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Fracture risk in Asian-Canadian women is significantly over-estimated by the Canadian Association of Radiologists-Osteoporosis Canada risk prediction tool: retrospective cohort study
ConclusionIn Asian-Canadian women, observed osteoporosis fracture rates are lower than predicted when using the CAROC tool. Over-estimation of fracture risk may influence shared decision-making discussions. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - October 6, 2022 Category: Orthopaedics Source Type: research

A model-based cost-effectiveness analysis of fracture liaison services in China
ConclusionFLS could potentially lead to lifetime cost-saving in patients who have experienced a fracture. Our study informs the potential cost-effectiveness of FLS and the knowledge gap in China; more future research incorporating Chinese-specific real-world data are needed to confirm the results of our study and to better evaluate the cost-effectiveness of FLS in China. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - October 5, 2022 Category: Orthopaedics Source Type: research

Atypical femoral fracture in a bisphosphonate-na ïve patient on denosumab for osteoporosis
ConclusionThe patient underwent intramedullary nailing of the femur and denosumab was ceased. This is only the fifth case reported of atypical femoral fracture in a bisphosphonate-na ïve patient receiving denosumab for osteoporosis. Although rare, physicians should maintain a high index of suspicion for atypical femoral fracture in a patient taking denosumab even without prior bisphosphonate exposure. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - October 1, 2022 Category: Orthopaedics Source Type: research

Impact of the COVID-19 pandemic on osteoporotic hip fractures in Chile
ConclusionDuring the COVID-19 pandemic, osteoporotic HF rates decreased, along with ED consultation and hospitalization rates due to trauma in older adults. This could be a result of mobility restrictions and a significant increase in the proportion of self-reliant older adults in the Chilean population. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 30, 2022 Category: Orthopaedics Source Type: research

Correction: Real-world effectiveness of osteoporosis treatments in Germany
(Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 27, 2022 Category: Orthopaedics Source Type: research

Geographic variation in hip fracture surgery rate, care quality and outcomes: a comparison between national registries in Ireland and Denmark
ConclusionIreland and Denmark have similar hip fracture surgery rates, but differences in care quality, surgery patterns and outcomes. High variation in THA provision and observed differences in mortality require further exploration. In Ireland, there is scope for improvement regarding early surgery, mobility, nutrition assessment and improved post-discharge follow-up. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 26, 2022 Category: Orthopaedics Source Type: research

Fracture incidence in children and adolescents 0 –19 years old in Mexico: a 12-year cross-sectional analysis
ConclusionThis is the first study in Mexico to follow the behavior of fractures in the pediatric population over 12  years. Fractures seem to be decreasing in children and adolescents. An epidemiological follow-up of childhood fractures is necessary to understand the causes of fractures to generate better prevention and treatment strategies. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 21, 2022 Category: Orthopaedics Source Type: research

Trabecular bone score in the hip: a new method to examine hip bone microarchitecture —a feasibility study
ConclusionAmong older women residing in LTC facilities, there was a moderate correlation between measures of BMD and TBS Hip at total hip, femoral neck, and greater trochanter, suggesting TBS Hip may provide complementary information to BMD . (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 20, 2022 Category: Orthopaedics Source Type: research

Effect of denosumab treatment on bone mineral density and bone turnover markers in osteoporotic patients: real-life experience 2-year follow-up
ConclusionIn our group of patients under denosumab treatment, 53% of persistence was found at 24  months and associated with improvement in BMD levels without any significant side effects except one case with urticarial reaction. Denosumab leads to improvements in BMD levels and is a well-tolerated agent in a real-life setting comparable to results of randomized controlled studies in patients with different comorbidities. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 17, 2022 Category: Orthopaedics Source Type: research

Association between metabolic syndrome and osteoporosis among adults aged 50  years and older: using the National Health Information Database in South Korea
ConclusionThis study results suggested that MetS was associated with a low occurrence of osteoporosis. In contrast, MetS was associated with a high occurrence of osteoporosis in both obese men and post-MP obese women. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 16, 2022 Category: Orthopaedics Source Type: research

Alliance for the development of the Argentinian Hip Fracture Registry
ConclusionAHFR development was based on four pillars: (1) representativeness and support, (2) solid definitions from onset, (3) committed teams, and (4) stable funding. This tool may contribute to the design of evidence-based health policies to improve patient outcomes, and we hope this experience will help other LMICs to develop their own tailored-to-their-needs registries. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 13, 2022 Category: Orthopaedics Source Type: research

Prevalent vertebral fractures among urban-dwelling Chinese postmenopausal women: a population-based, randomized-sampling, cross-sectional study
ConclusionVFs are prevalent among Chinese postmenopausal women who were  ≥ 50 years and community-dwelled. Osteoporosis prevalence is remarkable when fragile fractures were part of clinical diagnosis. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 7, 2022 Category: Orthopaedics Source Type: research

Real-world effectiveness of osteoporosis treatments in Germany
ConclusionContinued treatment with osteoporosis medications was associated with reductions of fracture rates in a real-world setting. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - August 31, 2022 Category: Orthopaedics Source Type: research

Does metabolic syndrome increase the risk of fracture? A systematic review and meta-analysis
ConclusionThis systematic review and meta-analysis showed that the current literature suggests that metabolic syndrome is a protective factor for bone fractures in males but has no net effect on fractures among females. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - August 31, 2022 Category: Orthopaedics Source Type: research

Current status and challenges in the management of osteoporosis among men in the Philippines
(Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - August 25, 2022 Category: Orthopaedics Source Type: research