Effect of superior blepharoplasty on tear film: objective evaluation with the Keratograph 5M - a pilot study
Conclusions: The results of this pilot study suggest that upper blepharoplasty does not affect tear breakup time according to the objective evaluation of breakup time with the Keratograph 5M.RESUMO Objetivos: Avaliar o efeito da blefaroplastia superior no filme lacrimal, utilizando o top ógrafo de córnea Keratograph 5M. Métodos: Foi realizado estudo prospectivo de 27 olhos de 14 pacientes com dermatocálase superior submetidos à blefaroplastia superior entre maio e junho de 2016. A blefaroplastia palpebral superior conservadora foi realizada por ressecção em bloco de tecido l...
Source: Arquivos Brasileiros de Oftalmologia - October 18, 2018 Category: Opthalmology Source Type: research

Effects of combined oral doxycycline and topical cyclosporine treatment on ocular signs, symptoms, and tear film parameters in rosacea patients
Conclusions: Our results support the finding that topical cyclosporine in addition to the standard regimen improves tear function, as shown by Schirmer test and break-up time scores, in ocular rosacea patients.RESUMO Objetivo: Este estudo relata os efeitos do uso combinado de doxiciclina oral e ciclosporina t ópica sobre sinais e sintomas oculares e sobre parâmetros do filme lacrimal em pacientes com rosácea. Métodos: Cinquenta e quatro olhos direitos de 54 pacientes foram incluídos no estudo. Todos os pacientes foram submetidos a exame oftalmológico completo - incluindo a melhor me...
Source: Arquivos Brasileiros de Oftalmologia - October 18, 2018 Category: Opthalmology Source Type: research

Evaluation of choroidal perfusion changes in obese patients: ocular effects of insulin resistance
Conclusion: We found reduced mean choroidal thickness and ocular pulse amplitude and increased mean intraocular pressure in obese patients. These changes indicated a decrease in choroidal perfusion and ocul ar blood flow. It may be possible to detect ocular blood flow changes in obese patients through noninvasive assessment using the choroid. The negative correlation between insulin resistance and ocular pulse amplitude may be associated with intracellular fat accumulation in obese patients.RESUMO Objetivo: Avaliar as altera ções da perfusão coroidiana em pacientes obesos utilizando tomografia de coer&...
Source: Arquivos Brasileiros de Oftalmologia - October 18, 2018 Category: Opthalmology Source Type: research

On the shoulders of giants
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - October 18, 2018 Category: Opthalmology Source Type: research

Subclinical diabetic macular edema and mild non-proliferative diabetic retinopathy: data correlation with the retinal thickness analyzer (RTA)
CONCLUSION: An increase of mean foveal thickness on diabetic patients who have not shown clinical signs of macular edema was noted, which was proved by statistical tests. Such results are similar to the values found in medical literature . (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Correlation between central corneal thickness and axial length in patients with glaucoma and normal eyes
CONCLUSIONS: The results of this assay suggest that there is no correlation between the central corneal thickness and the axial length in patients with glaucoma and individuals with normal eyes. (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Transcanalicular dacryocystorhinostomy with diode laser
CONCLUSION: Intraoperative and postoperative complications rate were similar of others articles that demonstrated the same surgical technique (with same laser). (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Deep anterior lamellar keratoplasty evaluation in patients with keratoconus
CONCLUSIONS: Although technically challenging with the risk of intraoperative Descemet's membrane perforation, deep anterior lamellar keratoplasty with air dissection technique presents as an option for keratoconus treatment. Confocal microsc opy demonstrated to be a useful method not only for the pachymetry measurement but also for the evaluation of interface by observing the absence of opacities in most of the cases. (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Evaluation of the knowledge that patients with diabetes mellitus demonstrate about ocular changes due to this illness
CONCLUSION: This study demonstrated that 81% of the diabetic patients presents some knowledge about diabetes ocular changes, but they d o not have precise informations. (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Assessing vision-related quality of life in children with bilateral congenital cataracts
OBJETIVO: Avaliar a qualidade de vida relacionada à visão em crianças com catarata congênita bilateral, utilizando o Questionário de Função Visual Infantil (QFVI). MÉTODOS: O QFVI possui duas diferentes apresentações: crianças menores e maiores de 3 anos, sendo dividido em seis domínios: saúde geral, saúde geral da visão, competênci a, personalidade, impacto familiar e tratamento. O QFVI foi aplicado aos pais/cuidadores/responsáveis de crianças com catarata congênita bilateral do Instituto da Vi...
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Therapeutic effect of corneal cross-linking on symptomatic bullous keratophaty
OBJETIVO: Avaliar o efeito do "cross-linking" corneano na ceratopatia bolhosa sintom ática e seu impacto na acuidade visual, espessura corneana e sintomatologia dolorosa. MÉTODOS: Doze pacientes com ceratopatia bolhosa sintomática foram incluídos. Exame clínico com questionário específico para a pesquisa com escala de dor (escala visual analógica numérica), acuidade visual e mensuração da espessura corneana foi realizada pré "cross-linking" corneano, 7, 30 e 60 dias após. Em todos os pacientes o tratamento com UVA...
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Corneal specular microscopy in infectious and noninfectious uveitis
PURPOSE: Involvement of the cornea endothelium during uveitis has not been extensively studied even though it might participate in or constitute a target of ocular inflammation. Formation of keratic precipitates (KP) is a characteristic finding in several forms of uveitis. The aim of this prospective study was to examine the vicinity of keratic precipitates in infectious and noninfectious uveitis by specular microscopy. METHODS: Patients with infectious and noninfectious uveitis in any activity level and presence of keratic precipitates were enrolled. The mean age was 40.5 years ( ± 14.2 years). A Topcon SP-2000P no...
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Incidence and risk factors of retinopathy of prematurity in University Hospital Onofre Lopes, Natal (RN) - Brazil
OBJETIVOS: Determinar a incid ência de retinopatia da prematuridade e avaliar os principais fatores de risco implicados no seu desenvolvimento. MÉTODOS: Estudo coorte retrospectivo de base hospitalar realizado no período de janeiro de 2004 a dezembro de 2006, no Hospital Universitário Onofre Lopes, Natal (RN) - Brasil. A amo stra foi composta por 663 recém-nascidos, com idade gestacional
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Biodegradable systems containing prednisolone acetate for orbital administration
CONCLUSION: The results obtained in this work are relevant and accredi t the system developed as a possible alternative to the treatment of inflammatory orbitopathy. (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Intraocular pressure and ocular rigidity after LASIK
CONCLUSIONS: LASIK reduces IOP readings by GAT but not the ones by ST (differential tonometry). LASIK also diminishes E. IOP (GAT) values are lower at 6 and 24 months. IOP evaluation by ST is more accurate than that by GAT. At 6 months, Vc, Pt and E parameters are stabilized (no changes relatively to 24 months measurements.OBJETIVO: Avaliar comparativamente a press ão intraocular (Po) e a rigidez ocular (E) antes e após 1, 3, 6 e 24 meses em olhos submetidos a LASIK. MÉTODOS: Foram avaliados a Po (pela tonometria de aplanação de Goldmann - TAG e pela tonometria diferencial com os pesos 5,...
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Retinal thickness measurement and evaluation of natural history of the diabetic macular edema through optical coherence tomography
CONCLUSION: This study presents the optical coherence tomography applicability in the detection and semiologic evaluation of diabetic macular edema in patients with visual acuity 20/40 or greater, during one year, showing the retinal thickening in the early stages of diabetic retinopathy. Further, it evidenciated the correlation between the increase in foveal thickness and the reduction in visual acuity. Levels of hemoglobin A1c did not influence the center point thickness data. An early detection of clinically significant macular edema leads us to a redefinition of the real meaning of incipient retinopathy and can prevent...
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Divulgação e certificação da ciência
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 14, 2018 Category: Opthalmology Source Type: research

Intracameral moxifloxacin after cataract surgery: a prospective study
ABSTRACT Nature has always provided an unlimited source of biologically-active compounds. Since the beginning of mankind, humans have sought resources in fauna and flora to treat eye diseases. However, it was only after the Industrial Revolution that extracts of plants and substances of animal origin could be used safely, as has been determined by controlled interventional studies. Two major challenges faced by ocular pharmacology are the following: developing drugs that are able to reduce blindness due to glaucoma; and controlling the pain associated with eye surgery. The search for a drug that effectively lowers intraocu...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Nature as a source of drugs for ophthalmology
ABSTRACT Nature has always provided an unlimited source of biologically-active compounds. Since the beginning of mankind, humans have sought resources in fauna and flora to treat eye diseases. However, it was only after the Industrial Revolution that extracts of plants and substances of animal origin could be used safely, as has been determined by controlled interventional studies. Two major challenges faced by ocular pharmacology are the following: developing drugs that are able to reduce blindness due to glaucoma; and controlling the pain associated with eye surgery. The search for a drug that effectively lowers intraocu...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Ophthalmological findings in ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome: a case report
We report on a case of two sisters, daughters of consanguineous parents, presenting with a similar condition of low visual acuity associated with retinal dystrophy in both eyes associated with alopecia and bone alterations or syndactyly.RESUMO Relatamos um caso de duas irm ãs, filhas de pais consanguíneos, apresentando uma condição semelhante de baixa acuidade visual associado à distrofia retiniana em ambos os olhos associado à alopecia e alterações ósseas ou sindactilia. (Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Exfoliation syndrome associated with LOXL1 gene polymorphisms in a Black patient from Latin America: a case report
ABSTRACT A 89-year-old Black female with a 6-year history of advanced open-angle glaucoma was referred to the Glaucoma Service of the Ophthalmology Department - Federal University of S ão Paulo (UNIFESP). Best-corrected visual acuity was 20/400 in the right eye and 20/60 in the left eye. Pseudoexfoliation material was observed at the iris border, angle, and the anterior lens surface. Anterior biomicroscopy revealed exfoliation material forming an evident peripheral zone and a cen tral disc separated by a clear intermediate zone on the anterior lens surface OU. Gonioscopy showed an open-angle Sampaolesis ’ s li...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

The role of a femtosecond laser in congenital cataract associated with aniridia
ABSTRACT A patient with bilateral aniridia and progressive congenital cataract was treated at the age of 7 years through phacoaspiration with femtosecond laser capsulotomy, in-the-bag intraocular lens implantation, and pars plana vitrectomy (combined with posterior capsulotomy). The diameter of the planned anterior capsulotomy was 4.7 mm; however, due to elevated tension in the young capsular bag, the capsulotomy diameter increased (to around 6 mm) shortly after release of the tension by the laser. In addition, the patient had a very flat and small cornea, causing the formation of air bubbles in the curved laser interface....
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Cilioretinal artery branch avulsion secondary to surgical embolectomy: management and outcome. Case report
We report the trans-operative approach and short-term outcome for a patient who suffered a traumatic avulsion of the cilioretinal artery branch during the surgical management of a cilioretinal arterial branch occlusion with intraocular embolectomy. The patient underwent a pars plana vitrectomy with in situ embolectomy. The blocked artery was incised using 25 Ga vertical scissors, and embolus manipulation was performed using microsurgical forceps. During embolus extraction, the occluded cilioretinal artery and its branch were inadvertently avulsed and torn with subsequent intense bleeding. Laser and endodiathermy were used ...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Oral omega 3 in different proportions of EPA, DHA, and antioxidants as adjuvant in treatment of keratoconjunctivitis sicca in dogs
Conclusion: Oral treatment with ω -3 containing a higher proportion of EPA than DHA increased the effectiveness of topical tacrolimus 0.03% in the treatment of keratoconjunctivitis sicca in dogs.RESUMO Objetivo: Comparar a efic ácia do tacrolimus 0,03% tópico associado ao ômega 3 oral, com diferentes proporções de ácido eicosapentaenoico (EPA), ácidos docosa-hexaenoicos (DHA) e antioxidantes, como adjuvante no tratamento de cães acometidos por ceratoconjuntivite seca. Métodos: Quarenta e cinco cães atendidos no Hospital Veterinário da UNOESTE...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Magnitude of visual impairment, blindness and causes in the southwest region of São Paulo state, Brazil
Conclusion: Visual impairment and blindness in the study population was low and mainly due to cataract and refractive errors. Initiatives should be addressed by health car e services to further reduce avoidable blindness in the region.RESUMO Objetivos: O objetivo deste estudo foi avaliar a mag ­nitude e determinantes da cegueira bilateral e deficiência visual (DV) na região sudoeste do estado de São Paulo, Brasil. Métodos: Trata-se de um estudo transversal do qual participaram pessoas de todas as idades, habitantes de 10 distritos da região sudoeste do estado de São Paulo - Bras...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Retinal changes in rabbit after intravitreal injection of sunitinib encapsulated into solid lipid nanoparticles and polymeric nanocapsules
Conclusions: While nanocapsules intravitreal injections indicated retinal toxic effects, sunitinib and solid lipid nanoparticles intravitreal injections were not toxic to the retina. Our results suggest that a sunitinib preparation with solid lipid nanoparticles for controlled release may offer a significant therapeutic approach for vasoproliferative ocular disease.RESUMO Objetivos: O presente estudo teve por objetivo avaliar a seguran ça da injeção intravítrea de 0,1 ml de sunitinibe em duas concentrações (1 mg/ml e 10 mg/ml), 0,1 ml de dispersão contendo nanopartícu...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Eccentric fixation patterns, clinical findings, and reading speed in patients with bilateral toxoplasmic macular retinochoroiditis
ABSTRACT Purpose: To study visual acuity, refractive errors, eccentric fixation, and reading performance in patients with toxoplasmic macular retinochoroiditis. Methods: Twenty-three participants with bilateral toxoplasmic macular retinochoroiditis and 4 with toxoplasmic macular retinocho ­roiditis in their unique eye were evaluated. Participants reported their eye dominance, confirmed by the Portus and Miles test. Best corrected visual acuity, spherical equivalent refraction, magnification need, and reading speed were measured. Microperimetry (MAIA, Centervue - Padova, Italy) recor ded the preferred retinal locus and ...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Thickness and immunohistochemistry of LASIK flaps created by different femtosecond lasers in eye-bank corneas
ABSTRACT Purpose: The aim of this study was to compare the corneal cell viability and thickness of LASIK flaps created by 3 femtosecond lasers in eye-bank human corneas. Methods: Forty-five eye-bank human sclerocorneal buttons (15 corneas in each group) were examined after the creation of 120 mm-thick laser-assisted keratomileusis (LASIK) flaps with 150kHz iFS In ­traLase ™ (IL), Z6 Femto LDV ™ (LDV), or 200kHz Wavelight ™ FS200 (FS200). The thickness of the flaps was measured using anterior segment optical coherence tomography (AS-OCT; Visante ™ ). Cell viability was blindly evaluated with immu...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Clinical features and corneal optical anisotropies in a rabbit model of limbal stem cell deficiency
Conclusions: These results suggest that rabbit models of limbal stem cell deficiency must be rigorously screened for use in preclinical studies to ensure experimental homogeneity because protocols used to create limbal stem cell deficiency could be not associated with good intra-laboratory reproducibility of clinical features. Limbal stem cell deficiency, as induced herein, altered the optical anisotropic properties of the corneal stroma. Such alterations are indicative of changes in collagen packing and the spatial orientation of glycosaminoglycan chains from proteoglycans. Knowledge of these changes is important to poten...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Induction of pluripotent stem cells by reprogramming human ocular fibroblasts under xeno-free conditions
Conclusions: Sendai virus facilitates induced pluripotent stem cell reprogramming of ocular fibroblasts-both human pterygium and human Tenon ’ s capsule fibroblasts being safe and efficient for induced pluripotent stem cell reprogramming. Although the reprogramming efficiencies of ocular-derived induced pluripotent stem cells under xeno-free conditions were not superior to those observed using the traditional reprogramming system, the cell therapy system reprogramming system is a good option when induced pluripotent stem cells are to be induced under xeno-free conditions.RESUMO Objetivos: Desenvolver um protocolo pad...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Microbiological analysis of contact lens cases: impact of the hospital environment
Conclusion: The types of bacteria contaminating the cases are generally not seen in eye diseases associated with contact lens use, suggesting that other decisive variables are involved in eye infection from a contaminated lens or case. Fungal contamination of contact lens cases appears to be an exception. Ridged cases are commonly used by contact lens wearers and present a potential risk to eye health. In addition, the results of bacterial tests between hospital workers and those who did not visit a hospital were not significantly different.RESUMO Objetivo: O objetivo deste trabalho foi analisar a microbiota bacteriana e f...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Dermis-fat graft for anophthalmic socket reconstruction: indications and outcomes
Conclusion: Dermis-fat graft is an excellent option for congenital or acq uired as well as primary or secondary anophthalmic sockets, with or without contraction. The outcomes are favorable, and complications are rare.RESUMO Objetivo: Avaliar os resultados obtidos com o uso do enxerto dermo-adiposo para reposi ção de volume em cavidade anoftálmica. Métodos: Estudo retrospectivo baseado em revisão de prontuários incluindo todas as cirurgias de enxerto dermo-adiposo realizadas nos últimos 10 anos no King Khaled Eye Specialist Hospital, Saudi Arabia. O enxerto dermo-adiposo foi...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

The effect of smoking cessation on posterior ocular structures
Conclusions: Smoking was associated with statis tically significant changes in paracentral choroidal and central macular thickness in healthy volunteers. Pathological studies should be performed to evaluate the effects of smoking on posterior ocular structures.RESUMO Objetivo: Este estudo avaliou as mudan ças na espessura da coroide e da mácula em voluntários saudáveis e fumantes crônicos. Métodos: Trinta e três olhos de 33 fumantes crônicos (grupo estudado) e 33 olhos de 33 controles saudáveis que nunca fumaram foram avaliados prospectivamente. A avaliaç&a...
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

The number of citations in a scientific journal does not increase through an administrative act
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - September 6, 2018 Category: Opthalmology Source Type: research

Effective dose of bevacizumab for the treatment of retinopathy of prematurity
ABSTRACT Patients undergoing cataract surgery are generally elderly, and many take drugs with systemic effects. The surgeon must be aware of the risks of continuing or discontinuing such medications perioperatively. Antiplatelet drugs and anticoagulants, prescribed to reduce the incidence of thromboembolic events, are often used in this population. This paper aims to review the perioperative use of antiplatelet and anticoagulant drugs in the setting of cataract surgery. Topical or intracameral anesthesia is preferred over anesthesia injected with needles. Aspirin can be safely continued in patients undergoing cataract surg...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Anticoagulants and antiplatelet drugs during cataract surgery
ABSTRACT Patients undergoing cataract surgery are generally elderly, and many take drugs with systemic effects. The surgeon must be aware of the risks of continuing or discontinuing such medications perioperatively. Antiplatelet drugs and anticoagulants, prescribed to reduce the incidence of thromboembolic events, are often used in this population. This paper aims to review the perioperative use of antiplatelet and anticoagulant drugs in the setting of cataract surgery. Topical or intracameral anesthesia is preferred over anesthesia injected with needles. Aspirin can be safely continued in patients undergoing cataract surg...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Focal phototherapeutic keratectomy for the treatment of apical leucoma syndrome
ABSTRACT The following report describes a case of apical leucoma syndrome after hyperopic photorefractive keratectomy following hyperopic laser in situ keratomileusis and the subsequent treatment of this complication with focal phototherapeutic keratectomy. The patient underwent focal transepithelial phototherapeutic keratectomy of 70 mm ablation and 1.5 mm diameter after pupil and ablation offset correction. After 1 year, significant improvement in vision was observed and only slight residual opacity remained on biomicroscopy and optical coherence tomography. Focal phototherapeutic keratectomy was effective and safe for t...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Chronic lacrimal canaliculitis - the answer to a three-year history of red eye
ABSTRACT Chronic lacrimal canaliculitis is a rare infection of the lacrimal system, and can lead to misdiagnosis due to its overlapping presentation to other common entities. The authors report a case of lacrimal canaliculitis with a three-year history of recurrent unilateral red eye and mucopurulent discharge. Here, we describe the clinical course, surgical details, and microbial analysis of canaliculitis infection.RESUMO A canaliculite lacrimal cr ónica é uma infecção rara do sistema lacrimal e pode levar a erros de diagnóstico devido à sua apresentação sobreposta a...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Pseudomonas aeruginosa-induced bilateral endophthalmitis after bilateral simultaneous cataract surgery: case report
This study examines the case of a 77-year-old patient who developed bilateral Pseudomonas aeruginosa endophthalmitis following bilateral simultaneous cataract surgery. Immediate bilateral vitrectomy and intravitreal antibiotics injection were performed. Ultimately, both eyes were eviscerated due to pain refractory to treatment and no light perception.RESUMO A cirurgia bilateral simult ânea de catarata ganhou popularidade entre cirurgiões oftalmológicos em muitos países. Este estudo examina o caso de um paciente de 77 anos que desenvolveu endoftalmite bilateral por Pseudomonas aeruginosa apó...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Classic homocystinuria and keratoconus: a case report
ABSTRACT Homocystinuria is one of a group of genetic disorders called inborn errors of metabolism. It is characterized by a deficiency of the enzyme that converts homocysteine to cystathionine. Keratoconus is an ophthalmologic condition characterized by thinning of the corneal stroma, which causes the cornea to assume a conical shape. There is little information in the scientific literature about the association between keratoconus and homocystinuria. We believe that a collagen cross-linking defect may be the key to understand the connection between these two conditions. This case report describes a 38-year-old male patien...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Scleral necrosis in patients with posterior uveal melanomas evaluated by transcleral fine needle aspiration biopsy and treated by 125I plaque
Conclusions: Thicker posterior uveal melanomas are more likely to develop scleral necrosis after 125I plaque radiotherapy and transcleral fine needle aspiration biopsy. While observation is sufficient for managing limited scleral necrosis, scleral patch graft is a viable alternative for eye preservation in extensive scleral necrosis.RESUMO Objetivo: Avaliar incid ência, possível correlação da biópsia aspirativa com agulha fina trans-escleral e manejo da necrose escleral em pacientes com melanoma da úvea posterior tratados com placa de Iodo-125 (PLACA) avaliados pela biópsia a...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Effects of sub-Tenon’s triamcinolone injections in patients with uveitis
Conclusions: Sub-Tenon ’ s injection of triamcinolone provides reduced macular thickness and improvement in visual acuity with no significant adverse effects and is therefore an effective and safe procedure for the treatment of sequelae of uveitis.RESUMO Objetivos: Avaliar os efeitos da inje ção subtenoniana de triancinolona em pacientes com uveítes. Métodos: Foram incluídos na avaliação 28 olhos com edema macular associado à uveíte. Esses pacientes foram submetidos à injeção subtenoniana de triancinolona e acompanhados ao longo de 18...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Antiscarring effect of intraoperative bevacizumab in experimental glaucoma filtration surgery
ABSTRACT Purpose: To determine the effects of bevacizumab and mitomycin C alone and in combination on intraocular pressure and the scarring process after modified glaucoma filtration surgery in rabbits. Methods: The rabbits underwent modified glaucoma filtration surgery and were allocated into three groups to receive intraoperative treatment with subconjunctival bevacizumab (group A), mitomycin C and subconjunctival bevacizumab (group B), or mitomycin C (group C). Intraocular pressure was measured immediately preoperatively and on postoperative days 8, 14, 17, 21, 26, and 30. The scarring process was assessed 30 days after...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Corneoscleral contact lenses fitting on irregular corneas after laser-assisted in situ keratomileusis
ABSTRACT Purpose: We aimed to describe the outcomes of corneoscleral contact lens fitting with multi-aspherical geometry designs in patients with irregular corneas after laser-assisted in situ keratomileusis (LASIK). Methods: This was a retrospective series of 18 patients (age, 26-38 years) selected from an eye clinic database. Participants were required to have unsatisfactory visual acuity with their current contact lenses or spectacles after LASIK for myopia correction. All patients were fitted with corneoscleral contact lenses designed to correct corneal surface irregularities. A diagnostic trial set was used for fittin...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

A new surgical technique for scleral fixation using a “knot ball” for scleral-fixated intraocular lenses: impact on clinical outcomes
Conclusion: A “ knot ball ” scleral fixation technique is reported; to the best of our knowledge, this is the first report of such a technique, which offers a less invasive and simplified surgical procedure for transscleral fixation of scleral-fixated intraocular lenses. Moreover, the technique appears to display similar effectiveness and safety compared with existing scleral fixation techniques. We suggest that the “ knot ball ” technique warrants further research focus and clinical evaluation in future studies.RESUMO Objetivo: A cirurgia de fixa ção escleral é um procedimento ...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Comparison of the efficacy of 0.03% tacrolimus eye drops diluted in olive oil and linseed oil for the treatment of keratoconjunctivitis sicca in dogs
This study included 60 dogs. Of this group, 20 were healthy and allocated to the control group, and 40 were diagnosed with bilateral KCS and randomly allocated to either the TO (tacrolimus in olive oil) or the TL (tacrolimus in linseed oil) groups. Ophthalmic examinations, Schirmer Tear Test-1 (STT-1), Tear Film Break-up Time (TBUT) and Fluorescein Test (FT) were carried out monthly, along with cytological and histopathological examinations at the beginning and end of the study. Results: The clinical signs, corneal ulcers, Schirmer Tear Test-1 values, and Tear Film Break-up Time values improved in both groups after one mon...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Frequency of ocular diseases among recipients of disability benefits in the metropolitan region of Recife, Brazil
Conclusions: The results highlight the magnitude of the problem of ocular diseases to the social security system, with serious economic and social losses, and emphasize the need for measures aimed at their prevention. Moreover, integration between the national departments of health and social security needs to be improved.RESUMO Objetivo: Identificar a frequ ência das doenças oculares entre os segurados com benefícios por incapacidade. Métodos: Estudo retrospectivo de 217.221 benefícios por incapacidade concedidos pelo Instituto Nacional do Seguro Social (INSS) da gerência executiva ...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Surgical outcomes of rhegmatogenous retinal detachment associated with ocular toxoplasmosis
This study included 22 patients, of which 13 were female (59.1%). The mean age was 28.5 years (SD ± 14.5, range 12-78 years) and the follow-up period varied from 1 to 163 months (mean 64 months). The mean baseline best-corrected visual acuity (BCVA) was 2.0 logMAR (SD ± 1.0). A total of 31 surgeries were performed, and the retina was reattached in 15 patients (68.2%) immediately after the firs t surgery and in 20 patients (90.9%) at a later point. The mean postoperative BCVA improved to 1.3 logMAR (SD ± 0.9) (p
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Peripapillary choroidal thickness in contralateral eyes after evisceration of diseased eyes
Conclusion: Increased peripapillary choroidal thickness was noted in the contralateral eyes of the patients, potentially resulting in a thicker choroid. Although further investigation is required to determine the cause, these findings indicate the presence of a compensatory factor in the contralateral eyes.RESUMO Objetivo: Avaliar as altera ções da espessura coroide peripapilar em olhos contralaterais de pacientes submetidos à evisceração do olho doente. Métodos: Neste estudo retrospectivo, parâmetros da espessura coróide peripapilar de 34 olhos de 34 pacientes submeti...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research

Creation of a childhood glaucoma registry database
Conclusions: Google Forms is a useful tool for collecting and analyzing statistical data, facilitating the process of registering patients, and analyzing information. Usin g the online questionnaire, it will be possible to create a multicenter online database that allows identification of risk factors and evaluation of the outcome of interventions and treatment.RESUMO Objetivo: Este estudo visa a cria ção de um programa para a formação de uma base de dados dos pacientes com diagnóstico de glaucoma pediátrico do Departamento de oftalmologia e ciências visuais da Universidade F...
Source: Arquivos Brasileiros de Oftalmologia - July 11, 2018 Category: Opthalmology Source Type: research