Belief in Animal Sentience and Affective Owner Attitudes are linked to Positive Working Equid Welfare across Six Countries
This study used a welfare assessment protocol alongside a questionnaire exploring owner attitudes to assess 378 participants across six countries. Overall, the general health status and body condition of equids belonging to owners with an affective (versus instrumental) perspective and those owners who believed that their equids could feel emotions, were significantly better. Equids belonging to owners who believed that their animals could feel pain were also significantly less likely to be lame. Potential causal relationships between factors and theories explaining these beliefs are discussed. These results can inform fut...
Source: Appl Human Sci - June 29, 2023 Category: Physiology Authors: Emily Haddy Faith Burden Zoe Raw Jo ão B Rodrigues Jaime Humberto Zappi Bello Julia Brown Juliane Kaminski Leanne Proops Source Type: research
Belief in Animal Sentience and Affective Owner Attitudes are linked to Positive Working Equid Welfare across Six Countries
This study used a welfare assessment protocol alongside a questionnaire exploring owner attitudes to assess 378 participants across six countries. Overall, the general health status and body condition of equids belonging to owners with an affective (versus instrumental) perspective and those owners who believed that their equids could feel emotions, were significantly better. Equids belonging to owners who believed that their animals could feel pain were also significantly less likely to be lame. Potential causal relationships between factors and theories explaining these beliefs are discussed. These results can inform fut...
Source: Appl Human Sci - June 29, 2023 Category: Physiology Authors: Emily Haddy Faith Burden Zoe Raw Jo ão B Rodrigues Jaime Humberto Zappi Bello Julia Brown Juliane Kaminski Leanne Proops Source Type: research
Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing
Light Sci Appl. 2023 Jun 27;12(1):161. doi: 10.1038/s41377-023-01199-y.ABSTRACTIn-silico clearing enables deep optical imaging of biological samples by correcting image blur caused by scattering and aberration. This breakthrough method offers researchers unprecedented insights into three-dimensional biological systems, with enormous potential for advancing biology and medicine to better understand living organisms and human health.PMID:37369651 | PMC:PMC10300014 | DOI:10.1038/s41377-023-01199-y (Source: Appl Human Sci)
Source: Appl Human Sci - June 27, 2023 Category: Physiology Authors: Ting-Hui Xiao Yuqi Zhou Keisuke Goda Source Type: research
Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing
Light Sci Appl. 2023 Jun 27;12(1):161. doi: 10.1038/s41377-023-01199-y.ABSTRACTIn-silico clearing enables deep optical imaging of biological samples by correcting image blur caused by scattering and aberration. This breakthrough method offers researchers unprecedented insights into three-dimensional biological systems, with enormous potential for advancing biology and medicine to better understand living organisms and human health.PMID:37369651 | DOI:10.1038/s41377-023-01199-y (Source: Appl Human Sci)
Source: Appl Human Sci - June 27, 2023 Category: Physiology Authors: Ting-Hui Xiao Yuqi Zhou Keisuke Goda Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
Light Sci Appl. 2023 Jun 15;12(1):147. doi: 10.1038/s41377-023-01191-6.ABSTRACTAmyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chemical microscope integrating 3D mid-infrared photothermal imaging with fluorescence imaging, termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography (FBS-IDT). Based on a low-cost and simple optical design, FBS-IDT enables chemical-s...
Source: Appl Human Sci - June 15, 2023 Category: Physiology Authors: Jian Zhao Lulu Jiang Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-Xin Cheng Source Type: research
An in vitro anti-inflammatory effect of Thai propolis in human dental pulp cells
CONCLUSIONS: Upregulated COX-2 expression and enhanced PGE2 synthesis upon treatment with IL-1β in human dental pulp cells were suppressed by incubation with non-toxic doses of Thai propolis extract via involvement of the NF-kB activation. This extract could be therapeutically used as a pulp capping material due to its anti-inflammatory properties.PMID:37283330 | PMC:PMC10247283 | DOI:10.1590/1678-7757-2023-0006 (Source: Appl Human Sci)
Source: Appl Human Sci - June 7, 2023 Category: Physiology Authors: Nutthapong Kantrong Jittranut Kumtawee Teerasak Damrongrungruang Subin Puasiri Anupong Makeudom Suttichai Krisanaprakornkit Pattama Chailertvanitkul Source Type: research
