Migraine in 746 patients with multiple sclerosis
Conclusion: Migraine is a frequent and disabling type of primary headache reported by patients with MS.RESUMO Enxaqueca piora o sofrimento do paciente que tem esclerose m últipla (EM). ID-migraine é uma ferramenta útil para seleção de pacientes com enxaqueca e Migraine Disability Assessment (MIDAS) é um questionário que avalia o impacto da doença. O objetivo do presente estudo foi avaliar a presença e impacto de enxaqueca em pacientes com EM. Métodos: Paci entes diagnosticados com EM e tratados em clínicas especializadas foram convidados a responder um questionário online se também apresentassem cefaleia. Re...
Source: Arquivos de Neuro-Psiquiatria - September 23, 2019 Category: Neurology Source Type: research
Obstructive sleep apnea and Parkinson's disease: characteristics and associated factors
Conclusion: The PD patients showed a high prevalence of OSA, with the supine position exerting a significant influence on the OSA in these patients, and some factors that are associated with OSA in the general population did not seem to have a greater impact on PD patients.RESUMO A Apneia Obstrutiva do Sono (AOS) chega a acometer at é 66% dos pacientes com doença de Parkinson (DP), prevalência maior, portanto, que a da população geral. Embora seja mais prevalente, a relação entre AOS e DP permanence controversa, com trabalhos confirmando e outros afastando a relação de AOS com alguns fatores de risco e sintomas em...
Source: Arquivos de Neuro-Psiquiatria - September 23, 2019 Category: Neurology Source Type: research
Memory impairments and increased GFAP expression in hippocampal astrocytes following hypercaloric diet in rats
Conclusion: This astrogliosis suggests that the neuroinflammatory response also occurs in the hippocampus and may be involved in the memory losses observed in obese/overweight animals.RESUMO Objetivo: A inflama ção hipotalâmica e a superexpressão da proteína glial fibrilar ácida (GFAP) em astrócitos são bem descritas em animais obesos, assim como déficits cognitivos e de memória. Como o hipocampo desempenha importante papel na consolidação de informações, esta investigação teve como objetiv o observar a função da memória e a expressão astrocitária da GFAP no hipocampo de ratos que receberam dieta hipe...
Source: Arquivos de Neuro-Psiquiatria - September 23, 2019 Category: Neurology Source Type: research
Recognizing migraine in patients with multiple sclerosis improves the quality of health care
(Source: Arquivos de Neuro-Psiquiatria)
Source: Arquivos de Neuro-Psiquiatria - September 23, 2019 Category: Neurology Source Type: research
Reply
ABSTRACT Jean-Martin Charcot (1825-1893), considered the father of modern neurology, had a particular interest in pathology and learned to value anatomical findings. Among his main contributions is the use of the anatomo-clinical method in neurology. Although described as cold and impatient in his interpersonal relations, Charcot had a great affection for animals. He had two dogs in his home, which he called Carlo and Sigurd, and a little monkey, Rosalie. Despite his fascination with neuropathology and anatomo-clinical correlations, Charcot disapproved of studies using animal species other than humans, a seemingly paradoxi...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Genetic work-up of hereditary spastic paraplegias is crucial for classifying these disorders
ABSTRACT Jean-Martin Charcot (1825-1893), considered the father of modern neurology, had a particular interest in pathology and learned to value anatomical findings. Among his main contributions is the use of the anatomo-clinical method in neurology. Although described as cold and impatient in his interpersonal relations, Charcot had a great affection for animals. He had two dogs in his home, which he called Carlo and Sigurd, and a little monkey, Rosalie. Despite his fascination with neuropathology and anatomo-clinical correlations, Charcot disapproved of studies using animal species other than humans, a seemingly paradoxi...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Dural metastasis of prostate adenocarcinoma with spontaneous subdural hematoma: an unusual mimicker of meningioma
ABSTRACT Jean-Martin Charcot (1825-1893), considered the father of modern neurology, had a particular interest in pathology and learned to value anatomical findings. Among his main contributions is the use of the anatomo-clinical method in neurology. Although described as cold and impatient in his interpersonal relations, Charcot had a great affection for animals. He had two dogs in his home, which he called Carlo and Sigurd, and a little monkey, Rosalie. Despite his fascination with neuropathology and anatomo-clinical correlations, Charcot disapproved of studies using animal species other than humans, a seemingly paradoxi...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Magnetic resonance imaging traits may help to differentiate Pelizaeus-Merzbacher and Pelizaeus-Merzbacher-like disease
ABSTRACT Jean-Martin Charcot (1825-1893), considered the father of modern neurology, had a particular interest in pathology and learned to value anatomical findings. Among his main contributions is the use of the anatomo-clinical method in neurology. Although described as cold and impatient in his interpersonal relations, Charcot had a great affection for animals. He had two dogs in his home, which he called Carlo and Sigurd, and a little monkey, Rosalie. Despite his fascination with neuropathology and anatomo-clinical correlations, Charcot disapproved of studies using animal species other than humans, a seemingly paradoxi...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Charcot's paradox
ABSTRACT Jean-Martin Charcot (1825-1893), considered the father of modern neurology, had a particular interest in pathology and learned to value anatomical findings. Among his main contributions is the use of the anatomo-clinical method in neurology. Although described as cold and impatient in his interpersonal relations, Charcot had a great affection for animals. He had two dogs in his home, which he called Carlo and Sigurd, and a little monkey, Rosalie. Despite his fascination with neuropathology and anatomo-clinical correlations, Charcot disapproved of studies using animal species other than humans, a seemingly paradoxi...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Duchenne muscular dystrophy: an historical treatment review
ABSTRACT In this review, we discuss the therapies used in the treatment of patients with Duchenne muscular dystrophy since the first description of the disease. A short description is given of the various theories based on disease pathogenesis, which give the substrates for the many therapeutic interventions. A brief review of the methods of evaluation used in therapeutic trials is made. Of all the treatments, the only drugs that are still considered able to modify the course of the disease are the corticosteroids (prednisone/prednisolone/deflazacort). Other drugs (coenzyme Q10 and creatine) have had a little effect in a f...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Theory of mind impairment in Huntington's disease patients and their relatives
Conclusion: The HD patients with mild to moderate disease severity and their relatives show ToM deficits.RESUMEN La enfermedad de Huntington (EH) es una enfermedad gen ética autosómica dominante caracterizada por trastornos del movimiento, deterioro cognitivo y síntomas psiquiátricos. Los familiares de las personas con EH experimentan gran carga dado que los pacientes sufren de conducta social alterada y deterioro de relaciones interpersonales. La Teoría de l a mente (ToM) consiste en la habilidad para atribuir estados mentales (a uno mismo o a otros). Se piensa que déficits en ToM tienen un rol en los cambios en emp...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Can the positions of the spastic upper limb in stroke survivors help muscle choice for botulinum toxin injections?
Conclusion: Frequencies of upper-limb postures differed from previous reports. Other clinical features, besides spasticity, interfered with muscle choice for BoNT-A injection, which only partially followed the recommendations in the literature.RESUMO As defici ências motoras que ocorrem nos indivíduos com doença cerebrovascular (DCV) são prevalentes e contribuem para dependência, dor e incapacidade, o que pode atrasar a reabilitação do membro superior e sua funcionalidade. O tratamento com toxina botulínica do tipo A (BoNT-A) é indicado para a es pasticidade focal e requer conhecimento da biomecánica e anatomia p...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Development of a word accentuation test for predicting cognitive performance in Portuguese-speaking populations
Conclusion: A version of the WAT for Portuguese-speaking populations was developed and proved to be a valuable tool for estimating cognitive performance.RESUMO O Teste de Acentua ção de Palavras (TAP) tem sido utilizado para predizer inteligência pré-mórbida e desempenho cognitivo em populações de língua espanhola. Requer que os sujeitos leiam uma lista de palavras sem os sinais gráficos de acentuação que indicam a sílaba tônica. Objetivo: Como a pronúncia da língua portuguesa também é fortemente baseada em acentos gráficos, nosso objetivo foi desenvolver uma versão brasileira do TAP. Métodos: Um conj...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Environmental enrichment reduces brain excitability in adult rats overnourished during lactation
Conclusion: Our data demonstrated that EE exposure in the juvenile phase of the rat's life reduced brain excitability, and this effect was observed even if animals were overnourished during lactation. An EE could be considered an adjuvant therapeutic resource to modulate brain excitability.RESUMO Objetivo: Este estudo analisou se a exposi ção ao ambiente enriquecido durante a fase juvenil da vida interferiria na atividade elétrica do cérebro de ratos adultos. Além disso, a presente pesquisa também investigou se esse provável efeito na atividade elétrica cerebral poderia ser afetado pela hipernutrição durante a l...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
Diaphragm quantitative electromyography in difficult-to-treat asthmatic patients
In this report, diaphragm quantitative electromyography was used to evaluate asthmatic difficult-to-treat patients, comparing them with a control group. Significant differences were obtained in amplitude, duration and size index of motor unit action potentials, with lower parameters in the asthmatic patients, which may indicate a myopathic process.RESUMO Eletromiografia quantitativa é uma ferramenta importante para a avaliação de miopatias, e alguns pacientes asmáticos de difícil controle podem ter um processo miopático subclínico, mesmo usando apenas corticosteroides inalatórios, de acordo com alguns artigos. Ness...
Source: Arquivos de Neuro-Psiquiatria - September 6, 2019 Category: Neurology Source Type: research
