Objective measurement of HINTS (Head Impulse, Nystagmus, Test of Skew) in peripheral vestibulopathy
To evaluate how often the positive sign of HINTS (Head-Impulse, Gaze Evoked Nystagmus, Test of Skew) appears in patients with acute peripheral vestibular lesion, HINTS findings were quantitatively measured and analyzed in patients with peripheral vestibulopathy accompanying spontaneous nystagmus. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - March 23, 2022 Category: ENT & OMF Authors: Dong-Han Lee, Erich Schneider, Sang-Yeon Lee, Ji-Soo Kim, Ja-Won Koo Tags: Original Article Source Type: research
Application of a strip design to monitor the viability of buried radial forearm free flap in East Asians: A case series study
The objectives of this study were to evaluate the reliability of a strip design as a monitoring flap in buried flap and to investigate whether strip design of radial forearm free flap (RFFF) could affect donor site morbidity in East Asian. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - March 20, 2022 Category: ENT & OMF Authors: Bo Hae Kim, Jeong-Yeon Ji, Min-Kyung Kim, Soon-Hyun Ahn, Eun-Jae Chung Tags: Original Article Source Type: research
Narrow band imaging accentuates differences in contrast between cartilage and perichondrium in the elevation of the muco-perichondrium flap during septoplasty and open septorhinoplasty
In the elevation of the muco-perichondrium flap during septoplasty and septorhinoplasty, it is important to elevate the subperichondrial layer. When performing subperichondrial elevation of the flap, the surgeon uses differences in color tone to distinguish the perichondrium from cartilage; however, it is relatively difficult to understand these differences and to share them with assistants. Furthermore, the perichondrium at the caudal end adheres tightly to the cartilage, making it difficult to detach accurately the subperichondrial layer. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - March 19, 2022 Category: ENT & OMF Authors: Keisuke Yamamoto, Tsuyoshi Okuni, Makoto Kurose, Takuya Kakuki, Masaya Nakano, Hiroshi Sakamoto, Kenichi Takano Tags: Original Article Source Type: research
Early postoperative complications and their measures after skull base reconstruction: A study from the standpoint of plastic and reconstructive surgeons
The objective of this study is to clarify the early postoperative survival-related complications after skull base reconstruction of which plastic surgeons should participate in treatment. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - March 18, 2022 Category: ENT & OMF Authors: Kentaro Tanaka, Nobuko Suesada, Tsutomu Homma, Takeaki Hidaka, Hiroki Mori, Mutsumi Okazaki, Takashi Sugawara, Takeshi Tsutsumi, Takahiro Asakage Tags: Original Article Source Type: research
Surgical strategy of locally advanced differentiated thyroid cancer
Approximately 20% of patients with differentiated thyroid cancer (DTC) have direct tumor extension with invasion of the surrounding tissues such as the larynx, trachea, esophagus, or recurrent laryngeal nerve. Recent progress of molecular-targeted therapy, such as the use of tyrosine kinase inhibitors, improves survival outcome in patients with advanced DTC. However, induction of tyrosine kinase inhibitors for locally-advanced DTC has presented novel fatal adverse events including fistula in patients with infiltration toward to the trachea, pharynx and esophagus, and fatal bleeding in patients with great vessel invasion. (...
Source: Auris, Nasus, Larynx - March 18, 2022 Category: ENT & OMF Authors: Keisuke Enomoto, Hidenori Inohara Source Type: research
Factors affecting the outcome of vestibular rehabilitation in patients with peripheral vestibular disorders
This study aimed to determine the factors associated with the outcome of physical-therapist-supervised vestibular rehabilitation in patients with peripheral vestibular disorders, with the impact of dizziness on quality of life as the main outcome. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - March 17, 2022 Category: ENT & OMF Authors: Hirofumi Ogihara, Tomohiko Kamo, Ryozo Tanaka, Masato Azami, Takumi Kato, Mayumi Endo, Reiko Tsunoda, Hiroaki Fushiki Tags: Original Article Source Type: research
Effects of salicylate derivatives on localization of p.H723R allele product of SLC26A4
Pendrin is a transmembrane protein encoded by the SLC26A4 gene that functions in maintaining ion concentrations in the endolymph of the inner ear, most likely by acting as a chloride/bicarbonate transporter. Variants in the SLC26A4 gene are responsible for sensorineural hearing loss. Although pendrin localizes to the plasma membrane, we previously identified that 8 missense allele products of SLC26A4 were retained in the intracellular region and lost their anion exchange function. We also found that 10 mM salicylate induced the translocation of 4 out of 8 allele products from the intracellular region to the plasma membrane...
Source: Auris, Nasus, Larynx - March 16, 2022 Category: ENT & OMF Authors: Michio Murakoshi, Yuhi Koike, Shin Koyama, Shinichi Usami, Kazusaku Kamiya, Katsuhisa Ikeda, Yoichi Haga, Kohei Tsumoto, Hiroyuki Nakamura, Noriyasu Hirasawa, Kenji Ishihara, Hiroshi Wada Tags: Original Article Source Type: research
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(Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - March 13, 2022 Category: ENT & OMF Source Type: research
Comparative study on adhesive otitis media and pars tensa cholesteatoma in children
Objective: Recurrent otitis media and persistent otitis media with effusion in early childhood may cause an atelectatic eardrum and adhesive otitis media, which sometimes progress to pars tensa cholesteatoma. When and how children with adhesive otitis media should be operated on remain controversial. Therefore, this study aimed to analyze the clinical characteristics of children with adhesive otitis media and pars tensa cholesteatoma, and to determine the risk factors of progression to cholesteatoma. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - March 2, 2022 Category: ENT & OMF Authors: Saeko Yoshida, Saori Seki, Tomonori Sugiyama, Saori Kikuchi, Naohiro Yoshida, Yukiko Iino Tags: Original Article Source Type: research
Clinical and electrophysiological findings of facial palsy in a case of hereditary gelsolin amyloidosis
We report a case of HGA presenting with bilateral facial palsy. A 70-year-old Japanese man presented with slowly progressive bilateral facial palsy and facial twitching, which had started in his 40s. His mother also had the same symptoms due to an unknown cause but rest of the family did not. He showed incomplete facial palsy with no frontal muscle movement and partial movement of the orbicularis oris and orbicularis oculi muscles. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - February 28, 2022 Category: ENT & OMF Authors: Kaoru Yamakawa, Hironobu Nishijima, Akatsuki Kubota, Hiroya Naruse, Shintaro Baba, Yoko Fujimaki, Kenji Kondo, Tatsushi Toda, Tatsuya Yamasoba Tags: Case Report Source Type: research
Relationship between serum gonadal hormone levels and synkinesis in postmenopausal women and man with idiopathic facial paralysis
To investigate whether serum gonadal hormone levels are correlated to the development of facial synkinesis following Bell's palsy in postmenopausal women and man. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - February 26, 2022 Category: ENT & OMF Authors: Wanchun Zhu, Zheng Chen, Yiman Shen, Haopeng Wang, Xiaomin Cai, Jin Zhu, Yinda Tang, Xuhui Wang, Shiting Li Tags: Original Article Source Type: research
Real-world 2-year long-term outcomes and prognostic factors in patients receiving nivolumab therapy for recurrent or metastatic squamous cell carcinoma of the head and neck
This study aimed to investigate the 2-year long-term outcomes and prognostic factors associated with the response to nivolumab. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - February 26, 2022 Category: ENT & OMF Authors: Shuya Otsuki, Ryusuke Hori, Shogo Shinohara, Tsuyoshi Kojima, Hisanobu Tamaki, Ryo Asato, Morimasa Kitamura, Kazuyuki Ichimaru, Yoshiharu Kitani, Yohei Kumabe, Keigo Honda, Takashi Tsujimura, Hiroyuki Harada, Koji Ushiro, Koichi Omori Tags: Original Article Source Type: research
Preoperative apnea-hypopnea index predicts increased postoperative intrathoracic pressure during sleep in patients who underwent endoscopic nasal surgery
Respiratory condition could worsen during sleep in patients with nasal packing following endoscopic nasal and sinus surgery (ESS) under general anesthesia. Recently, a noninvasive intrathoracic pressure estimation sensor was developed that uses photoplethysmographic pulse wave technology. The purpose of this study was to noninvasively evaluate the effect of bilateral nasal packing on respiration during sleep, using a photoplethysmographic pulse wave sensor in perioperative patients who underwent ESS under general anesthesia. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - February 17, 2022 Category: ENT & OMF Authors: Masaaki Suzuki, Kaori Kawai, Yuichi Kawai, Motomu Honjo, Taiji Furukawa Tags: Original Article Source Type: research
Sarcomatoid carcinoma in the sinonasal cavity: A retrospective case series from a single institution
This study aimed to summarize the clinical characteristics, treatment and prognosis of patients with sinonasal SC from a single tertiary medical center. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - February 16, 2022 Category: ENT & OMF Authors: Zhenzhen Zhu, Lei Wang, Weiqing Wang, Yang Zha, Xiaowei Wang, Jinbo Han, Wei Lv Tags: Original Article Source Type: research
Severe multiple simultaneous immune-related adverse events in a patient with head and neck cancer
Nivolumab, an immune checkpoint inhibitor (ICI) against the programmed death-1 pathway, has been used for the treatment of recurrent metastatic head and neck cancer. However, the management of immune-related adverse events (irAEs), a unique side effect of ICI therapy, can be problematic. Although severe irAEs have been reported to result from multi-ICI therapy, we report a case of multiple severe irAEs caused by single-agent nivolumab treatment. Nivolumab was administered to treat a case of hypopharyngeal cancer recurrence. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - February 15, 2022 Category: ENT & OMF Authors: Kazuma Aoki, Takao Hamamoto, Nobuyuki Chikuie, Takashi Kono, Takayuki Taruya, Takashi Ishino, Tsutomu Ueda, Sachio Takeno Tags: Case Report Source Type: research
