Green Nanotechnology of < em > Yucca filamentosa < /em > - Phytochemicals-Functionalized Gold Nanoparticles-Antitumor Efficacy Against Prostate and Breast Cancers
CONCLUSION: Overall, these Y. filamentosa phytochemicals functionalized nano-Ayurvedic medicine agents demonstrated selective toxicity to cancer cells while sparing normal cells. Most notably, to our knowledge, this is the first study that shows YF-AuNP's targeting efficacy toward pro-tumor macrophage cell lines, suggesting an immunomodulatory pathway for cancer treatment. This work introduces a novel avenue for herbal and nano-Ayurvedic approaches to human cancer treatment, mediated through selective efficacy and immunomodulatory potential.PMID:38106675 | PMC:PMC10723618 | DOI:10.2147/NSA.S437812 (Source: Appl Human Sci)
Source: Appl Human Sci - December 18, 2023 Category: Physiology Authors: Velaphi C Thipe Ananya Jatar Alice Raphael Karikachery Kavita K Katti Kattesh V Katti Source Type: research
Green Nanotechnology of < em > Yucca filamentosa < /em > - Phytochemicals-Functionalized Gold Nanoparticles-Antitumor Efficacy Against Prostate and Breast Cancers
CONCLUSION: Overall, these Y. filamentosa phytochemicals functionalized nano-Ayurvedic medicine agents demonstrated selective toxicity to cancer cells while sparing normal cells. Most notably, to our knowledge, this is the first study that shows YF-AuNP's targeting efficacy toward pro-tumor macrophage cell lines, suggesting an immunomodulatory pathway for cancer treatment. This work introduces a novel avenue for herbal and nano-Ayurvedic approaches to human cancer treatment, mediated through selective efficacy and immunomodulatory potential.PMID:38106675 | PMC:PMC10723618 | DOI:10.2147/NSA.S437812 (Source: Appl Human Sci)
Source: Appl Human Sci - December 18, 2023 Category: Physiology Authors: Velaphi C Thipe Ananya Jatar Alice Raphael Karikachery Kavita K Katti Kattesh V Katti Source Type: research
Green Nanotechnology of < em > Yucca filamentosa < /em > - Phytochemicals-Functionalized Gold Nanoparticles-Antitumor Efficacy Against Prostate and Breast Cancers
CONCLUSION: Overall, these Y. filamentosa phytochemicals functionalized nano-Ayurvedic medicine agents demonstrated selective toxicity to cancer cells while sparing normal cells. Most notably, to our knowledge, this is the first study that shows YF-AuNP's targeting efficacy toward pro-tumor macrophage cell lines, suggesting an immunomodulatory pathway for cancer treatment. This work introduces a novel avenue for herbal and nano-Ayurvedic approaches to human cancer treatment, mediated through selective efficacy and immunomodulatory potential.PMID:38106675 | PMC:PMC10723618 | DOI:10.2147/NSA.S437812 (Source: Appl Human Sci)
Source: Appl Human Sci - December 18, 2023 Category: Physiology Authors: Velaphi C Thipe Ananya Jatar Alice Raphael Karikachery Kavita K Katti Kattesh V Katti Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | PMC:PMC10697670 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction
CONCLUSIONS: The hSCAPs exhibited properties of MSCs and could differentiate into NSCs under 3D-neurosphere generation. The present findings suggest that NSCs-derived hSCAPs may be used as an alternative candidates for cell-based therapy, which uses stem cell transplantation to further treat neurodegenerative diseases.PMID:37970885 | DOI:10.1590/1678-7757-2023-0209 (Source: Appl Human Sci)
Source: Appl Human Sci - November 16, 2023 Category: Physiology Authors: Anupong Thongklam Songsaad Sarut Thairat Peeratchai Seemaung Amarin Thongsuk Tatcha Balit Nisarat Ruangsawasdi Chareerut Phruksaniyom Thanasup Gonmanee Kenneth L White Charoensri Thonabulsombat Source Type: research
