Blood-cerebrospinal fluid (CSF) barrier dysfunction means reduced CSF flow not barrier leakage - conclusions from CSF protein data
Conclusion: Blood-CSF and blood-brain barrier dysfunctions are an expression of reduced CSF or ISF flow rate.RESUMO Introdu ção: Concentrações aumentadas de proteínas séricas no líquido cefalorraquidiano são interpretadas como disfunção da barreira (hemato-liquórica) sanguínea do LCR. Interpretações frequentemente usadas, como vazamento de barreira (quebra ou rompimento de barreira), rompimento ou quebra, contradiz os dados de proteína do LCR, que sugerem uma taxa de fluxo reduzida do LCR como a causa. Resultados: Mesmo as disfunções de barreira mais graves não alteram a seletividade dependente do ta...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Trigeminal neuralgia recurrence: a comparison of microvascular decompression and percutaneous balloon compression: a five years follow-up study
Conclusions: MD presented with a more precocious recurrence of pain than PBC in this article. Moreover, it had a higher recurrence rate than described in the literature as well, which is possibly explained by the type of graft (muscle) that was used to separate the neurovascular structures.RESUMO Introdu ção: Cerca de 50% dos pacientes com neuralgia do trigêmeo não apresenta benefícios a longo prazo com o uso de medicação oral. Para a manutenção do tratamento, algumas opções cirúrgicas estão disponíveis, sendo a compressão percutânea por balão (CPB) e a descompressão microvascular (DM) algumas das mod...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
The impact of physical functions on depressive symptoms in people with multiple sclerosis
Conclusions: Impairment in physical functions consists in a potential predictor of depressive symptoms in people with MS. Exercise interventions aiming at the improvement of physical functions, together with the treatment of depressive symptoms and conventional medical treatment, are suggested.RESUMO Introdu ção: A esclerose múltipla (EM) é uma doença imunomediada que afeta o sistema nervoso central. O impacto da doença transcende as funções físicas e se estende a comprometimento psicológico. Aproximadamente 50% das pessoas com EM desenvolvem sintomas depressivos e estes podem predizer o comp rometimento das f...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Is restless legs syndrome in Parkinson disease patients associated with any specific factor?
Conclusion: Restless legs syndrome is a prevalent condition in patients with Parkinson disease and is associated with specific characteristics in this group of patients.RESUMO Introdu ção: A síndrome das pernas inquietas, ou doença de Willis-Ekbom, é um transtorno caracterizado por sensações de desconforto associadas à necessidade de movimentar os membros inferiores. Nos pacientes com doença de Parkinson, a síndrome das pernas inquietas está associada a uma qualidade de vida inferior e sonolência excessiva. Em relação a outros fatores, resultados de diferentes estudos mostraram resultados controversos. Ob...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Multimorbidity and associated outcomes among older adult inpatients with neurological disorders
Conclusions: Multimorbidity was preponderant among older adults inpatients with NDs, and NDs had a high degree of associated chronic comorbidities. Multimorbidity, but not isolated NDs, was associated with readmission and long LOS. These results support ward-based, neurohospitalist-directed, interdisciplinary care for older adults inpatients with NDs to face multimorbidity.RESUMO Introdu ção: A multimorbidade é comum entre idosos e está associada a privação socioeconômica, polifarmácia, má qualidade de vida, déficit funcional e mortalidade. Objetivos: Identificar a frequência da multimorbidade entre pacient...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Trends in prescribing patterns of antiepileptic drugs among older adult inpatients in a Brazilian tertiary center
Conclusions: Phenytoin was the main suboptimal AED prescribed in our population, and convulsive SE and acute symptomatic seizures associated with some etiologies were independent risk factors for phenytoin prescription. These results suggest ongoing commitment to reducing the prescription of suboptimal AEDs, particularly phenytoin in Brazilian emergence rooms.RESUMO Introdu ção: Os dados referentes à prescrição de drogas antiepilépticas (DAE) em pacientes idosos hospitalizados são limitados. Objetivo: Avaliar as mudanças no padrão de prescrição de DAE em idosos hospitalizados com epilepsia de início tardio...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Simultaneous electrocardiogram during routine electroencephalogram: arrhythmia rates through the eyes of the cardiologist
Conclusions: A considerably high rate of arrhythmia cases was determined on simultaneous ECG during routine EEG after being interpreted by a cardiologist. However, the screening results of EEG reports revealed relatively low arrhythmia rates. These results suggest that the detection rates of ECG abnormalities during routine EEG may be potentially improved.RESUMO Introdu ção: A importância do registro simultâneo de eletrocardiograma (ECG) de duas derivações durante o eletroencefalograma (EEG) de rotina foi relatada várias vezes por motivos clínicos. Objetivos: Investigar as taxas de arritmias detectadas em ECG de ...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Swallowing in behavioral variant frontotemporal dementia
Conclusion: Patients with bvFTD had inappropriate speed eating, passivity, coughing and choking starting in the mild dementia stage, and these problems worsen in the severe stage. Such difficulties affected caregiver performance during mealtime. The correlations indicated that swallowing difficulties tend to follow cognitive and behavioral decline in patients with bvFTD.RESUMO Introdu ção: Os problemas na situação de alimentação e deglutição podem ocorrer com a progressão da variante comportamental da demência frontotemporal (DFT-vc) e alterar as fases antecipatória e preparatória oral da deglutição. Obje...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Realistic simulation is associated with healthcare professionals’ increased self-perception of confidence in providing acute stroke care: a before-after controlled study
Conclusions: This stroke realistic simulation course was associated with an improvement on trainees ’ self-perception of confidence in providing acute stroke care.RESUMO Introdu ção: Simulações são amplamente utilizadas na educação médica, mas há pouca evidência de sua eficácia no tratamento de pacientes neurocríticos. Como o acidente vascular cerebral agudo (AVC) é uma patologia que requer atendimento imediato, o uso de simulação pode ser uma ferramenta út il no treinamento do manejo desses pacientes. Objetivo: Avaliar o impacto do uso de simulação realística na autopercepção de segurança no ...
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
EEG-EKG, or when 1 + 1 is more than 2
(Source: Arquivos de Neuro-Psiquiatria)
Source: Arquivos de Neuro-Psiquiatria - February 26, 2021 Category: Neurology Source Type: research
Telemedicine in neurology: current evidence
Conclusion: Current evidence supports that teleneurology can be a tool to increase care for patients suffering from neurological diseases.RESUMO Introdu ção: A telemedicina surge pela primeira vez na neurologia como uma ferramenta para facilitar o acesso ao tratamento do acidente vascular cerebral (AVC) Agudo. Mais recentemente, inúmeras evidências têm surgido acerca da eficácia e da segurança do uso da telemedicina em várias outras áreas d a neurologia. Com o advento da pandemia de COVID-19 e a necessidade de isolamento social, as autoridades brasileiras flexibilizaram a regulamentação da telemedicina, permiti...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research
Neuroimaging and ophthalmologic findings in incomplete Susac syndrome
ABSTRACT The authors review the role of Jules Bernard Luys in the discovery of the subthalamic nucleus (STN) over 150 years ago. The relationships between the STN and movement disorders, particularly hemiballismus and Parkinson ’ s disease, are well known. The academic life of Jules Bernard Luys can be divided into two periods: a brilliant start as a neuroanatomist, culminating in the discovery of the STN, followed by a second period marked by a shift in his academic activity and an increased interest in topics such as hysteria, hypnotism and, eventually, esotericism.RESUMO Os autores revisam o papel de Jules Bernard Luy...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research
Acute parkinsonism and bilateral basal ganglia lesions
ABSTRACT The authors review the role of Jules Bernard Luys in the discovery of the subthalamic nucleus (STN) over 150 years ago. The relationships between the STN and movement disorders, particularly hemiballismus and Parkinson ’ s disease, are well known. The academic life of Jules Bernard Luys can be divided into two periods: a brilliant start as a neuroanatomist, culminating in the discovery of the STN, followed by a second period marked by a shift in his academic activity and an increased interest in topics such as hysteria, hypnotism and, eventually, esotericism.RESUMO Os autores revisam o papel de Jules Bernard Luy...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research
Malignant cerebral edema: an unusual neurological manifestation of systemic lupus erythematosus
ABSTRACT The authors review the role of Jules Bernard Luys in the discovery of the subthalamic nucleus (STN) over 150 years ago. The relationships between the STN and movement disorders, particularly hemiballismus and Parkinson ’ s disease, are well known. The academic life of Jules Bernard Luys can be divided into two periods: a brilliant start as a neuroanatomist, culminating in the discovery of the STN, followed by a second period marked by a shift in his academic activity and an increased interest in topics such as hysteria, hypnotism and, eventually, esotericism.RESUMO Os autores revisam o papel de Jules Bernard Luy...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research
Jules Bernard Luys: from a description of the subthalamic nucleus to hypnotism
ABSTRACT The authors review the role of Jules Bernard Luys in the discovery of the subthalamic nucleus (STN) over 150 years ago. The relationships between the STN and movement disorders, particularly hemiballismus and Parkinson ’ s disease, are well known. The academic life of Jules Bernard Luys can be divided into two periods: a brilliant start as a neuroanatomist, culminating in the discovery of the STN, followed by a second period marked by a shift in his academic activity and an increased interest in topics such as hysteria, hypnotism and, eventually, esotericism.RESUMO Os autores revisam o papel de Jules Bernard Luy...
Source: Arquivos de Neuro-Psiquiatria - December 14, 2020 Category: Neurology Source Type: research
