Cost-Effectiveness and Value of Information Analysis of an Ambient Intelligent Geriatric Management (AmbIGeM) System Compared to Usual Care to Prevent Falls in Older People in Hospitals
ConclusionsThe benefits to cost ratio suggests that a new trial of the AmbIGeM system in GEMU wards may not be high-value compared to other potential trials, and that the system should be implemented. However, a broader analysis of options for preventing falls in GEMU is required to fully inform decision making.Trial RegistrationAustralian and New Zealand Clinical Trial Registry (ACTRN 12617000981325). (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - December 9, 2022 Category: Health Management Source Type: research

A Guideline-Implementation Intervention to Improve the Management of Low Back Pain in Primary Care: A Difference-in-Difference-in-Differences Analysis
ConclusionsA brief guideline-implementation intervention following best-practice LBP management and guideline-implementation strategies achieved significant reductions, persisting over at least 6 to18 months, in healthcare utilisation consistent with improved delivery of guideline-concordant care. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - December 6, 2022 Category: Health Management Source Type: research

EQ-5D-5L Population Norms for Italy
ConclusionsEQ-5D-5L population norms provide useful insights into the health status of the Italian population and can be used as a reference for other surveys using the same instrument. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 25, 2022 Category: Health Management Source Type: research

Population-Level Impact of Omitting Axillary Lymph Node Dissection in Early Breast Cancer Women: Evidence from an Economic Evaluation in Germany
ConclusionsThe implementation of the Z0011 recommendations resulted in substantial savings and health gain in Germany. Our findings suggest that it is beneficial to introduce additional policy measures to promote further uptake of the Z0011 recommendations in clinical practice. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 21, 2022 Category: Health Management Source Type: research

The Role of Mental Health on Workplace Productivity: A Critical Review of the Literature
ConclusionDespite consistent findings, more high-quality, longitudinal and causal inference studies are needed to provide clear policy recommendations. Moreover, future research should seek to understand how working conditions and work arrangements as well as workplace policies impact presenteeism. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 15, 2022 Category: Health Management Source Type: research

An Item-Response Mapping from General Health Questionnaire Responses to EQ-5D-3L Using a General Population Sample from England
ConclusionThe mapping allows EQ-5D-3L responses to be predicted using GHQ-12 responses, which may be useful in estimating utility values and QALYs. An R script and Microsoft Excel spreadsheet are provided to facilitate calculations. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 14, 2022 Category: Health Management Source Type: research

Determining What Represents Value in the Treatment of Refractory or Unexplained Chronic Cough from the Perspective of Key Stakeholders in Spain Using Multi-Criteria Decision Analysis
ConclusionsRefractory or unexplained chronic cough is a medical condition that seriously impacts patients ’ HRQoL. The primary goal of treatment is to improve patients’ HRQoL by reducing the frequency and intensity of cough. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 2, 2022 Category: Health Management Source Type: research

Economic Effects of Fixed-Dose Versus Loose-Dose Combination Therapy for Type 2 Diabetes Patients
ConclusionAlthough FDC therapy increased disease-specific pharmaceutical spending in the short term, this increase did not lead to differences in total healthcare costs from the payer perspective. From the patient perspective, FDC therapy may be the preferred treatment approach, because of significant saving in co-payments, which is likely attributable to the elimination of one co-payment and therefore a shift in costs to the payer. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 31, 2022 Category: Health Management Source Type: research

Valuation of Costs in Health Economics During Financial and Economic Crises: A Case Study from Lebanon
AbstractIn 2019, we embarked on a study on the economic burden of multiple sclerosis (MS) in Lebanon, in collaboration with a premier Lebanese MS center. This coincided with a triple disaster in Lebanon, comprising the drastic economic and financial crisis, the COVID-19 pandemic, and the consequences of the explosion of Beirut ’s port. Specifically, the economic and financial turmoil made the valuation of costs challenging. Researchers could face similar challenges, particularly in low- and middle-income countries (LMICs) where economic crises and recessions are recurrent phenomena. This paper aims to discuss steps tak ...
Source: Applied Health Economics and Health Policy - October 26, 2022 Category: Health Management Source Type: research

Correction to: Cost Effectiveness of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Patients with Knee Osteoarthritis
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 21, 2022 Category: Health Management Source Type: research

Development of a Health Technology Assessment Quality Appraisal Checklist (HTA-QAC) for India
ConclusionWe recommend a standardised process of quality appraisal to ensure the high quality of HTA evidence for policy use in the Indian context. The proposed HTA-QAC will help authors to ensure standardised reporting, as well as allow reviewers to assess the quality of analysis. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 19, 2022 Category: Health Management Source Type: research

Exploring the Integration of Environmental Impacts in the Cost Analysis of the Pilot MEL-SELF Trial of Patient-Led Melanoma Surveillance
ConclusionCalculating environmental impacts is worthwhile and feasible within a cost analysis framework. Further work is needed to address outstanding conceptual and practical issues so that a comprehensive assessment of environmental impacts can be considered alongside economic costs in health technology assessments. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 5, 2022 Category: Health Management Source Type: research

What Features of Fertility Treatment do Patients Value? Price Elasticity and Willingness-to-Pay Values from a Discrete Choice Experiment
ConclusionInfertile women who had previously undergone or were undergoing fertility treatment valued fertility treatment highly as reflected by highly price-inelastic demand. Success rate of treatment and out-of-pocket costs were the most important attributes and largely determined patients ’ WTP for fertility treatment relative to the attributes and levels used in the study. While further research should investigate the price sensitivity of women who have not experienced fertility treatment, these results might explain why women continue fertility treatment once they have commenced despite their financial capacity to pa...
Source: Applied Health Economics and Health Policy - September 29, 2022 Category: Health Management Source Type: research

The Cost-Effectiveness of Adjunctive Lifestyle Interventions for the Management of Cancer: A Systematic Review
ConclusionsThe evidence to support the cost effectiveness of lifestyle interventions in patients with cancer is mixed with four of the nine interventions found to be cost effective and two remaining cost effective when uncertainty was taken into account. Sensitivity analysis showed the influence of the CE threshold on the results, highlighting the importance of selecting a CE threshold that is appropriate to the setting.Systematic review registration: PROSPERO Registration Number: CRD42020185376. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 27, 2022 Category: Health Management Source Type: research

Cost Effectiveness of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Patients with Knee Osteoarthritis
ConclusionsThe study demonstrated that hUCB-MSC therapy was cost effective compared with microfracture when treating patients with knee OA. These findings should inform health policy decision makers about considerations for cost-effective therapy for treating knee OA to ultimately enhance population health. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 22, 2022 Category: Health Management Source Type: research