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The Pathology Job Market Post-COVID-19-Where Are We Now? A Comparison of Pathology Job Advertisements From 2013-2017 to 2018-2022
Arch Pathol Lab Med. 2023 Nov 1;147(11):1227-1228. doi: 10.5858/arpa.2023-0211-LE.NO ABSTRACTPMID:37870250 | DOI:10.5858/arpa.2023-0211-LE (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - October 23, 2023 Category: Laboratory Medicine Authors: Debra L Zynger Nat Pernick Source Type: research

Establishment of a Labile Bound Copper Reference Interval in a Healthy Population via an Inductively Coupled Plasma Mass Spectrometry Dual Filtration-Based Assay
CONCLUSIONS.—: Sex-specific reference intervals have now been established for LBC and LBC fraction. These data in conjunction with further testing of WD populations can be used to assess the sensitivity and specificity of LBC fraction in screening, monitoring, and diagnosis.PMID:37870242 | DOI:10.5858/arpa.2023-0259-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - October 23, 2023 Category: Laboratory Medicine Authors: Anna C Bitzer Jessica Fox Patrick L Day Vanessa K Pazdernik Carin Y Smith Michelle Wermers Paul J Jannetto Joshua A Bornhorst Source Type: research

Implementation, Evolution, and Laboratory Performance of Methods-Based Proficiency Testing for Next-Generation Sequencing Detection of Germline Sequence Variants
CONCLUSIONS.—: Since the inception of this program, laboratories have consistently performed well. The median sensitivity and specificity of detection of sequence variants included in this program (eg, single nucleotide variants, insertions, and deletions) were 100.0%.PMID:37852169 | DOI:10.5858/arpa.2023-0090-CP (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - October 18, 2023 Category: Laboratory Medicine Authors: Karen D Tsuchiya Birgit Funke Madhuri Hegde Avni Santani Rhona J Souers Szabolcs Szelinger Jaimie Halley Qin Zhao Nicole Mot Angshumoy Roy Vanessa L Smith Bing M Zhang Karl Voelkerding Ann M Moyer Source Type: research

The Secret Life of Junior Pathologists
CONCLUSIONS.—: This study identified challenges experienced by junior pathologists. Collective efforts from training programs, experienced pathologists, and professional organizations can explore ways to improve the transition experience.PMID:37852170 | DOI:10.5858/arpa.2023-0195-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - October 18, 2023 Category: Laboratory Medicine Authors: DongHyang Kwon Mehran Taherian Den ái R Milton Paula Iaeger Kareen Chin Phyu P Aung Source Type: research

A Deep Learning-Based Approach to Estimate Paneth Cell Granule Area in Celiac Disease
CONCLUSIONS.—: Crypt hyperplasia was confirmed in CD compared to non-CD controls. The area of Paneth cell granules, an indirect measure of Paneth cell function, decreased with increasing severity of CD. More importantly, our study analyzed complete hematoxylin-eosin slide sections using an efficient and easy to use coding-free artificial intelligence workflow.PMID:37852171 | DOI:10.5858/arpa.2023-0074-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - October 18, 2023 Category: Laboratory Medicine Authors: Ebtihal Alharbi Ajay Rajaram Kevin C ôté Mina Farag Farhad Maleki Zu-Hua Gao Chelsea Maedler-Kron Victoria Marcus Pierre Olivier Fiset Source Type: research

Pathologic Findings in Severe Coal Workers' Pneumoconiosis in Contemporary US Coal Miners
CONCLUSIONS.—: Silica-related pathologies are more common in contemporary miners. Severe forms of CWP can be detected by subtyping PMF lesions (if present) or by identification of mature and immature silicotic nodules, coal mine dust-related alveolar proteinosis, and severe inflammation in coal miners' lungs. Silica-type PMF cases showed significantly higher levels of MDAP than either mixed- or coal-type PMF (P < .001). High profusion of birefringent silica/silicate particles was observed more frequently in cases with immature (early stage) silicotic nodules (P = .04). Severe inflammation was also significantly increa...
Source: Archives of Pathology and Laboratory Medicine - October 18, 2023 Category: Laboratory Medicine Authors: Carlyne D Cool Jill Murray Naseema I Vorajee Cecile S Rose Lauren M Zell-Baran Soma Sanyal Angela D Franko Kirsten S Almberg Cayla Iwaniuk Leonard H T Go Francis H Y Green Robert A Cohen Source Type: research

Alternative Strategies to Provide Actionable Results When Supply of Urinalysis Strips Is Unavailable
CONCLUSIONS.—: During urine strip shortages, we successfully implemented a diversion algorithm that provided actionable urinalysis analytes in a timely manner with minimal provider complaints.PMID:37852173 | DOI:10.5858/arpa.2023-0217-OA (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - October 18, 2023 Category: Laboratory Medicine Authors: Jeannette Guarner Geoffrey H Smith David N Alter Cecellitha J Williams Lisa Cole Davette G Campbell Suzanne M Elsea Stacian Reynolds Christine Lawrence Source Type: research