Applied Health Economics and Health Policy This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Values in Modelling: Video Series Development and Evaluation Survey
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - July 5, 2023 Category: Health Management Source Type: research

Drug Repurposing of Generic Drugs: Challenges and the Potential Role for Government
AbstractDrug repurposing is the process of identifying a new use for an existing drug or active substance in an indication outside the scope of the original indication. Drug repurposing has important advantages including reduced development time and costs, and potentially large societal healthcare cost savings. However, current generic drug repurposing research faces a number of challenges in obtaining research funds. Furthermore, regardless of the success of a repurposing trial, commercial parties often lack interest in pursuing marketing authorisation for financial reasons, and academic researchers lack the knowledge, ti...
Source: Applied Health Economics and Health Policy - July 3, 2023 Category: Health Management Source Type: research

Correction to: The False Economy of Seeking to Eliminate Delayed Transfers of Care: Some Lessons from Queueing Theory
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - July 3, 2023 Category: Health Management Source Type: research

Cost-Effectiveness of Anti-retroviral Adherence Interventions for People Living with HIV: A Systematic Review of Decision Analytical Models
ConclusionCounselling and smartphone-based interventions are cost-effective, and they have the potential to reduce the chronic adherence problem significantly. The quality of decision models can be improved by addressing inconsistencies in model selection, data inputs incorporated into models and uncertainty assessment methods. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - June 30, 2023 Category: Health Management Source Type: research

A Systematic Review of Cost-Effectiveness Analyses of Colorectal Cancer Screening in Europe: Have Studies Included Optimal Screening Intensities?
ConclusionsThe existing CEA evidence indicates that the widely adopted biennial frequency of stool-based testing in Europe is suboptimal. It is likely that many more lives could be saved throughout Europe if programmes could be offered with more intensive annual screening. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - June 28, 2023 Category: Health Management Source Type: research

Value for Money of CAR-T Cell Therapy for Patients with Diffuse Large B-cell Lymphoma in China: Evidence from a Cost-Effectiveness Analysis
ConclusionOur results demonstrated that CAR-T treatments are not cost effective in any-line settings for DLBCL patients at the WHO-recommended willingness-to-pay threshold (CNY257,241 per QALY) in the base-case analysis. Price reduction of CAR-T therapies is the main approach for lowering ICERs and ensuring that the drug costs are proportional to patient health benefits. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - June 25, 2023 Category: Health Management Source Type: research

Direct Medical Costs of COPD in the USA: An Analysis of the Medical Expenditure Panel Survey 2017 –2018
ConclusionCOPD poses a significant economic burden on healthcare payers and patients 45 years of age and older in the USA. While prescription drugs accounted for almost half of the total cost, more than 10% of the prescription drug cost was out-of-pocket. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - June 3, 2023 Category: Health Management Source Type: research

What About Offering a Financial Incentive Directly to Clinical Units to Encourage the Use of Biosimilars? Results of a Two-Year National Experiment in France
ConclusionThe French experimental incentive appeared to be more effective at increasing biosimilar use. As it is expected to be implemented in all hospitals, the knowledge gained during this testing phase should allow adjustment of some of its terms and increase physician engagement. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - May 30, 2023 Category: Health Management Source Type: research

10 Years of AMNOG: What is the Willingness-to-Pay for Pharmaceuticals in Germany?
ConclusionThis paper is one of the first to estimate the implicit WTP for prescription pharmaceuticals post-AMNOG and suggests that the WTP may vary between different therapeutic areas. Additionally, making different assumptions (approach A versus approach B) with regard to the assumed effectiveness in indication areas that had been declared as having no additional benefit by the FJC may explain the different perspectives of decision-makers and of the pharmaceutical industry on the value of a pharmaceutical. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - May 30, 2023 Category: Health Management Source Type: research

myCOPD App for Managing Chronic Obstructive Pulmonary Disease: A NICE Medical Technology Guidance for a Digital Health Technology
AbstractmyCOPD is a digital tool designed for people to manage their chronic obstructive pulmonary disease (COPD). It requires a device with an internet connection and incorporates tools for education, self-management, symptom tracking and pulmonary rehabilitation (PR). myCOPD was selected for medical technologies guidance by the UK National Institute for Health and Care Excellence (NICE) in 2020. The External Assessment Group (EAG) critiqued the company ’s submission. The evidence comprised four clinical studies (three randomised controlled trials [RCTs] and one observational study) and real-world evidence from 22 docum...
Source: Applied Health Economics and Health Policy - May 28, 2023 Category: Health Management Source Type: research

Symptomatic SARS-CoV-2 Episodes and Health-Related Quality of Life
ConclusionThis evidence-based study highlights the need for targeting of interventions and services towards those experiencing symptomatic episodes during future waves of the pandemic and helps to quantify the benefits of SARS-CoV-2 treatment in terms of health-related quality of life. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - May 27, 2023 Category: Health Management Source Type: research

Modelled Distributional Cost-Effectiveness Analysis of Childhood Obesity Interventions: A Demonstration
ConclusionsThese analyses demonstrated that distributional cost-effectiveness analyses using a fit-for-purpose model are appropriate for differentiating and communicating the efficiency and equity impacts of childhood obesity interventions. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - May 23, 2023 Category: Health Management Source Type: research

Cost ‑Effectiveness of Lorlatinib in First-Line Treatment of Adult Patients with Anaplastic Lymphoma Kinase (ALK)‑Positive Non‑Small‑Cell Lung Cancer in Sweden
ConclusionsThe ICER of SEK613,032 for lorlatinib versus crizotinib falls below the typical willingness-to-pay threshold per QALY gained for high-severity diseases in Sweden (approximately SEK1,000,000). Furthermore, as brigatinib and alectinib were extendedly dominated in the incremental analysis, the results of our study indicate that lorlatinib may be considered a cost-effective treatment option for first-line patients with ALK+ NSCLC in Sweden when compared with crizotinib, alectinib, and brigatinib. Longer-term follow-up data for endpoints informing treatment effectiveness for all first-line treatments would help to re...
Source: Applied Health Economics and Health Policy - May 12, 2023 Category: Health Management Source Type: research

Preferences for Enhanced Primary Care Services Among Older Individuals and Primary Care Physicians
ConclusionsOur study provides timely insights for the development of strategies to support the government ’s new health care initiative (HealthierSG), which places PC at the center of Singapore’s healthcare system. The ability to choose their preferred clinic, low out-of-pocket costs and types of services offered (for users), and reasonable working conditions (for providers) were the key factors for users and providers to participate in enhanced PC services. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - May 9, 2023 Category: Health Management Source Type: research

Public Preferences for Introducing a COVID-19 Certificate: A Discrete Choice Experiment in the Netherlands
ConclusionsPreferences for introduction of a COVID-19 certificate are mixed. A certificate that allows for shopping without appointment and visiting bars and restaurants is likely to increase acceptance. The support of younger citizens and those who plan to get vaccinated seems most sensitive to the specific freedoms granted by a COVID-19 certificate. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - May 8, 2023 Category: Health Management Source Type: research