Effects of miR-29a and miR-101a Expression on Myocardial Interstitial Collagen Generation After Aerobic Exercise in Myocardial-infarcted Rats
Myocardial infarction (MI) is accompanied by increased collagen deposition, cell necrosis and angiogenesis in cardiac tissue, which results in reduced ventricular compliance. Both microRNA-29a (miR-29a) and microRNA-101a (miR-101a) target the mRNAs encoding collagens and other proteins involved in fibrosis. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Li Xiao, Huimin He, Lele Ma, Miaomiao Da, Sinan Cheng, Yan Duan, Qian Wang, Huayi Wu, Xigui Song, Wei Duan, Zhenjun Tian, Yingchun Hou Tags: Original Article Source Type: research
Increased Circulating Autoantibodies Levels of IgG, IgA, IgM Against Cytokeratin 18 and Cytokeratin 19 in Chronic Obstructive Pulmonary Disease
Autoimmune processes are involved in the progression of chronic obstructive pulmonary disease (COPD). Autoantibodies against cytokeratin 18 (CK18) and cytokeratin 19 (CK19) could be associated with lung injury. We undertook this study to investigate the role of these autoantibodies against CK18 and CK19 in the development of COPD. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Yin Xiong, Sihai Gao, Guangwei Luo, Guilian Cheng, Wei Huang, Rui Jiang, Yueqin Wang, Tianpen Cui Tags: Original Article Source Type: research
Loperamide-induced Cardiac Depression Is Enhanced by Hyperglycemia: Evidence Relevant to Loperamide Abuse
Cardiac dysryhthmias and death are reported after loperamide abuse. The mechanism of death is not clear and cardiac depression may play a role in this mechanism. Loperamide is widely used as an agonist of the μ-opioid receptor (MOR) in clinical practice. In skeletal muscle, an increase in MOR in response to hyperglycemia is largely attributable to higher expression of the transducer and activator of transcription 3 (STAT3), which binds to the promoter of the MOR genes. Therefore, we investigated the cha nges in cardiac MOR caused by hyperglycemia both in vivo and in vitro. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Shih-Hsiang Lo, Ho-Shan Niu, Yung-Ze Cheng, Chiang-Shan Niu, Juei-Tang Cheng, Po-Ming Ku Tags: Original Article Source Type: research
Polyunsaturated Fatty Acids Differentially Modulate Cell Proliferation and Endocannabinoid System in Two Human Cancer Lines
Evidence suggests that quantity and quality of dietary polyunsaturated fatty acids (PUFAs) play a role in the development of cancer. However, the mechanisms involved in this interaction(s) are not clear. Endocannabinoids are lipid metabolites known to have growth modulatory actions. We studied the effect of supplementation with PUFAs ω-6 and ω-3 (essential fatty acids, EFAs), saturated and monounsaturated fatty acids (non-EFAs) on the growth of tumor cells and modifications in their endocannabinoid content. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Repossi Gast ón, Pasqualini María Eugenia, Undurti N. Das, Aldo R. Eynard Tags: Original Article Source Type: research
Mitochondria As the Target for the Modulatory Effect of Curcumin in Oxaliplatin-induced Toxicity in Isolated Rat Liver Mitochondria
To explore hepatoprotective action of curcumin (CMN, a bioflavonoid) on oxaliplatin (Oxa)-triggered mitochondrial oxidative stress and respiratory chain complexes in liver of rats. Oxa is a ubiquitously utilized platinum-based chemotherapeutic agent commonly used for the treatment of colorectal cancer. Mitochondria have recently emerged as targets for anticancer drugs in several kinds of toxicity including hepatotoxicity that can lead to neoplastic disease. There is a dearth of evidence involving the role of mitochondria in mediating Oxa-evoked hepatotoxicity and its underlying mechanism is still debatable. (Source: Archiv...
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Mohammad Waseem, Suhel Parvez, Heena Tabassum Tags: Original Article Source Type: research
Multimorbidity Patterns in Older Adults: An Approach to the Complex Interrelationships Among Chronic Diseases
There is a growing need for evidence based answers to multimorbidity, especially in primary care settings. The aim was estimate the prevalence and patterns of multimorbidity in a Mexican population of public health institution users ≥60 years old. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Dolores Mino-Le ón, Hortensia Reyes-Morales, Svetlana V. Doubova, Ricardo Pérez-Cuevas, Liliana Giraldo-Rodríguez, Marcela Agudelo-Botero Tags: Original Article Source Type: research
Cigarette Smoking, Alcohol Consumption and Overweight in Multiple Sclerosis: Disability Progression
The rate at which disability progresses in multiple sclerosis (MS), and its severity, have been associated with modifiable lifestyle habits. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Wayra Citlali Paz-Ballesteros, Eric Alejandro Monterrubio-Flores, Jos é de Jesús Flores-Rivera, Teresa Corona-Vázquez, Carlos Hernández-Girón Tags: Original Article Source Type: research
RAS Genetic Variants in Interaction with ACE Inhibitors Drugs Influences Essential Hypertension Control
Essential Hypertension (EH) is a common disorder associated with increased cardiovascular morbidity and mortality in Malaysia. To investigate how genetic polymorphisms of the renin-angiotensin-aldosterone system (RAS) influence EH control with angiotensin-converting enzyme inhibitor drugs (ACEI). (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Farzad Heidari, Ramachandran Vasudevan, Siti Zubaidah Mohd Ali, Patimah Ismail, Mohammad Arkani Tags: Original Article Source Type: research
Circulating miR-150, miR-192, miR-200b, and miR-423-3p as Non-invasive Biomarkers of Chronic Allograft Dysfunction
Chronic allograft dysfunction (CAD) is the major cause of renal allograft loss and can only be diagnosed by invasive histological examinations. The current study aimed to determine whether or not the circulating miR-125a, miR-150, miR-192, miR-200b, miR-423-3p and miR-433 could serve as predictors of graft outcome in the renal transplant recipients with CAD. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Sepideh Zununi Vahed, Ahmad Poursadegh Zonouzi, Fariba Mahmoodpoor, Nasser Samadi, Mohammadreza Ardalan, Yadollah Omidi Tags: Original Article Source Type: research
Atherosclerosis and Cancer; A Resemblance with Far-reaching Implications
Atherosclerosis and cancer are chronic diseases considered two of the main causes of death all over the world. Taking into account that both diseases are multifactorial, they share not only several important molecular pathways but also many ethiological and mechanistical processes from the very early stages of development up to the advanced forms in both pathologies. Factors involved in their progression comprise genetic alterations, inflammatory processes, uncontrolled cell proliferation and oxidative stress, as the most important ones. (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Authors: Juana Virginia Tapia-Vieyra, Blanca Delgado-Coello, Jaime Mas-Oliva Tags: Review Article Source Type: research
Editorial Board
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Source Type: research
Table of Contents
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Source Type: research
Instructions for Authors
(Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Source Type: research
Author Index –Volume 47
Abdel-Latif, M.M.M., 340 –348 (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Source Type: research
Subject Index –Volume 47
AAA+ nuclear coregulatory cancer associated (ANCCA), in squamous cell lung carcinoma patients, clinical and prognostic significance of, 89 –95 (Source: Archives of Medical Research)
Source: Archives of Medical Research - January 1, 2017 Category: Research Source Type: research
