Effects of Melatonin on Blood Pressure, Oxidative Stress and Placental Expressions of TNF α, IL-6, VEGF and sFlt-1 in RUPP Rat Model of Preeclampsia
Preeclampsia (PE) is known as a major cause of maternal and neonatal morbidity and mortality. Maternal hypertension, proteinuria, placental dysfunction and imbalance of angiogenic factors can be observed in PE (1). The reduction in uteroplacental perfusion can cause ischemia and the ischemic placenta releases soluble factors causing maternal endothelial dysfunction and hypertension (2). These alterations also lead to an increased production of proinflammatory cytokines such as tumor necrosis factor alpha (TNF- α) and IL-6 from the placenta (3). (Source: Archives of Medical Research)
Source: Archives of Medical Research - February 4, 2018 Category: Research Authors: Metehan Uzun, Meryem Gencer, Hakan Turkon, Rahime Ozlem Oztopuz, Ufuk Demir, Mehmet Akif Ovali Tags: Original Article Source Type: research

20 Years Spatial-Temporal Analysis of Dengue Fever and Hemorrhagic Fever  in Mexico
Dengue Fever (DF) is a human vector-borne disease and a major public health problem worldwide. In Mexico, DF and Dengue Hemorrhagic Fever (DHF) cases have increased in recent years. The aim of this study was to identify variations in the spatial distribution of DF and DHF cases over time using space-time statistical analysis and geographic information systems. (Source: Archives of Medical Research)
Source: Archives of Medical Research - February 2, 2018 Category: Research Authors: Sendy Isarel Hern ández-Gaytán, Francisco Javier Díaz-Vásquez, Luis Gerardo Duran-Arenas, Malaquías López Cervantes, Stephen J. Rothenberg Tags: Original Article Source Type: research

Spatial-Temporal Analysis of Dengue Fever and Hemorrhagic Fever in Mexico from 1995 –2015
Dengue Fever (DF) is a human vector-borne disease and a major public health problem worldwide. In Mexico, DF and Dengue Hemorrhagic Fever (DHF) cases have increased in recent years. The aim of this study was to identify variations in the spatial distribution of DF and DHF cases over time using space-time statistical analysis and geographic information systems. (Source: Archives of Medical Research)
Source: Archives of Medical Research - February 2, 2018 Category: Research Authors: Sendy Isarel Hern ández-Gaytán, Francisco Javier Díaz-Vásquez, Luis Gerardo Duran-Arenas, Malaquías López Cervantes, Stephen J. Rothenberg Tags: Original Article Source Type: research

Human Virome
The human virome is composed by the set of all viruses, eukaryotic and prokaryotic, present in the human body; as each body compartment constitutes a different microenvironment, the virome varies with the body part. Additionally, other factors influence the virome composition, such as age, diet, and the presence of other components of the microbiome. The study of the virome takes advantage of the development of next generation sequencing, and has allowed the discovery of novel viruses, and the characterization of the virome in healthy and diseased individuals, allowing the association of viruses with specific diseases. (So...
Source: Archives of Medical Research - February 1, 2018 Category: Research Authors: Selene Z árate, Blanca Taboada, Martha Yocupicio-Monroy, Carlos F. Arias Tags: Review Article Source Type: research

The Human Virome
The human virome is composed by the set of all viruses, eukaryotic and prokaryotic, present in the human body; as each body compartment constitutes a different microenvironment, the virome varies with the body part. Additionally, other factors influence the virome composition, such as age, diet, and the presence of other components of the microbiome. The study of the virome takes advantage of the development of next generation sequencing, and has allowed the discovery of novel viruses, and the characterization of the virome in healthy and diseased individuals, allowing the association of viruses with specific diseases. (So...
Source: Archives of Medical Research - February 1, 2018 Category: Research Authors: Selene Z árate, Blanca Taboada, Martha Yocupicio-Monroy, Carlos F. Arias Tags: Review Article Source Type: research

Evolving Ecosystems: Inheritance and Selection in the Light of the Microbiome
The importance of microorganisms in human biology is undeniable. The amount of research that supports that microbes have a fundamental role in animal and plant physiology is substantial and increasing every year. Even though we are only beginning to comprehend the broadness and complexity of microbial communities, evolutionary theories need to be recast in the light of such discoveries to fully understand and incorporate the role of microbes in our evolution. Fundamental evolutionary concepts such as diversity, heredity, selection, speciation, etc., which constitute the modern synthesis, are now being challenged, or at lea...
Source: Archives of Medical Research - January 22, 2018 Category: Research Authors: Santiago Sandoval-Motta, Maximino Aldana, Alejandro Frank Tags: Review Article Source Type: research

Editorial Board
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2018 Category: Research Source Type: research

Table of Contents
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2018 Category: Research Source Type: research

Author Index-Volume 48
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2018 Category: Research Source Type: research

Subject Index-Volume 48
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2018 Category: Research Source Type: research

Instructions for Authors
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2018 Category: Research Source Type: research

Gut Microbiota in Obesity and Metabolic Abnormalities: A Matter of Composition or Functionality?
The obesity pandemic and the metabolic complications derived from it represent a major public health challenge worldwide. Although obesity is a multifactorial disease, research from the past decade suggests that the gut microbiota interacts with host genetics and diet, as well as with other environmental factors, and thus contributes to the development of obesity and related complications. Despite abundant research on animal models, substantial evidence from humans has only started to accumulate over the past few years. (Source: Archives of Medical Research)
Source: Archives of Medical Research - December 29, 2017 Category: Research Authors: Sofia Moran-Ramos, Blanca E. L ópez-Contreras, Samuel Canizales-Quinteros Tags: Review Article Source Type: research