Association between endoscopic findings and histopathological confirmation in patients with suspicion of eosinophilic esophagitis
CONCLUSION: There was a low association between the presence of endoscopic findings and histopathological confirmation of the disease, which indicates that endoscopic findings alone are not reliable for the diagnosis of EoE.RESUMO CONTEXTO: O diagn óstico da esofagite eosinofílica é realizado através da detecção, em amostra de biópsia esofágica, de 15 ou mais eosinófilos por campo, sendo que os achados endoscópicos isolados não são validados para o diagnóstico da doença. OBJETIVO: Avaliar a associação entre os achados endoscó picos com o diagnóstico histopatológico em pacientes com suspeita de esofa...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Hla-drb1 gene polymorphisms in pediatric patients with type 1 autoimmune hepatitis and type 1 autoimmune hepatitis overlap syndrome with autoimmune cholangitis
CONCLUSION: This work demonstrates an association of the main polymorphisms in the HLA-DRB1 gene to AIH with or without cholangitis in a Brazilian sample.RESUMO CONTEXTO: Hepatite autoimune (HAI) é uma doença hepática inflamatória crônica, rara, associada à perda da tolerância imunológica aos auto-antígenos. A susceptibilidade à HAI é parcialmente determinada pela presença de genes relacionados ao antígeno leucocitário humano (HLA), principalmente variantes alélicas do DRB1. OBJETIVO: O objetivo deste estudo foi investigar a frequência de polimorfismos no gene HLA-DRB1 em crianças e adolescentes com HA...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Investigation of enterococcus faecalis population in patients with polyp and colorectal cancer in comparison of healthy individuals
CONCLUSION: Enterococcus faecalis in faecal flora of people with colorectal cancer was significantly higher than those with polyps and healthy people. This could potentially signify the ability of this bacterium to induce colorectal cancer. More studies are needed to prove this theory.RESUMO CONTEXTO: O c âncer colorretal é um dos cânceres mais comumente diagnosticados em todo o mundo. Um dos fatores envolvidos no desenvolvimento do câncer colorretal é a mudança na flora normal do intestino. OBJETIVO: O número médio de cópias de Enterococcus faecalis em pessoas com pólipos e pessoas com c âncer colorretal fo...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Relationship among psychological well-being, resilience and coping with social and clinical features in crohn’s disease patients
CONCLUSION: Social aspects influenced psychological well-being, resilience and Coping in patients with Crohn ’ s disease more strongly than clinical aspects. It was possible to identify the profiles with better and worse psychological well-being, resilience and Coping of those who need more support, as well as to know the most used Coping strategies in the studied group.RESUMO CONTEXTO: A doen ça de Crohn é crônica, exige tratamento prolongado e afeta a saúde física e psicossocial dos pacientes podendo alterar sua rotina, qualidade de vida e bem-estar. Estudo recentes recomendam a monitoração da saúde destes p...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Immunization status of patients with inflammatory bowel disease
CONCLUSION: Although being a specialized service linked to a university hospital, vaccination coverage and patients ’ awareness rates proved to be below the desirable level. Vaccination and recovery of the immunization history is recommended immediately after the diagnosis of IBD, regardless of the use of biological agents. Those findings support the need of implementing hospital guidelines and constantly verifying its application by the multidisciplinary team in specialized services in IBD.RESUMO CONTEXTO: No tratamento de doen ças inflamatórias intestinais (DII) são usados imunossupressores e agentes biológicos...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Are cariogenic bacteria the major risk factor to dental caries in patients with ulcerative colitis?
CONCLUSION: The prevalence of dental caries observed in UC patients was significant and did not seem to be influenced by their eating habits. The high prevalence of Mutans streptococci count may be a major risk factor for dental caries and may be looked as part of the UC dysbiosis. Dental care of UC patients should be planned according with this microbiota variation.RESUMO CONTEXTO: Uma elevada preval ência de cáries dentárias em doentes com retocolite ulcerativa (RCU) tem sido atribuída à dieta e alterações no ambiente salivar. OBJETIVO: Este estudo pretende caracterizar a prevalência de cáries dentárias, t...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Does the rheumatoid arthritis affect the enteric nervous system?
CONCLUSION: Despite arthritis resulted in no alterations in the number of nitrergic neurons, the retraction of ileal area and reduction of nitrergic somatic and VIP-IR varicosity areas may suggest a negative impact the disease on the ENS.RESUMO CONTEXTO: Poucos estudos sobre doen ças artríticas têm sido realizados para verificar a presença de neurodegeneração. Diante do aumento do estresse oxidativo e dos efeitos extra-articulares da artrite reumatoide, estudos gastrointestinais devem ser investigados visando uma melhor compreensão dos efeitos sistêmicos da doença n o sistema nervoso entérico. OBJETIVO: Dete...
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Psychological well-being and quality of life in the clinical approach in crohn’s disease
(Source: Arquivos de Gastroenterologia)
Source: Arquivos de Gastroenterologia - August 27, 2019 Category: Gastroenterology Source Type: research

Partial retraction
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warran...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Letter to editor about “new index for the diagnosis of liver fibrosis in schistosomiasis mansoni”
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warran...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

35 years of the classification of rezende: the importance of esophagogram in the context of chagas disease in brazil
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warran...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Safety and efficacy of eus-guided coil plus cyanoacrylate versus conventional cyanoacrylate technique in the treatment of gastric varices: a randomized controlled trial
CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warran...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Treating simple benign esophageal strictures with savary-gilliard dilators: is the rule of three still necessary?
CONCLUSION: The rule of three in patients with simple benign esophageal strictures secondary to esophageal webs, Schatzki rings and peptic strictures treated with Savary-Gilliard dilators is not necessary, showing good clinical results. Prospective studies with more patients are necessary.RESUMO CONTEXTO: A dilata ção por velas é considerada uma técnica eficaz para o tratamento de estenoses esofágicas benignas simples. A “ regra de tr ês ” tem sido defendida para prevenir eventos adversos relatados, como sangramento e perfura ção. No entanto, a adesão a esta regra aumentou o custo e a duração do tratamen...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

ASSOCIATION OF TNF- α-308G>A POLYMORPHISM WITH SUSCEPTIBILITY TO CELIAC DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
CONCLUSION: Our meta-analysis suggests that the TNF- α -308G>A polymorphism plays an important role in celiac disease susceptibility. However, our results are still needed to strengthen by further studies in different ethnicities and larger sample sizes.RESUMO CONTEXTO: H á evidências crescentes para mostrar que o TNF- α -308G>A polimorfismo pode ser um fator de risco para a doen ça celíaca, mas os resultados são inconsistentes. OBJETIVO: Por isto objetivou-se realizar uma meta-análise envolvendo estudos publicados até janeiro de 2019 para elucidar esta associação. MÉTODOS: Para avaliar o efeito d...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research

Ultrasonography in determining the rectal diameter and rectal wall thickness in children with and without constipation: a case-control study
CONCLUSION: Transabdominal rectal diameter measurement may be useful in the diagnosis of constipation.RESUMO CONTEXTO: A ultrassonografia tem sido demonstrada como útil no diagnóstico de constipação. OBJETIVO: O objetivo deste estudo foi comparar o diâmetro retal e a espessura da parede retal em crianças com e sem constipação. MÉTODOS: Foram incluídas no estudo crianças com diagnóstico de constipação de acordo com os critérios de Roma III. A s crianças foram submetidas à ultrassonografia abdominal com bexiga cheia para avaliação do diâmetro retal e da espessura da parede retal. Crianças sem cons...
Source: Arquivos de Gastroenterologia - May 23, 2019 Category: Gastroenterology Source Type: research