Withdrawal notice to: “Listening handicap in tinnitus patients by controlling extended high frequencies - Effort or fatigue?” [Auris Nasus Larynx 51 (2024) 198-205]
This article has been withdrawn: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal). (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - February 26, 2024 Category: ENT & OMF Authors: Eser Sendesen, Didem Turkyilmaz Source Type: research

From research to clinical practice: An analysis of 226 Hz-probe tone tympanometry to identify otitis media with effusion in children
(1) To calculate the sensitivity and specificity of tympanometry with a 226  Hz probe to identify middle ear condition in children; (2) To propose the intersection range of static compliance and tympanometric peak pressure values obtained in ears with and without middle ear effusion. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - December 21, 2023 Category: ENT & OMF Authors: K átia de Freitas Alvarenga, Alana Ribeiro de Melo, Marina Saes Rays, Alice Andrade Lopes Amorim, Lilian Cássia Bórnia Jacob, Eliene Silva Araújo Source Type: research

Vestibular compensation: Neural mechanisms and clinical implications for the treatment of vertigo
After unilateral peripheral vestibular lesions, the neural activity of neurons in the ipsi-lesional medial vestibular nucleus (ipsi-MVe) are markedly decreased, resulting in static and dynamic asymmetries of the vestibulo-ocular and vestibulo-spinal reflexes. Consequently, static vestibular symptoms such as spontaneous nystagmus and postural deviation and dynamic vestibular symptoms such as oscillopsia and swaying gait are induced. However, these behavioral asymmetries gradually recover after the lesion. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - December 18, 2023 Category: ENT & OMF Authors: Noriaki Takeda, Kazunori Matsuda, Junya Fukuda, Go Sato, Atsuhiko Uno, Tadashi Kitahara Source Type: research

Long term effects of cochlear implant surgery on vestibular system in pediatric population
The aim was to evaluate the vestibular system of children who had undergone cochlear implant surgery and to compare them with the healthy population by vestibulo-ocular reflex (VOR) gains in unilateral and bilateral implant users, with the implants both on and off. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - December 8, 2023 Category: ENT & OMF Authors: Ata Alperen Er şahan, Hasan Mervan Değer, Merve Durgut, Murat Öztürk, Fatih Mutlu Tags: Original Article Source Type: research

Efficacy, safety, and tissue penetration of solithromycin in Japanese patients with otorhinolaryngological infections
To assess the efficacy, safety, and tissue penetration of solithromycin for the treatment of otorhinolaryngological infections, we conducted three studies: a tissue penetration study with patients scheduled to undergo otorhinolaryngological tissue removal, an open-label study comprising patients with otitis media, pharyngitis, laryngitis, and tonsillitis, and a non-inferiority study compared with high-dose cefcapene-pivoxil (CFPN-PI). (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - December 7, 2023 Category: ENT & OMF Authors: Yuichi Kurono, Fumiyo Kudo, Akira Watanabe, Takahiro Yamatake, Satoshi Shimada, Kenji Suzuki Source Type: research

Sinonasal microbiome and inflammatory profiles in fungal ball and chronic rhinosinusitis
Fungal balls (FB) are the main form of non-invasive fungal rhinosinusitis found in immunocompetent hosts. Bacterial coinfection affects clinical symptoms. We investigated the sinonasal microbiome and inflammatory profiles in FB and chronic rhinosinusitis (CRS) patients. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - December 6, 2023 Category: ENT & OMF Authors: Daeyoung Roh, Ji-Hyeon Shin, Soo Whan Kim, Sung Won Kim, Byung-Guk Kim, Jin-Hee Cho, Yong-Jin Park, Do Hyun Kim Source Type: research

Peritonsillar abscess caused by Mycoplasma hominis and Fusobacterium necrophorum following oral sex
Mycoplasma hominis is a bacterium that colonizes the genital tract of some females and males, as well as their respiratory tracts. Although only two cases of deep neck infection have been reported, the associations between the onset and sexual intercourse have not been reported. A healthy 19-year-old female was diagnosed with a left peritonsillar abscess. The patient had sexual intercourse with a new partner, including oral sex, two days prior to symptom onset. It was not known whether the male partner had urethritis symptoms. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - December 2, 2023 Category: ENT & OMF Authors: Hiroshi Morioka, Hideyuki Kaida, Mitsuru Nishio, Kenji Suga Tags: Case Report Source Type: research

Understanding hereditary hemorrhagic telangiectasia: From genetic anomalies to systemic manifestations, quality of life, and epistaxis management —Exploring the otolaryngologist's integral role
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler –Rendu–Weber syndrome, is a rare autosomal dominant disorder characterized by vascular malformations. This comprehensive review aimed to provide an overview and summarize various aspects of HHT, including the genetic abnormalities, complications associated with visceral arteriovenous malformatio ns (AVMs), prognosis of HHT, quality of life (QOL), and treatment of epistaxis. In addition, this review highlights the challenges in diagnosing HHT and emphasizes the critical role of otolaryngologists in the early detection of HHT. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 25, 2023 Category: ENT & OMF Authors: Masaki Hayama, Yohei Maeda, Sho Obata, Takeshi Tsuda, Kazuya Takeda, Takeo Nishida, Hidenori Inohara Source Type: research

Lipids and sudden sensorineural hearing loss: A bidirectional two-sample Mendelian randomization analysis
While numerous observational studies have indicated an association between lipids and Sudden Sensorineural Hearing Loss (SSNHL), it remains uncertain whether dyslipidemia serves as a causal risk factor for SSNHL. Our objective is to elucidate the potential causal relationship between lipid levels and SSNHL through Mendelian randomization analysis. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 22, 2023 Category: ENT & OMF Authors: Kunlin Pu, Li Li, Yan Qiu, Hongmei Song Source Type: research

Useful combination of Gehanno method, polyglycolic acid sheet and fibrin glue for prevention of postoperative dysfunction after soft palate resection with TORS
We report the case of a patient with oropharyngeal cancer in which half of the soft palate was resected, and good function was maintained using the Gehanno method, polyglycolic acid (PGA) sheet and fibrin glue. The patient was a woman in her 50  s with oropharyngeal squamous cell carcinoma (p16-positive, T2N1M0 stage I). (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 18, 2023 Category: ENT & OMF Authors: Kiyoaki Tsukahara, Kenji Hanyu, Akira Shimizu Source Type: research

Effectiveness of FEES with artificial intelligence-assisted computer-aided diagnosis
FEES is a standard procedure for diagnosing dysphagia. However, appropriate evaluation of FEES findings is difficult for inexperienced evaluators. Recent progress in deep learning has highlighted the use of artificial intelligence-assisted computer-aided diagnosis (AI-assisted CAD) in medical applications. We investigated the detection accuracy of FEES findings evaluated by inexperienced evaluators with and without the use of CAD. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 16, 2023 Category: ENT & OMF Authors: Mitsuyoshi Imaizumi, Weihao Weng, Xin Zhu, Shigeyuki Murono Source Type: research

New insights into chronic rhinosinusitis associated with IgG4-related disease
IgG4-related disease (IgG4-RD) is a chronic inflammatory disorder characterized by elevated IgG4 serum levels, abundant IgG4-positive plasmacyte infiltration, and fibrosis of various organs, including the head and neck. We aimed to provide an overall review of IgG4-RD in the sinonasal region and propose a novel entity and criteria of chronic rhinosinusitis (CRS) associated with IgG4-RD as “IgG4-CRS,” a distinct manifestation of IgG4-RD in the sinonasal region. Sinonasal involvement has been increasingly recognized; however, this region is not included in the classic IgG4-RD-affected organs. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 14, 2023 Category: ENT & OMF Authors: Kenichi Takano, Ryuta Kamekura, Tsuyoshi Okuni, Keisuke Yamamoto Source Type: research

Targeted next-generation sequencing of Japanese patients with sinonasal mucosal melanomas identifies frequent NRAS and CTNNB1 mutations
Mucosal melanoma is a rare malignancy; however, the reported incidence rate of mucosal melanoma is higher in Asians than in Caucasians. Sinonasal mucosal melanoma (SNMM) is an aggressive malignancy with a poor prognosis due to distant metastasis. Systemic therapy with BRAF inhibitor and MEK inhibitor is one of the standards of care for cutaneous melanoma patients with BRAF V600 mutations. However, no molecular targeted therapy for patients with mucosal melanoma has been established. Relatively few studies have described the genetic mutations associated with mucosal melanoma because of its low frequency. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 10, 2023 Category: ENT & OMF Authors: Nayuta Tsushima, Satoshi Kano, Kanako C. Hatanaka, Takayoshi Suzuki, Seijiro Hamada, Hiroshi Idogawa, Yuji Nakamaru, Masanobu Suzuki, Yutaka Hatanaka, Akihiro Homma Source Type: research

Central node dissection from the perspective of lateral neck node metastasis in papillary thyroid carcinoma
Controversy exists on how to handle central lymph nodes in papillary thyroid carcinoma, particularly regarding indications for prophylactic central neck dissection (CND). Central node metastases are more difficult to diagnose preoperatively than lateral node metastases. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - November 7, 2023 Category: ENT & OMF Authors: Masataka Taniuchi, Ryo Kawata, Tetsuya Terada, Masaaki Higashino, Teruhito Aihara, Tsuyoshi Jinnin Source Type: research

Safety and efficacy of high tracheostomy with inferior retraction of the thyroid isthmus
In typical surgical tracheostomy, the thyroid isthmus is divided or retracted superiorly and preserved. However, at our institution, the thyroid isthmus is retracted inferiorly and preserved. Thereafter, a tracheal incision is made above the thyroid isthmus. This method, hereinafter defined as high tracheostomy, has the advantage of facilitating immediate access to the trachea in a superficial position; moreover, it can be quickly replaced with cricothyrotomy in emergency situations. However, tracheotomies placed too high can potentially damage the cricoid cartilage, thereby causing subglottic granulation and tracheal sten...
Source: Auris, Nasus, Larynx - November 3, 2023 Category: ENT & OMF Authors: Daisuke Iokura, Yusuke Okanoue, Shuya Otsuki, Kengo Oe, Kuniaki Takata, Akihito Tarui, Tsuyoshi Kojima Source Type: research