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The impact of 48  h high carbohydrate diets with high and low FODMAP content on gastrointestinal status and symptoms in response to endurance exercise, and subsequent endurance performance
This study investigated the effects of a high carbohydrate diet, with varied fermentable oligo-, di-, and mono-saccharide and polyol (FODMAP) content, before endurance exercise on gastrointestinal integrity, motility, and symptoms; and subsequent exercise performance. Twelve endurance athletes were provided with a 48  h high carbohydrate (mean ± SD: 12.1 ± 1.8 g kg day−1) diet on two separate occasions, composed of high (54.8 ± 10.5 g day−1) and low FODMAP (3.0 ± 0.2 g day−1) content. Thereafter, participants completed a 2 h steady-state running exercise at 60% of [math] (22.9  ± 1.2 ...
Source: Applied Physiology, Nutrition, and Metabolism - February 15, 2024 Category: Physiology Authors: Rachel Scrivin Gary Slater Alice Mika Christopher Rauch Pascale Young Isabel Martinez Ricardo J.S. Costa Source Type: research

Prospective evaluation and follow-up of nutritional status of children hospitalized in secondary-care level hospitals: a multicentre study
In conclusion, post-discharge nutritional status of children with undernutrition and/or high nutritional risk on admission to secondary-care level pediatric wards showed significant improvement, but about one-third remained undernourished. Findings warrant the need for a tailore d post-discharge nutritional follow-up. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - February 15, 2024 Category: Physiology Authors: Jessie M. Hulst Kelly van der Vorst Joanne F. Olieman Dani ëlle M. Hendriks Johanna H. Oudshoorn Frans B. Pl ötz Mari ëlle Roskam Sophie R.D. van der Schoor Gerdien A. Tramper-Stranders Jennifer J. Verhoeven Herbert M. van Wering Eefje Winder Koen F.M. Source Type: research

The impact of 48  h high carbohydratste diets with high and low FODMAP content on gastrointestinal status and symptoms in response to endurance exercise, and subsequent endurance performance
This study investigated the effects of a high carbohydrate diet, with varied fermentable oligo-, di-, and mono-saccharide and polyol (FODMAP) content, before endurance exercise on gastrointestinal integrity, motility, and symptoms; and subsequent exercise performance. Twelve endurance athletes were provided with a 48  h high carbohydrate (mean ± SD: 12.1 ± 1.8 g kg day−1) diet on two separate occasions, composed of high (54.8 ± 10.5 g day−1) and low FODMAP (3.0 ± 0.2 g day−1) content. Thereafter, participants completed a 2 h steady-state running exercise at 60% of [math] (22.9  ± 1.2 ...
Source: Applied Physiology, Nutrition, and Metabolism - February 15, 2024 Category: Physiology Authors: Rachel Scrivin Gary Slater Alice Mika Christopher Rauch Pascale Young Isabel Martinez Ricardo J.S. Costa Source Type: research

Association between macro- and microvascular damage and sarcopenia index in individuals with type 2 diabetes mellitus
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Sarcopenia was recently reported to be relevant to an increased macro-and microvascular disease risk. Sarcopenia index (SI) has been identified as a surrogate marker for sarcopenia. The aim of the present study was to investigate the association between macro- and microvascular disease and SI in patients with type 2 diabetes mellitus (T2DM). A total of 783 patients with T2DM were enrolled in this cross-sectional study. The SI was calculated by (serum creatinine [mg/dL]/cystatin C [mg/L])  × 100. The subjects were divided into three groups according to SI ter...
Source: Applied Physiology, Nutrition, and Metabolism - February 12, 2024 Category: Physiology Authors: Hui Xu Qun-Yan Xiang Jun-Kun Zhan Yi Wang Yan-Jiao Wang Shuang Li You-Shuo Liu Source Type: research

Early life exposure to Chinese famine and risk of digestive system cancer in midlife
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. To investigate whether early-life exposure to the Great Famine of 1959 –1961 in China was associated with the risk of digestive system cancer. The prospective cohort study involved 17 997 participants from the Kailuan Study (Tangshan, China) that began in 2006. All participants were divided into three groups based on their date of birth. The unexposed group (born f rom 1 October 1962 to 30 September 1964), fetal-exposed group (born from 1 October 1959 to 30 December 1961), and early-childhood-exposed group (born from 1 October 1956 to 30 December 1958). The...
Source: Applied Physiology, Nutrition, and Metabolism - February 12, 2024 Category: Physiology Authors: Yizhen Tan Xiaozhong Jiang Xiong Ding Zhihao Wei Zongshuang Song Shuohua Chen Peng Yang Dandan Zhao Shouling Wu Yun Li Source Type: research

Nutritional physiology and body composition changes during a rapid ascent to high altitude
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Exposure to high altitude might cause the body to adapt with negative energy and fluid balance that compromise body composition and physical performance. In this field study involving 12 healthy adults, sex-balanced, and aged 29  ± 4 years with a body mass index of 21.6 ± 1.8 kg/m2, we investigated the effects of a 4-day trekking up to 4556 m a.s.l. on Monte Rosa (Alps, Italy). The food intake was recorded using food diaries and nutrient averages were calculated. The bio-impedance analysis was performed at low and h igh altitudes, and a wearable biosens...
Source: Applied Physiology, Nutrition, and Metabolism - February 6, 2024 Category: Physiology Authors: Carmen Santangelo Vittore Verratti Simona Mrakic-Sposta Federica Ciampini Sofia Bonan Pamela Pignatelli Tiziana Pietrangelo Serena Pilato Samanta Moffa Antonella Fontana Raffaela Piccinelli Cinzia Le Donne Lucio Lobefalo Matteo Beccatelli Pierluigi Lodi R Source Type: research

Development of the Pediatric Integrated Nutrition Pathway for Acute Care (P-INPAC) using a modified Delphi technique
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. One in three hospitalized children have disease-related malnutrition (DRM) upon admission to hospital, and all children are at risk for further nutritional deterioration during hospital stay; however, systematic approaches to detect DRM in Canada are lacking. To standardise and improve hospital care, the multidisciplinary pediatric working group of the Canadian Malnutrition Taskforce aimed to develop a pediatric, inpatient nutritional care pathway based on available evidence, feasibility of resources, and expert consensus. The working group (n  = 13) undertoo...
Source: Applied Physiology, Nutrition, and Metabolism - February 6, 2024 Category: Physiology Authors: Kim Brunet-Wood Zujaja Tul-Noor Robert H.J. Bandsma Laura Carter Bonnie Fleming-Carroll Leah Gramlich Kim Hutchison Koen Huysentruyt Daina Kalnins Valerie Marchand Andrea Martinez Nikhil Pai M élanie Vachon Jessie M. Hulst Source Type: research

Women in Canada are consuming above the upper intake level of folic acid but few are meeting dietary choline recommendations in the second trimester of pregnancy: data from the CHILD cohort study
The objective of this study was to determine folic acid supplement use and dietary folate intakes in the second trimester (week 18) of pregnancy in women (n = 2996) in the Canadian CHILD cohort study. Vitamin B1 2 and choline intakes were also assessed because they are metabolically related to folate. The majority of participants (71.6%) were consuming a daily prenatal supplement. Twenty-eight percent of women (n = 847) reported consuming a folic acid supplement and of these women, 45.3% had daily supplem ental folic acid intakes above the upper intake level (UL; 1000 µg/day). Daily dietary folate intakes were (mean (...
Source: Applied Physiology, Nutrition, and Metabolism - February 6, 2024 Category: Physiology Authors: Alejandra M. Wiedeman Kozeta Miliku Theo J. Moraes Piushkumar J. Mandhane Elinor Simons Padmaja Subbarao Stuart E. Turvey Jill G. Zwicker Angela M. Devlin Source Type: research

A scoping review of Indigenous community-specific physical activity measures developed with and for Indigenous Peoples in Canada, Australia, and New Zealand
The objectives of this scoping review were to examine: (1) How PA research with Indigenous Peoples used community-specific PA measures developed with and/or for Indigenous Peoples in Canada, Australia, and New Zealand; and (2) How the studies util ized community-based participatory research (CBPR) principles to engage communities. A systematic search was conducted in four electronic databases (Web of Science, Medline, University of Saskatchewan Indigenous Portal, and ProQuest Dissertations and Theses Global). Thirty-one (n = 31) articles we re identified and data extracted for narrative synthesis. Studies using community...
Source: Applied Physiology, Nutrition, and Metabolism - February 6, 2024 Category: Physiology Authors: Shara R. Johnson Phil Chilibeck Sarah N. Oosman Heather J.A. Foulds Source Type: research

What ’s the big IDEA? Incorporating inclusion, diversity, equity, and access (IDEA) in population health nutrition research and practice
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Historically, the constructs of inclusion, diversity, equity, and access (IDEA) have not been sufficiently considered or included in population health nutrition research and practice. Consequently, current nutrition assessment benchmarks and knowledge translation tools may not accurately or adequately reflect diversity in the Canadian population or produce meaningful dietary guidance. The purpose of this current opinion paper is to introduce the population health nutrition research and practice framework and explore the current application of IDEA within this f...
Source: Applied Physiology, Nutrition, and Metabolism - February 6, 2024 Category: Physiology Authors: Maria Baranowski Nikki Webb Joyce Slater Source Type: research

Repeated short cold-water immersions are sufficient to habituate to the cold, but do not lead to adaptations during exercise in normobaric hypoxia
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. We sought to assess the effects of repeated cold-water immersions (CWI) on respiratory, metabolic, and sympathoadrenal responses to graded exercise in hypoxia. Sixteen (2 female) participants (age: 21.2 ±   1.3 years; body fat: 12.3 ± 7.7%; body surface area 1.87 ± 0.16 m2, VO2peak: 48.7 ± 7.9 mL/kg/min) underwent 6 CWI in 12.0 ± 1.2 °C. Each CWI was 5 min, twice daily, separated by ≥4 h, for three consecutive days, during which metabolic data were collected. The day before and after the repeated CWI intervention, participants ran in nor...
Source: Applied Physiology, Nutrition, and Metabolism - February 1, 2024 Category: Physiology Authors: Geoffrey Dorsett Felipe Gorini Pereira Matthew Kuennen Kyren Waugh Jackson Barnard Jonluke Bennett Gabriel Garcia Trevor Gillum Source Type: research

Malnutrition care in hospitalized pediatric inpatients: comparison of perceptions and experiences across two pediatric academic health sciences centres
This study represents the largest and most diverse survey of inpatient pediatric HCPs to date. We demonstrate high rates of baseline knowledge of hospital malnutrition, ongoing resource challenges, and the need for a systematic approach to pediatric nutritional management. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - January 30, 2024 Category: Physiology Authors: Jessie M. Hulst Anna de Lange Kristen DaSilva Jillian Owens Louise Bannister Jordan Beaulieu Fariha Chowdhury Bonnie Fleming-Carroll Beth Haliburton Daina Kalnins Sanjay Mahant Sarah McEwan Adelina Morra Lisa Talone Nikhil Pai Source Type: research

Anti-inflammatory effects of sericin and swimming exercise in treating experimental Achilles tendinopathy in rat
This study underscores the potential of sericin and swimming exercises in mitigating inflammation and oxidative stress linked to AT pa thogenesis, presenting a promising combined therapeutic strategy. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - January 29, 2024 Category: Physiology Authors: Koksal Gundogdu Ozgen K ılıc Erkek Gulsah Gundogdu Dilek Sayin Gulcin Abban Mete Source Type: research

A survey of preoperative surgical nutrition practices, opinions, and barriers across Canada
In conclusion, there is a gap between opinion and practice among surgical HCPs pertaining to malnutrition. Although HCPs agreed malnutrition is a surgical priority, the opportunity to screen for nutrition risk was a great barrier. (Source: Applied Physiology, Nutrition, and Metabolism)
Source: Applied Physiology, Nutrition, and Metabolism - January 19, 2024 Category: Physiology Authors: Natalia Tomborelli Bellafronte Roseann Nasser Leah Gramlich Francesco Carli Sender Liberman Daniel Santa Mina Geoff Schierbeck Olle Ljungqvist Chelsia Gillis Source Type: research

Metabolic remodeling of visceral and subcutaneous white adipose tissue during reacclimation of rats after cold
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Deciphering lipid metabolism in white adipose tissue (WAT) depots during weight gain is important to understand the heterogeneity of WAT and its roles in obesity. Here, we examined the expression of key enzymes of lipid metabolism and changes in the morphology of representative visceral (epididymal) and subcutaneous (inguinal) WAT (eWAT and iWAT, respectively)-in adult male rats acclimated to cold (4 ± 1 °C) for 45 days and reacclimated to room temperature (RT, 22 ± 1 °C) for 1, 3, 7, 12, 21, or 45 days. The relative mass of both depots decreased to a sim...
Source: Applied Physiology, Nutrition, and Metabolism - January 19, 2024 Category: Physiology Authors: Marta Budnar Soskic Tamara Zakic Aleksandra Korac Bato Korac Aleksandra Jankovic Source Type: research