Inflammation in the Prediction of Type 2 Diabetes and Hypertension in Healthy Adults
While inflammation is associated with obesity and insulin resistance, their inter-relationships in the development of type 2 diabetes or hypertension are not clear. (Source: Archives of Medical Research)
Source: Archives of Medical Research - December 5, 2017 Category: Research Authors: Ki-chul Sung, Seungho Ryu, Joo-wook Sung, Yong Bum Kim, Yu Sam Won, Dong Sik Cho, Sun H. Kim, Alice Liu Tags: Original Article Source Type: research

Donor Polymorphisms of Toll-like Receptor 4 rs1927914 Associated with the Risk of Hepatocellular Carcinoma Recurrence Following Liver Transplantation
Hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) severely restricts the long-term survival of patients. Toll-like receptor 4 (TLR4) has been considered to be involved in hepatocarcinogenesis and metastasis. Additionally, there is a study demonstrating the significant association between TLR4 gene rs1927914 polymorphism and HCC, but no study investigated the association of the TLR4 rs1927914 polymorphism with the risk of HCC recurrence following LT. (Source: Archives of Medical Research)
Source: Archives of Medical Research - December 5, 2017 Category: Research Authors: Guangjun Shi, Chuanxu Wang, Ping Zhang, Lisha Ji, Shifeng Xu, Xueying Tan, Hao Li Tags: Preliminary Report Source Type: research

Optimizing Non-Pharmacologic Management of Hypertriglyceridemia
The cornerstone of initial management for hypertriglyceridemia (HTG) is lifestyle modification. The combination of weight loss through caloric restriction, alteration in macronutrient composition and increased energy expenditure reduces TG levels by approximately 50%. The addition of cinnamon, cacao products and isocaloric substitution of 1 serving of nuts may contribute another 5 –15% lowering of TG. This can be particularly beneficial in patients with HTG who are at increased risk of cardiovascular disease. (Source: Archives of Medical Research)
Source: Archives of Medical Research - December 5, 2017 Category: Research Authors: Alexandra Byrne, Sunal Makadia, Aimee Sutherland, Michael Miller Tags: Review Article Source Type: research

On the Search to Elucidate the Role of Microbiota in the Genesis of Cancer: The Cases of Gastrointestinal and Cervical Cancer
The microbiota that inhabits the human body plays an important role in health and disease, by their fundamental role in food digestion, training of the immune system or protection against pathogen colonization. However, when the equilibrium with its host is altered, some diseases like cancer might be promoted. In this review we describe the information collected in recent studies between the microbiota and its association with cancer. We conducted the review of the relation of microbiome and cancer etiology focusing on the gastrointestinal and cervical cancer. (Source: Archives of Medical Research)
Source: Archives of Medical Research - December 1, 2017 Category: Research Authors: Francisco Avil és-Jiménez, Yu Guoqin, Kirvis Torres-Poveda, Vicente Madrid-Marina, Javier Torres Tags: Review Article Source Type: research

On the Search to Elucidate the Role of the Microbiota in the Genesis of Cancer: The Cases of Gastrointestinal and Cervical Cancer
The microbiota that inhabits the human body plays an important role in health and disease, by their fundamental role in food digestion, training of the immune system or protection against pathogen colonization. However, when the equilibrium with its host is altered, some diseases like cancer might be promoted. In this review we describe the information collected in recent studies between the microbiota and its association with cancer. We conducted the review of the relation of microbiome and cancer etiology focusing on the gastrointestinal and cervical cancer. (Source: Archives of Medical Research)
Source: Archives of Medical Research - December 1, 2017 Category: Research Authors: Francisco Avil és-Jiménez, Yu Guogin, Kirvis Torres-Poveda, Vicente Madrid-Marina, Javier Torres Tags: Review Article Source Type: research

Insulin-like Growth Factor 1 Mediates Adrenal Development Dysfunction in Offspring Rats Induced by Prenatal Food Restriction
Our previous study demonstrated that prenatal food restriction (PFR) could induce the dysfunction of the hypothalamic –pituitary–adrenal axis and glucocorticoid-related glucose and lipid metabolic alterations in adult offspring rats. (Source: Archives of Medical Research)
Source: Archives of Medical Research - December 1, 2017 Category: Research Authors: Zheng He, Feng Lv, Yufeng Ding, Chunyan Zhu, Hegui Huang, Li Zhang, Yu Guo, Hui Wang Tags: Original Article Source Type: research

Development of Microbiota in Infants and its Role in Maturation of Gut Mucosa and Immune System
Dysbiosis of the gut microbiota has been associated with increasing numbers of diseases, including obesity, diabetes, inflammatory bowel disease, asthma, allergy, cancer and even neurologic or behavioral disorders. The other side of the coin is that a healthy microbiota leads to a healthy human development, to a mature and well trained immune system and to an efficient metabolic machinery. What we have learned in adults is in the end the result of a good start, a programmed, healthy development of the microbiota that must occur in the early years of life, probably even starting during the fetal stage. (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 30, 2017 Category: Research Authors: Cecilia Ximenez, Javier Torres Tags: Review Article Source Type: research

Development of the Microbiota in Infants and its Role in Maturation of the Gut Mucosa and the Immune System
Dysbiosis of the gut microbiota has been associated with increasing numbers of diseases, including obesity, diabetes, inflammatory bowel disease, asthma, allergy, cancer and even neurologic or behavioral disorders. The other side of the coin is that a healthy microbiota leads to a healthy human development, to a mature and well trained immune system and to an efficient metabolic machinery. What we have learned in adults is in the end the result of a good start, a programmed, healthy development of the microbiota that must occur in the early years of life, probably even starting during the fetal stage. (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 30, 2017 Category: Research Authors: Cecilia Ximenez, Javier Torres Tags: Reviewer Article Source Type: research

Lipoamide Inhibits NF1 Deficiency-induced Epithelial-Mesenchymal Transition in Murine Schwann Cells
This study was designed to investigate whether excessive ROS conferred to Nf1 deficiency-induced EMT in Schwann cells. (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 29, 2017 Category: Research Authors: Yuchen Zhang, Rongsheng Zhou, Yiping Qu, Maoguo Shu, Shuzhong Guo, Zhuanli Bai Tags: Original Article Source Type: research

Contemporary Applications of Fecal Microbiota Transplantation to Treat Intestinal Diseases in Humans
The intestinal microbiota comprise an important organ that plays a vital role in host digestion, development, energy maintenance, hemostasis, and immunity. Disruption of the gut microbial community due to diet, lifestyle, or antibiotic exposure increases susceptibility to chronic infection and disease. Fecal microbiota transplantation (FMT) involves the transfer of gut microbiota from a healthy donor to a patient in order to restore normal diversity and function of the microbial community. This method has become a well established alternative therapy for the treatment of recurrent Clostridium difficile infection. (Source: ...
Source: Archives of Medical Research - November 25, 2017 Category: Research Authors: Christopher Staley, Alexander Khoruts, Michael J. Sadowsky Tags: Review Article Source Type: research

Maternal Micronutrients, Omega-3 Fatty Acids and Gene Expression of Angiogenic and Inflammatory Markers in Pregnancy Induced Hypertension Rats
Preeclampsia is a disorder of pregnancy and is associated with inflammation and altered angiogenesis. The present study examines the effect of micronutrient and omega-3 fatty acid supplementation (individual, as well as combined) on genes involved in inflammation and angiogenesis, as well as global DNA methylation levels in a pregnancy induced hypertension (PIH) rat model. (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 10, 2017 Category: Research Authors: Nisha Kemse, Deepali Sundrani, Anvita Kale, Sadhana Joshi Tags: Original Article Source Type: research

Effect of Native and Minimally Modified Low-density Lipoprotein on the Activation of Monocyte Subsets
The objective of this research was to determine the number of monocyte subsets positives to cytokines in response to native (nLDL) and minimally modified LDL (mmLDL). (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 10, 2017 Category: Research Authors: Francisco Blanco-Favela, Jos é Esteban Espinosa-Luna, Adriana Karina Chávez-Rueda, Alejandra Madrid-Miller, Luis Chávez-Sánchez Tags: Original Article Source Type: research