Arterial Inflammation Detected With 18F ‐Fluorodeoxyglucose–Positron Emission Tomography in Rheumatoid Arthritis
ConclusionTraditional CV risk factors and RA disease characteristics (rheumatoid nodules and the Disease Activity Score in 28 joints using the C‐reactive protein level in anti‐CCP antibody–positive individuals) were independently associated with ascending aortic FDG uptake in RA patients without clinical CVD. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 1, 2017 Category: Rheumatology Authors: Laura Geraldino ‐Pardilla, Afshin Zartoshti, Ayse Bag Ozbek, Jon T. Giles, Richard Weinberg, Mona Kinkhabwala, Sabahat Bokhari, Joan M. Bathon Tags: Original Article Source Type: research
Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging
ConclusionOur findings indicate that increased numbers of small to medium‐sized DRG neurons respond to mechanical stimuli 8 weeks after DMM surgery, suggesting that nociceptors have become sensitized by lowering the response threshold. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 1, 2017 Category: Rheumatology Authors: Rachel E. Miller, Yu Shin Kim, Phuong B. Tran, Shingo Ishihara, Xinzhong Dong, Richard J. Miller, Anne ‐Marie Malfait Tags: Original Article Source Type: research
Marginal jawbone loss is associated with onset of rheumatoid arthritis and is related to plasma level of receptor activator of nuclear factor kappa ‐B ligand (RANKL)
ConclusionsMarginal jawbone loss preceded clinical onset of symptoms of RA but the difference was only manifested in non‐smokers. Moreover, pre‐symptomatic RA‐individuals, who were RANKL positive, displayed a significantly higher degree of marginal jawbone loss, particularly in ACPA positive individuals.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 1, 2017 Category: Rheumatology Authors: Elin Kindstedt, Linda Johansson, Py Palmqvist, Cecilia Koskinen Holm, Heidi Kokkonen, Ingegerd Johansson, Solbritt Rantap ää Dahlqvist, Pernilla Lundberg Tags: Full Length Source Type: research
Weight change in the early rheumatoid arthritis period and risk for subsequent mortality among women with RA and matched comparators
ConclusionSevere weight loss during the early RA period was associated with increased subsequent mortality risk for women with and without RA. These results extend prior observations by including non‐RA comparators and finding no protective association between weight gain and mortality, arguing against an RA‐specific obesity paradox for mortality.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 30, 2017 Category: Rheumatology Authors: Jeffrey A. Sparks, Shun ‐Chiao Chang, Uyen‐Sa Nguyen, Medha Barbhaiya, Sara K. Tedeschi, Bing Lu, David J. Kreps, Karen H. Costenbader, Yuqing Zhang, Hyon K. Choi, Elizabeth W. Karlson Tags: Full Length Source Type: research
Higher Coronary Plaque Burden in Psoriatic Arthritis is Independent of Metabolic Syndrome and Associated with Underlying Disease Severity
ConclusionsPsA is associated with accelerated coronary plaque formation, particularly mixed plaques, independent of metabolic disease. Psoriatic disease activity and severity may predict coronary plaque burden better than traditional risk factors.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 29, 2017 Category: Rheumatology Authors: Agnes Szentpetery, Gerard M. Healy, Darragh Brady, Muhammad Haroon, Phil Gallagher, Ciaran E. Redmond, Hannah Fleming, John Duignan, Jonathan D. Dodd, Oliver FitzGerald Tags: Full Length Source Type: research
Editorial: Ratiometric Optical Imaging of Subclinical Inflammation With a Thrombin ‐Cleavable Probe: A Future Tool for the In Vivo Visualization of Clinically Silent Synovitis?
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 29, 2017 Category: Rheumatology Authors: Katalin Mikecz Tags: Editorial Source Type: research
Detection of Subclinical Arthritis in Mice by a Thrombin Receptor–Derived Imaging Agent
ConclusionRACPPNleTPRSFL activation detects established experimental arthritis, and the detection of inflammation by RACPPNleTPRSFL on day 1 of serum‐transfer arthritis correlates with disease progression. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 29, 2017 Category: Rheumatology Authors: Beth Friedman, Michael A. Whitney, Elamprakash N. Savariar, Christa Caneda, Paul Steinbach, Qing Xiong, Dina V. Hingorani, Jessica Crisp, Stephen R. Adams, Michael Kenner, Csilla N. Lippert, Quyen T. Nguyen, Monica Guma, Roger Y. Tsien, Maripat Corr Tags: Original Article Source Type: research
Hard palate hyperpigmentation —a rare side effect of antimalarials
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Karin Manger, Ulrich Streitberg, Gerhard Seitz, Arnd Kleyer, Bernhard Manger Tags: Clinical Images Source Type: research
Reply
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Natalia S. Harasymowicz, Nick D. Clement, Richard Burnett, Asim Azfer, Donald M. Salter, A. Hamish W. R. Simpson Tags: Letters Source Type: research
Clinical Images: Hard palate hyperpigmentation —a rare side effect of antimalarials
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Karin Manger, Ulrich Streitberg, Gerhard Seitz, Arnd Kleyer, Bernhard Manger Tags: Clinicopathologic Conference Source Type: research
Reply
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: J érémie Dion, Nathalie Costedoat‐Chalumeau, Jean‐Charles Piette Tags: Letters Source Type: research
Organ involvement pattern suggests subgroups within relapsing polychondritis: comment on the article by Dion et al
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Jun Shimizu, Yoshihisa Yamano, Kazuo Yudoh, Noboru Suzuki Tags: Letters Source Type: research
Reply
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Xavier Pu échal, Christian Pagnoux, Loïc Guillevin, Tags: Letters Source Type: research
Does the revised definition of eosinophilic granulomatosis with polyangiitis (Churg ‐Strauss) indicate the need for a new treatment? Comment on the article by Puéchal et al
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Ilya Smitienko, Pavel Novikov, Sergey Moiseev Tags: Letters Source Type: research
Myogenic Progenitor Cells Exhibit Type I Interferon –Driven Proangiogenic Properties and Molecular Signature During Juvenile Dermatomyositis
ConclusionThese results demonstrate a new type I IFN pathway in JDM that activates the production of angiogenic effectors by MPCs, triggering their proangiogenic function to promote vessel recovery and muscle reconstruction. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - November 28, 2017 Category: Rheumatology Authors: Cyril Gitiaux, Claire Latroche, Mich èle Weiss‐Gayet, Mathieu P. Rodero, Darragh Duffy, Brigitte Bader‐Meunier, Christophe Glorion, Patrick Nusbaum, Christine Bodemer, Guy Mouchiroud, Jamel Chelly, Stéphane Germain, Isabelle Desguerre, Bénédicte C Tags: Original Article Source Type: research
