Largest case series of Latin American eyelid tumors over 13-Years from a single center in Sao Paulo, Brazil
Conclusion: This is the largest retrospective cohort analysis of eyelid tumors in a Latin American population. These findings are in agreement with those from large centers in other countries and regions.RESUMO Objetivo: As les ões malignas de pálpebras são os cânceres oftalmológicos mais frequentes. Embora raramente letal, o diagnóstico tardio pode levar a diversas complicações severas e a uma alta taxa de morbidade visual. O diagnóstico definitivo de lesões neoplásicas é patológico. No presente estudo, revis amos casos de um ú...
Source: Arquivos Brasileiros de Oftalmologia - March 12, 2018 Category: Opthalmology Source Type: research

Normative values for optical coherence tomography parameters in healthy children and interexaminer agreement for choroidal thickness measurements
ABSTRACT Purpose: To (a) determine the normative values for optical coherence tomography (OCT) parameters such as central macular thickness, retinal nerve fiber layer thickness, and choroidal thickness in healthy children; (b) investigate the relationships of these parameters with axial length, central corneal thickness, refractive errors, and intraocular pressure; and (c) determine interexaminer agreement for choroidal thickness measurements. Methods: In this cross-sectional study, 120 healthy children aged 8-15 years underwent detailed ophthalmological examination and OCT measurements. Choroidal thickness was measured at...
Source: Arquivos Brasileiros de Oftalmologia - March 12, 2018 Category: Opthalmology Source Type: research

80 years of Arquivos Brasileiros de Oftalmologia (ABO)
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - March 12, 2018 Category: Opthalmology Source Type: research

ABO: 80th anniversary
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - March 12, 2018 Category: Opthalmology Source Type: research

Optimizing literature search in systematic reviews: is MEDLINE sufficient for identifying effect studies on corneal properties and glaucoma?
ABSTRACT Information and communication technology has rapidly reached diverse aspects of modern life, including medicine and health-related matters. Aiming to improve teaching, research, and health care delivery for geographic or economic reasons, telemedicine is an ascending trend. Teleophthalmology might be one of the most challenging applications of telemedicine given its need for standardized and high definition digital images. However, technological advances are enhancing information transmission continuously and expanding the potential of teleophthalmology. In this review, we investigate the evolution and current sta...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Teleophthalmology: where are we now?
ABSTRACT Information and communication technology has rapidly reached diverse aspects of modern life, including medicine and health-related matters. Aiming to improve teaching, research, and health care delivery for geographic or economic reasons, telemedicine is an ascending trend. Teleophthalmology might be one of the most challenging applications of telemedicine given its need for standardized and high definition digital images. However, technological advances are enhancing information transmission continuously and expanding the potential of teleophthalmology. In this review, we investigate the evolution and current sta...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Conjunctival tattoo: report on an emerging body modification trend
We report the case of a patient who received conjunctival tattooing for cosmetic purposes with associated complications. A 28-year-old male experienced severe ocular pain after undergoing conjunctival tattooing. Slit-lamp examination revealed blue deposits over the conjunctiva in association with intense conjunctival edema and a 4+ anterior chamber cellular reaction. The patient underwent clinical treatments to control ocular inflammation. Two months after the injury, the patient was still in follow-up to ensure that any further complications were managed and documented. This unusual case of conjunctival tattooing resulted...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

An unusual presentation of ocular rosacea
ABSTRACT Rosacea is a chronic, progressive disease of unknown cause affecting the eye and the facial skin. Ocular rosacea is often underdiagnosed if the ophthalmologist does not inspect the patient ’ s face adequately during the ocular examination. Severe ocular complications and blindness can occur if the treatment is delayed because of non-diagnosis of the rosacea. Here, we present a case of ocular rosacea in a 78-year-old Caucasian woman. Based on the ocular lesions, which preceded cutaneous involvement, she was misdiagnosed as having ocular cicatricial pemphigoid initially. This case emphasizes the difficulty in ...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Trocar-assisted intrascleral sutureless fixation of a dislocated three-piece sulcus intraocular lens
ABSTRACT Trocar-assisted intraocular lens (IOL) reposition surgery using a scleral fixation method was performed for a patient with a dislocated sulcus IOL. Two 3-mm-long scleral tunnels 2 mm from and parallel to the limbus were formed using a 23-gauge vitrectomy trocar transconjunctivally entering the sclera at an angle of approximately 10 °. Haptics were collected using a 23-gauge serrated retinal forceps entering from the trocar cannula and externalized from the scleral tunnels together with the trocar. The same procedure was applied for the other haptic. Both haptics were pushed into the scleral tunnel and a transc...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Evolution of optic nerve and retina alterations in a child with indirect traumatic neuropathy as assessed by optical coherence tomography
ABSTRACT Herein, we describe the case of a 4-year-old child with indirect traumatic optic neuropathy and serial changes of the optic nerve head and retinal nerve fiber layer (RNFL) documented using optical coherence tomography (OCT). Visual acuity improved despite progressive RNFL thinning and optic disc pallor. We concluded that OCT may be useful for monitoring axonal loss but may not predict the final visual outcome.RESUMO Descri ção do caso de uma criança de 4 anos de idade com neuropatia óptica traumática indireta, cujas alterações no nervo óptico e na camada de f...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Comparison of linear measurements of optic cup-to-disk ratio obtained with RTVue OCT and digital retinography
ABSTRACT Purpose: To compare the linear measurements of the optic disk cup obtained using RTVue optical coherence tomography (OCT) with those obtained using digital retinography. Methods: This is a cross-sectional study performed with digital retinography and RTVue OCT images from patients with glaucoma or patients suspected of glaucoma. In color retinography, the greatest horizontal and vertical diameters of the optic disk starting from the inner edge of the Elschnig ring were obtained using a pachymeter with a grade of 0.01 mm. In OCT, the delineation of the optic nerve was obtained automatically from the horizontal and ...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

An innovation in glaucoma surgery: XEN45 gel stent implantation
ABSTRACT Purpose: To report follow-up data for patients who underwent XEN45 gel stent implantation, a new method of minimally invasive glaucoma surgery. Methods: Fifteen eyes in fifteen patients who underwent XEN45 gel stent implantation surgery were investigated in the study. All patients were examined preoperatively and at the following postoperative time points: 1 day; 1 and 2 weeks; and 1, 2, 3, 6, and 12 months. Intraocular pressure (IOP) was measured via Goldmann applanation tonometry. Combined surgical procedures (XEN45 + phacoemulsification + intraocular lens) were performed in patients who that had cataracts in ad...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Repeatability and reproducibility of automatic segmentation of retinal layers in healthy subjects using Spectralis optical coherence tomography
Conclusion: It is possible to obtain cross-sections from the same location using the device ’ s follow-up mode, making it virtually impossible to distinguish between repeated measurements taken with the device by different examiners.RESUMO Objetivo: Avaliar a repetibilidade e a reprodutibilidade da segmenta ção automática com tomografia de coerência óptica Spectralis em indivíduos saudáveis. Métodos: Foram incluídos neste estudo prospectivo um total de 60 olhos de 60 pacientes. As imagens de tomografia de coerência óptica de domínio esp...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

A comparison of two conjunctival rotation autograft techniques in primary pterygium surgery
Conclusion: BothCRA techniques can be successful in patients for whom it is desirable to avoid a conjunctival autograft and for patients without high cosmetic expectations.RESUMO Objetivo: Comparar os efeitos das t écnicas de auto-enxerto rotacional de conjuntiva (CRA) de 90° e 180°, usadas na cirurgia de pterígio primário. Métodos: Quarenta e cinco pacientes foram incluídos neste estudo retrospectivo. Acuidade visual (AV) pré e pós-operatória, topografia da córnea, auto-refratometria e exames biom icroscópicos detalhados foram feitos. Durante a ...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Algorithm for dry eye disease diagnosis in individuals infected with human T-cell lymphotropic virus type 1
Conclusion: This study shows the need to use multiple tests to evaluate tear film quality and include a symptom questionnaire as part of the diagnostic algorithm for dry eye disease.RESUMO Objetivo: Avaliar a precis ão da propedêutica do filme lacrimal e propor um algoritmo para o diagnóstico da doença do olho seco em indivíduos infectados com Vírus linfotrópico de células-T humanas tipo 1. Métodos: Noventa e seis pacientes infectados com o vírus linfotrópico de células T humana tipo 1 foram incluí dos no estudo. Para avaliar sintomat...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

In vivo OCT assessment of anterior segment central axial lengths with accommodation
ABSTRACT Purpose: To assess changes in anatomic structures in the anterior eye segment in terms of axial lengths with accommodation via optical coherence tomography. Methods: In this observational study, 25 eyes of 25 healthy adults were examined using the Visante ® omni optical coherence tomography system. Central corneal thickness, anterior chamber depth, central lens thickness, and anterior segment length were assessed. The evaluated parameters were obtained with accommodation using different stimulus vergences, namely 0.0, -1.0, -2.0, and -3.0 D. Variati on of these parameters was compared among different levels of...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Refractive errors in children and adolescents in Bucaramanga (Colombia)
Conclusions: The frequency of refractive errors that we found of 36.7% is moderate compared to the global data. The rates and parameters statistically differed by sex and age groups. Our findings are useful for establishing refractive error rate benchmarks in low-middle-income countries and as a baseline for following their variation by sociodemographic factors.RESUMO Objetivo: O objetivo deste estudo foi estabelecer a frequ ência de erros refrativos em crianças e adolescentes com idade entre 8 e 17 anos, residentes na região metropolitana de Bucaramanga (Colômbia). Métodos: Este estudo foi...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Intermittent exotropia surgery: results in different age groups
ABSTRACT Purpose: To report the outcomes in patients undergoing surgical correction of intermittent exotropia and to compare the age at surgery to motor and sensory success. Methods: This was a retrospective cohort study. The results of patients with intermittent exotropia treated with surgery over a 4-year period were reviewed. Patients were divided into two groups based on age at first surgery (
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Quality of the ophthalmological service to outpatients of the public and private healthcare systems
Conclusions: Institutions must plan, execute, evaluate, and monitor measures that seek to improve the overall patient satisfaction with the quality of services provided, particularly in the private healthcare system, and special attention must be paid to reliability in both healthcare systems. The identification and monitoring of the quality of healthcare services through the periodic use of the SERVQUAL scale may provide healthcare managers with information so that they can identify, plan, and monitor necessary and priority measures. This could be a key strategy for improving the quality of outpatient health services in t...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Tarsal platform show after upper eyelid blepharoplasty with or without brassiere sutures
Conclusions: Brassiere sutures during upper blepharoplasty and traditional blepharoplasty were associated with postoperative increase in TPS, decrease in BFS, and increase in TPS/BFS, without statistically significant differences between these surgeries.RESUMO Objetivo: O aumento do TPS (por ção pretarsal visível) e a diminuição do BFS (porção preseptal visível) estão associados com resultados favoráveis em mulheres submetidas a blefaroplastia estética. Os autores avaliaram a eficácia da cirurgia de blefaroplastia superior associada ou n&at...
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

How to evaluate and acknowledge a scientific journal peer reviewer: a proposed index to measure the performance of reviewers
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - December 18, 2017 Category: Opthalmology Source Type: research

Iris metastases from systemic cancer: a report of three cases
ABSTRACT Standardization of terminologies and methods is increasingly important in all fields including ophthalmology, especially currently when research and new technology are rapidly driving improvements in medicine. This review highlights the range of notations used by vision care professionals around the world for vision measurement, and the challenges resulting from this practice. The global community is urged to move toward a uniform standard.RESUMO Nos tempos atuais, quando a pesquisa e a tecnologia est ão avançando rapidamente, as melhorias na medicina, a padronização de terminologias e ...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

A need for standardization in visual acuity measurement
ABSTRACT Standardization of terminologies and methods is increasingly important in all fields including ophthalmology, especially currently when research and new technology are rapidly driving improvements in medicine. This review highlights the range of notations used by vision care professionals around the world for vision measurement, and the challenges resulting from this practice. The global community is urged to move toward a uniform standard.RESUMO Nos tempos atuais, quando a pesquisa e a tecnologia est ão avançando rapidamente, as melhorias na medicina, a padronização de terminologias e ...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Botulinum toxin for treating unilateral apraxia of eyelid opening in a patient with congenital myotonia
ABSTRACT A 37-year-old female presented with severe apraxia of lid opening (ALO) affecting the right upper lid associated with Becker congenital myotonia (MC). The patient had a history of right upper lid ptosis for 25 years that was exacerbated over the previous month with severe incapacity to open her right eye. No other associated neurological or ophthalmic symptoms were observed. The patient was treated with botulinum toxin (BoNT-A) injection into the pretarsal and lateral canthus region of the orbicularis oculi of the affected eyelid. Treatment with BoNT-A is an effective method of managing ALO in Becker MC. This is t...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Ultrasound biomicroscopy in acetazolamide-induced myopic shift with appositional angle closure
We report a case of a 49-year-old female who presented to the emergency department with blurred vision and vomiting, hours after taking two tablets of 250 mg of acetazolamide. The anterior chamber was bilaterally flat, with normal intraocular pressure in both eyes. An ultrasound biomicroscopic (UBM) examination showed bilateral ciliary effusion and complete appositional angle closure in all quadrants. Acetazolamide-induced bilateral angle closure was diagnosed. Steroid and cycloplegic therapy were initiated, and acetazolamide was discontinued. The following day, the anterior chamber had regained its volume without substant...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Cortical blindness secondary to posterior reversible encephalopathy syndrome, recovered by successful blood pressure management
We report a case of cortical blindness secondary to posterior leukoencephalopathy syndrome, which was successfully treated by blood pressure management. A 66-year-old white man presented at the emergency room complaining of severe frontal headache, disorientation, and progressive blurred vision. The initial physical examination disclosed a blood pressure of 200/176 mmHg. One hour later the patient exhibited mental confusion and bilateral blindness. Computed tomography and magnetic resonance imaging were performed, and a systemic workup was conducted, resulting in a diagnosis of posterior leukoencephalopathy syndrome. This ...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Benign familial fleck retina: multimodal imaging including optical coherence tomography angiography
This report presents multimodal imaging of a 27-year-old woman diagnosed with benign familial fleck retina (OMIM 228980), an uncommon disorder. Fundus photographs revealed retinal flecks that affected her post-equatorial retina but spared the macular area. Fundus autofluorescence and infrared imaging demonstrated a symmetrical pattern of yellow-white fleck lesions that affected both eyes. Her full-field electroretinogram and electrooculogram were normal. An optical coherence tomography B-scan was performed for both eyes, revealing increased thickness of the retinal pigmented epithelium leading to multiple small pigmented e...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Corneal endothelial cell density and pterygium: a cross-sectional study
ABSTRACT Purpose: To investigate the effects of pterygium on corneal endothelial cell density in patients with unilateral pterygium. Methods: We performed a cross-sectional analysis of data from patients with unilateral pterygium who were selected from September 1, 2015 to July 31, 2016 at Hospital de Base do Distrito Federal to assess the corneal endothelial cell density, coefficient of variation in the cell area, hexagonality, and corneal pa ­chymetric results. In all patients, noncontact specular microscopy was performed in both eyes and a minimum endothelial cell count of 75 cells/mm2 was required for inclusion in ...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Intraocular pressure and central corneal thickness in full-term newborns
Conclusions: No relationship was found between CCT and IOP; however, we found a positive association between weight and CCT.RESUMO Objetivo: O objetivo deste estudo foi avaliar a espessura central da c órnea (ECC) e a pressão intraocular (PIO) em recém-nascidos (RN) a termo, correlacionando seus valores entre as variáveis peso, sexo e idade pós-concepção (PCA). Métodos: A pressão intraocular e a espessura central da córnea foram determi­nadas em 52 recém-nascidos a termo com idade ges tacional média de 39,43 ± 1,03 semanas, peso ...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Corneal biomechanical features in patients with ankylosing spondylitis
Conclusion: This study demonstrated a significant negative correlation between corneal hysteresis and disease duration in ankylosing spondylitis patients. Furthermore, the central corneal thickness value decrease d with an increase in Bath Ankylosing Spondylitis Metrology Index score, which may result in an underestimate of intraocular pressure readings and thus an inaccurate risk assessment of glaucoma.RESUMO Objetivo: Avaliar as caracter ísticas biomecânicas da córnea e espessura central da córnea em pacientes com espondilite anquilosante e analisar a correlação destes parâm...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Eyelid fissure dimensions in Japanese and in Brazilians of European descent over 50 years of age
ABSTRACT Purpose: To investigate differences in the palpebral fissure eyelid position in Japanese subjects and in Brazilian subjects of European descent over 50 years of age. Methods: A cross-sectional study evaluating 50 Japanese subjects and 50 Bra ­­­zilian subjects of European descent over 50 years of age was performed to evaluate the effect of aging on eyelid position. Digital photographs were taken with the eyes in the primary position and transferred to a computer to be processed by Scion imaging software for evaluation of palpebral fi ssure width, height, and margin reflex distance (MRD). The data were ...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Aqueous humor concentrations of topical fluoroquinolones alone or in combination with a steroid
ABSTRACT Purpose: To compare the aqueous humor (AH) concentrations of moxifloxacin 0.5% and gatifloxacin 0.3% solutions alone or when treatment was combined with steroids, and to correlate these concentrations with the minimum inhibitory concentrations (MIC) for the most common endophthalmitis-causing organisms. Methods: Patients undergoing phacoemulsification were enrolled to receive one drop of one of the following solutions: moxifloxacin (G1), moxifloxacin + dexamethasone (G2), gatifloxacin (G3), or gatifloxacin + c (G4), every 15 min, 1h before surgery. AH samples were collected before surgery and analyzed using HPLC-t...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Prevalence and associated factors of external punctal stenosis among elderly patients in Turkey
ABSTRACT Purpose: To estimate the prevalence of external punctal stenosis (EPS) in the elderly population and investigate associated factors. Methods: A total of 278 patients ≥ 65 years of age were evaluated for evidence of EPS from January to July 2016. Associated systemic, ocular, demographic, and lifestyle factors were investigated. Multiple logistic regression analyses were applied to evaluate the factors related to having EPS. P values
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Are the effects of hemodialysis on ocular parameters similar during and after a hemodialysis session?
ABSTRACT Purpose: To evaluate the changes in several ocular parameters, including choroidal thickness, during and after hemodialysis. Methods: Twenty-seven eyes of 27 patients with chronic renal failure undergoing hemodialysis were included. The patients underwent an ophthalmic examination, including intraocular pressure, central corneal thickness, iridocorneal angle, subfoveal choroidal thickness, and blood pressure, just before a hemodialysis session, during the second hour of the session, and half an hour after the end of the session. Body weight was measured before and after the session, and ultrafiltration volume was ...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Relationship between anterior segment and optic nerve head parameters in healthy subjects
ABSTRACT Purpose: To determine the relationship between anterior segment and optic nerve head (ONH) parameters. Methods: Two hundred healthy subjects were enrolled in this study. The par ­ticipants underwent measurement of anterior segment parameters with a Pentacam Scheimpflug system and imaging of the optic disc with confocal scanning laser ophthalmoscopy. Pearson ’ s correlation coefficient was calculated to assess the associations between ONH and anterior segment parameters. Multivariate regression analyses controlling for age and disc area as confounding factors were also conducted. Results: There were signi...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Use of the Ishikawa diagram in a case-control analysis to assess the causes of a diffuse lamellar keratitis outbreak
Conclusions: The Ishikawa diagram, like most quality tools, is a visualization and knowledge organization tool. This systematization allowed the investigators to thoroughly assess all the possible causes of DLK outbreak. A clear view of the entire surgical logistics permitted even more rigid management of the main factors involved in the process and, as a result, highlighted factors that deserved attention. The case-control analysis on every factor raised by the Ishikawa diagram indicated that the commonly suspected factors such as biofilm contamination of the water reservoir in autoclaves, the air-conditioning filter syst...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

An investigation of human beta-defensins and cathelicidin expression in patients with pterygium
Conclusions: HBD-2 expression was higher in pterygium specimens than in the controls. HBD-2 expression that might be stimulated by inflammatory cytokines may be related to inflammation and fibrovascular proliferation and may play a role in pterygium pathogenesis.RESUMO Objetivo: Investigar as express ões beta defensinas humanas (HBD) e catelicidina em pacientes com pterígio. Métodos: Nesta série de casos retrospectivos consecutivos, 26 espécimes de pterígio e 15 espécimes conjuntivais normais de 15 indivíduos controle foram investigados. As expressões de HBD-1,...
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

Contribution of medical science in Turkey to the scientific world and the field of ophthalmology
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - November 13, 2017 Category: Opthalmology Source Type: research

A supramolecular look at microenvironmental regulation of limbal epithelial stem cells and the differentiation of their progeny
The objective of this review is to offer perspectives on the supramolecular microenvironmental regulation of limbal epithelial stem cells and the differentiation of their progeny.RESUMO Muitas abordagens t êm sido utilizadas para ampliar entendimentos sobre a regulação microambiental das células tronco epiteliais limbais. Neste contexto, pesquisadores têm exaustivamente investigado a participação de fatores de crescimento, fatores de sobrevida, citocinas, enzimas e moléculas permeáveis secret adas pelas células limbais. Entretanto, evidências recente...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Bilateral acute angle closure in a patient with dengue fever: a case report
We report the case of a 46-year-old female patient who presented with bilateral acute angle closure during the course of dengue infection. Dengue diagnosis was confirmed by serological tests. The patient had plateau iris configuration identified by ultrasound biomicroscopy. This is the second reported case with this condition during dengue fever and the first to describe the characteristics of the angle.RESUMO Os autores relatam o caso de uma mulher de 46 anos que teve fechamento agudo de ângulo bilateral durante a infecção por dengue. O diagnóstico de dengue foi confirmado por testes sorol&oacut...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Choroidal neovascularization silent on optical coherence tomography: report of two cases
ABSTRACT Herein, we report two cases of vision loss after successful cataract surgery, associated with drusenoid retinal pigment epithelial detachment without features of choroidal neovascularization on optical coherence tomography along with angiographic examinations suggestive of choroidal neovascularization in which anatomical and functional improvements were achieved with intravitreal injections of anti-vascular endothelial growth factor.RESUMO Relatamos dois casos de baixa visual ap ós cirurgia bem sucedida de catarata, associada a descolamento drusenóide do epitélio pigmentar da retina (DPED) sem...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Aqueous misdirection syndrome in persistent fetal vasculature (PFV)
We report a case of a 5-year-old girl with persistent fetal vasculature who presented with unilateral acute angle closure caused by aqueous misdirection syndrome that was apparently associated with regression of cycloplegia. Initial treatment with topical steroids, anti-glaucomatous drops, and atropine showed insufficient control of the intraocular pressure (IOP). Surgical treatment with lensectomy and vitrectomy resulted in satisfactory IOP control and no complications at the 6-month follow-up.RESUMO Relatamos o caso de uma crian ça de 5 anos, sexo feminino com persistência do vítreo primário qu...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Optical coherence tomography angiography artifactual choroidal neovascularization in optic disc pit maculopathy
In conclusion, optical coherence tomography angiography may produce artifacts in optic disk pit maculopathy that simulate choroidal neovascularization.RESUMO O presente estudo relatou o caso de um homem caucasiano de 19 anos com diminui ção da acuidade visual no olho direito há 3 meses. Na fundoscopia havia um pit de papila associado ao descolamento seroso macular. A tomografia de coerência óptica identificou uma comunicação entre o pit e o descolamento seroso e a angiografia por tomografia de coerência óptica demonstrou u ma área subfoveal sugestiva de me...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Effects of topical and subconjunctival use of bevacizumab on corneal neovascularization in rabbits' eyes
ABSTRACT Purpose: To evaluate and compare the effects of topical application and subconjunctival injection of bevacizumab on corneal neovascularization (CNV) in rabbits' eyes after chemical burning of the cornea. Methods: The animals were randomly distributed into four groups of five animals. In one group, the drug was instilled, while in another, it was administered by subconjunctival injection. The two procedures using bevacizumab were compared with instillation and subconjunctival injection of saline solution (S). Neovascularization was evaluated according to the size of the invasion area of new blood vessels and throug...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Evaluation of the ocular surface following bariatric surgery
ABSTRACT Purpose: To identify and evaluate changes in the ocular surface in obese patients with bariatric surgery. Methods: The study included 89 randomly selected patients; 81 (91.0%) were women, 35 were preoperative, 32 were included 0-12 months after surgery, and 22 were included>12 months after surgery. All patients completed a dry eye-specific questionnaire and were evaluated by the tear ferning test, tear-film breakup time (BUT), Schirmer's test I, examination of the ocular surface by 1% rose Bengal staining, and impression cytology. Patients were questioned about compliance with nutritional supplementation. Resul...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Surgical amniotic membrane transplantation after conjunctival and limbal tumor excision
Conclusions: AMT was effective for reconstruction of tissue defect after excision and cryotherapy of limbal and conjunctival tumors. In most of these cases, complete healing was achieved with a smooth, stable, and translucent surface.RESUMO Objetivo: Avaliar os resultados cl ínicos de pacientes tratados com transplante de membrana amniótica (TMA) após a excisão de tumores conjuntival e limbar. Métodos: Foram avaliados 14 olhos de 14 pacientes submetidos a transplante de membrana amniótica após excisão total de tumor e crioterapia perilesional. Resultados: Os t umores ...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Assessment of eye drop instillation technique in glaucoma patients
Conclusions: The majority of glaucoma patients were unable to correctly instill eye drops. Age was an independent facto r associated with eye drop instillation performance.RESUMO Objetivo: Avaliar a t écnica de instilação de colírio em portadores de glaucoma e identificar fatores independentes que pode influenciar o desempenho. Métodos: Neste estudo transversal 71 pacientes consecutivos com glaucoma ou hipertensão ocular que auto instilam seus colírios há pelo menos 6 meses, foram avalia dos. Todos os pacientes instilaram um colírio lubrificante no olho de pior...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Dynamic thiol/disulfide homeostasis in patients with age-related macular degeneration
ABSTRACT Purpose: We evaluated dynamic thiol/disulfide homeostasis (TDH), malondialdehyde (MDA) levels, and catalase (CAT) activity in patients with age-related macular degeneration (AMD). All analyzes were conducted on plasma samples. Methods: Thirty-two patients with AMD and 38 age-matched healthy controls were included. Native thiol, total thiol, and disulfide levels and TDH status were determined using a novel, automated assay. MDA levels and CAT activity were determined. Percentages were compared using the chi-squared test. The Student's t-test and Mann-Whitney U-test were used to compare quantitative variables. Resul...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Vitamin D level in patients with pterygium
Conclusion: Vitamin D level in participants with pterygium was significantly increased only in men and in those with more outdoor activity.RESUMO Objetivo: Avaliar os n íveis sanguíneos de vitamina D em pacientes com pterígio. Métodos: Neste estudo prospectivo e comparativo, foram incluídos 58 olhos de 58 indivíduos saudáveis (grupo controle) e 63 olhos de 63 pacientes com pterígio (grupo de estudo). Os indivíduos também foram categorizados quanto ao tem po foi gasto dentro de casa ou ao ar livre. Todos os participantes foram submetidos a exames oft&aacu...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research

Alternative ways to optimize treatment for retinal vein occlusion with peripheral capillary non-perfusion: a pilot study
Conclusions: The combination of ranibizumab injections and peripheral SLP in capillary non-perfusion areas can significantly decrease the number of injections a nd reduce neovascular complications.RESUMO Objetivo: A investiga ção centra-se na terapia de edema macular pós-oclusão da veia retiniana central (OVCR) em casos com isquemia retiniana periférica. O objetivo foi comparar a eficácia e a segurança do tratamento com ranibizumab vs ranibizumab + fotocoagulação com laser de dispersão (SLP) em pacientes com ed ema macular crônico secundário...
Source: Arquivos Brasileiros de Oftalmologia - September 21, 2017 Category: Opthalmology Source Type: research