Freeze-Dried Platelet-Rich Plasma Induces Osteoblast Proliferation via Platelet-Derived Growth Factor Receptor-Mediated Signal Transduction.
Conclusions: We demonstrated the pharmacological activity of PDGF in FD-PRP in vitro after 4 weeks of storage. PMID: 31575111 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 4, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Efficacy of Pulsed Low-Frequency Magnetic Field Therapy on Patients with Chronic Low Back Pain: A Randomized Double-Blind Placebo-Controlled Trial.
Authors: Alzayed KA, Alsaadi SM Abstract Study Design: A randomized double-blind placebo-controlled trial. Purpose: To investigate the efficacy of pulsed electromagnetic field (PEMF) therapy combined with therapeutic exercises in the treatment of chronic low back pain (CLBP). Overview of Literature: Low back pain (LBP) is the most common musculoskeletal pain disorder. Most available interventions for CLBP have modestly beneficial outcomes. Despite the potential effect of PEMF therapy on LBP, there have been few studies regarding its effectiveness. Methods: Forty-two patients (22 males, 20 females), were...
Source: Asian Spine Journal - October 4, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Role of Virtual Reality in Balance Training in Patients with Spinal Cord Injury: A Prospective Comparative Pre-Post Study.
Conclusions: VR is an adjunctive therapy for balance rehabilitation in patients with SCI. PMID: 31575113 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 4, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

The Effect of Bracing on Spinopelvic Rotation and Psychosocial Parameters in Adolescents with Idiopathic Scoliosis.
Conclusions: The Cobb angle and AVR are crucial measurements that help evaluate the treatment efficacy in AIS with small curves who undergo brace treatment. HRQOL and pelvic axial rotation are not influenced by the brace treatment. PMID: 31434463 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 24, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Objective Monitoring of Brace Wearing Time in Adolescents with Scheuermann's Kyphosis.
This study aimed to evaluate the potential differences between the objective and subjective bracing compliances of adolescents with Scheuermann's kyphosis. Overview of Literature: Bracing is a well-documented intervention for managing adolescents with progressive thoracic Scheuermann's kyphosis, and the brace should be worn 23 hours every day. Most research studies that have investigated the efficacy of bracing have assumed that the patients wore the braces as advised or that the bracing time was measured subjectively. This may be one of the reasons for the conflicting reports regarding the efficacy of bracing. Met...
Source: Asian Spine Journal - August 24, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Antidepressants in Spine Surgery: A Systematic Review to Determine Benefits and Risks.
Authors: Bayoumi AB, Ikizgul O, Karaali CN, Bozkurt S, Konya D, Toktas ZO Abstract Antidepressant drugs can be advantageous in treating psychiatric and non-psychiatric illnesses, including spinal disorders. However, spine surgeons remain unfamiliar with the advantages and disadvantages of the use of antidepressant drugs as a part of the medical management of diseases of the spine. Our review article describes a systematic method using the PubMed/Medline database with a specific set of keywords to identify such benefits and drawbacks based on 17 original relevant articles published between January 2000 and February ...
Source: Asian Spine Journal - August 21, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

A Retrospective Review of Radiographic and Clinical Findings from the M6 Cervical Prosthesis.
Conclusions: The M6 new-generation cervical disk prosthesis had few complications. No heterotopic ossiication was observed in any patient, and lexion-extension ROM was maintained in all the patients, indicating the M6 prosthesis as a promising alternative. PMID: 31422645 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 21, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Periapical Wires Result in Less Curve Correction Than Pedicle Screw Constructs in Idiopathic Scoliosis.
The objective of this study was to compare percent correction between apical and periapical pedicle screw (PS) and sublaminar wire constructs for Cobb correction and coronal balance correction. Overview of Literature: The current gold standard for deformity correction in adolescent idiopathic scoliosis (AIS) are PS constructs. Sublaminar wires provide an alternative means of fixation when PS fixation cannot be safely performed. Two previous studies have compared percent curve correction between sublaminar wires and PSs, with conflicting conclusions. Methods: The study was a retrospective review of Lenke type 1 curv...
Source: Asian Spine Journal - August 21, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Insertion Angle of Pedicle Screws in the Subaxial Cervical Spine: The Analysis of Computed Tomography-Navigated Insertion of Pedicle Screws.
Conclusions: The present results show that the insertion angle of the pedicle screws in the subaxial cervical spine was smaller than the actual pedicle transverse angle, as per the literature. One reason for this discrepancy could be that the navigation systems allow the insertion of cervical pedicle screws with a lower convergence. PMID: 31352719 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Patient Satisfaction in Spine Surgery: A Systematic Review of the Literature.
Authors: Menendez JY, Omar NB, Chagoya G, Tabibian BE, Elsayed GA, Walters BC, Guthrie BL, Hadley MN Abstract Patient satisfaction reflects the patients' perception of the outcome of care and is being considered for use in future reimbursement schemes. No consensus exists regarding the best instrument to measure patient satisfaction in the field of spine surgery. This systematic review aimed to determine how patient satisfaction for spine surgery has been measured previously and whether a disease-specific, comprehensive instrument to measure patient satisfaction has been established; we also aimed to define the dim...
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Comparative Evaluation of Pregabalin and Clonidine as Preemptive Analgesics for the Attenuation of Postoperative Pain Following Th oracolumbar Spine Surgery.
Authors: Bala R, Kaur J, Sharma J, Singh R, Singh R Abstract Study Design: Prospective, randomized, double blind, placebo-controlled study. Purpose: To compare clonidine and pregabalin with placebo for the attenuation of postoperative pain after thoracolumbar spinal surgery and instrumentation. Overview of Literature: Spine surgery is associated with moderate to severe postoperative pain that needs to be controlled to improve patient's outcome. Alpha 2 agonists (e.g., clonidine) and gabapentenoids (e.g., pregabalin) are successfully used as part of a multimodal analgesic regimen. Methods: Total 75 patie...
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Analysis of the Functional and Radiological Outcomes of Lumbar Decompression without Fusion in Patients with Degenerative Lumbar Scoliosis.
This study aimed to analyze the functional and radiological outcomes of lumbar decompression in patients with degenerative lumbar scoliosis (DLS). Overview of the Literature: Patients with DLS have symptoms related to lumbar canal stenosis (LCS) and those due to compensated spinal imbalance. Whether the deformity is the cause of pain or is an adaptive change for the ongoing LCS remains debatable. The extensive surgery for deformity correction along with spinal fusion is reported to have high perioperative morbidity and complication rate. Methods: This retrospective analysis involved 51 patients who underwent lumbar...
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Role of Additional Coronal Magnetic Resonance Imaging in Decompression and Reconstruction with or without Segment Salvage in Thoracic Spine Tuberculosis.
Conclusions: For segment salvage, having a clear three-dimensional idea about the viable remnant bone is important. Viable salvaged segment reduces the morbidity of the procedure, length of the construct, and unnecessary debridement without compromising on the neural recovery and fusion rate. Hence, additional cone down coronal cuts must be required when MRI is suggestive for spinal TB because it will help in the decision making. PMID: 31352723 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Esophageal Perforation after Anterior Cervical Spine Surgery.
Conclusions: The main cause of intraoperative esophageal perforation was esophageal adhesions because of infectious spondylitis. However, perioperative and delayed esophageal perforations were caused by chronic irritation because of metal failure. Anterior plate and screw removal was necessary, and posterior instrumentation and fusion may be considered, depending on the fusion status. PMID: 31352724 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Treatment of Adult Spinal Deformity with Sagittal Imbalance Using Oblique Lumbar Interbody Fusion: Can We Predict How Much Lordosis Correction Is Possible?
Conclusions: Although OLIF offers many advantages, it alone plays a limited role in ASD treatment. Lordosis correction using OLIF as well as lordosis determined in the FELV was possible. Hence, our results suggest that FELV can help predict the lordosis correction angle preoperatively and thus aid the selection of the appropriate technique in the second staged operation. PMID: 31352725 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Comparison of Segmental Mobility in Lumbar Extension Radiographs between a New Technique ("Fulcrum Bending Position") and Conventional Standing Position in Spondylolisthesis Patients.
Comparison of Segmental Mobility in Lumbar Extension Radiographs between a New Technique ("Fulcrum Bending Position") and Conventional Standing Position in Spondylolisthesis Patients. Asian Spine J. 2019 Jul 30;: Authors: Pruttikul P, Maneesrisajja T, Urusopon P, Pluemvitayaporn T, Piyaskulkaew C, Kunakornsawat S, Kittithamvongs P Abstract Study Design: Cross-sectional study. Purpose: This was carried out to evaluate the benefit of a 'fulcrum bending position' compared with the standing position for evaluation of sagittal translation and sagittal rotation in symptomatic patients with spon...
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

The Role of Calcium Pyrophosphate Dihydrate Deposition in the Postoperative Outcome of Lumbar Spinal Stenosis Patients.
Conclusions: Surgical intervention resulted in good clinical outcomes in SCPPD patients. As per our findings, total removal of CPPinvolved tissue is unnecessary. As such, surgery should be performed as indicated according to clinical presentation without considering the presence of CPPD. PMID: 31352727 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Extended Posterior Decompression and Instrumented Fusion for Spinal Tuberculosis.
Authors: Kunakornsawat S, Philawuth N, Piyaskulkaew C, Pruttikul P, Pluemvitayaporn T, Kittithamvongs P Abstract Study Design: Retrospective cohort. Purpose: To evaluate clinical outcomes, including pain and neurologic status, and to evaluate radiographic outcomes of patients treated with extended posterior decompression, posterior fixation, and fusion in different vertebral segments. Overview of Literature: The standard surgical treatment of spinal tuberculosis is radical debridement via anterior approach. However, this approach may lead to several serious complications. Meanwhile, extended posterior appro...
Source: Asian Spine Journal - July 30, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

The Optimal Screw Length of Lumbar Pedicle Screws during Minimally Invasive Surgery Fixation: A Computed Tomography-Guided Evaluation of 771 Screws.
Conclusions: During MIS pedicle screw fixation, this study recommends that pedicle screws should not exceed 85% of the vertebral body length on the lateral view for L1, 80% for L2-L4, and 75% for L5; this will minimize the risk of anterior cortical breach yet maximize pedicle screw purchase for fixation stability. PMID: 31309769 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 18, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Anatomic Considerations of Anterior Transarticular Screw Fixation for Atlantoaxial Instability.
Conclusions: If the screw was inserted without lateral angulation, the spinal canal or cord could be violated. If a longer screw was inserted with greater posterior angulation, the vertebral artery at the posterior or posterolateral aspect of the C1 superior facet could be violated. Thus, 26° and 30° of lateral and posterior angulations, respectively, are the maximum angles permissible to avoid injury of the vertebral artery and violations of the spinal canal or atlanto-occipital joint. PMID: 31309770 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 18, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Learning Curve for Robot-Assisted Percutaneous Pedicle Screw Placement in Thoracolumbar Surgery.
Conclusions: We found that robot-assisted screw placement had high accuracy, low placement time, low fluoroscopy time, and a low complication rate. However, there were no significant differences in these parameters at the initial experience and the practiced, experience placement (after approximately 1 year), indicating that robot-assisted pedicle screw placement has a very short (almost no) learning curve. PMID: 31281174 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 10, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Changes in Sagittal Alignment Following Short-Level Lumbar Interbody Fusion: Comparison between Posterior and Lateral Lumbar Interbody Fusions.
Authors: Nakashima H, Kanemura T, Satake K, Ishikawa Y, Ouchida J, Segi N, Yamaguchi H, Imagama S Abstract Study Design: Retrospective case-control study. Purpose: We aimed to compare radiologic outcomes between posterior (PLIF) and lateral lumbar interbody fusion (LLIF) in short-level spinal fusion surgeries. Overview of Literature: Although LLIF enables surgeons to insert large lordotic cages, it is unknown whether LLIF more effectively corrects local and global sagittal alignments compared with PLIF in short-level spinal fusion surgeries. Methods: Radiographic data acquired from patients with lumbar ...
Source: Asian Spine Journal - July 10, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Kyphosis Progression after Balloon Kyphoplasty Compared with Conservative Treatment.
This study retrospectively analyzed 129 patients treated conservatively and 95 treated with BKP in our institution. The rate of new adjacent fracture occurrence was determined using Kaplan-Meier analysis. We examined the progression of local kyphosis in patients who underwent lateral X-ray after 1 year. Local kyphosis was measured as an angle between higher end plate of the vertebra above and lower end plate of the vertebra below the fractured vertebra. The comparison included 45 patients treated conservatively and 58 treated with BKP. Results: The incidence of new adjacent fracture at 1 year was 7.3% in the conservati...
Source: Asian Spine Journal - July 10, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Hypertension Is Related to Positive Global Sagittal Alignment: A Cross-Sectional Cohort Study.
Conclusions: This study showed that hypertension was associated with forward-shifted global sagittal alignment. PMID: 31281177 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - July 10, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Responsiveness of Commonly Used Patient- Reported Outcome Instruments in Lumbar Microdiscectomy.
Conclusions: ODI, RMDQ, SF-12 PCS, and SF-12 MCS demonstrated adequate responsiveness in a homogenous cohort of patients who underwent lumbar micro-discectomy. ODI and RMDQ are equally responsive and, thus, are interchangeable instruments for region specific outcomes. Both the SF-12 PCS and SF-12 MCS can assess the quality of life following lumbar micro-discectomy. PMID: 31154699 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Functional Outcome after Endoscopic Lumbar Discectomy by Destandau's Technique: A Prospective Study of 614 Patients.
Conclusions: ELD provides a safe, effective, and minimal access corridor for lumbar discectomy. The technique also allows early postoperative mobilization and faster return-to-work. PMID: 31154700 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Thoracic Posture and Mobility in Mechanical Neck Pain Population: A Review of the Literature.
Authors: Joshi S, Balthillaya G, Neelapala YVR Abstract Neck pain is a common condition with several proposed biomechanical contributing factors. Thoracic spine dysfunction is hypothesized as one of the predisposing factors, which necessitates the need to explore the contribution of thoracic posture and mobility toward neck pain. Accordingly, the present work aimed to review the existing literature investigating the presence of thoracic spine dysfunction in individuals with neck pain. A literature search was conducted in the three electronic databases of PubMed, CINAHL, and Web of Science. Studies published between...
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Effect of Indirect Neural Decompression with Oblique Lateral Interbody Fusion Was Influenced by Preoperative Lumbar Lordosis in Adult Spinal Deformity Surgery.
Authors: Beng TB, Kotani Y, Sia U, Gonchar I Abstract Study Design: Retrospective clinical study on the indirect decompressive effect of oblique lateral interbody fusion (OLIF) for adult spinal deformity. Purpose: To evaluate the effect of interbody distraction by OLIF for the treatment of adult spinal deformity. Overview of Literature: Adult spinal deformity with symptomatic stenosis has been addressed conventionally using a direct posterior decompression approach with fusion. However, stenotic symptoms can also be alleviated indirectly through restoration of intervertebral and foraminal heights and correc...
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Surgical Results of Patients with Myelopathy due to Ossification of the Ligamentum Flavum with Ossification of the Posterior Longitudinal Ligament or a Vertebral Fracture at the Same Level of the Thoracic Spine: A Retrospective Comparative Study.
Conclusions: Thoracic myelopathy due to OLF+VF occurs primarily in older females, who also exhibit worse preoperative and postoperative neurological status, and worse walking ability, than patients with thoracic myelopathy due to OLF or OLF+OPLL. PMID: 31154703 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Factors Affecting Postoperative Sagittal Alignment after Lateral Lumbar Interbody Fusion in Adult Spinal Deformity: Posterior Osteotomy, Anterior Longitudinal Ligament Rupture, and Endplate Injury.
Authors: Nakashima H, Kanemura T, Satake K, Ishikawa Y, Ouchida J, Segi N, Yamaguchi H, Imagama S Abstract Study Design: Prospective cohort study. Purpose: To identify factors that affect sagittal alignment correction in lateral lumbar interbody fusion (LIF) surgery for adult spinal deformity (ASD) and to investigate the degree of correction in each condition. Overview of Literature: LIF is a useful procedure for ASD, but the degree of correction can be affected by posterior osteotomy, intraoperative endplate injury, or anterior longitudinal ligament (ALL) rupture. Methods: Radiographical data for 30 pa...
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Feasibility and Safety of Outpatient Lumbar Microscopic Discectomy in a Developing Country.
Conclusions: Outpatient MLD can be safely performed with success, even in the setting of a developing country, if the prerequisites of appropriate patient selection, arduous adherence to outpatient surgery protocol, competent surgical/anesthetic team, and infrastructure needed for conduction of microsurgery are met. PMID: 31154705 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Pullout Strength Predictor: A Machine Learning Approach.
Conclusions: This model can be used clinically for understanding the failure of pedicle screw pullout and pre-surgical planning for spine surgeon. PMID: 31154706 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Frailty Syndrome and the Use of Frailty Indices as a Preoperative Risk Stratification Tool in Spine Surgery: A Review.
Authors: Simcox T, Antoku D, Jain N, Acosta F, Hah R Abstract This comprehensive narrative literature review aims to extract studies related to frailty indices and their use in elective spine procedures, as limited studies regarding frailty exist in the spine literature. Most studies are retrospective analyses of prospectively collected databases. Evidence suggests a positive correlation between frailty level and mortality rate, postoperative complication rate, length of stay, and the possibility of discharge to a skilled nursing facility; these correlations have been illustrated across various spine procedures. Th...
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Precautions for Combined Anterior and Posterior Long-Level Fusion for Adult Spinal Deformity: Perioperative Surgical Complications Related to the Anterior Procedure (Oblique Lumbar Interbody Fusion).
Conclusions: OLIF yielded more than expected endplate injuries from treatment modalities for ASD along with sagittal imbalance. Therefore, surgeons should be cautious about endplate injury during OLIF procedures. It is difficult to accomplish lordosis correction via OLIF alone; therefore, surgeons should not attempt this impractical correction goal and insert an immoderate cage. PMID: 31154755 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - June 5, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Ten-Year Results of Reconstruction for Rheumatoid Cervical Spine Lesions and Occurrence Factor of Subaxial Subluxation.
Conclusions: Patients with rheumatoid cervical lesions who undergo atlantoaxial or occipitocervical fixation using C1-C2 transarticular or pedicle screws carry a risk of SAS for up to 10 years postoperatively, which may require reoperation. PMID: 31079426 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Characteristics of Low Back Pain due to Superior Cluneal Nerve Entrapment Neuropathy.
Authors: Miki K, Kim K, Isu T, Matsumoto J, Kokubo R, Isobe M, Inoue T Abstract Study Design: Retrospective analysis. Purpose: The present study aimed to investigate the features of low back pain (LBP) due to superior cluneal nerve (SCN) entrapment neuropathy (SCN-EN) using the Roland Morris Disability Questionnaire (RMDQ), and to analyze the differences between LBP due to SCN-EN and lumbar spinal canal stenosis (LSS). Overview of Literature: The SCN is derived from the cutaneous branches of the dorsal rami of T11-L5 and passes through the thoracolumbar fascia. LBP due to SCN-EN is exacerbated by various ty...
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Investigation of Comorbidity, Trauma History, and Osteoporotic Fractures in the Postmenopausal Population: A Nationwide, Observational, and Cross-Sectional Study of Korean Orthopedic Outpatient Clinics.
Conclusions: Postmenopausal women are liable to have osteoporotic fractures due to the high prevalence of osteoporosis, a history of falling, and the comorbidity with diseases that restrict ambulation. A better understanding of postmenopausal women in the orthopedic outpatient settings is important to the management of osteoporotic fractures. PMID: 31079428 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Autogenic Rib Graft for Atlantoaxial and Occipitocervical Fixation in Pediatric Patients.
Conclusions: Autogenic rib grafts have advantages of potential bone regeneration, high fusion rate, and low donor-site morbidity. In addition, a screw-rod construct provides better bony fusion in pediatric patients with OCF and atlantoaxial fixation. PMID: 31079429 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

C2 Fractures in the Elderly: Single-Center Evaluation of Risk Factors for Mortality.
Conclusions: The CCI was a useful tool for predicting mortality at 1 year in the patient cohort. Other variables, including common laboratory markers, can also be used for risk stratification, to initiate timely multidisciplinary management, and prognostic counseling for patients and family members. PMID: 31079430 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Posterior Dural Shifts Following Spinous Process-Splitting Multi-Level Intervertebral Lumbar Laminectomies.
We examined 37 patients who underwent spinous process-splitting laminectomies in at least two intervertebral levels, including at the L5/S level. We defined the distance between the vertebral bodies and the anterior edge of the dural sac in the magnetic resonance images at the L5 vertebral level as the anterior dural space (ADS) and detected the difference (d-ADS) between preoperative ADS (pre-ADS) and postoperative ADS (post-ADS). We assessed the relationship between ADS or d-ADS, and preoperative parameters, including age, sex, lumbar lordosis, focal lordosis (FL), and number of decompression levels. Results: Post-AD...
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Comparison of Transforming Growth Factor-Beta1 and Lovastatin on Differentiating Mesenchymal Stem Cells toward Nucleus Pulposus-like Phenotype: An In Vitro Cell Culture Study.
Conclusions: This study demonstrates a promising role of lovastatin in inducing human MSCs into NP-like cells. However, further optimization of cell density before lovastatin treatment, treatment duration, and combination with TGF-β1 are warranted to attain better stimulatory effects. PMID: 31079432 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Hooks at the Upper Instrumented Vertebra Can Adjust Postoperative Shoulder Balance in Patients with Adolescent Idiopathic Scoliosis: 5 Years or More of Follow-up.
This study aims to investigate postoperative shoulder imbalance (PSI) ≥5 years postoperatively in patients who underwent posterior spinal fusion using hooks at the upper instrumented vertebra (UIV) for Lenke type 1 adolescent idiopathic scoliosis (AIS). Overview of Literature: Studies have reported PSI due to excessive correction of the main thoracic curve. Methods: We examined 56 patients with AIS who underwent a posterior spinal fusion with hooks at the UIV from 2004 to 2010. Of these, we enrolled 14 patients who underwent surgery, at least, 5 years ago. X-rays and Scoliosis Research Society-22 (SRS-22) questi...
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Mid-length Pedicle Screws in Posterior Instrumentation of Scoliosis.
Authors: Balikci T, Kıyak G, Heydar AM, Bawaneh MK, Bezer M Abstract Study Design: Prospective analysis of collected data. Purpose: We determine the need for the use of mid-length pedicle screws (screws with 2.5-mm long increments) during posterior spinal instrumentation. Overview of Literature: Many biomechanical studies have been performed showing that increasing the pedicle screw insertion depth provides an improved resistance to pullout, cyclic loading, and derotational forces, but no intermediate length screws were used. Methods: We prospectively evaluated 120 patients who received posterior segme...
Source: Asian Spine Journal - May 14, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Effects of Weekly Teriparatide Administration for Vertebral Stability and Bony Union in Patients with Acute Osteoporotic Vertebral Fractures.
Conclusions: Once-weekly TPTD administration may facilitate early bony union after acute OVF accompanied by severe osteoporosis. PMID: 31000686 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - April 20, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Evaluation of Challenges in Diagnosis of Spontaneous Subacute Pyogenic Spondylodiscitis in Immunocompetent Patients: Experiences from a Tertiary Care Center.
Conclusions: Diagnosing subacute spondylodiscitis in a patient presenting with subacute low backache poses a diagnostic challenge. Clinical and radiologic picture are deceiving, and bacteriologic results often are negative, further complicating the picture. A detailed medical history along with clinical, radiologic, and biochemical parameters prevents missing the diagnosis. Serial serum Creactive protein and alkaline phosphatases were more reliable blood parameters in cases of subacute presentation. PMID: 30966724 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - April 12, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Quantitative Predictive Imaging Biomarkers of Lumbar Intervertebral Disc Degeneration.
We examined 59 healthy controls and 59 patients with back pain by MRI using T2 relaxometry and diffusion tensor imaging (DTI). Each group was divided into three age subgroups: A (50 years, n=21). We obtained FA values for AF and NP and T2 values for NP for each intervertebral disc. Furthermore, we calculated the FA (AF/NP) ratios. Results: We categorized 590 intervertebral discs from 118 participants, 566 of which were analyzed with T2 relaxometry and DTI. The T2 values were as follows: subgroup A, 55.8±4.4 ms; B, 48.5±6.9 ms; C, 45.8±8.7 ms (p120 ms, 90-100 ms, and 70 ms, respectively (p
Source: Asian Spine Journal - April 12, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Investigation of the Neuropathic Pain Caused by Syringomyelia Associated with Chiari I Malformation.
Conclusions: This study showed a correlation between the morphological features of the syringes and the occurrence of neuropathic pain in patients with syringomyelia associated with Chiari I malformation. PMID: 30966726 [PubMed - as supplied by publisher] (Source: Asian Spine Journal)
Source: Asian Spine Journal - April 12, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Biportal Endoscopic Spinal Surgery for Lumbar Spinal Stenosis.
Authors: Kim JE, Choi DJ, Park EJJ, Lee HJ, Hwang JH, Kim MC, Oh JS Abstract Biportal endoscopic spinal surgery (BESS) is a minimally invasive spinal surgery, which is basically similar to microscopic spinal surgery in terms of the use of floating technique and technically similar to conventional percutaneous endoscopic spinal surgery in terms of the use of endoscopic or arthroscopic instruments. Using two independent portals (viewing and working) and maintaining a certain distance from the bony and neural structures allow closer access to the target lesion through a panoramic view by free handling of the scope and...
Source: Asian Spine Journal - April 10, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Obtaining Pentosidine Levels as an Adjunct to Determine a Patient's Candidacy for Vertebral Stabilization for a Vertebral Compression Fracture.
Authors: Viswanath O, Orhurhu V, Urits I Abstract PMID: 30959589 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - April 10, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Response to: Obtaining Pentosidine Levels as an Adjunct to Determine a Patient's Candidacy for Vertebral Stabilization for a Vertebral Compression Fracture.
Authors: Choi YS Abstract PMID: 30959590 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - April 10, 2019 Category: Orthopaedics Tags: Asian Spine J Source Type: research