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Exploring on the elderly health management model in tropic area
Publication date: Available online 15 June 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Yan Song, Jie-Ge Jiao, Ze-Jun Chen In this article, based on the characteristics of tropical area, we analyze the beneficial and the disadvantage of tropical area to human health, points out the existing problems in elderly health management pattern in the tropics area, accordingly we discuss how to establish tropical characterized elderly health management, and put forward constructive suggestions. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - June 16, 2017 Category: Tropical Medicine Source Type: research

Comparison of phenolic components and biological activities of two Centaurea sp. obtained by three extraction techniques
This study confirms that ultrasonic extraction may be an ideal, simple and rapid method to obtain polyphenol-rich extracts have antioxidant as well as antibacterial activity from both Centaurea species especially from C. amaena. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - June 16, 2017 Category: Tropical Medicine Source Type: research

Matrine inhibits bladder cancer cell growth and invasion in  vitro through PI3K/AKT signaling pathway: An experimental study
Conclusions Matrine can inhibit bladder cancer cell proliferation and invasion in vitro and regulate the expression of cell cycle-inhibiting molecules and invasion-related genes through PI3K/AKT signaling pathway. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 25, 2017 Category: Tropical Medicine Source Type: research

MiR-200a and miR-200b target PTEN to regulate the endometrial cancer cell growth in  vitro
Conclusion miR-200a and miR-200b can promote the endometrial cancer cell growth in vitro by targeted inhibition of PTEN gene expression. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 24, 2017 Category: Tropical Medicine Source Type: research

Helianthus tuberosus (Jerusalem artichoke) tubers improve glucose tolerance and hepatic lipid profile in rats fed a high-fat diet
Conclusions These results indicate that HT tubers have anti-fatty liver effects based on improvements in glucose tolerance and the hepatic lipid profile. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 19, 2017 Category: Tropical Medicine Source Type: research

Genetic diversity and phylogenetic analysis of EG95 sequences of Echinococcus granulosus: Implications for EG95 vaccine application
Conclusions This study reveals the genetic variability of EG95 sequences in different E. granulosus isolates, and proposed that more vaccination trials would be needed to test the effectiveness of current EG95 vaccine against distinct isolates in different countries. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 19, 2017 Category: Tropical Medicine Source Type: research

Identification of novel biomarkers for adult-onset-immunodeficiency (AOID) syndrome using serum proteomics
Conclusions The comparison of serum proteins between the three groups revealed three candidates which are related to chronic inflammatory diseases. Haptoglobin and transthyretin biomarkers could be applied in clinical assessment for monitor of disease outcome, including for the study of AOID pathogenesis. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 19, 2017 Category: Tropical Medicine Source Type: research

Ethnobotanical profiling of the medicinal flora of Kotli, Azad Jammu and Kashmir, Pakistan: Empirical reflections on multinomial logit specifications
Conclusions The results of the study emphasize the need to create awareness among the local communities about the conservation status of plant species in order to maintain a sustainable resource of plant-derived materials into the future. The novel econometric approach employed in this study adds a new insightful methodology to the existing body of literature in the field of ethnobotany. We strongly recommend conservation measures, alongside phytochemical and pharmacological studies on the useful plant species identified in this study in order to ensure their sustainable and effective utilization. (Source: Asian Pacific Jo...
Source: Asian Pacific Journal of Tropical Medicine - May 19, 2017 Category: Tropical Medicine Source Type: research

Relationship between catecholamine level and gene polymorphism of β1 adrenergic receptor G1165C in children with EV71 infection in hand foot and mouth disease
Conclusions As the disease gets worse, the plasma norepinephrine level has a rising trend in children with EV71 infection in HFMD, which is an important indicator to evaluate the progress of the disease. However, the gene polymorphism of β1 adrenergic receptor G1165C have no significant correlation, not only with the susceptibility and severity of EV71 infection in hand, foot and mouth disease, but also with the levels of catecholamine. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 19, 2017 Category: Tropical Medicine Source Type: research

Bougainvillea spectabilis flowers extract protects against the rotenone-induced toxicity
Conclusions These data indicate that B. spectabilis flowers extracts exert protective effect against the toxic effects of rotenone on brain, liver and kidney. B. spectabilis flowers extracts decreased brain lipid peroxidation and prevented neuronal death due to rotenone and might thus prove the value in treatment of Parkinson’s disease. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 19, 2017 Category: Tropical Medicine Source Type: research

Pyrrolidine dithiocarbamate alleviates the anti-tuberculosis drug-induced liver injury through JAK2/STAT3 signaling pathway: An experimental study
Conclusions PDTC can inhibit the inflammation and oxidative stress mediated by JAK2/STAT3 signaling pathway to alleviate the anti-tuberculosis drug-induced liver injury. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 19, 2017 Category: Tropical Medicine Source Type: research

Matrine inhibits bladder cancer cell growth and invasion in vitro through PI3K/AKT signaling pathway: An experimental study
Conclusions Matrine can inhibit bladder cancer cell proliferation and invasion in vitro and regulate the expression of cell cycle-inhibiting molecules and invasion-related genes through PI3K/AKT signaling pathway. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research

Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis
Conclusions RA impeded the progression of liver fibrosis through inhibition of HSCs activation/proliferation and induction of apoptosis with preservation of hepatic architecture. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research

Preoperative application of combination of portal venous injection of donor spleen cells and intraperitoneal injection of rapamycin prolongs the survival of cardiac allografts in mice
Conclusions Preoperative application of combination of PVIDSC and rapamycin significantly prolonged the survival time of cardiac allografts in mice but not in mice pre-sensitized by skin grafting. This may be explained by the fact that combination of PVIDSC and rapamycin inhibited the cellular immune response and induced the expression of IL-10 from Tr1 cells and CD4+CD25+FoxP3+ regulatory T cells. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research

Prevalence and risk factors of Blastocystis infection among underprivileged communities in rural Malaysia
Conclusions Blastocystosis is revealed through this study to be still prevalent among Orang Asli communities in rural Malaysia. The two main approaches that should be implemented by the public health authority in battling this infection would be the screening of other family members and giving treatment to the infected individuals. Moreover, it is imperative for health education on good personal and food hygiene practices are provided in order to reduce the morbidity and transmission of Blastocystis infection among the Orang Asli in their communities meaningfully. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research