Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression
In this study, we investigated whether G4-ligands suppressed SARS-CoV-2 replication and whether their antiviral activity involved stabilization of viral RNA G4s and suppression of viral gene expression. We found that pyridostatin (PDS) suppressed viral gene expression and genome replication as effectively as the RNA polymerase inhibitor remdesivir. Biophysical analyses revealed that the 25 predicted G4s in the SARS-CoV-2 genome formed a parallel G4 structure. In particular, G4-644 and G4-3467 located in the 5' region of ORF1a, formed a G4 structure that could be effectively stabilized by PDS. We also showed that PDS signif...
Source: Archives of Pharmacal Research - August 10, 2023 Category: Drugs & Pharmacology Authors: Maria Razzaq Ji Ho Han Subramaniyam Ravichandran Jaehyun Kim Joon-Yong Bae Man-Seong Park Shrute Kannappan Woo-Chang Chung Jin-Hyun Ahn Moon Jung Song Kyeong Kyu Kim Source Type: research
Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression
In this study, we investigated whether G4-ligands suppressed SARS-CoV-2 replication and whether their antiviral activity involved stabilization of viral RNA G4s and suppression of viral gene expression. We found that pyridostatin (PDS) suppressed viral gene expression and genome replication as effectively as the RNA polymerase inhibitor remdesivir. Biophysical analyses revealed that the 25 predicted G4s in the SARS-CoV-2 genome formed a parallel G4 structure. In particular, G4-644 and G4-3467 located in the 5' region of ORF1a, formed a G4 structure that could be effectively stabilized by PDS. We also showed that PDS signif...
Source: Archives of Pharmacal Research - August 10, 2023 Category: Drugs & Pharmacology Authors: Maria Razzaq Ji Ho Han Subramaniyam Ravichandran Jaehyun Kim Joon-Yong Bae Man-Seong Park Shrute Kannappan Woo-Chang Chung Jin-Hyun Ahn Moon Jung Song Kyeong Kyu Kim Source Type: research
Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression
In this study, we investigated whether G4-ligands suppressed SARS-CoV-2 replication and whether their antiviral activity involved stabilization of viral RNA G4s and suppression of viral gene expression. We found that pyridostatin (PDS) suppressed viral gene expression and genome replication as effectively as the RNA polymerase inhibitor remdesivir. Biophysical analyses revealed that the 25 predicted G4s in the SARS-CoV-2 genome formed a parallel G4 structure. In particular, G4-644 and G4-3467 located in the 5' region of ORF1a, formed a G4 structure that could be effectively stabilized by PDS. We also showed that PDS signif...
Source: Archives of Pharmacal Research - August 10, 2023 Category: Drugs & Pharmacology Authors: Maria Razzaq Ji Ho Han Subramaniyam Ravichandran Jaehyun Kim Joon-Yong Bae Man-Seong Park Shrute Kannappan Woo-Chang Chung Jin-Hyun Ahn Moon Jung Song Kyeong Kyu Kim Source Type: research
Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression
In this study, we investigated whether G4-ligands suppressed SARS-CoV-2 replication and whether their antiviral activity involved stabilization of viral RNA G4s and suppression of viral gene expression. We found that pyridostatin (PDS) suppressed viral gene expression and genome replication as effectively as the RNA polymerase inhibitor remdesivir. Biophysical analyses revealed that the 25 predicted G4s in the SARS-CoV-2 genome formed a parallel G4 structure. In particular, G4-644 and G4-3467 located in the 5' region of ORF1a, formed a G4 structure that could be effectively stabilized by PDS. We also showed that PDS signif...
Source: Archives of Pharmacal Research - August 10, 2023 Category: Drugs & Pharmacology Authors: Maria Razzaq Ji Ho Han Subramaniyam Ravichandran Jaehyun Kim Joon-Yong Bae Man-Seong Park Shrute Kannappan Woo-Chang Chung Jin-Hyun Ahn Moon Jung Song Kyeong Kyu Kim Source Type: research
Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression
In this study, we investigated whether G4-ligands suppressed SARS-CoV-2 replication and whether their antiviral activity involved stabilization of viral RNA G4s and suppression of viral gene expression. We found that pyridostatin (PDS) suppressed viral gene expression and genome replication as effectively as the RNA polymerase inhibitor remdesivir. Biophysical analyses revealed that the 25 predicted G4s in the SARS-CoV-2 genome formed a parallel G4 structure. In particular, G4-644 and G4-3467 located in the 5' region of ORF1a, formed a G4 structure that could be effectively stabilized by PDS. We also showed that PDS signif...
Source: Archives of Pharmacal Research - August 10, 2023 Category: Drugs & Pharmacology Authors: Maria Razzaq Ji Ho Han Subramaniyam Ravichandran Jaehyun Kim Joon-Yong Bae Man-Seong Park Shrute Kannappan Woo-Chang Chung Jin-Hyun Ahn Moon Jung Song Kyeong Kyu Kim Source Type: research
Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression
In this study, we investigated whether G4-ligands suppressed SARS-CoV-2 replication and whether their antiviral activity involved stabilization of viral RNA G4s and suppression of viral gene expression. We found that pyridostatin (PDS) suppressed viral gene expression and genome replication as effectively as the RNA polymerase inhibitor remdesivir. Biophysical analyses revealed that the 25 predicted G4s in the SARS-CoV-2 genome formed a parallel G4 structure. In particular, G4-644 and G4-3467 located in the 5' region of ORF1a, formed a G4 structure that could be effectively stabilized by PDS. We also showed that PDS signif...
Source: Archives of Pharmacal Research - August 10, 2023 Category: Drugs & Pharmacology Authors: Maria Razzaq Ji Ho Han Subramaniyam Ravichandran Jaehyun Kim Joon-Yong Bae Man-Seong Park Shrute Kannappan Woo-Chang Chung Jin-Hyun Ahn Moon Jung Song Kyeong Kyu Kim Source Type: research
