Antimicrobial resistance and underlying mechanisms in Staphylococcus aureus isolates
Conclusions In conclusion, it was determined that the isolates were resistant to different classes of antimicrobials at varying rates and resistance was mediated by different genetic mechanisms. Therefore, continuous monitoring of resistance in S . aureus strains is necessary to control their resistance for clinically important antimicrobials. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Bacteriocin-like inhibitory substance (BLIS) activity of Streptococcus macedonicus MBF10-2 and its synergistic action in combination with antibiotics
Conclusion Combination of some BLIS(MBF10-2) active fractions with antibiotics (ampicillin, tetracycline or kanamycin) could demonstrate synergistic activities against certain Gram-positive species. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

An overview on cardioprotective and anti-diabetic effects of thymoquinone
Publication date: Available online 9 October 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Tahereh Farkhondeh, Saeed Samarghandian, Abasalt Borji Thymoquinone (TQ), one of the active components of Nigella sativa exhibited to have many biological effects. Several beneficial effects of TQ such as its antidiabetic, antioxidant, anticancer, hypolipidemic, and anti-inflammatory activities have been recognized. The present review focuses on the findings of recent studies on the protective effects of TQ against cardiovascular diseases. In the current review, we additionally concluded that TQ may be therap...
Source: Asian Pacific Journal of Tropical Medicine - October 10, 2017 Category: Tropical Medicine Source Type: research

Elevated serum prostaglandin E2 predicts the risk of infection in hepatitis B virus-related acute-on-chronic liver failure patients
Conclusions Serum PGE2 is associated with the susceptibility to secondary infections for patients with ACLF. Increased PGE2 serum levels may serve as a potential biomarker for developing infections in ACLF patients. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 8, 2017 Category: Tropical Medicine Source Type: research

Relationship between abnormal vagus nerve tension and basal ganglia cerebral infarction induced paroxysmal atrial fibrillation
Conclusion Elderly patients with basal ganglia infarction have high incidence of PAF. Sympathetic nerve damage in cerebral basal ganglia, increased vagal tension and cardiac vagal tension are the direct causes of PAF. The results indicates that the increased central vagal nerve tension mediated PAF probably is an indication of supplying sympathetic neurotransmitter or cardiac vagal denervation treatment. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 28, 2017 Category: Tropical Medicine Source Type: research

Plasmodium falciparum found in the bone marrow of a child in Manado City, East Indonesia: a case report
Publication date: Available online 23 September 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Suryadi N.N. Tatura, Stefanus Gunawan, Janno Bernadus, Sianne Sandjoto In Indonesia, there are at least 1.3 million cases of malaria each year and Plasmodium falciparum appears to be the most common Plasmodium. The finding of Plasmodium is important for the diagnosis and management of malaria. This is a case of a 4-year-and-9-month-old male who lived in Manado, East Indonesia. He presented with a prolonged fever, was pale in appearance, and was easily fatigued over the last 3 weeks. Hepato-splenomegaly wa...
Source: Asian Pacific Journal of Tropical Medicine - September 24, 2017 Category: Tropical Medicine Source Type: research

Synergists action of piperonyl butoxide and S,S,S-tributyl phosphorotrithioate on toxicity of carbamate insecticides against Blattella germanica
Conclusions In most of these strains, resistance to bendiocarb and carbaryl is completely eliminated by DEF, showing a very high role of estraze enzymes in resistance to bendiocarb and carbaryl. But in most strains PBO does not remove the resistance because other mechanisms, such as reduced cuticle penetration and insensitivity to the acetylcholine esterase enzyme, may be involved. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 23, 2017 Category: Tropical Medicine Source Type: research

Neuron-protective effect of subanesthestic-dosage ketamine on mice of Parkinson's disease
Conclusions The subanesthestic-dosage ketamine has some protective effects on the coordinating ability of movement and cognitive ability of Parkinson's disease mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. This is probably due to that the autophagy activity of cells is activated by subanesthestic-dosage ketamine and that the neurons are protected. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 23, 2017 Category: Tropical Medicine Source Type: research

Antifungal, molluscicidal and larvicidal assessment of anemonin and Clematis flammula L. extracts against mollusc Galba truncatula, intermediate host of Fasciola hepatica in Tunisia
Conclusions This study emphasizes the important molluscicidal and antiparasitic effects of flower ethyl acetate extracts and anemonin compound as well as the considerable antifungal activities of methanolic extracts. These results improve the therapeutic virtues of C. flammula aerial part extracts. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 21, 2017 Category: Tropical Medicine Source Type: research

Comparison of hypotensive, diuretic and renal effects between cladodes of Opuntia ficus-indica and furosemide
Conclusions Gel and aqueous extract of Opuntia ficus-indica cladode have a significant diuretic effect on rats, and the lyophilized extract has a diuretic and hypotensive effect on normotensive rabbits without deterioration in renal function test. Additional studies on active ingredients are essential to pave the way for clinical studies on diuretic and hypotensive effect of the plant. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

A review of five traditionally used anti-diabetic plants of Bangladesh and their pharmacological activities
This study has focused on five plants which are Andrographis paniculata, Ageratum conyzoides, Swertia chirata, Terminalia arjuna, and Azadirachta indica to find out their traditional formulation as anti-diabetic medicine and their pharmacological activity has also been explored through literature search. The available information about traditional anti-diabetic uses of these plants and their pharmacological activities were collected from various electronic sources like Pubmed, SciFinder, Elsevier, Springer, Scopus, Scirus, Science Direct, Google Scholar and Web of Science apart from these locally available books and peer r...
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Food intake regulation by leptin: Mechanisms mediating gluconeogenesis and energy expenditure
Publication date: Available online 18 September 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Zulfia Hussain, Junaid Ali Khan Regulation of blood glucose levels and body fat is critical for survival. Leptin circulates freely in blood and controls body weight and food intake mainly through hypothalamic receptors and regulates glucose metabolism in the liver both directly through leptin receptors and indirectly via the hypothalamic receptors of central nervous system. Leptin affects food intake regulation and eventually glucose metabolism, lipometabolism, endocrine and immune functions, reproductive f...
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Giardia duodenalis infection among rural communities in Yemen: a community-based assessment of the prevalence and associated risk factors
Conclusions The study reveals that Giardia infection is still prevalent among rural communities in Yemen. The provision of clean and safe drinking water, proper sanitation, and health education regarding personal hygiene practices, particularly handwashing, as well as identifying and treating infected family members is imperative and these interventions should be considered in a strategy to control intestinal parasites among these communities in order to curtail the transmission and morbidity caused by G. duodenalis. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Neuron-protective effect of subanesthestic-dosage ketamine on mice of Parkinson ’s disease
Conclusions The subanesthestic-dosage ketamine has some protective effects on the coordinating ability of movement and cognitive ability of Parkinson's disease mice induced by 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine. This is probably due to that the autophagy activity of cells is activated by subanesthestic-dosage ketamine and that the neurons are protected. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Morphological characteristics associated with rupture risk of multiple intracranial aneurysms
Conclusions IAs located in the ICA are associated with a negative risk of rupture, while high AR (>1.01), SR1 (>1.48) or SR2 (>1.40) are risk factors for multiple IAs rupture. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research