Non-Caseating Granulomatous Infective Spondylitis: Melioidotic Spondylitis.
CONCLUSIONS: Melioidosis presents with a clinical spectrum similar to that of tuberculosis. A diagnosis of melioidotic spondylitis should be considered, particularly in patients with diabetes with neutrophilic leukocytosis and clinical-radiological features suggestive of infective spondylodiscitis. Bacteriological culture and histopathology helps in differentiating the two conditions. Health education for healthcare professionals is important for correctly diagnosing this disease. PMID: 27994782 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Closed Drainage versus Non-Drainage for Single-Level Lumbar Disc Surgery: Relationship between Epidural Hematoma and Fibrosis.
CONCLUSIONS: In patients operated on by unilateral, single-level lumbar disc surgery, the use of suction CSD into the operation site results in lower levels of EH and EF radiologically, thereby providing a better clinical outcome. PMID: 27994783 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Tumor Occupation in the Spinal Canal and Clinical Symptoms of Cauda Equina Schwannoma: An Analysis of 22 Cases.
CONCLUSIONS: PTO>20% in axial slices and>40% in sagittal slices can be an indication of symptomatic cauda equina schwannoma. PMID: 27994784 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Baastrup's Disease Is Associated with Recurrent of Sciatica after Posterior Lumbar Spinal Decompressions Utilizing Floating Spinous Process Procedures.
Authors: Koda M, Mannoji C, Murakami M, Kinoshita T, Hirayama J, Miyashita T, Eguchi Y, Yamazaki M, Suzuki T, Aramomi M, Ota M, Maki S, Takahashi K, Furuya T Abstract STUDY DESIGN: Retrospective case-control study. PURPOSE: To determine whether kissing spine is a risk factor for recurrence of sciatica after lumbar posterior decompression using a spinous process floating approach. OVERVIEW OF LITERATURE: Kissing spine is defined by apposition and sclerotic change of the facing spinous processes as shown in X-ray images, and is often accompanied by marked disc degeneration and decrement of disc height. If kis...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Bone Morphogenic Protein Is a Viable Adjunct for Fusion in Minimally Invasive Transforaminal Lumbar Interbody Fusion.
Authors: Siddiqui MM, Sta Ana AR, Yeo W, Yue WM Abstract STUDY DESIGN: Comparison of prospectively collected data of patients undergoing minimally invasive surgery transforaminal lumbar interbody fusion (MIS-TLIF) with and without recombinant human bone morphogenic protein 2 (BMP). PURPOSE: To compare the clinical, radiological outcome and complications of patients undergoing MIS-TLIF with and without BMP. OVERVIEW OF LITERATURE: BMP is an effective fusion enhancer with potential complications. Direct comparison of MIS-TLIF with and without BMP is limited to retrospective studies with short follow-up. M...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Long-Term Outcomes of Posterior Lumbar Interbody Fusion Using Stand-Alone Ray Threaded Cage for Degenerative Disk Disease: A 20-Year Follow-Up.
Authors: Baeesa SS, Medrano BG, Noriega DC Abstract STUDY DESIGN: Retrospective study. PURPOSE: To analyze outcomes of posterior lumbar interbody fusion (PLIF) stand-alone cages. OVERVIEW OF LITERATURE: PLIF for degenerative disk disease using stand-alone cages has lost its popularity owing to implant-related complications and pseudoarthrosis. METHODS: We analyzed the records of 45 patients (18 women, 27 men), operated between January 1994 and December 1996, with a mean follow-up of 18 years 3 months (20 years 3 months-22 years 3 months). Clinical outcomes were measured using visual analogue score (VAS)...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Results of Single-Staged Posterior Decompression and Circumferential Fusion Using a Transpedicular Approach to Correct a Kyphotic Deformity due to Thoracolumbar Spinal Tuberculosis.
CONCLUSIONS: The procedure of posterior decompression, fixation, and circumferential fusion using a transpedicular approach performed for thoracolumbar spinal tuberculosis is effective, safe, and excellent in correcting and maintaining kyphosis. PMID: 27994788 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Correlation of 1.5 Tesla Magnetic Resonance Imaging with Clinical and Intraoperative Findings for Lumbar Disc Herniation.
CONCLUSIONS: MRI findings strongly correlate with intraoperative features and can serve as a useful tool when planning surgery due to the accurate depiction of the morphometric features. However, the decision for surgery should be made only when detailed clinical findings in conjunction with MRI findings allow for an accurate identification of the culprit fragment and pain generators. PMID: 27994789 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

A Nationwide Retrospective Study of Opioid Management Patterns in 2,468 Patients with Spinal Pain in Korea.
CONCLUSIONS: Opioid usage patterns in patients with spinal disorders are in alignment with international guidelines for spinal pain management. Future prospective studies may address the suitability of opioids for spinal pain treatment by using appropriate objective measurement tools. PMID: 27994790 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Analysis of the Relationship between Ligamentum Flavum Thickening and Lumbar Segmental Instability, Disc Degeneration, and Facet Joint Osteoarthritis in Lumbar Spinal Stenosis.
CONCLUSIONS: LF hypertrophy development was associated with segmental instability and severe disc degeneration, severe facet joint osteoarthritis, and a sagittalized facet joint orientation. PMID: 27994791 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Prevalence of High-Riding Vertebral Artery and Morphometry of C2 Pedicles Using a Novel Computed Tomography Reconstruction Technique.
Authors: Wajanavisit W, Lertudomphonwanit T, Fuangfa P, Chanplakorn P, Kraiwattanapong C, Jaovisidha S Abstract STUDY DESIGN: Cross-sectional, matched-pair comparative study. PURPOSE: To determine whether a thin-sliced pedicular-oriented computed tomography (TPCT) scan reconstructed from an existing conventional computed tomography (CCT) scan is more accurate for identifying vertebral artery groove (VAG) anomalies than CCT. OVERVIEW OF LITERATURE: Posterior atlantoaxial transarticular screw fixation and C2 pedicle screws can cause vertebral artery (VA) injury. Two anatomic variations of VAG anomalies are as...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Bone Union Rate Following Instrumented Posterolateral Lumbar Fusion: Comparison between Demineralized Bone Matrix versus Hydroxyapatite.
CONCLUSIONS: DBM would provide noninferior outcomes compared to the HA as a fusion material for PLF, and could be a notable alternative. PMID: 27994793 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

A New Radiological Sign for Severe Angular Kyphosis: "The Baltalimani Sign".
A New Radiological Sign for Severe Angular Kyphosis: "The Baltalimani Sign". Asian Spine J. 2016 Dec;10(6):1157-1162 Authors: Atici Y, Aycan OE, Mert M, Kargin D, Albayrak A, Balioglu MB Abstract STUDY DESIGN: Retrospective diagnostic study. PURPOSE: To define a new radiological sign, "Baltalimani sign," in severe angular kyphosis (SAK) and to report its relationship with the risk of neurological deficits and deformity severity. OVERVIEW OF LITERATURE: Baltalimani sign was previously undefined in the literature. METHODS: We propose Baltalimani sign as the axial orientati...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Long-Term Effects of Untreated Adolescent Idiopathic Scoliosis: A Review of the Literature.
Authors: Weiss HR, Karavidas N, Moramarco M, Moramarco K Abstract Currently, adolescent idiopathic scoliosis (AIS) is principally regarded as benign, but some researchers have cited serious or extreme effects, including severe pain, cardiopulmonary compromise, social isolation, and even early death. Therefore, exploration of the long-term effects of AIS, the most common type of idiopathic scoliosis, is warranted. The purpose of this review was to examine the long-term studies on the natural history of AIS and/or reviews concerning the long-term effects of untreated AIS. A PubMed search was conducted using the key w...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

A Comparison of Patient-Reported Outcome Measures Following Different Treatment Approaches for Adolescents with Severe Idiopathic Scoliosis: A Systematic Review.
Authors: Bettany-Saltikov J, Weiss HR, Chockalingam N, Kandasamy G, Arnell T Abstract Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine which is usually not symptomatic and which can progress during growth and cause a surface deformity. In adulthood, if the final spinal curvature surpasses a certain critical threshold, the risk of health problems and curve progression is increased. Although surgery is usually recommended for curvatures exceeding 40° to 50° to stop curvature progression, recent reviews have shed some light on the long-term complications of such surgery and t...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Spinal Cord Stimulation in Failed Back Surgery Syndrome: Review of Clinical Use, Quality of Life and Cost-Effectiveness.
Authors: Waszak PM, Modrić M, Paturej A, Malyshev SM, Przygocka A, Garnier H, Szmuda T Abstract Failed back surgery syndrome (FBSS) is complex and recurrent chronic pain after spinal surgery. Several important patient and surgery related risk factors play roles in development of FBSS. Inadequate selection of the candidates for the spinal surgeries is one of the most crucial causes. The guidelines suggest that conservative management featuring pharmacologic approaches and rehabilitation should be introduced first. For therapy-refractory FBSS, spinal cord stimulation (SCS) is recommended in selected patients. Treatm...
Source: Asian Spine Journal - December 21, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Anatomic Considerations of Intervertebral Disc Perspective in Lumbar Posterolateral Approach via Kambin's Triangle: Cadaveric Study.
CONCLUSIONS: The trapezoidal perspective of working zone of IVD in Kambin's triangle is important and limited. This should be taken into consideration when developing the tools and instruments for posterolateral endoscopic lumbar spine surgery. PMID: 27790308 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Nitric Oxide Metabolite Concentration in Cerebrospinal Fluid: Useful as a Prognostic Marker?
CONCLUSIONS: CSF NOx concentration can be considered a specific quantitative biomarker in acute stage of SCI to predict the severity and prognosis of SCI patients. PMID: 27790309 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

A Survey of Vitamin D Status in Patients with Degenerative Diseases of the Spine.
Authors: Zolfaghari F, Faridmoayer A, Soleymani B, Taji M, Mahabadi M Abstract STUDY DESIGN: Descriptive cross-sectional study. PURPOSE: To determine the prevalence of vitamin D deficiency in patients with degenerative diseases of the spine about to undergo spinal surgery and the relations between such deficiency and potential risk factors. OVERVIEW OF LITERATURE: Vitamin D has a major role in musculoskeletal system health maintenance. Recently, studies on degenerative diseases of the spine have shown a high prevalence of vitamin D deficiency in patients undergoing spine surgery. METHODS: Serum levels o...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Serum Levels of the Inflammatory Cytokines in Patients with Lumbar Radicular Pain Due to Disc Herniation.
This study primarily aimed to evaluate the serum levels of tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-4 in patients with lumbar radiculopathy 1 and 12 months after microdiscectomy. OVERVIEW OF LITERATURE: Lumbar radiculopathy is possibly caused by inflammatory changes in the nerve root. The intraneural application of pro-inflammatory cytokines induces behavioral signs associated with pain. Anti-inflammatory cytokine treatment effectively reduces hyperalgesia. METHODS: The role of TNF-α and IL-4 in long-lasting lumbar radiculopathy was addressed. A total of 262 patients were recruited from ...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Magnetic Resonance Imaging and GeneXpert: A Rapid and Accurate Diagnostic Tool for the Management of Tuberculosis of the Spine.
CONCLUSIONS: Majority of the patients with tuberculosis of the spine can be diagnosed on the basis of a typical radiological presentation via MRI. In our study, 84.8% cases exhibited typical MRI findings. For patients presenting with atypical MRI features, a rapid and accurate diagnosis is possible by combining GeneXpert with MRI. The combined use of MRI and GeneXpert is a rapid and highly sensitive tool to diagnose tuberculosis and rifampicin resistance in patients with tuberculosis of the spine. Furthermore, we achieved a 97.9% sensitivity for the detection of Mycobacterium tuberculosis and 100% sensitivity for the detec...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Age-Related Incidence of Cervical Spondylosis in Residents of Jeju Island.
CONCLUSIONS: The incidence of cervical spondylosis and number of spondylotic segments increase, and degeneration gradually becomes more severe with age. PMID: 27790313 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions.
Authors: Elnoamany H Abstract STUDY DESIGN: Prospective cohort study. PURPOSE: To evaluate the clinical and radiological results of percutaneous selective vertebroplasty (PSV) as first-line treatment options in the setting of well-confined spinal metastases. OVERVIEW OF LITERATURE: Recent technological advances combined with innovative interventional techniques enable an alternative less invasive treatment option for many patients with malignant vertebral body infiltration. Percutaneous vertebral augmentation procedures offer less invasive but effective pain relief to many patients with symptomatic spinal m...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Validation of the ECOS-16 Questionnaire in Koreans with Osteoporosis.
CONCLUSIONS: The adapted Korean version of the ECOS-16 was successfully translated and showed acceptable measurement properties. It is considered suitable for outcome assessments in Korean patients with osteoporosis. PMID: 27790315 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

The Variation in the Lumbar Facet Joint Orientation in an Adult Asian Population and Its Relationship with the Cross-Sectional Area of the Multifidus and Erector Spinae.
CONCLUSIONS: The lumbar facet joint orientation was found to have a wide variation, particularly at the L5-S1 in the Asian adult population, and the facet joint orientation had a relationship with the CSA of the erector spinae at the L4-5. PMID: 27790316 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Impact of Rotation Correction after Brace Treatment on Prognosis in Adolescent Idiopathic Scoliosis.
Authors: Yamane K, Takigawa T, Tanaka M, Sugimoto Y, Arataki S, Ozaki T Abstract STUDY DESIGN: Level 4 retrospective review. PURPOSE: Brace treatment is the standard nonoperative treatment for adolescent idiopathic scoliosis (AIS). Rotation correction is also important, because AIS involves a rotation deformity. The purpose of this study was to evaluate the impact of rotation correction after Osaka Medical College (OMC) brace treatment on clinical outcomes in AIS. OVERVIEW OF LITERATURE: Brace treatment has a significant effect on the progression of AIS. However, few reports have examined rotation correctio...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Significance of the Pars Interarticularis in the Cortical Bone Trajectory Screw Technique: An In Vivo Insertional Torque Study.
Authors: Ninomiya K, Iwatsuki K, Ohnishi YI, Ohkawa T, Yoshimine T Abstract STUDY DESIGN: Retrospective study. PURPOSE: Cortical bone trajectory (CBT), a more medial-to-lateral and shorter path than the traditional one for spinal fusion, is thought to be effective for severely degenerated vertebrae because screws are primarily stabilized at the posterior elements. We evaluated the efficacy of this approach through in vivo insertional torque measurement. OVERVIEW OF LITERATURE: There has been only one prior in vivo study on CBT insertional torque. METHODS: Between January 2013 and April 2014, a total of ...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Predisposing Factors for Intraoperative Endplate Injury of Extreme Lateral Interbody Fusion.
CONCLUSIONS: Intraoperative endplate injury is correlated significantly with reduced BMD and taller cage height. Precise evaluation of bone quality and treatment for osteoporosis might be important and care should be taken not to choose excessively taller cage. PMID: 27790319 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Surgical Management in Elderly Patients with Tuberculous Spondylodiscitis: Ten Year Mortality Audit Study.
CONCLUSIONS: Preoperative immobility is associated with immediate postoperative mortality in elderly patients with spinal tuberculosis undergoing surgery. The findings identify preoperative immobility as a risk factor for mortality, which could contribute to a more detailed prognostic discussion between surgeon and patient before surgery. PMID: 27790320 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

C2 Body Fracture: Report of Cases Managed Conservatively by Philadelphia Collar.
CONCLUSIONS: In patients with pure C2 body fracture, non-operative management with Philadelphia neck collar is a safe and efficacious option, even in the presence of some sort of ligamentous injury. PMID: 27790321 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Role of Transpedicular Percutaneous Vertebral Biopsy for Diagnosis of Pathology in Vertebral Compression Fractures.
CONCLUSIONS: C-arm guided percutaneous transpedicular vertebral biopsy is useful in obtaining definitive histopathological diagnosis of vertebral compression fractures, especially in differentiating malignant and non-malignant vertebral compression fractures and helping plan appropriate management of patients. The rate of unexpected malignancy in vertebral compression fracture was 1.19%. PMID: 27790322 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Efficacy of TachoSil, a Fibrin-Based Hemostat, for Anterior Lumbar Spine Surgery.
CONCLUSIONS: We recommend the use of TachoSil for vessel injuries that vascular surgeons cannot suture or repair during ALF surgery. PMID: 27790323 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Associated Factors for Lumbar Degenerative Spondylolisthesis in Japanese Patients with Osteoarthritis of the Hip: A Radiographic Study.
CONCLUSIONS: Age, female sex, BMI, SS, low Crowe classification, and P-OA are independently associated factors for DS in patients with hip OA. PMID: 27790324 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Surgical Outcome of Children and Adolescents with Tethered Cord Syndrome.
Authors: Seki T, Hida K, Yano S, Sasamori T, Hamauch S, Koyanagi I, Houkin K Abstract STUDY DESIGN: Retrospective cohort study. PURPOSE: To compare long-term results of surgery with the outcomes of symptomatic and asymptomatic tethered cord syndrome (TCS) in children and adolescents and to assess the surgery duration for those with TCS. OVERVIEW OF LITERATURE: Pediatric patients with TCS continue to pose significant diagnostic and management challenges. METHODS: We retrospectively analyzed the outcomes of 31 patients (16 males, 15 females) with TCS, including 21 with lumbosacral lipoma. All were surgica...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Neurological Recovery in Two Patients with Cauda Equina Syndrome Secondary to L5 Lumbar Spine Giant Cell Tumour after Treatment with Denosumab without Surgery.
We report two patients with cauda equina syndrome (CES) secondary to L5 giant cell tumour (GCT) who achieved good neurological recovery after treatment with denosumab without surgery. The first patient was a 26-year-old man with L5 GCT causing CES who regained bowel and urinary control, muscle power improvement from grade 2 to grade 4 and Oswestry disability index (ODI) improvement from 48 to 23 after denosumab treatment. The second patient was a 25-year-old woman with L5 GCT causing CES who regained bowel and urinary control, muscle power improvement from grade 0 to grade 4 and ODI improvement from 42 to 20 after denosuma...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Challenges of Transarticular Screw Fixation in Young Children: Report of Surgical Treatment of a 5-Year-Old Patient's Unstable Os-Odontoideum.
We present the patient's history, physical examination, and radiographic findings, describe the surgical treatment and a five year follow-up, and provide a literature review. The instability was treated by halo immobilization, followed by C1-C2 transarticular screw fixation using a computed tomography-based navigation system. At the five year follow-up, the patient had made a complete recovery with solid union. The authors conclude that C1-2 transarticular screw fixation is technically possible as in a case of atlantoaxial instability in a five-year-old child. PMID: 27790327 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Ten Important Tips in Treating a Patient with Lumbar Disc Herniation.
Authors: Omidi-Kashani F, Hejrati H, Ariamanesh S Abstract Lumbar disc herniation is a common spinal disorder that usually responds favorably to conservative treatment. In a small percentage of the patients, surgical decompression is necessary. Even though lumbar discectomy constitutes the most common and easiest spine surgery globally, adverse or even catastrophic events can occur. Appropriate patient selection and effective neural decompression constitute the most important points for better surgical outcomes and avoidance of unpleasant complications. Other important tips include timely performance of magnetic re...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Vitamin D Receptor Gene, Matrix Metalloproteinase 3 Polymorphisms and the Risk of Intervertebral Disc Degeneration Susceptibility: Meta-Analysis.
Authors: Nong L, Huang Y, Zhao S, Xu N Abstract Several studies have evaluated the association between vitamin D receptor, matrix metalloproteinase 3 (MMP-3) polymorphisms and the risk of intervertebral disc degeneration susceptibility. The findings were inconsistent. This meta-analysis aimed to systematically assess the association between vitamin D receptor, MMP-3 polymorphisms and the risk of intervertebral disc degeneration susceptibility. A search of various databases was done covering all papers published until December 31th, 2014. Eight, 4, 3 studies were finally included that addressed the risk of intervert...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Thromboembolism in the Sub-Acute Phase of Spinal Cord Injury: A Systematic Review of the Literature.
Authors: Alabed S, Belci M, Van Middendorp JJ, Al Halabi A, Meagher TM Abstract To review the evidence of thromboembolism incidence and prophylaxis in the sub-acute phase of spinal cord injury (SCI) 3-6 months post injury. All observational and experimental studies with any length of follow-up and no limitations on language or publication status published up to March 2015 were included. Two review authors independently selected trials for inclusion and extracted data. Outcomes studied were incidence of pulmonary embolism (PE) and deep vein thrombosis (DVT) in the sub-acute phase of SCI. The secondary outcome was ty...
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Letter: Comparison of Posterior Lumbar Interbody Fusion and Posterolateral Lumbar Fusion in Monosegmental Vacuum Phenomenon within an Intervertebral Disc.
Authors: Viswanathan VK, Subramanian S PMID: 27790331 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Response to: Comparison of Posterior Lumbar Interbody Fusion and Posterolateral Lumbar Fusion in Monosegmental Vacuum Phenomenon within an Intervertebral Disc.
Authors: An KC, Kong GM, Park DH, Baik JM, Youn JH, Lee WS PMID: 27790332 [PubMed - in process] (Source: Asian Spine Journal)
Source: Asian Spine Journal - October 31, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Transplantation of Neural Stem Cells Cultured in Alginate Scaffold for Spinal Cord Injury in Rats.
CONCLUSIONS: Transplantation of NSCs that were cultured in an alginate scaffold led to a better clinical and histological outcome for recovery from spinal cord injury in a rat model. PMID: 27559438 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Dose Optimization for Single Intradiscal Administration of the Tumor Necrosis Factor- α Inhibitor, Etanercept, in Rat Disc Injury Models.
Dose Optimization for Single Intradiscal Administration of the Tumor Necrosis Factor-α Inhibitor, Etanercept, in Rat Disc Injury Models. Asian Spine J. 2016 Aug;10(4):619-23 Authors: Inage K, Orita S, Yamauchi K, Suzuki T, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Kanamoto H, Inoue M, Kinoshita H, Takahashi K, Ohtori S Abstract STUDY DESIGN: Experimental animal study. PURPOSE: We aimed to determine the optimal dose of a single direct injection of the tumor necrosis factor (TNF)-α inhibitor, etanercept, by using the rat model of degenerative in...
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Learning Curve Associated with Complications in Biportal Endoscopic Spinal Surgery: Challenges and Strategies.
CONCLUSIONS: BESS seemed to have a relatively short learning curve period. The overall complication rate in early learning period was 10.3%. These could be avoided by magnified regional views on an endoscope and a clear surgical field by controlling epidural bleeding. PMID: 27559440 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Accuracy of Percutaneous Lumbosacral Pedicle Screw Placement Using the Oblique Fluoroscopic View Based on Computed Tomography Evaluations.
CONCLUSIONS: Minimally invasive lumbosacral PPS placement using the conventional fluoroscopic technique carries an increased risk of inaccurate screw placement and resultant neurological deficits, compared with that of the open procedure. Inaccuracy tended to be distributed between medial and lateral perforations of the L5 pedicle, as a result of pedicle morphology and the PPS pathway. Oblique fluoroscopic views, based on CT measurement, may allow accurate PPS insertion with a shorter fluoroscopy time. PMID: 27559441 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Fixation Strength of Caudal Pedicle Screws after Posterior Lumbar Interbody Fusion with the Modified Cortical Bone Trajectory Screw Method.
CONCLUSIONS: Fixation strength of the caudal screw after floating PLIF with this modified CBT screw technique was sufficiently acceptable. Fixation strength after the lumbosacral procedure was not. PMID: 27559442 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Significance of Coronal Proset Magnetic Resonance Imaging to Detect Hidden Zone of the Mid-Zone Stenosis in the Lumbar Spine and Morphometric Analysis of the Mid-Zone Stenosis.
Authors: Ahn HS, Son WS, Shin JH, Ahn MW, Lee GW Abstract STUDY DESIGN: Retrospective exploratory imaging study. PURPOSE: To investigate the significance of the coronal magnetic resonance imaging (MRI) using Proset technique to detect the hidden zone in patients with mid-zone stenosis by comparing with conventional axial and sagittal MRI and to explore the morphologic characteristic patterns of the mid-zone stenosis. OVERVIEW OF LITERATURE: Despite advancements in diagnostic modalities such as computed tomography and MRI, stenotic lesions under the pedicle and pars interarticularis, also called the mid-zone...
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Ankylosing Spondylitis: Patterns of Spinal Injury and Treatment Outcomes.
CONCLUSIONS: Nonsurgical treatment can be considered especially in the elderly patients with AS and spinal trauma but without instability or major neurological deficits. The nonfusion rate in conservatively treated patients is low. When treatment is selected for patients with spinal fractures and AS, the pattern of injury must be considered and the need for individualized treatment is paramount. PMID: 27559444 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Agreement on the Level Selection in Laminoplasty among Experienced Surgeons: A Survey-Based Study.
CONCLUSIONS: The degree of agreement for level selection of LP was not high even though experienced surgeons would choose the opening segments on the basis of same criteria. These results suggest that more specific guidelines in determination of levels for LP should be required to decrease unnecessary wide decompression according to individual variance. PMID: 27559445 [PubMed] (Source: Asian Spine Journal)
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

Transforaminal Percutaneous Endoscopic Discectomy for Lumbar Disc Herniation in Parkinson's Disease: A Case-Control Study.
Authors: Kapetanakis S, Giovannopoulou E, Charitoudis G, Kazakos K Abstract STUDY DESIGN: A case-control study. PURPOSE: To investigate the effectiveness of transforaminal percutaneous endoscopic discectomy (TPED) in Parkinson's disease (PD). OVERVIEW OF LITERATURE: Patients with PD frequently suffer from radiculopathy and low back pain. Additionally, they demonstrate higher complication rates after open spine surgery. However, the clinical outcome of minimally invasive techniques for lumbar discectomy, such as TPED, have not been established for this population. METHODS: Patients diagnosed with lumbar ...
Source: Asian Spine Journal - August 27, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research