IgG antibodies mediated gold nanoparticles conjugated to methotrexate as targeted chemotherapy for lung cancer
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):384-396. doi: 10.1080/21691401.2023.2242419.ABSTRACTVincamine, a natural chemical, was used as a reducing agent in the synthesis of IgG antibodies mediated biogenic gold nanoparticles (IgGAuNPs). Eventually, the synthesised IgGAuNPs were bioconjugated with the chemotherapeutic drug methotrexate (MTX-IgGAuNPs). The IgG isotype can target cancer cells through polymorphic Fc gamma receptors (FcγRs) and have therapeutic effects. They can restrict cell division by inhibiting different intracellular signal transduction pathways and activating NK cells and macrophages through antibo...
Source: Artificial Cells, Nanomedicine and Biotechnology - August 7, 2023 Category: Biotechnology Authors: Asad Syed Abu Baker Mohamed Mohany Abdallah M Elgorban Mohd Sajid Khan Salim S Al-Rejaie Source Type: research

An impedance flow cytometry with integrated dual microneedle for electrical properties characterization of single cell
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):371-383. doi: 10.1080/21691401.2023.2239274.ABSTRACTElectrical characteristics of living cells have been proven to reveal important details about their internal structure, charge distribution and composition changes in the cell membrane, as well as the extracellular context. An impedance flow cytometry is a common approach to determine the electrical properties of a cell, having the advantage of label-free and high throughput. However, the current techniques are complex and costly for the fabrication process. For that reason, we introduce an integrated dual microneedle-microch...
Source: Artificial Cells, Nanomedicine and Biotechnology - August 7, 2023 Category: Biotechnology Authors: Muhammad Asraf Mansor Mohd Ridzuan Ahmad Michal Petr ů Seyed Saeid Rahimian Koloor Source Type: research

IgG antibodies mediated gold nanoparticles conjugated to methotrexate as targeted chemotherapy for lung cancer
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):384-396. doi: 10.1080/21691401.2023.2242419.ABSTRACTVincamine, a natural chemical, was used as a reducing agent in the synthesis of IgG antibodies mediated biogenic gold nanoparticles (IgGAuNPs). Eventually, the synthesised IgGAuNPs were bioconjugated with the chemotherapeutic drug methotrexate (MTX-IgGAuNPs). The IgG isotype can target cancer cells through polymorphic Fc gamma receptors (FcγRs) and have therapeutic effects. They can restrict cell division by inhibiting different intracellular signal transduction pathways and activating NK cells and macrophages through antibo...
Source: Artificial Cells, Nanomedicine and Biotechnology - August 7, 2023 Category: Biotechnology Authors: Asad Syed Abu Baker Mohamed Mohany Abdallah M Elgorban Mohd Sajid Khan Salim S Al-Rejaie Source Type: research

Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for < em > in  vitro < /em > cell migration
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):346-360. doi: 10.1080/21691401.2023.2237534.ABSTRACTExtracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally secreted EVs are limited, liposomes with different physicochemical properties, such as 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) and linoleic acid (LA) with modifications have been formulated to improve EVs secretion for in vitro wound healing. Various analyses, including dynamic light scattering (DLS) and transmission electron microscop...
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Jzit Weii Chen Fong Fong Liew Hsiao Wei Tan Misni Misran Ivy Chung Source Type: research

Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells
CONCLUSION: Treatment of LC cells with Cur-NPs decreased cell proliferation, migration, and angiogenesis, and induced cell death by promoting the proapoptotic pathway.PMID:37524306 | DOI:10.1080/21691401.2023.2238756 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Steve Harakeh Saber H Saber Rajaa Al-Raddadi Turki Alamri Soad Al-Jaouni Mohammed Qari Yousef Qari Shafiul Haque Ayat Zawawi Soad S Ali Zakaria Y Abd Elmageed Shaker Mousa Source Type: research

Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for < em > in  vitro < /em > cell migration
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):346-360. doi: 10.1080/21691401.2023.2237534.ABSTRACTExtracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally secreted EVs are limited, liposomes with different physicochemical properties, such as 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) and linoleic acid (LA) with modifications have been formulated to improve EVs secretion for in vitro wound healing. Various analyses, including dynamic light scattering (DLS) and transmission electron microscop...
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Jzit Weii Chen Fong Fong Liew Hsiao Wei Tan Misni Misran Ivy Chung Source Type: research

Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells
CONCLUSION: Treatment of LC cells with Cur-NPs decreased cell proliferation, migration, and angiogenesis, and induced cell death by promoting the proapoptotic pathway.PMID:37524306 | DOI:10.1080/21691401.2023.2238756 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Steve Harakeh Saber H Saber Rajaa Al-Raddadi Turki Alamri Soad Al-Jaouni Mohammed Qari Yousef Qari Shafiul Haque Ayat Zawawi Soad S Ali Zakaria Y Abd Elmageed Shaker Mousa Source Type: research

Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for < em > in  vitro < /em > cell migration
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):346-360. doi: 10.1080/21691401.2023.2237534.ABSTRACTExtracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally secreted EVs are limited, liposomes with different physicochemical properties, such as 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) and linoleic acid (LA) with modifications have been formulated to improve EVs secretion for in vitro wound healing. Various analyses, including dynamic light scattering (DLS) and transmission electron microscop...
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Jzit Weii Chen Fong Fong Liew Hsiao Wei Tan Misni Misran Ivy Chung Source Type: research

Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells
CONCLUSION: Treatment of LC cells with Cur-NPs decreased cell proliferation, migration, and angiogenesis, and induced cell death by promoting the proapoptotic pathway.PMID:37524306 | DOI:10.1080/21691401.2023.2238756 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Steve Harakeh Saber H Saber Rajaa Al-Raddadi Turki Alamri Soad Al-Jaouni Mohammed Qari Yousef Qari Shafiul Haque Ayat Zawawi Soad S Ali Zakaria Y Abd Elmageed Shaker Mousa Source Type: research

Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for < em > in  vitro < /em > cell migration
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):346-360. doi: 10.1080/21691401.2023.2237534.ABSTRACTExtracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally secreted EVs are limited, liposomes with different physicochemical properties, such as 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) and linoleic acid (LA) with modifications have been formulated to improve EVs secretion for in vitro wound healing. Various analyses, including dynamic light scattering (DLS) and transmission electron microscop...
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Jzit Weii Chen Fong Fong Liew Hsiao Wei Tan Misni Misran Ivy Chung Source Type: research

Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells
CONCLUSION: Treatment of LC cells with Cur-NPs decreased cell proliferation, migration, and angiogenesis, and induced cell death by promoting the proapoptotic pathway.PMID:37524306 | DOI:10.1080/21691401.2023.2238756 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Steve Harakeh Saber H Saber Rajaa Al-Raddadi Turki Alamri Soad Al-Jaouni Mohammed Qari Yousef Qari Shafiul Haque Ayat Zawawi Soad S Ali Zakaria Y Abd Elmageed Shaker Mousa Source Type: research

Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for < em > in  vitro < /em > cell migration
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):346-360. doi: 10.1080/21691401.2023.2237534.ABSTRACTExtracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally secreted EVs are limited, liposomes with different physicochemical properties, such as 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) and linoleic acid (LA) with modifications have been formulated to improve EVs secretion for in vitro wound healing. Various analyses, including dynamic light scattering (DLS) and transmission electron microscop...
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Jzit Weii Chen Fong Fong Liew Hsiao Wei Tan Misni Misran Ivy Chung Source Type: research

Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells
CONCLUSION: Treatment of LC cells with Cur-NPs decreased cell proliferation, migration, and angiogenesis, and induced cell death by promoting the proapoptotic pathway.PMID:37524306 | DOI:10.1080/21691401.2023.2238756 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Steve Harakeh Saber H Saber Rajaa Al-Raddadi Turki Alamri Soad Al-Jaouni Mohammed Qari Yousef Qari Shafiul Haque Ayat Zawawi Soad S Ali Zakaria Y Abd Elmageed Shaker Mousa Source Type: research

Cholesterol-linoleic acid liposomes induced extracellular vesicles secretion from immortalized adipose-derived mesenchymal stem cells for < em > in  vitro < /em > cell migration
Artif Cells Nanomed Biotechnol. 2023 Dec;51(1):346-360. doi: 10.1080/21691401.2023.2237534.ABSTRACTExtracellular vesicles (EVs) are small vesicles that are naturally released by cells and play a crucial role in cell-to-cell communication, tissue repair and regeneration. As naturally secreted EVs are limited, liposomes with different physicochemical properties, such as 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) and linoleic acid (LA) with modifications have been formulated to improve EVs secretion for in vitro wound healing. Various analyses, including dynamic light scattering (DLS) and transmission electron microscop...
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Jzit Weii Chen Fong Fong Liew Hsiao Wei Tan Misni Misran Ivy Chung Source Type: research

Novel curcumin nanoformulation induces apoptosis, and reduces migration and angiogenesis in liver cancer cells
CONCLUSION: Treatment of LC cells with Cur-NPs decreased cell proliferation, migration, and angiogenesis, and induced cell death by promoting the proapoptotic pathway.PMID:37524306 | DOI:10.1080/21691401.2023.2238756 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - July 31, 2023 Category: Biotechnology Authors: Steve Harakeh Saber H Saber Rajaa Al-Raddadi Turki Alamri Soad Al-Jaouni Mohammed Qari Yousef Qari Shafiul Haque Ayat Zawawi Soad S Ali Zakaria Y Abd Elmageed Shaker Mousa Source Type: research