Factors affecting bone mineral density in postmenopausal women
Conclusion The results of this study indicated a significant association between OP and MD, obesity, parity, MS, history of fracture, serum ferritin, level of education, and physical activity. However, the direction and the strength of association varied across BMD measurement sites. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - May 14, 2015 Category: Orthopaedics Source Type: research

Estimating osteoporotic fracture risk following a wrist fracture: a tale of two systems
Abstract Summary The WHO fracture risk assessment (FRAX) and Canadian Association of Radiologists and Osteoporosis Canada (CAROC) tools can both be used to determine an individual’s 10-year risk of osteoporotic fracture. However, these tools differ in their risk calculation. For participants
Source: Archives of Orthopaedic and Trauma Surgery - May 8, 2015 Category: Orthopaedics Source Type: research

Association and relative importance of multiple obesity measures with bone mineral density: the National Health and Nutrition Examination Survey 2005–2006
We examined the association between multiple obesity measures and BMD and determined the relative importance (RI, percentage of variation) of multiple obesity measures associated with BMD. Methods Data from 5287 men and women aged between 8 and 69 years (mean age = 29 years) in the National Health and Nutrition Examination Survey 2005–2006 were analyzed. Body mass index (BMI), waist circumference, hip circumference, body fat mass (FM) index, total body FM, abdominal FM, and appendicular FM were considered the exposures and femoral neck and lumbar spi...
Source: Archives of Orthopaedic and Trauma Surgery - May 8, 2015 Category: Orthopaedics Source Type: research

Publication outcomes of the abstracts presented at the 2011 European Congress on Osteoporosis, Osteoarthritis and Musculo-Skeletal Diseases (ECCEO-IOF11)
Abstract Summary The publication outcomes of the abstracts presented during the ECCEO-IOF 2011 reflect a high research productivity, support the robustness of the selection process conducted by the Scientific Advisory Committee and suggest that IOF-ESCEO WCO is successful in its mission to promote and disseminate research. Background and Objective The European (now World) Congress on Osteoporosis, Osteoarthritis and Musculo-Skeletal Diseases (IOF-ESCEO WCO, formerly ECCEO-IOF) is the largest worldwide event fully dedicated to the clinical, epidemi...
Source: Archives of Orthopaedic and Trauma Surgery - April 24, 2015 Category: Orthopaedics Source Type: research

Carpal and scaphoid fracture incidence in south-eastern Australia: an epidemiologic study
Conclusion Almost all fractures were the result of a fall. In males, carpal fractures were sustained mainly during early adulthood and in females during adolescence and after menopause. Incidence rates for males were higher than those in females for both scaphoid and non-scaphoid fractures. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 24, 2015 Category: Orthopaedics Source Type: research

Osteoporosis management and fractures in the Métis of Ontario, Canada
Conclusions Despite finding significantly lower rates of osteoporosis management among men, Métis men and women were found to have similar age-standardized fracture rates to the general population. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 24, 2015 Category: Orthopaedics Source Type: research

Risedronate as an intra-abdominal sepsis mimic: a case report
Discussion Despite multiple investigations, no cause was found, but the timing of the symptoms coincided with monthly risedronate administration. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 20, 2015 Category: Orthopaedics Source Type: research

Renal impairment among postmenopausal women with osteoporosis from a large health plan in Israel
Abstract Summary Bisphosphonates are a first-line treatment for osteoporosis but require adequate renal function. We estimated the prevalence of renal impairment among osteoporotic women in Israeli. Approximately 2.3 % of women had renal impairment at a level that makes them inappropriate for bisphosphonate use, demonstrating the need for alternative therapies for osteoporosis treatment. Purpose The purpose of this study is to estimate the prevalence of renal impairment among postmenopausal osteoporotic women within a...
Source: Archives of Orthopaedic and Trauma Surgery - March 10, 2015 Category: Orthopaedics Source Type: research

Comments on Korthoewer and Chandran: Osteoporosis management and the utilization of FRAX®: a survey amongst health care professionals of the Asia-Pacific
(Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 4, 2015 Category: Orthopaedics Source Type: research

Osteoporosis management and the utilization of FRAX®: a survey amongst health care professionals of the Asia-Pacific—response to comments by Lee and Ha
(Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - March 4, 2015 Category: Orthopaedics Source Type: research

Sacral insufficiency fractures: an underdiagnosed injury during childbirth?
Abstract Summary Insufficiency fractures during pregnancy or childbirth are difficult to diagnose but holds high morbidity for a vulnerable patient group. In documenting the patient’s pathway, diagnostic challenges and treatment options, it is hoped that pregnancy-related insufficiency fractures will be better diagnosed and treated. Introduction Sacral insufficiency fractures are a poorly understood phenomenon, which poses diagnostic and therapeutic challenges. Peripartum females who suffer from transient osteoporosis of pregnancy have been ...
Source: Archives of Orthopaedic and Trauma Surgery - February 24, 2015 Category: Orthopaedics Source Type: research

Lower bone mineral density in Somali women living in Sweden compared with African–Americans
Abstract Summary Vitamin D deficiency can lead to osteomalacia. Bone mineral density was lower in Somali women, living in Sweden, in relation to both the American and the African–American reference populations. The majority, 73 %, had vitamin D deficiency, and supplementation should be considered to prevent from osteomalacia, osteoporosis and future fractures. Purpose Low vitamin D can lead to osteomalacia. The hypothesis was that bone mineral density (BMD) in Somali women living in Sweden was lower in compariso...
Source: Archives of Orthopaedic and Trauma Surgery - February 19, 2015 Category: Orthopaedics Source Type: research

Factors associated with bone mineral density in healthy African women
The objective of this study was to determine the factors associated with BMD in healthy premenopausal women in Uganda and Zimbabwe. Methods Baseline total hip (TH) and lumbar spine (LS) BMD was measured by dual x-ray absorptiometry in 518 healthy, premenopausal black women enrolling in VOICE, an HIV-1 chemoprevention trial, at sites in Uganda and Zimbabwe. Contraceptive and lactation histories, physical activity assessment, calcium intake, and serum vitamin D levels were assessed. Independent factors associated with BMD were identified using an analysis of covariance model. ...
Source: Archives of Orthopaedic and Trauma Surgery - February 14, 2015 Category: Orthopaedics Source Type: research

Vertebral fracture prevalence in black and white South African women
Conclusion Our findings are noteworthy and the first attempt to compare vertebral fracture risk in women of different ethnicities on the African continent. A similar vertebral fracture risk between black and white women in South Africa must be considered at present to ensure appropriate evaluation in all subjects who present with clinical risk factors for osteoporosis, regardless of ethnicity. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - February 13, 2015 Category: Orthopaedics Source Type: research

Epidemiology of proximal humerus fractures
Conclusion The incidence of proximal humerus fractures increases with age, and we observe a seasonal variation strongly favoring winter months. It is evident that proximal humerus fractures cause considerable morbidity among elderly people and consume health care resources. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - February 13, 2015 Category: Orthopaedics Source Type: research

Age-related variation in limb bone diaphyseal structure among Inuit foragers from Point Hope, northern Alaska
Conclusions While the physically demanding lifestyles of certain traditional-living groups may protect against bone loss and fracture susceptibility, this is not the case among the Inuit. It remains possible, however, that Western characteristics of the modern Inuit lifestyle exacerbate age-related skeletal deterioration. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - December 9, 2014 Category: Orthopaedics Source Type: research

Osteoporosis knowledge, self-efficacy, and health beliefs among Chinese individuals with HIV
Conclusions Behavioral frameworks such as the HBM may provide important insight into promoting adoption and maintenance of osteoporosis-related preventive behaviors among individuals with HIV. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - December 9, 2014 Category: Orthopaedics Source Type: research

Bone fractures and feeling at risk for osteoporosis among women in Japan: patient characteristics and outcomes in the National Health and Wellness Survey
This study was conducted to explore characteristics associated with history of fractures and feeling at risk for osteoporosis in women aged 50 and older in Japan. Methods Data were provided by a large annual survey representative of Japanese aged 18 and older. Women 50 and older without diagnosed osteoporosis were categorized into four mutually exclusive groups based on fracture history since age 50 and feeling at risk for developing osteoporosis. Sociodemographic and health characteristics were compared across groups using bivariate statistics, and health outcomes were compared ...
Source: Archives of Orthopaedic and Trauma Surgery - November 12, 2014 Category: Orthopaedics Source Type: research

Current and future burden of incident hip fractures in New South Wales, Australia
Conclusion An ageing population and changing demographics will continue to drive the increasing burden of incident hip fractures in NSW and Australia in the foreseeable future. These anticipated changes provide important information for the planning and management of future hip fracture care. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - November 10, 2014 Category: Orthopaedics Source Type: research

Hospital admission rates for distal forearm fractures: an epidemiological survey in patients referred to a large emergency department in Northern Italy
Conclusions The percentage of fragility distal forearm fractures hospitalized in our area is relatively low and generally lower than that reported in other studies. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - November 4, 2014 Category: Orthopaedics Source Type: research

Are there still east-to-west differences in the incidence of hip fractures in Germany?
Conclusion The reason for such differences is still unclear and, thus, the consequences of urbanization must be considered to explain diverse incidence rates. In general, the investigation of causes should be based on the use of a multivariate model that takes additional factors such as specific drug use, socioeconomic aspects, environmental aspects, education, and health care into account. There are large regional differences in the incidence of hip fracture in Germany. These differences were unexpected and do not follow a north-to-south or an east-to-west gradient. But they are of high socioeconomic importance...
Source: Archives of Orthopaedic and Trauma Surgery - October 17, 2014 Category: Orthopaedics Source Type: research

Who are the older Australians referred for a bone density scan? Data from the Barwon region
Abstract Summary We investigated the reasons for referral of older Australians aged 70 years and older to dual energy X-ray absorptiometry (DXA). The most common clinical indication was being aged 70 years and older, followed by monitoring for fracture or low bone mineral density (BMD). Compared to males, females were twice as likely to have osteoporotic BMD. Purpose/Introduction Little is known about reasons for the referral of older Australians to dual energy X-ray absorptiometry (DXA) for bone mineral density (BMD) measurements. Thus,...
Source: Archives of Orthopaedic and Trauma Surgery - October 13, 2014 Category: Orthopaedics Source Type: research

Vitamin D response of older people in residential aged care to sunlight-derived ultraviolet radiation
Conclusions Natural UVR exposure can increase 25OHD levels in older people in residential care, but depends on the season of exposure. However, due to inadequate sun exposure, 25OHD did not reach optimal levels. Nevertheless, where sun exposure is encouraged in this group, the focus for the start of exposure should be in the months of spring or autumn, as this timing was associated with a vitamin D response. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - October 13, 2014 Category: Orthopaedics Source Type: research

Subchondral insufficiency fractures and spontaneous osteonecrosis of the knee may not be related to osteoporosis
Conclusions We conclude that osteoporosis is not the underlying cause of this disorder in the majority of patients. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - September 19, 2014 Category: Orthopaedics Source Type: research

Increasing trends and significance of hypovitaminosis D: a population-based study in the Kingdom of Saudi Arabia
Abstract Summary Vitamin D deficiency is highly prevalent in Saudi Arabia, particularly among young women and is emerging as public health threat of epidemic proportions. Prevalence of severe hypovitaminosis D is expected to rise exponentially without primary intervention. This largest study encompasses extent of vitamin D deficiency and recommendations to reduce significant health care burden. Introduction The aim of the study was to determine the prevalence and significance of vitamin D deficiency in Saudi population and to help develop national...
Source: Archives of Orthopaedic and Trauma Surgery - September 12, 2014 Category: Orthopaedics Source Type: research

Bone density in black and white South African women: contribution of ethnicity, body weight and lifestyle
Abstract Summary Ethnic differences in bone mineral density (BMD) between healthy adult black and white South African women were studied. Higher BMD was only noted at the femoral sites in black women. Body weight significantly impacted these findings. A lower fracture risk at all skeletal sites cannot be assumed in black South African (SA) women. Purpose Bone mineral density (BMD) varies amongst women of different ethnicities. African-Americans have higher BMD at all skeletal sites compared with whites. On the African cont...
Source: Archives of Orthopaedic and Trauma Surgery - September 5, 2014 Category: Orthopaedics Source Type: research

Women’s perspectives and experiences on screening for osteoporosis (Risk-stratified Osteoporosis Strategy Evaluation, ROSE)
Conclusion In general, the women accepted the screening program. No major ethical reservations or adverse psychological consequences were detected. Only a minority of women declined screening participation due to a low perceived risk of osteoporosis. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - August 19, 2014 Category: Orthopaedics Source Type: research

Impact of comorbidity, age, and gender on seasonal variation in hip fracture incidence. A NOREPOS study
Conclusions There was a distinct seasonal variation in hip fracture incidence, present in all subgroups of gender, age, or comorbidity. This variation should be accounted for when planning health-care services. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - August 19, 2014 Category: Orthopaedics Source Type: research

Effect of raloxifene hydrochloride on bone mineral density and bone turnover in Kuwaiti postmenopausal women with osteoporosis
Conclusions Raloxifene appears to be an effective, well-tolerated option for treating osteoporosis in Kuwaiti postmenopausal women, suitable for long-term use. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - July 19, 2014 Category: Orthopaedics Source Type: research

Milk fortified with vitamin D could reduce the prevalence of vitamin D deficiency among Japanese female college students
Conclusions The high prevalence of VD deficiency in Japanese female college students was decreased by consuming VD-fortified milk. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - July 3, 2014 Category: Orthopaedics Source Type: research

Assessment of lean (muscle) mass and its distribution by dual energy X-ray absorptiometry in healthy Indian females
Abstract Summary Mean appendicular lean mass increased from the second decade to reach maximum in the fourth decade in Indian women. Post-menopausal females with LMM were significantly older, leaner, and had lower bone mineral density (BMD). Lean mass and ASMI were negatively correlated with age and positively with BMI and BMD at all sites. Introduction Sarcopenia is defined by low muscle mass (LMM), strength, and performance. Lean mass can be precisely measured by dual-energy X-ray absorptiometry (DXA). There is no uniform definition of LMM. We u...
Source: Archives of Orthopaedic and Trauma Surgery - July 1, 2014 Category: Orthopaedics Source Type: research

Epidemiology and economic burden of osteoporosis in Switzerland
Conclusions In spite of the high cost of osteoporosis, a substantial treatment gap and projected increase of the economic burden driven by an aging population, the use of pharmacological prevention of osteoporosis is significantly less than optimal, suggesting that a change in health care policy concerning the disease is warranted. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - June 27, 2014 Category: Orthopaedics Source Type: research

The Tromsø Study: Fit Futures : a study of Norwegian adolescents’ lifestyle and bone health
Abstract Summary Bone mass achievement predicts later fracture risk. This population-based study describes bone mineral density (BMD) levels and associated factors in Norwegian adolescents. Compared with international reference ranges, BMD levels appear higher and physical activity levels are positively associated with BMD. Purpose Norway has one of the highest reported incidences of osteoporotic fractures. Maximisation of peak bone mass may prevent later fractures. This population-based study compared BMD levels of Norweg...
Source: Archives of Orthopaedic and Trauma Surgery - June 4, 2014 Category: Orthopaedics Source Type: research

The Tromsø Study: Fit Futures: a study of Norwegian adolescents’ lifestyle and bone health
Abstract Summary Bone mass achievement predicts later fracture risk. This population-based study describes bone mineral density (BMD) levels and associated factors in Norwegian adolescents. Compared with international reference ranges, BMD levels appear higher and physical activity levels are positively associated with BMD. Purpose Norway has one of the highest reported incidences of osteoporotic fractures. Maximisation of peak bone mass may prevent later fractures. This population-based study compared BMD levels of Norweg...
Source: Archives of Orthopaedic and Trauma Surgery - June 4, 2014 Category: Orthopaedics Source Type: research

Bone microarchitecture and strength of the radius and tibia in a reference population of young adults: an HR-pQCT study
Abstract Summary Within a normative youth cohort (16–29 years) bone parameters for males and females remained stable at the radius. At the tibia, a peak was observed for females at 16–19 years, with bone density and strength decreasing by 29 years. Purpose To determine if bone microstructural and strength parameters identified by high-resolution peripheral quantitative computed tomography (HR-pQCT) and finite element analysis (FEA) at the distal radius and tibia, peak within the age range of this youth cohort, and whethe...
Source: Archives of Orthopaedic and Trauma Surgery - May 27, 2014 Category: Orthopaedics Source Type: research

Risk factors of low vitamin D status in adolescent females in Kuwait: implications for high peak bone mass attainment
Abstract Summary Risks of low vitamin D status in Kuwaiti adolescent girls are high parathyroid hormone (PTH), high waist/hip ratio, veiling and not having a private room. Low vitamin D status is likely to have a negative impact on their bone mass and accrual. Introduction Low serum 25-hydroxyvitamin D (25OHD) levels are repeatedly found in females in the Middle East, which is a cause for concern particularly for adolescent females. This is because vitamin D has been shown to promote bone mineral accrual in adolescence. ...
Source: Archives of Orthopaedic and Trauma Surgery - May 24, 2014 Category: Orthopaedics Source Type: research

Estimating prevalence of osteoporosis: examples from industrialized countries
Conclusions Up to 49 million individuals met the WHO osteoporosis criteria in a number of industrialized countries in North America, Europe, Japan, and Australia. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - May 16, 2014 Category: Orthopaedics Source Type: research

Osteomalacia in Crohn’s disease
Conclusions Osteomalacia should be considered in differential diagnosis when assessing low back pain in the patients with chronic inflammatory bowel disease. Vitamin D deficiency should be treated with vitamin D supplementation in patients with Crohn's disease to prevent osteomalacia. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - May 14, 2014 Category: Orthopaedics Source Type: research

Comparison of peripheral forearm DXA and clinical risk factor screening using FRAX® to assess the risk of HIV-associated low bone mass: a cross-sectional study
Abstract Summary There is growing awareness that HIV infection is associated with low bone mass and fracture. DXA is a relatively scarce resource. Therefore, we evaluated two tools: peripheral DXA (pDXA) at the forearm and Fracture Risk Assessment Tool (FRAX®) to see which performed best at identifying men who should undergo DXA. In this setting, neither pDXA nor FRAX® showed good sensitivity and specificity for DXA. Purpose Infection with human immunodeficiency virus (HIV) is associated with an increased risk of l...
Source: Archives of Orthopaedic and Trauma Surgery - May 14, 2014 Category: Orthopaedics Source Type: research

Gender disparity in BMD conversion: a comparison between Lunar and Hologic densitometers
This study of 110 male subjects scanned on Hologic and Lunar densitometers demonstrates that published equations may not applicable to men at the lumbar spine. Male inter-conversion equations have also been derived. Purpose Currently, available equations for inter-manufacturer conversion of bone mineral density (BMD) and calculation of standardised BMD (sBMD) are used in both males and females, despite being derived and validated only in women. Our aim was to test the validity of the published equations in men. ...
Source: Archives of Orthopaedic and Trauma Surgery - May 8, 2014 Category: Orthopaedics Source Type: research

Weekly teriparatide administration for the treatment of delayed union: a report of two cases
Conclusion Weekly teriparatide administration was effective for bone healing and useful for delayed union; moreover, the effect of this therapy showed within 4 weeks. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 29, 2014 Category: Orthopaedics Source Type: research

Relationship between 25-hydroxyvitamin D concentrations, serum calcium, and parathyroid hormone in apparently healthy Syrian people
Abstract Summary Vitamin D deficiency (25-hydroxyvitamin D (25OHD)
Source: Archives of Orthopaedic and Trauma Surgery - April 9, 2014 Category: Orthopaedics Source Type: research

Body mass index is positively associated with bone mineral density in US older adults
The objective of this study was to examine the association between body mass index (BMI) and bone mineral density (BMD) in a recent, nationally representative sample of US older adults as well as to see if this relationship differs by age, sex, and race. Methods Data for this study were obtained from the National Health and Nutrition Examination Survey (2005–2008) for adults ages 50 and older (n = 3,296). Linear regression models were used to predict BMD of the femoral neck (measured by dual-energy X-ray absorptiometry (DXA)) as a function of BMI (measured hei...
Source: Archives of Orthopaedic and Trauma Surgery - March 25, 2014 Category: Orthopaedics Source Type: research

Relation between BMD and biochemical, transfusion and endocrinological parameters in pediatric thalassemic patients
Abstract Summary Low BMDs, short stature, hypogonadism, subclinical hypothyroidism, and IFG are found in 3.3, 10, 33, 16.6, 6.6, and 26.6 % of 30 pediatric β thalassemia major patients, respectively. Age is related with low Z-scores. Short stature and hypogonadism patients were older. These patients’ monitoring in late childhood and early teenage for these complications is recommended. Background Beta-thalassemia major patients frequently have low BMD and increased fracture risk. We tried to determine the relation between BMD and b...
Source: Archives of Orthopaedic and Trauma Surgery - March 21, 2014 Category: Orthopaedics Source Type: research