Dental pain report in children and genetic polymorphism (rs4818) in Catechol-O-Methyltransferase (COMT) gene: a cross- sectional study
CONCLUSIONS: The rs4818 polymorphism of the COMT gene is associated with dental pain. Children with the C allele are more likely to report higher levels of pain. Clinical Relevance: Even though the experience of pain is subjective and multifactorial, this study raises the hypothesis that there is a genetic predisposition to dental pain that should be considered in clinical practice.PMID:38198369 | PMC:PMC10786450 | DOI:10.1590/1678-7757-2023-0229 (Source: Appl Human Sci)
Source: Appl Human Sci - January 10, 2024 Category: Physiology Authors: Bruna Leticia Vessoni Menoncin Aluh ê Lopes Fatturi Rafaela Scariot Jos é Vitor Nogara Borges Menezes Jo ão Armando Brancher Juliana Feltrin-Souza Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
Possible role of ALDH1 and CD44 in lip carcinogenesis
This study aimed to investigate the immunostaining of the putative cancer stem cells (CSC) markers ALDH1 and CD44 in AC (n=30) and LSCC (n=20). ALDH1 positivity was found to be statistically higher in LSCC than in AC lesions (p=0.0045), whilst CD44 expression was statistically higher in AC than in LSCC lesions (p=0.0155). ALDH1+ cells in AC lesions were associated with specific clinical features: a younger age (<60 years old), the female gender, white skin, not smoking or consuming alcohol, and a fast evolution, and not associated with the chronic exposure to UV radiation (p<0.0001). CD44 positivity was associated wi...
Source: Appl Human Sci - December 21, 2023 Category: Physiology Authors: Rafael Carneiro Ortiz Gabriele Gomes Gois Camila Alves Costa N ádia Lago Costa Camila Oliveira Rodini Source Type: research
