as cognitive neuroscience. In parallel to this, an effec...
Source: Australasian Physical and Engineering Sciences in Medicine - September 1, 2023 Category: Biomedical Engineering Source Type: research

Facial functional networks during resting state revealed by thermal infrared imaging
AbstractIn recent decades, an increasing number of studies on psychophysiology and, in general, on clinical medicine has employed the technique of facial thermal infrared imaging (IRI), which allows to obtain information about the emotional and physical states of the subjects in a completely non-invasive and contactless fashion. Several regions of interest (ROIs) have been reported in literature as salient areas for the psychophysiological characterization of a subject (i.e. nose tip and glabella ROIs). There is however a lack of studies focusing on the functional correlation among these ROIs and about the physiological ba...
Source: Australasian Physical and Engineering Sciences in Medicine - August 29, 2023 Category: Biomedical Engineering Source Type: research

Weight-bearing cone-beam CT with extensive coverage for volumetric imaging in adolescent idiopathic scoliosis: system implementation and initial validation
AbstractThe study aimed to introduce a novel imaging method that generates large-coverage, weight-bearing, and 3D images of the whole spine. The proposed system comprises an X-ray tube, a flat panel detector, and a standing platform. The standing platform rotates the imaged subject, allowing for the acquisition of serial fluoroscopic images from different angles which can be used to create 3D images. To increase the longitudinal coverage, we apply a segmental scanning pattern in which the imaged region is scanned in segments and stitched. To address the issue of data inaccuracy between the segments, redundant areas are set...
Source: Australasian Physical and Engineering Sciences in Medicine - August 29, 2023 Category: Biomedical Engineering Source Type: research

Nonlinear fourth-order elastic characterization of the cornea using torsional wave elastography
This study proposed developing a procedure to reconstruct nonlinear fourth-order elastic properties of the cornea based on a mathematical model derived from the theory of Hamilton et al. and using the torsional wave elastography (TWE) technique. In order to validate its diagnostic capability of simulated pathological conditions, two different groups were studied, non-treated cornea samples (n=7), and ammonium hydroxide (\(NH_4OH\)) treated samples (n=7). All the samples were measured in-plane by a torsional wave device by increasing IOP from 5 to 25 mmHg with 5 mmHg steps. The results show a nonlinear variation of the shea...
Source: Australasian Physical and Engineering Sciences in Medicine - August 29, 2023 Category: Biomedical Engineering Source Type: research

Phantom study of layered sensor module for photon-counting BMD detector
In this study, we perform bone mineral density (BMD) calculation by designing a layered sensor module (LSM) that divides high- and low-energy spectra from a single shot of X-rays. Gamma-ray evaluation supports this mechanism; low-energy gamma rays are absorbed in the front detector, whereas high-energy gamma rays are absorbed in the rear detector. In this phantom study, LSM divides a single shot of X-ray into two spectra with different distributions of energy, thereby affording X-ray images with different properties, such as contrast and gray scale. The region of interest (ROI) is classified by the Prewitt operator to sort...
Source: Australasian Physical and Engineering Sciences in Medicine - August 28, 2023 Category: Biomedical Engineering Source Type: research

Shortening image registration time using a deep neural network for patient positional verification in radiotherapy
AbstractWe sought to accelerate 2D/3D image registration computation time using image synthesis with a deep neural network (DNN) to generate digitally reconstructed radiographic (DRR) images from X-ray flat panel detector (FPD) images. And we explored the feasibility of using our DNN in the patient setup verification application. Images of the prostate and of the head and neck (H&N) regions were acquired by two oblique X-ray fluoroscopic units and the treatment planning CT. DNN was designed to generate DRR images from the FPD image data. We evaluated the quality of the synthesized DRR images to compare the ground-truth...
Source: Australasian Physical and Engineering Sciences in Medicine - August 28, 2023 Category: Biomedical Engineering Source Type: research

Commissioning of a RayStation structure template for the iBEAM evo Couchtop
AbstractAccurate radiotherapy treatment planning requires attenuation through the treatment couch to be accounted for in dose calculation. This is commonly performed by using contouring tools to add a virtual structure in the shape of the treatment couch and assigning the preferred absorption properties. The RayStation treatment planning system (TPS) allows users to assign a material that comprises both an elemental structure and a physical density. The selection of such parameters should be made so that modelled attenuation through the couch closely matches measured data. When these measurements involve the use of plastic...
Source: Australasian Physical and Engineering Sciences in Medicine - August 24, 2023 Category: Biomedical Engineering Source Type: research

Development of hybrid feature learner model integrating FDOSM for golden subject identification in motor imagery
This study proposes a hybrid brain signal decoding model called Hybrid Adaboost Feature Learner ( HAFL), which combines feature extraction and classification using VGG-19, STFT, and Adaboost classifier. The model is validated using a pre-recorded MI-EEG dataset from the BCI competition at Graz University. The fuzzy decision-making framework is integrated with HAFL to allocate a golden subject fo r MI-BCI applications through the Golden Subject Decision Matrix (GSDM) and the Fuzzy Decision by Opinion Score Method (FDOSM). The effectiveness of the HAFL model in addressing inter-subject variability in EEG-based MI-BCI is eval...
Source: Australasian Physical and Engineering Sciences in Medicine - August 21, 2023 Category: Biomedical Engineering Source Type: research

Commissioning of Aktina SRS cones and dosimetric validation of the RayStation photon Monte Carlo dose calculation algorithm
AbstractClinical implementation of SRS cones demands particular experimental care and dosimetric considerations in order to deliver precise and safe radiotherapy to patients. The purpose of this work was to present the commissioning data of recent Aktina cones combined with a 6MV flattened beam produced by an Elekta VersaHD linear accelerator. Additionally, the modelling process, and an assessment of dosimetric accuracy of the RayStation Monte Carlo dose calculation algorithm for cone based SRS was performed. There are currently no studies presenting beam data for this equipment and none that outlines the modelling paramet...
Source: Australasian Physical and Engineering Sciences in Medicine - August 21, 2023 Category: Biomedical Engineering Source Type: research

Magnetic resonance-based imaging biopsy with signatures including topological Betti number features for prediction of primary brain metastatic sites
This study incorporated topology Betti number (BN) features into the prediction of primary sites of brain metastases and the construction of magnetic resonance-based imaging biopsy (MRB) models. The significant features of the MRB model were selected from those obtained from gray-scale and three-dimensional wavelet-filtered images, BN and inverted BN (iBN) maps, and clinical variables (age and gender). The primary sites were predicted as either lung cancer or other cancers using MRB models, which were built using seven machine learning methods with significant features chosen by three feature selection methods followed by ...
Source: Australasian Physical and Engineering Sciences in Medicine - August 21, 2023 Category: Biomedical Engineering Source Type: research

Radiomics based predictive modeling of rectal toxicity in prostate cancer patients undergoing radiotherapy: CT and MRI comparison
ConclusionsThis research showed that as radiomic signatures for predicting radiation-induced rectal toxicity, MR images outperform CT images. (Source: Australasian Physical and Engineering Sciences in Medicine)
Source: Australasian Physical and Engineering Sciences in Medicine - August 9, 2023 Category: Biomedical Engineering Source Type: research

Comparison of the accuracy of Monte Carlo and Ray Tracing dose calculation algorithms for multiple target brain treatments on CyberKnife
In conclusion, calculated dose disagreement in MBT depends on the number of GTVs per plan, number of GTVs within a certain separation distance and plan complexity. MC dose calculation is recommended for complex CyberKnife SRS of MBT. (Source: Australasian Physical and Engineering Sciences in Medicine)
Source: Australasian Physical and Engineering Sciences in Medicine - August 8, 2023 Category: Biomedical Engineering Source Type: research

Deep learning-based ultrasound transducer induced CT metal artifact reduction using generative adversarial networks for ultrasound-guided cardiac radioablation
AbstractIn US-guided cardiac radioablation, a possible workflow includes simultaneous US and planning CT acquisitions, which can result in US transducer-induced metal artifacts on the planning CT scans. To reduce the impact of these artifacts, a metal artifact reduction (MAR) algorithm has been developed based on a deep learning Generative Adversarial Network called Cycle-MAR, and compared with iMAR (Siemens), O-MAR (Philips) and MDT (ReVision Radiology), and CCS-MAR (Combined Clustered Scan-based MAR). Cycle-MAR was trained with a supervised learning scheme using sets of paired clinical CT scans with and without simulated...
Source: Australasian Physical and Engineering Sciences in Medicine - August 7, 2023 Category: Biomedical Engineering Source Type: research

Deep learning model fusion improves lung tumor segmentation accuracy across variable training-to-test dataset ratios
This study aimed to investigate the robustness of a deep learning (DL) fusion model for low training-to-test ratio (TTR) datasets in the segmentation of gross tumor volumes (GTVs) in three-dimensional planning computed tomography (CT) images for lung cancer stereotactic body radiotherapy (SBRT). A total of 192 patients with lung cancer (solid tumor, 118; part-solid tumor, 53; ground-glass opacity, 21) who underwent SBRT were included in this study. Regions of interest in the GTVs were cropped based on GTV centroids from planning CT images. Three DL models, 3D U-Net, V-Net, and dense V-Net, were trained to segment the GTV r...
Source: Australasian Physical and Engineering Sciences in Medicine - August 7, 2023 Category: Biomedical Engineering Source Type: research