Long-term benefits and risks of parathyroid hormone treatment in compliant osteoporotic patients. A Danish national register based cohort study
ConclusionOverall, PTH treatment is effective and safe. Following PTH treatment in compliant patients, neither fracture incidence nor drug consumption differed between PTH-treated and BP-treated patients, despite the fact that PTH-treated patients had more severe osteoporosis. No increased incidence of malignant diseases or other diseases was detected. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - May 2, 2018 Category: Orthopaedics Source Type: research

Age and gender differences in the prevalence and correlates of vitamin D deficiency
This study ’s objective was to measure the prevalence of vitamin D deficiency and determine its correlates among Saudi adults in Riyadh, Saudi Arabia.MethodsA cross-sectional study was conducted with 2835 Saudi males and females aged 30 –75 years in 18 different primary health care centers (PHCC) in Riyadh. Detailed interviews on sociodemographic and lifestyle factors and anthropometric measurements were conducted. Serum calcium, phosphorus, parathyroid, alkaline phosphatase, and 25(OH) vitamin D were measured. Multiple logistic regression analyses were conducted.ResultsThe mean age (SD) of male and female...
Source: Archives of Orthopaedic and Trauma Surgery - April 29, 2018 Category: Orthopaedics Source Type: research

Association between metabolic syndrome and osteoporosis in Taiwanese middle-aged and elderly participants
ConclusionsAfter BMI stratification and adjustments for age, nutrition status, liver and renal functions, and exercise status, we found no significant association between MS and osteoporosis in either gender. Regular exercise may prevent osteoporosis, particularly in men with a lean body mass. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 28, 2018 Category: Orthopaedics Source Type: research

Infection following percutaneous vertebral augmentation with polymethylmethacrylate
ConclusionsAlthough the incidence of infection following vertebroplasty or kyphoplasty is rare, postoperative infection and cement augmentation in preexisting spondylitis can develop into a life-threatening complication in frail patients with notable comorbidities. In treating infected vertebroplasty and kyphoplasty, immediate culture and biopsy and the long-term use of proper antibiotics are critical. Prompt surgical treatment should be considered in case of significant neurologic deficit, severe instability due to infected fracture, and resistance to antibiotics. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 27, 2018 Category: Orthopaedics Source Type: research

Treatment costs and cost drivers among osteoporotic fracture patients in Japan: a retrospective database analysis
ConclusionsYearly treatment costs were increased considerably after fracture. Several comorbidities were considered to be cost drivers for osteoporotic fracture treatment. The cost estimates with different patient profile would support conducting health economic analysis in the future. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 25, 2018 Category: Orthopaedics Source Type: research

Association between alcohol consumption and bone mineral density in elderly Korean men and women
AbstractSummaryIn this cross-sectional study based on Korean elderly men and women, heavy alcohol intake for men was related to low whole-body BMD and light alcohol intake for women was associated with high whole-body, lumbar, and total femur BMD.PurposeAlcohol is a risk factor of osteoporosis but previous studies on its effect on bone health has been controversial. The aim of this study was to evaluate the association between alcohol intake and bone mineral density in Korean elderly men and women.MethodsBased on the Fourth and Fifth Korean National Health and Nutrition Examination Surveys (KNHANES), 2657 men and 2080 wome...
Source: Archives of Orthopaedic and Trauma Surgery - April 25, 2018 Category: Orthopaedics Source Type: research

Mild cognitive impairment is associated with poor physical function but not bone structure or density in late adulthood: findings from the Hertfordshire cohort study
This study investigated the association between mild cognitive impairment (MCI) and physical function and bone health in older adults. MCI was associated with poor physical performance but not bone mineral density or bone microarchitecture.PurposeCross-sectional study to investigate the association between mild cognitive impairment (MCI) and physical performance, and bone health, in a community-dwelling cohort of older adults.MethodsCognitive function of 222 men and 221 women (mean age 75.5 and 75.8  years in men and women, respectively) was assessed by the Strawbridge questionnaire and Mini Mental State Exam (MMSE). ...
Source: Archives of Orthopaedic and Trauma Surgery - April 24, 2018 Category: Orthopaedics Source Type: research

Sports participation and fracture in older Australian men
ConclusionsIn this group of older men, participation in sporting activity was associated with a reduced risk of fracture during the subsequent follow-up period. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 19, 2018 Category: Orthopaedics Source Type: research

Epidemiology of hip fracture in Belarus: development of a country-specific FRAX model and its comparison to neighboring country models
ConclusionA substantial proportion of hip fractures in Belarus does not come to hospital attention. The FRAX model should enhance accuracy of determining fracture probability among the Belarus population and help guide decisions about treatment. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 17, 2018 Category: Orthopaedics Source Type: research

Do reductions in out-of-pocket expenses for dual energy X-ray absorptiometry scans translate to reduced fracture incidence amongst older Australians? A population-based study
ConclusionThe change in reimbursement guidelines appears to have had little impact on reducing fracture incidence during this time frame for elderly men and women, in fact, fracture rates increased. Future research should investigate osteoporosis management following DXA over a longer time frame. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 14, 2018 Category: Orthopaedics Source Type: research

A low phase angle measured with bioelectrical impedance analysis is associated with osteoporosis and is a risk factor for osteoporosis in community-dwelling people: the Yakumo study
AbstractSummaryAlthough the phase angle has been reported to be related to predictive factors and therapeutic effects in various diseases, its relation with osteoporosis is unclear. In our large prospective survey of community-dwelling people, a low phase angle was related with osteoporosis, and it could be a predictor of osteoporosis.PurposeThe phase angle measured with bioelectrical impedance analysis (BIA) is one of the clinically important impedance parameters, and it is a predictor of prognosis and mortality for several diseases. The present cross-sectional study aimed to elucidate the association between osteoporosis...
Source: Archives of Orthopaedic and Trauma Surgery - April 5, 2018 Category: Orthopaedics Source Type: research

Decreased bone turnover in HIV-infected children on antiretroviral therapy
ConclusionsOur findings suggest that in HIV-infected children with viral suppression, decreased bone accrual may occur or persist independent of immune activation and altered bone turnover. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 5, 2018 Category: Orthopaedics Source Type: research

Fracture risk prediction using FRAX in patients following hematopoietic stem cell transplantation
ConclusionsIn patients greater than 50  years, the FRAX tool has modest predictive ability and could be used to aid in preventive treatment decision-making at the time of transplant. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 4, 2018 Category: Orthopaedics Source Type: research

Estimated expenditures for hip fractures using merged healthcare insurance data for individuals aged ≥ 75 years and long-term care insurance claims data in Japan
AbstractSummaryLittle is known about hip fracture expenditure in Japan. Using claims data obtained from a core city near Tokyo, we estimated the mean healthcare expenditure and monthly long-term care expenditure post-hip fracture to be ¥2,600,000 (US$29,500) and ¥113,000 (US$1290), respectively.PurposeWe aimed to estimate healthcare and long-term care expenditures post-hip fracture in Japan.MethodsHealthcare insurance claims data for adults aged≥ 75 years were merged with long-term care insurance claims data. We analyzed the data of hip fracture patients who were admitted to non-diagnosis procedure combinat...
Source: Archives of Orthopaedic and Trauma Surgery - March 30, 2018 Category: Orthopaedics Source Type: research

Assessment of dietary calcium intake of university students: a pilot study in Turkey
AbstractSummaryThe aim of this study was to adapt the rapid assessment method (RAM) and International Osteoporosis Foundation Food Frequency Questionnaire (IOF FFQ) tools, used for the assessment of daily calcium intake in university students, and to compare the data obtained using 24-h recall (24-HR) data. There was a moderate positive correlation between the RAM and IOF.Purpose/introductionCalcium is an essential mineral that plays vital roles in metabolism and it is very important to accurately assess the amount of calcium intake on the diet. It was aimed to assess the daily calcium intake of university students by two ...
Source: Archives of Orthopaedic and Trauma Surgery - March 30, 2018 Category: Orthopaedics Source Type: research

Scientific output quality of 40 globally top-ranked medical researchers in the field of osteoporosis
AbstractSummaryThe study presents the research output of 40 globally top-ranked authors, publishing in the field of osteoporosis. Theirh-index is compared with the Scientific Quality Index (SQI), a novel indicator. Using SQI, 92.5% of the authors changed their initial positions in the general ranking. SQI partially depends on bibliometric measures different from those influencingh-index and may be considered as an assessment tool, reflecting more objective, qualitative, rather than quantitative, features of individual scientific output.PurposeThe study approaches the research output of 40 globally top-ranked authors in the...
Source: Archives of Orthopaedic and Trauma Surgery - March 26, 2018 Category: Orthopaedics Source Type: research

Treatment patterns in patients with osteoporosis at high risk of fracture in Japan: retrospective chart review
ConclusionsA high percentage of patients (87.9%) in Japan received OP medications soon after their high-risk diagnosis, with bisphosphonates, selective estrogen receptor modulators and teriparatide being the predominant treatment options. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 22, 2018 Category: Orthopaedics Source Type: research

Real-world effectiveness of osteoporosis therapies for fracture reduction in post-menopausal women
ConclusionIn summary, reductions in fracture incidence over time were observed in cohorts of patients treated with osteoporosis therapies. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 21, 2018 Category: Orthopaedics Source Type: research

Risk factors predicting subsequent falls and osteoporotic fractures at 4  years after distal radius fracture—a prospective cohort study
ConclusionPrior falls ( ≥ 2) is an independent predictor of subsequent falls in patients with DRF. In clinical practice, screening of patients for prior falls, balance, fracture-specific pain/disability, and BMD may identify those who might be at risk of subsequent falls after their first DRF. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 20, 2018 Category: Orthopaedics Source Type: research

Physical activity, but not sedentary time, influences bone strength in late adolescence
We examined relations between PA and sedentary time and bone outcomes, adjusting for ethnicity, maturity, tibial length, and total body lean mass.ResultsAt the distal tibia, MVPAAccel and VPAAccel positively predicted BSI (explained 6 –7% of the variance,p 
Source: Archives of Orthopaedic and Trauma Surgery - March 20, 2018 Category: Orthopaedics Source Type: research

Impact of cumulative exposure to high-dose oral glucocorticoids on fracture risk in Denmark: a population-based case-control study
We examined the effect of cumulative exposure to high doses of oral glucocorticoids on fracture risk. Compared to short-course users (daily dose ≥ 15 mg + cumulative
Source: Archives of Orthopaedic and Trauma Surgery - March 18, 2018 Category: Orthopaedics Source Type: research

Weather conditions and their effect on seasonality of incident osteoporotic hip fracture
The objective of this work is to evaluate seasonality and the effect of weather conditions on the incidence of osteoporotic hip fracture in a Southern European region.MethodsThis retrospective cohort study included all patients admitted to Alcorc ón Foundation University Hospital with a diagnosis of osteoporotic hip fracture between the years 1999 and 2015. In a time series analysis, we examined the association between hip fracture incidence and different weather conditions and seasonality using general additive models (with Poisson distrib ution). The incidence rate ratio (IRR) crude and adjusted by season was esti...
Source: Archives of Orthopaedic and Trauma Surgery - March 15, 2018 Category: Orthopaedics Source Type: research

Bone: best papers of the year 2017
ConclusionsThese papers offer a hopeful outlook for a better treatment and management of patients with osteoporosis and other metabolic bone diseases anno 2018. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 15, 2018 Category: Orthopaedics Source Type: research

The burden of inpatient care for diabetic and non-diabetic patients with osteoporotic hip fractures —does it differ? An analysis of patients recruited into a fracture liaison service in Southeast Asia
AbstractSummaryHospital care and mortality of diabetic and non-diabetic osteoporotic Asian patients undergoing hip fracture surgery were explored with no difference in length of hospitalization, incidence of post-operative complications, or mortality between diabetics and non-diabetics seen. Time to operation correlated with post-operative complications occurrence and therefore surgery should be expeditiously done.IntroductionWhether burden of inpatient care, problems after admission, and mortality rates differ between diabetics and non-diabetics undergoing surgery for osteoporotic hip fractures has not been explored in As...
Source: Archives of Orthopaedic and Trauma Surgery - March 15, 2018 Category: Orthopaedics Source Type: research

Medical optimization of lumbar fusion in the osteoporotic patient
ConclusionsOverall, the current body of research appears to support the use of teriparatide therapy to enhance lumbar fusion outcomes in the osteoporotic patient, although the extent of research on this topic is limited. Additionally, very little evidence exists to cease any of the mentioned osteoporosis treatments prior to lumbar fusion. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 14, 2018 Category: Orthopaedics Source Type: research

Hyperkyphotic measures using distance from the wall: validity, reliability, and distance from the wall to indicate the risk for thoracic hyperkyphosis and vertebral fracture
ConclusionC7WD is valid and reliable with good diagnostic properties for thoracic hyperkyphosis and vertebral fracture. The findings confirm the use of C7WD using traditional ruler-based method as a practical tool to screen and monitor severity of thoracic hyperkyphosis in clinics and communities. In addition, the measurement using the IG-KypDisT provided accurate data that can be saved for further analysis; it is therefore suggested for research settings. The findings would promote the standardization of hyperkyphosis measurements in various settings. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 12, 2018 Category: Orthopaedics Source Type: research

The vitamin D receptor expression in skeletal muscle of women with distal radius fracture
ConclusionsDRF patients with low appendicular lean mass index presented high VDR expression and low CSA in forearm muscle cells. This suggests that the VDR expression might be upregulated in the attempt to compensate for the decreasing muscle mass. Further studies are necessary to explore the role of VDR in the progression of sarcopenia. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 12, 2018 Category: Orthopaedics Source Type: research

Decreasing trend of hip fractures incidence in Italy between 2007 and 2014: epidemiological changes due to population aging
ConclusionWhile the number of hospitalizations for hip fractures in Italy is still increasing due to the fractures occurring in people ≥ 85 years old, incidence rates are decreasing in all the age groups, including the oldest one, possibly because the number of subjects aged ≥ 85 is growing faster than the number of fractures. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 9, 2018 Category: Orthopaedics Source Type: research

The burden and undertreatment of fragility fractures among senior women
ConclusionFF was frequently reported among senior women as an important cause of physical disability. However, the prevalence of OP treatment was low, which constitutes a public health problem in this vulnerable group. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 7, 2018 Category: Orthopaedics Source Type: research

Experiences of being diagnosed with osteoporosis: a meta-synthesis
ConclusionsThis meta-synthesis provides knowledge for health professionals on the experiences and perspectives of being diagnosed with osteoporosis from the patient ’s point of view. The experience, meaning and significance of osteoporosis must be taken into consideration and can be used to promote tailored and targeted information and guidance on osteoporosis, bone care and treatment at different stages of the osteoporosis trajectory. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 6, 2018 Category: Orthopaedics Source Type: research

Higher step count is associated with greater bone mass and strength in women but not in men
ConclusionObserved significant positive associations between daily steps and various bone traits at the calcaneus, tibia, and radius in women suggest that habitual physical activity may benefit skeletal health in adulthood. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 6, 2018 Category: Orthopaedics Source Type: research

Sleep apnea and femoral neck BMD among Singaporean mid-life women
This study explored the relationship between sleep apnea and femoral neck BMD in midlife Asian women. Partner-witnessed apnea predicted higher femoral neck BMD, an effect validated by the STOP index. Our findings suggest that sleep apnea may protect bone health.PurposeThe menopause transition is associated with decline in bone mineral density (BMD) and sleep quality. However, any relationship between these two factors remains controversial. This study explored the association between sleep apnea and femoral neck BMD in middle-aged women.MethodsParticipants (n = 1201) aged 45–69 years attending well...
Source: Archives of Orthopaedic and Trauma Surgery - March 5, 2018 Category: Orthopaedics Source Type: research

Microstructural properties of trabecular bone autografts: comparison of men and women with and without osteoporosis
ConclusionsPost-menopausal women and older men with OP have worse bone quality in autografts than non-osteoporotic men and women. Postmenopausal women with OP presented serious microarchitectural deterioration in older population (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 5, 2018 Category: Orthopaedics Source Type: research

Bone mineral density and nutritional status in children with quadriplegic cerebral palsy
ConclusionThere was a significant relationship between low BMD, degree of motor impairment, method of feeding, and malnutrition. Optimizing these factors could reduce the risk of osteopenia and osteoporosis and attain a significant improvement of quality of life in children with quadriplegic CP. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 4, 2018 Category: Orthopaedics Source Type: research

Epidemiology and correlates of osteoporotic fractures among type 2 diabetic patients
ConclusionThis large population-based study confirms the higher fracture risk of osteoporotic patients with T2DM, as compared to osteoporotic patients without T2DM, despite higher bone mineral density levels. The presence of micro- and macrovascular disease appears to increase this risk. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 3, 2018 Category: Orthopaedics Source Type: research

Smoking and bone mineral density: comprehensive analyses of the third National Health and Nutrition Examination Survey (NHANES III)
ConclusionsNon-linearity is an unlikely explanation for inconsistent results in the literature on smoking and bone mineral density. Further and especially longitudinal studies of the complex relationship smoking with bone health would be particularly important given the still substantial prevalence of smoking in an aging global population. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 3, 2018 Category: Orthopaedics Source Type: research

25-Hydroxyvitamin D levels and bone mineral density evaluation in patients with cholecystectomy: a case-control study
ConclusionIn the light of our results, cholecystectomy patients seem to have lower level of 25(OH) D levels in comparison with healthy subjects, but both groups have similar BMD values. Further studies in cohort designs taking into account the bone formation and resorption markers are awaited. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 2, 2018 Category: Orthopaedics Source Type: research

Morphometric semi-quantitative assessment of vertebral fractures in postmenopausal black women in Central Africa
ConclusionThis study seemed to determine the pattern and features of vertebral fractures in black African women which may be useful for comparisons with the pattern of worldwide populations. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 1, 2018 Category: Orthopaedics Source Type: research

Incidence and risk factors of medical complications and direct medical costs after osteoporotic fracture among patients in China
ConclusionsOsteoporotic fractures led to amount of medical complications, which significantly increased patients ’ economic burden. Complications correlate to various factors such as patients’ disease history. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - February 27, 2018 Category: Orthopaedics Source Type: research

Bone metabolism markers and vitamin D in adolescent cyclists
This study aimed to describe bone metabolic activity in adolescent competitive cyclists compared to age-matched controls. The main result is that younger subjects present a higher bone turnover than the older ones. Moreover, cyclists under the age of 17 have higher scores on all markers than age-matched controls.PurposeThe purpose of this study was to describe bone metabolic activity in adolescent competitive cyclists compared to age-matched controls.MethodsTwenty-two male adolescent cyclists between 14 and 20  years (y) and 20 age-matched controls participated in this study. Serum osteocalcin (OC), aminoterminal prop...
Source: Archives of Orthopaedic and Trauma Surgery - February 3, 2018 Category: Orthopaedics Source Type: research

Self-reported protein intake and properties of bone in community-dwelling older individuals
This study revealed that a quick and simple estimation of protein intake was related to measures of bone density and area in 70-year-old individuals. Furthermore, these associations were mediated by muscle mass when investigating peripheral measurement sites such as arms and legs.PurposeRecent evidence suggests that dietary protein is beneficial for bone health in older individuals, but less is known about the influence of muscle mass on this relationship. This cross-sectional study aimed to investigate associations among protein intake, bone health, and muscle mass in 2332 men and women aged 70  years.MethodsVolumetr...
Source: Archives of Orthopaedic and Trauma Surgery - January 31, 2018 Category: Orthopaedics Source Type: research

Dairy product intake and bone properties in 70-year-old men and women
ConclusionNo evidence of a negative association between dairy product consumption and bone health was found. Furthermore, total dairy product consumption was associated with increased CSAs in the tibia, regardless of dairy product type. Collectively, our findings indicate the existence of a weak but significant positive association between dairy product consumption bone properties in older adults. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - January 29, 2018 Category: Orthopaedics Source Type: research

Investigating the bone mineral density in children with solid tumors in southern Iran: a case –control study
ConclusionVitamin D deficiency and low bone mass are prevalent among Iranian children with solid tumors. Future studies are warranted to investigate the best strategies to prevent and treat vitamin D deficiency and low bone mass in children surviving cancer. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - January 26, 2018 Category: Orthopaedics Source Type: research

“We get them up, moving, and out the door. How do we get them to do what is recommended?” Using behaviour change theory to put exercise evidence into action for rehabilitation professionals
ConclusionsKey barriers to implementing the recommendations are rehabilitation professionals ’ ability to use behaviour change techniques, to modify the recommendations for physical and cognitive limitations and to feel comfortable with delivering challenging but safe interventions for people with osteoporosis, and lacking trust and team work across sectors. Future work will report on dev elopment and evaluation of knowledge translation interventions informed by our study. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - January 25, 2018 Category: Orthopaedics Source Type: research

Are we treating osteoporotic fractures of the hip adequately? A Middle Eastern cohort study
ConclusionsLess than 27% patients receive BMD test following fragility fracture of the hip and only 6% a vit D3 assay. Secondary fractures of the hip tend to occur in approximately 9% of the cases in Oman; this seems to occur equally in patients who have had as well as not had any calcium and vit D supplements after the index injury. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - January 24, 2018 Category: Orthopaedics Source Type: research

Upright activity and higher motor function may preserve bone mineral density within 6  months of stroke: a longitudinal study
ConclusionBetter motor control and walking recovery were associated with reduced bone loss. Interventions targeting these impairments from early post-stroke are warranted.Clinical trial registrationURL:http://www.anzctr.org.au. Unique identifier: ACTRN12612000123842. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - January 8, 2018 Category: Orthopaedics Source Type: research

Diet and exercise changes following bone densitometry in the Patient Activation After DXA Result Notification (PAADRN) study
ConclusionsBone health behaviors improved, on average, over 52  weeks among all participants following a DXA. Receipt of the PAADRN letter and educational brochure did not directly improve bone health behaviors compared to usual care.Trial registrationThe Patient Activation after DXA Result Notification (PAADRN) Study is registered at ClinicalTrials.Gov: NCT01507662,https://clinicaltrials.gov/ct2/show/NCT01507662 (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - January 6, 2018 Category: Orthopaedics Source Type: research

Difference of clinical course between cases with bone union and those with delayed union following osteoporotic vertebral fractures
AbstractSummaryIn this prospective multicenter study of osteoporotic vertebral fractures (OVFs), delayed union of OVF at 6-month follow-up caused prolonged pain, QOL impairment, ADL impairment, cognitive status deterioration, and vertebral collapse progression.PurposeDelayed union following osteoporotic vertebral fracture displayed as an intravertebral cleft on plain X-rays was reported to be a factor for prolonged severe pain. However, the difference of clinical course between bone union and delayed union cases still remains unclear. The purpose of this study was to identify how OVF delayed union following conventional co...
Source: Archives of Orthopaedic and Trauma Surgery - December 28, 2017 Category: Orthopaedics Source Type: research

The QUALYOR (QUalit é Osseuse LYon Orléans) study: a new cohort for non invasive evaluation of bone quality in postmenopausal osteoporosis. Rationale and study design
ConclusionsQUALYOR will provide important information on the relationship between bone quality variables and fracture risk in women with moderately decreased BMD. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - December 27, 2017 Category: Orthopaedics Source Type: research

Medication-taking behaviour in Bulgarian women with postmenopausal osteoporosis treated with denosumab or monthly oral bisphosphonates
This study aimed to describe medication-taking behaviour in women with osteoporosis, prescribed denosumab or oral ibandronate, in Bulgarian clinical practice.MethodsThis retrospective, observational, multicentre chart review (with up to 24  months follow-up) enrolled postmenopausal women initiating 6-monthly denosumab injection or monthly oral ibandronate treatment for osteoporosis between 1 October 2011 and 30 September 2012.ResultsOverall, 441 women were enrolled (224 had initiated denosumab, 217 had initiated ibandronate). At baseline, more women in the denosumab group than in the ibandronate group had a previous f...
Source: Archives of Orthopaedic and Trauma Surgery - December 21, 2017 Category: Orthopaedics Source Type: research