Mechanisms and biomarker candidates in pterygium development
ABSTRACT To identify and classify available information regarding COVID-19 and eye care according to the level of evidence, within four main topics of interest: evidence of the virus in tears and the ocular surface, infection via the conjunctival route, ocular manifestations, and best practice recommendations. A structured review was conducted in PubMed, ScienceDirect, LILACS, SciELO, the Cochrane Library and Google Scholar on COVID-19 and ophthalmology. The Oxford Centre for Evidence Based Medicine 2011 Levels of Evidence worksheet was used for quality assessments. 1018 items were identified in the search; 26 records were...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

COVID-19 and the eye: how much do we really know? A best evidence review
ABSTRACT To identify and classify available information regarding COVID-19 and eye care according to the level of evidence, within four main topics of interest: evidence of the virus in tears and the ocular surface, infection via the conjunctival route, ocular manifestations, and best practice recommendations. A structured review was conducted in PubMed, ScienceDirect, LILACS, SciELO, the Cochrane Library and Google Scholar on COVID-19 and ophthalmology. The Oxford Centre for Evidence Based Medicine 2011 Levels of Evidence worksheet was used for quality assessments. 1018 items were identified in the search; 26 records were...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Unintentional injection of a dexamethasone implant into the crystalline lens: a case report
ABSTRACT The intravitreal dexamethasone implant is a sustained-release anti-inflammatory drug system that releases 0.7 mg of dexamethasone into the vitreous cavity. The following case report describes a rare complication: accidental injection of the dexamethasone implant into the crystalline lens. A 73-year-old woman was diagnosed with central retina vein occlusion and cystoid macular edema. Initial tSreatment included three monthly intravitreal doses of anti-vascular endothelial growth factor treatment, which was not successful. Treatment was then modified to an intravitreal dexamethasone implant. Ten weeks later, the imp...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Dexamethasone intravitreal implant in the crystalline lens: a case report
This report describes the therapeutic effects and outcomes of an accidental injection of an intralenticular sustained-release dexamethasone implant (Ozurdex ®) in three patients with diabetic macular edema. All three patients underwent accidental injections of sustained-release intravitreal dexamethasone implants into the crystalline lens by the same surgeon. After the accidental injection of Ozurdex® into the crystalline lens, a remarkable reduction in the macular edema and an improvement in visual acuity were observed, suggesting that a positive outcome can be achieved without immediate surgery.RESUMO Este estudo descr...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Ophthalmologic alterations in cutis marmorata telangiectatica congenita: a series of cases
We describe ophthalmologic alterations found in three patients with cutis marmorata telangiectatica congenita highlighting the rare retinal manifestations.RESUMO A Cutis marmorata telangiectasica cong ênita é uma desordem vascular cutânea rara que pode estar associada a diferentes manifestações sistêmicas, como assimetria corporal, alterações cutâneas, oftalmológicas, vasculares e neurológicas. Descrevemos alterações oftalmológicas encontradas em três pacientes com cutis marmorata telangiectasia congênita, destacando as raras manifestações retinianas. (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Double puncta canaliculi may exhibit different clinical presentations
This report was written to emphasize that unilateral epiphora of dry eye symptoms may be related to supernumerary punctum or canalicular systems and can easily be diagnosed with lid eversion.RESUMO Neste artigo, descrevemos dois pacientes adultos que apresentaram pun ção lacrimal dupla: um deles assintomático e diagnosticado incidentalmente, e o outro queixava-se de epífora. Nos dois pacientes, unilateralidade, preferência pela pálpebra inferior e posição medial pelo ponto normal foram características comuns do ponto acessório. No paciente assintomáti co, a irrigação não revelou obstrução no ponto ou no sis...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Topical mitomycin in endoscopic-assisted probing for the treatment of congenital nasolacrimal duct obstruction in older children
Conclusions: Although mitomycin C has no adverse effects when applied to the opening of the nasolacrimal duct, its use after lacrimal probing for the treatment of congenital nasolacrimal duct obstruction does not improve the chance of success.RESUMO Objetivo: A mitomicina C tem sido usada em cirurgia oft álmica para reduzir cicatrizes pós-operatórias. Entretanto, os resultados da sondagem endoscópica assistida para o tratamento da obstrução congênita do ducto nasolacrimal com mitomicina C adjuvante em crianças permanecem desconhecidos. Nosso estudo teve como objetivo avaliar a eficácia e a segurança da aplicaÃ...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Does wearing swimming goggles affect corneal morphology in keratoconic eyes?
Conclusions: These findings suggested that the short-term use of swimming goggles does not increase the risk of corneal parameter worsening in patients with keratoconus.RESUMO Objetivo: Um aumento transit ório significativo da pressão intraocular em indivíduos usando óculos de natação foi demonstrado em estudos anteriores. Esses achados sugerem que o uso de óculos de natação pode representar um fator de risco significativo para o agravamento dos parâmetros corneanos em pacientes com ceratoc one que nadam regularmente. O objetivo deste estudo foi investigar os parâmetros corneanos em pacientes com ceratocone apÃ...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Baerveldt implant versus trabeculectomy as the first filtering surgery for uncontrolled primary congenital glaucoma: a randomized clinical trial
Conclusions: Both the tube and trabeculectomy groups presented similar intraocular pressure controls, but complete success was more frequent in the trabeculectomy grou p. Non-valved glaucoma drainage devices caused potentially blinding complications during tube opening. Because of the small sample size, we could not draw conclusions as to the safety data of the studied technique.RESUMO Objetivo: O objetivo inicial era comparar a efic ácia e a segurança do implante de drenagem e a trabeculectomia em crianças com glaucoma congênito primário após falência de cirurgia angular. Como o estudo foi descontinuado devido à ...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Costs and outcomes of phacoemulsification for cataracts performed by residents
Conclusion: These data indicate that cataract surgery performed by in-training ophthalmologists using phacoemulsification is expensive, but compared to extracapsular cataract extraction results, teaching phacoemulsification leads to an approximate three-fold lower complication rate, smaller number of postoperative visits and, most importantly, better visual acuities.RESUMO Objetivo: Descrever os custos e resultados da facoemulsifica ção na cirurgia de catarata realizada por médicos residentes de oftalmologia. Métodos: Foram obtidos prontuários médicos de pacientes operados em 2011 por residentes do terceiro ano (R3...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Infrared thermography for the analysis of ocular surface temperature after phacoemulsification
Conclusions: The reduction in ocular surface temperature toward the end of post-cataract surgery follow-up may be associated with increased instability of the tear film after phacoemulsification. Therefore, patient awareness regarding the possibility of clinical symptoms of dry eye syndrome during the first month after surgery should be part of clinical manageme nt of cataract surgery. Ocular surface temperature did not increase after cataract surgery, suggesting the absence of significant inflammation, and the temperature about 1 month after cataract surgery was comparable to that before surgery. Nevertheless, the negativ...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Mapping the corneal thickness and volume in patients with Down syndrome: a comparative population-based study
Conclusion: Non-keratoconic patients with Down syndrome had thin corneas with a homogeneous distribution. Therefore, the reference ranges of cornea thickness and volume should be re-defined for this patient population.RESUMO Objetivo: Medir a espessura corneana central e perif érica e se4u volume de acordo com a idade e gênero em pacientes com idades entre 10 e 30 anos com síndrome de Down e em indivíduos saudáveis sem síndrome de Down. Métodos: No estudo 202 olhos normais direitos de pacientes com síndrome de Down e 190 olhos direitos de indivíduos sem síndrom e de Down e médias comparadas usando o teste t de...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Dynamic changes of periostin and collagen I in the sclera during progressive myopia in guinea pigs
Conclusions: Periostin was expressed in the myopic sclera of guinea pigs, and changes in periostin and collagen I expression were highly consistent. Periostin and collagen I may be involved in the regulation of scleral remodeling in myopia.RESUMO Objetivo: Investigar a express ão da periostina e do colágeno I durante o remodelamento escleral em olhos míopes e determinar seu papel na remodelação do colágeno da esclera miópica. Métodos: Cinquenta cobaias com uma semana de idade foram divididas em grupo controle e miopia de privação de forma. Os olhos dos animais no grupo de miopia de privação de forma foram cob...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Long-term comparison of the efficacies of internal and external browpexy combined with blepharoplasty
Conclusions: External and internal browpexy surgery afforded adequate and similar elevations of the central and lateral brow, which were significantly different from those in the standard blepharoplasty group during long-term follow-up.RESUMO Objetivo: Avaliar a compara ção, a longo prazo, da eficácia quantitativa da sobrancelha interna e externa em combinação com a blefaroplastia da pálpebra superior com base nas posições lateral e central da sobrancelha. Métodos: Este estudo retrospectivo avaliou as cirurgias interna e externa da braquiterapia com blef aroplastia de pálpebra superior realizadas entre janeiro...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research

Bupivacaine injection for comitant horizontal strabismus: clinical and radiological results
Conclusions: Bupivacaine injection improved eye alignment in small-angle horizontal comitant strabismus, effectively diagnosed with orbital magnetic resonance imaging to evaluate volumetric changes of the extraocular muscles. Further clinical studies with larger numbers of patients should be performed to define optimal dosages, concentration, and application method and dose-response relationship.RESUMO Objetivo: Relatar resultados da inje ção de bupivacaína para o tratamento do estrabismo comitante horizontal e avaliar sua eficácia clínica e as alterações radiológicas associadas. Métodos: Este estudo clínico ob...
Source: Arquivos Brasileiros de Oftalmologia - May 29, 2020 Category: Opthalmology Source Type: research