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Phytochemical analysis and biological activities of Hertia cheirifolia L. roots extracts
Conclusion The ethyl acetate extract was found to be selectively antioxidant and antimicrobial. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Expression of vimentin and glial fibrillary acidic protein in central nervous system development of rats
Conclusion Our data demonstrate for the first time that the expression of Vim and GFAP in the rat's CNS during development. This data may provide a foundation for the further mechanistic studies of these two main intermediate filaments during development of CNS. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Development of a mouse model of arecoline-induced oral mucosal fibrosis
Conclusions An OSF model involving mice can be rapidly induced by drinking a high-dose of arecoline. OSF angiogenic changes in mice primarily decrease and collagen accumulation is mainly collagen type I. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Rescue effects of aqueous seed extracts of Foeniculum vulgare and Carum carvi against cadmium-induced hepatic, renal and gonadal damage in female albino rats
Conclusions Both FVE and CCE could be used as efficient treatments for liver and kidney against CC intoxication. Moreover, FVE could be utilized as a potent treatment to protect and improve female fertility from cadmium intoxication. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Effects of 8-Hydroxyisocapnolactone-2-3-diol and friedelin on mast cells degranulation
Conclusion These results exhibit the promising of 8-hydroxyisocapnolactone-2-3-diol is a potential parent structure for developing a MCs stabilizer. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Antibiofilm activity of α-mangostin extracted from Garcinia mangostana L. against Staphylococcus aureus
Conclusions Our results provide evidence that the isolated AMG has inhibitory activity against biofilm formation by S. aureus, including MRSA. Thus, isolated AMG proposes a high potential to develop a novel phytopharmaceutical for the treatment of MRSA. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Pharmacological evaluation of smooth muscle relaxant and cardiac-modulation potential of Phyla nodiflora in ex-vivo and in-vivo experiments
Conclusion This study suggests the blockage of calcium channel in the smooth muscles as a pharmacological application to make usage of P . nodiflora in the management of diarrhea, asthma and hypotensive effect. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Reverse effect of curcumin on CDDP-induced drug-resistance via Keap1/p62-Nrf2 signaling in A549/CDDP cell
Conclusions The present findings demonstrate that CDDP promotes abnormal activation of Nrf2 pathway and autophagy, leading to drug resistance of A549/CDDP cell. Curcumin attenuates this process and combat drug-resistance through its potent activation on Keap1 transcription, which is essential for interplay between oxidative stress induced Nrf2 activation and autophagy/apoptosis switch. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Some pathogenic characters of paratyphoid Salmonella enterica strains isolated from poultry
Conclusion Our results show that paratyphoid Salmonella strains with several characters of pathogenicity, that may be cause of severe pathology in animals and humans, are circulating among poultry. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Faunal data and envenomation emergency first aid of cone snails (Conus spp.) in Qeshm Island, the Persian Gulf
Conclusions Envenomation can cause various symptoms ranging from minor local pain to systemic paralysis and death due to respiratory failure. We recommend an awareness programme for the seashore visiting public. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Natural compounds and extracts from Mexican medicinal plants with anti-leishmaniasis activity: An update
Publication date: Available online 2 November 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Gabriel Alfonso Gutiérrez-Rebolledo, Susan Drier-Jonas, María Adelina Jiménez-Arellanes Leishmaniasis is considered as an emerging, uncontrolled disease and is endemic in 98 countries. Annually, about 2 million cases of cutaneous and 500000 cases of visceral-type leishmaniasis are recorded and 60000 persons died from the disease. In Mexico, cutaneous leishmaniasis is known as chiclero's ulcer and is reported in 22 states, it is considered as a health problem. For its treatment, pentavalent antimonial drug...
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Electrophysiological changes of autonomic cells in left ventricular outflow tract in guinea pigs with iron deficiency anemia complicated with chronic heart failure
Conclusions There are electrophysiological abnormalities of the left ventricular outflow tract in guinea pigs with iron deficiency anemia complicated with heart failure. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

An atypical case of disseminated cutaneous leishmaniasis due to Leishmania peruviana in the valleys of Ancash-Peru
In conclusion, the atypical presentation of this disease may be related to the presence of an uncommon parasite strain or host immune deficiencies. The molecular identification of the etiology for disseminated leishmaniasis, will allow a better understanding of the presentation and proper treatment, as well as associated risk factors. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Pattern of hepatitis C virus genotypes and subtypes circulating in war-stricken Khyber Pakhtunkhwa, Pakistan: Review of published literature
Publication date: Available online 7 November 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Abdul Waheed Khan, Sadia Nawab, Zeeshan Nasim, Abdul Haleem Khan, Syed Ishfaq Ahmad, Fazli Zahir, Israr Ud Din Infection due to hepatitis C virus (HCV) is a major cause of fibrosis and hepatocellular carcinoma in Pakistan. In the current review, pattern of HCV genotypes and subtypes in Khyber Pakhtunkhwa province was ascertained in light of the available literature. After thorough analysis, genotype 3 (58.27%) was determined to be the leading HCV genotype, followed by genotypes 2 (12.39%), 1 (9.54%) and ...
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Polyphenolic content, in  vitro antioxidant activity and chemical composition of extract from Nephelium lappaceum L. (Mexican rambutan) husk
Conclusions Rambutan husk cultivated in Mexico is a promising source for the recovery of added value bioactive compounds with antioxidant activity, which have potential applications as bioactive antioxidant agents for the treatment of diseases. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research