Nodular anterior scleritis associated with Berger's disease
ABSTRACT A 45-year-old female patient presented with a complaint of right eye redness and pain for 7 days. She was under investigation for urinary abnormalities and reported a previous history of recurrent oral ulcers and ocular hyperemia in both eyes. Best-corrected visual acuity was 20/30 and 20/20 in the right and left eyes, respectively. Slit-lamp biomicroscopy of the ocular surface of the right eye revealed nasal scleral hyperemia that persisted after instillation of topical phenylephrine 10%, reinforcing the diagnosis of anterior scleritis. Renal biopsy showed immunoglobulin A immune complexes and confirmed the suspe...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

High glucose induces pyroptosis of retinal microglia through NLPR3 inflammasome signaling
Conclusions: NOD-like receptor family pyrin domain containing 3 inflammasome signaling may modulate retinal microglia-related inflammation and pyroptosis under high-glucose conditions.RESUMO Objetivo: Atualmente, a retinopatia diab ética é considerada uma doença inflamatória crônica envolvendo a ativação de inflamassomas NLRP3 e piroptose da micróglia da retina. Neste estudo, objetivamos investigar se a sinalização de inflamassomas NLRP3 induz a morte da micróglia da retina sob condições de alta glicose. Métodos : A micróglia da retina foi estimulada por altos níveis de glicose durante 24 horas. A viabili...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Firearm-associated ocular injuries: analysis of national trauma data
Conclusion: Most firearm-associated ocular injuries occurred in young, male, White, and Southern patients. Blacks were disproportionally affected. Most firearm-associated ocular injuries were sight- ­threatening and associated with traumatic brain injury. The majority survived, with potential long-term disabilities. The demographic differences identified in this study may represent potential targets for prevention.RESUMO Objetivo: Os Estados Unidos t êm a maior taxa de posse de armas de fogo de todos os países de alta renda e essas armas foram identificados como uma das maiores causas de trauma ocular e deficiência vi...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Impact of a mobile unit on access to eye care in São Paulo, Brazil
Conclusion: The vast majority of patients presenting to a mobile eye health unit required prescriptions for corrective lenses. The rate of detection of ocular disorders was relatively high and the mobile unit provided effective treatment of refractive errors and referrals for specializ ed ophthalmic examinations and procedures. A mobile eye health unit can be an effective alternative method for improving access to basic eye care, for promoting eye health education and preventing blindness.RESUMO Objetivo: Determinar o impacto do uso de unidade m óvel no acesso à saúde ocular e avaliar o perfil da população que necess...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Codeine plus acetaminophen improve sleep quality, daily activity level, and food intake in the early postoperative period after photorefractive keratectomy: a secondary analysis
Conclusion: The oral combination of codeine and acetaminophen significantly improves sleep quality and daily activity level within the first 24-72 h post-photorefractive keratectomy compared to a placebo.RESUMO Objetivo: Determinar se code ína (30 mg) mais pa­racetamol (500 mg) após ceratectomia fotorrefrativa fornece efeitos benéficos sobre a qualidade do sono, níveis de atividade e ingestão de alimentos além de seu efeito analgésico. Métodos: Quarenta pacientes (80 olhos) foram incluídos neste estudo randomizado, duplo-ce go, pareado, placebo-controlado, add-on. Cada olho foi tratado com 2 semanas de interval...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Use of automated quantitative pupillometric evaluation for monitoring the severity of diabetic retinopathy
Conclusion: This study revealed that the measurements derived from automated pupillometry are altered in patients with type 2 diabetes mellitus. The presence of nonproliferative diabetic retinopathy does not have a negative effect on pupillometry findings, but with proliferative diabetic retinopathy, significant alterations were observed. These results suggest that using automated quantitative pupillometry may be useful in verifying the severity of diabetic retinopathy.RESUMO Objetivos: Procuramos avaliar o uso da pupilometria est ática e dinâmica quantitativa automatizada na triagem de pacientes com diabetes mellitus t...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Prevalence of depressive and anxiety disorders in patients with glaucoma: a cross-sectional study
Conclusion: A significant proportion of patients with glaucoma present with depression and/or anxiety. Females and patients with comorbidities are at greater risk for these disorders.RESUMO Objetivo: Avaliar a preval ência de transtornos de depressão e ansiedade em pacientes com glaucoma e identificar fatores de riscos associados. Métodos: Estudo transversal em pacientes com glaucoma, avaliados durante Agosto de 2016 e Agosto de 2017 no Hospital das Clínicas da Universidade de Campinas e no Hospital Oftalmo lógico de Brasília. Todos pacientes foram submetidos à exame oftalmológico completo para confirmar o diagnÃ...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Thermography in clinical ophthalmic oncology
Conclusions: A thermographic examination of the eye c an be used as an additional first-line diagnostic tool for the differentiation of intraocular tumors. Thermography can be a helpful tool in monitoring the treatment outcome in patients with intraocular melanoma.RESUMO Objetivo: O objetivo deste estudo foi de apresentar a nossa experi ência no uso da termografia como método complementar para o diagnóstico inicial e a diferenciação de tumores intraoculares, bem como para a avaliação da eficácia do tratamento de melanomas intraoculares. Métodos: O grupo estudado compunha-se de 37 pacientes com tumores intraocula...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Association between keratoconus, ocular allergy, and sleeping behavior
Conclusions: The association between higher keratometry values and sleeping position appears to be more significant than that reported between keratometry and itching, or manual dexterity.RESUMO Objetivo: Comparar a gravidade e a lateralidade do ceratocone de acordo com a rinite al érgica, os hábitos de coçar e dormir e a destreza manual. Métodos: Foram realizadas questões objetivas sobre rinite alérgica, prurido ocular e posi­ção do sono em pacientes com ceratocone, diagnosticados com base na tomografia corneana. Esses exames foram analisados e classificados de acor do com a classificação de Amsler-Krumeich. ...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Influence of upper blepharoplasty on intraocular lens calculation
Conclusion: Upper eyelid blepharoplasty influenced intraocular lens calculation using the IOLMaster. However, the influence was not clinically significant. No topographic changes were found using Galilei.RESUMO Objetivo: Determinar o efeito da blefaroplastia superior na topografia corneana e no c álculo do poder das lentes intraoculares usando Galilei e IOLMaster. Métodos: Trinta pacientes submetidos a blefaroplastia superior de maio de 2014 a março de 2017 no Hospital Oftalmológico de Sorocaba, São Paulo, Brasil foram incluídos neste estudo de série de casos observacional. Todos os pacientes foram submetidos a se...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Evaluation of retinal and choroidal microvascular changes in patients who received hydroxychloroquine by optical coherence tomography angiography
Conclusions: Retinochoroidal microvascular flow and vessel density of the macular area were significantly decreased in patients who received hydroxychloroquine. Hy ­droxychloroquine may damage the retinochoroidal mi­cro­vascular architecture. Optical coherence tomography angiography may contribute to the early detection of hy­dro­xychloroquine-induced retinal toxicity.RESUMO Objetivo: O objetivo do estudo foi de avaliar as altera ções microvasculares da retina e da coroide em pacientes sob hidroxicloroquina, através da angiografia por tomografia de coerência óptica. Métodos: Este é um estudo transversal de co...
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Ocular Oncology in Brazil: What is our past, present, and future?
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - January 18, 2021 Category: Opthalmology Source Type: research

Anterior segment optical coherence tomography in pupillary seclusion diagnosis and follow-up
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Utilization of the philtral pressure technique as an efficacious measure to prevent coronavirus transmission through sneezing
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research

Portable devices in ophthalmology
ABSTRACT Age-related macular degeneration is the leading cause of vision loss in elderly individuals, as well as a medical and socio-economic challenge. The treatment of dry age-related macular degeneration is based on vitamin supplementation. New treatment studies are focused on preventing the progression of degeneration and repopulating the atrophic macula. Recently, research on the treatment of neovascular age-related macular degeneration experienced a breakthrough with the advent of anti-vascular endothelial growth factor inhibitors. Nevertheless, despite the fact that ranibizumab, aflibercept, and bevacizumab are effe...
Source: Arquivos Brasileiros de Oftalmologia - January 15, 2021 Category: Opthalmology Source Type: research